Aqueous Diels-Alder Reactions Research Articles

Diastereoselection in an aqueous Diels–Alder reaction: a formal total synthesis of the Inhoffen–Lythgoe diol

A formal synthesis of the Inhoffen–Lythgoe diol (1) featuring a novel intermolecular Diels–Alder strategy wherein an intact C(20) stereocentre as part of a diene unit is used to elaborate directly the stereocentres at C(13) and C(17) of the hydrindan ring system of (1), is reported.

Aqueous intermolecular diels-alder chemistry : Reaction of ( e)-2,4-pentadienyl ammonium chloride and related ammonium salts with dienophiles in water

The aqueous Diels-Alder reactions of a series of dienyl ammonium chlorides derived from ( E)-2,4-pentadienylamine, ( E)-3,5-hexadienyl amine and ( E)-4,6-heptadienyl amine with a variety of dienophiles have been examined. A similar Diels-Alder study employing the sodium salt of N-( E)-4,6-heptadienyl succinamic acid in water was also undertaken.

ChemInform Abstract: SYNTHESIS AND REACTIVITY OF (E)‐4,6,7‐OCTATRIENOIC ACID SODIUM SALT IN THE AQUEOUS DIELS‐ALDER REACTION

AbstractDie Verbindung (I) wird ausgehend von Acrolein und Propargylmagnesiumbromid in einer dreistufigen Synthese hergestellt.

On the origin of product selectivity in aqueous diels-alder reactions

The high endo/exo product ratio in the Diels-Alder reaction of cyclopentadiene with methyl vinyl ketone in water does not reflect aggregation, but the ratio is affected by salts which change the hydrophobicity of the medium.

Sodium 6-methoxy-( [formula omitted], [formula omitted])-3,5-hexadienoate: a useful diene in the aqueous diels-alder reaction

The sensitive dienol ether functionality in sodium 6-methoxy-( E , E )-3,5-hexadienoate has been shown to be compatible with the conditions of the aqueous Diels-Alder reaction.