April 01 Research Articles

The impact of different doses of intrathecal dexmedetomidine used as adjuvant to hyperbaric prilocaine in short ambulatory procedures under spinal anesthesia: a randomized controlled study

Objective: This study aimed to determine the most effective dose of dexmedetomidine as an adjuvant to prilocaine in spinal anesthesia. Methods: Sixty-nine adult patients (21 to 65 y) scheduled for elective surgeries under spinal anesthesia were included in the study. Patients received spinal anesthesia with 3 mL of prilocaine and 0.5 mL dexmedetomidine of dose according to randomization of 5,10 and15 µg (D5, D10 and D15 respectively). Time of the first request of analgesia was set as a primary outcome. Results: Time of the first request of rescue opioid was significantly shorter in D5 group (8 ± 6 h) compared to D15group (21 ± 4 h) (P < 0.018). 24 h of postoperative Nalbuphine consumption was higher in D5 group (4.67 ± 0.59 mg) compared to D15 group (2.5 ± 0.71 mg) (P = 0.012). The onset of sensory and motor blocks was significantly earlier in group D15 and D10 compared to group D5. Group D15 showed a significantly prolonged duration of sensory and motor blockade than Groups D10 and D5. The duration of sensory and motor blockade was significantly prolonged in group D10 compared with group D5 (P < 0.001). Conclusion: 10 and 15 μg dexmedetomidine as an adjuvant to prilocaine in spinal anesthesia shortened the onset of both sensory and motor block, prolonged the duration of sensory block, motor block, and the time to first analgesic. Clinical trial registration: The study was registered on Pan African Clinical Trial Registry (www.pactr.org) (ID: PACTR202204558879194-April 2022). Keywords: Intrathecal Dexmedetomidine; Hyperbaric prilocaine; Ambulatory Surgery; Spinal Anesthesia Citation: Biekhet EG, Elazzazi H, Hussein W, Zedan M, Abdelhamid BM. The impact of different doses of intrathecal dexmedetomidine used as adjuvant to hyperbaric prilocaine in short ambulatory procedures under spinal anesthesia: a randomized controlled study. Anaesth. pain intensive care 2024;28(4):664−672; DOI: 10.35975/apic.v28i4.2509 Received: February 20, 2024; Reviewed: April 01, 2024; Accepted: April 20, 2024

Prevalence and factors associated with depression among cancer patients attending chemotherapy at Jimma University Medical Centre, Jimma, Southwest Ethiopia

BackgroundCancer is a chronic, life-threatening disease that causes depression, stigma, and economic cost in developing countries and most common mental problem among cancer patients on chemotherapy. ObjectivesTo assess the prevalence and factors associated with depression among cancer patients attending chemotherapy at JUMC. MethodsAn institution-based cross-sectional study was conducted. A simple random sampling method was used to select 300 participants and they were interviewed from March 01 to April 01, 2022. Data was collected by using a pretested questionnaire and patient card review. The collected data were coded and entered into Epi Data Manager 4.6 and SPSS version 26 was used for analysis. Those variables with a p-value of 0.25 were candidates for multivariable logistic regressions with a p-value of 0.05, and the association was finally determined by a 95% confidence interval. ResultThe prevalence of depression was 170 (56.6 %), (95 % CI = 50.92, 62.28). Patients who live in urban (AOR = 0.47, 95 % CI: 0.29, 0.78), chewing khat (AOR = 2, 95 %CI: 1.17, 3.53), patients on their first chemotherapy (AOR = 2.8, 95 %CI: 1.17, 6.64), on the second chemotherapy cycles (AOR = 3.51, 95 %CI: 1.57, 7.60), and duration starting chemotherapy for 1–3 months (AOR = 0.36, 95 %CI: 0.18, 0.72) were significantly associated with depression. Conclusion and RecommendationAccording to the findings of this study, depression was highly prevalent among patients on chemotherapy so Jimma Medical Centre should give awareness creation and health education about cancer for the rural community, risks of chewing khat, chemotherapy treatment, and duration of starting chemotherapy.

Comparing efficacy and safety of upfront treatment strategies for anaplastic lymphoma kinase-positive non-small cell lung cancer: a network meta-analysis

Aim: This article is based on our previous research, which was presented as a post at the Congress Aiom 2022 Congress and published in Tumori Journal as Conference Abstract (Tumori J. 2022;108:1–194. doi: 10.1177/03008916221114500). In this paper, a comprehensive presentation of all the achieved results is provided. Several tyrosine kinase inhibitors (TKIs) have been investigated to treat patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC). However, direct comparisons between these TKIs are lacking, with many only being compared to crizotinib. To address this gap, a network meta-analysis was conducted to compare the efficacy and safety of various first-line systemic therapies for ALK-positive NSCLC. Methods: A thorough search of PubMed, Embase, and Cochrane Library was performed to identify randomized controlled trials (RCTs) published between January 01, 2000 and April 01, 2022, and included trials that investigated upfront treatments for this molecular subgroup and reported overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and adverse events (AEs) of grade 3 or higher (grade ≥ 3 AEs). Results: The analysis included 9 RCTs with 2,443 patients receiving eight different treatments: alectinib (at two different dosages), brigatinib, ceritinib, crizotinib, ensartinib, lorlatinib, and chemotherapy. Second and third-generation TKIs significantly prolonged PFS compared to crizotinib, with lorlatinib having the highest probability of yielding the most favorable PFS, followed by alectinib (300 mg or 600 mg). However, only alectinib has been shown to significantly prolong OS compared to crizotinib to date. Lorlatinib appears superior in reducing the risk of central nervous system (CNS) progression, followed by alectinib 600 mg. Ceritinib had the highest rate of AEs, followed by lorlatinib and brigatinib. Conclusions: Based on the network meta-analysis, alectinib and lorlatinib emerged as the most promising upfront treatment options. These treatments provide prolonged disease control while maintaining an acceptable safety profile.

