Some indicators that determine the trends in the aquaculture development in the world, such as the number of employed and the volume of aquaculture production by continent have been considered as well as a forecast for the development of the industry in comparison with industrial fisheries and an analysis of the volume and growth rate of aquaculture production in some foreign countries have been given. The essence of regional protectionism in aquaculture has been revealed, its relationship with government programs and strategies for the aquaculture development in the country has been determined, the development and implementation of which are based on the formation of strategic competitive advantages in the global market and ensuring national food security. An analysis of the level of food security by the countries of the world allowed the authors to identify some foreign countries from different regions of the world with various forms of government and to characterize the implementation of regional protectionism in aquaculture in these countries. As a result of evaluating the implementation of regional protectionism in some foreign countries, the authors concluded that the volume of aquaculture production is directly dependent on the effectiveness of protectionism measures in the regions (provinces, states and other domestic territorial entities). In addition, the efforts made by Central authorities to support and develop aquaculture in the country, expressed in the development and active implementation of state programs and strategies, delegation of authority to the regional level, as well as support for the development of informal industry institutions, are a significant factor not only in ensuring food security of the state, but also in increasing the effectiveness of regional protectionism measures in aquaculture.