Evaluating early pandemic response through length-of-stay analysis of case logs and epidemiological modeling: A case study of Singapore in early 2020

Abstract It is now known that early government interventions in pandemic management helps in slowing down the pandemic in the initial phase, during which a conservative basic reproduction number can be maintained. There have been several ways to evaluate these early response strategies for COVID-19 during its outbreak globally in 2020. As a novelty, we evaluate them through the lens of patient recovery logistics. Here, we use a data-driven approach of recovery analysis in a case study of Singapore during January 22–April 01, 2020, which is effectively the analysis of length-of-stay in the government healthcare facility, National Center for Infectious Diseases. We propose the use of a data-driven method involving periodization, statistical analysis, regression models, and epidemiological models. We demonstrate that the estimates of reproduction number in Singapore shows variation in different age groups and periods, indicating the success of early intervention strategy in the initial transmission stages of the pandemic.

Role of digital media in vaccination promotion. Second report on VaccinarSinToscana.org experience

Abstract Background Since March 27, 2017, the Department of Health Sciences, University of Florence, has been managing and editing an online portal of medical and scientific information, focused on preventive health care and vaccinations: “VaccinarSinToscana.org” (Get vaccinated in Tuscany). The aim of this study is to analyze website's consultation activity over the past four years by single users, visits and single webpage consultation. Methods VaccinarSinToscana website activity during the study period April 01, 2019-March 31, 2023 was investigated using Google Analytics. Microsoft Excel was used for data analysis. Results During the study period 365,070 new single users visited the portal and nearly 15% of them entered more than once for about 447,000 sessions. A total of 815,800 single web pages were visited individually, with an average of 2.23 web pages consulted per visit and an average session duration of 58 seconds. The largest increase in visits occurred in January 2021-June 2021 with the highest peak in March (155,737 single web pages). The most visited pages were about the national vaccination calendar, regional vaccine clinics, and the types of anti-COVID-19 vaccines available (particularly, the viral vector vaccines). Analysis of socio-demographic characteristics showed that the users most attracted to web consultation were female (57%) and the most ‘digital’ age group was 25-34 (24%). Other age groups account for 14% (18-24 years), 22% (35-44 years), 17% (45-54 years), 13% (55-64 years), and 11% (over 64 years). Mobile phones were the most used devices to access the portal (69%), personal computers for 28% and tablets for 3%. Conclusions The analysis of web pages consultation trend showed a relevant exponential increase of visits in the period January 2021-June 2021. The greatest interest of users, in this period marked by the early stages of the national SARS-CoV-2 vaccination campaign, was for searching news regarding anti-COVID-19 vaccination. Key messages • Institutional websites with evidence-based information could be useful tools for users to increase public confidence in vaccination. • The anti-COVID-19 vaccine campaign has increased website visit, demonstrating how this period has been characterized by curiosity, doubt, and citizens’ search for more information.

COVID-19 associated bacterial infections in intensive care unit: a case control study

We described the secondary bacterial infections (SBI) among COVID-19 patients in comparison with non-COVID-19 patients. We performed a retrospective case–control study between January 01, 2020 and April 01, 2022. Including the adult patients, who stayed ≥ 72 h in intensive care unit (ICU). In total 405 patients were included, 135 had (33.3%) COVID-19, with similar age and gender. The length of stay in ICU was not different (11.4 vs 8.2, p = 0.109), however mean intubation days were higher among COVID-19 cases (6.5 vs 3.8, p = 0.005), SBI were more common among COVID-19 cases (34% vs 10.7%, p < 0.001). Among the patients with pneumonia, the rate of gram-positive bacteria was higher in COVID-19 group than the control group (39% vs 5%, p = 0.006). The predictors for SBI were having COVID-19 (OR: 2.3, Cl 1.25–4.32, p = 0.008), days of intubation (OR: 1.05, Cl 1.01–1.10, p = 0.004), and being male (OR: 2, Cl 1.12–3.58, p = 0.018). The predictors of mortality were COVID-19 (OR: 2.38, Cl 1.28–4.42, p = 0.006), days of intubation (OR: 1.06, Cl 1.03–1.09, p < 0.001), active hematologic malignancy (OR: 3.1, Cl: 1.33–7.28, p = 0.09), active solid tumors (OR: 2.44, Cl 1.21–4.91, p = 0.012), and coronary artery diseases (OR: 1.8, Cl 1.01–3.52, p = 0.045). The most common SBI in COVID-19 patients were methicillin-sensitive Staphylococcus aureus. No carbapenem-resistant Enterobacterales related infections were detected in COVID-19 patients.

Comparison of ARIMA and Exponential Smoothing Models in Prediction of Stock Prices

Stock prices tend to show trends or seasonality or have random walk movements. Time series statistical models developed over time aid prediction of stock prices to assist informed decision-making for investors. These models provide quantitative information to financial specialists at the time of placing their buy–sell orders. The paper compares the movement of two univariate time series using two forecasting models—exponential smoothing and autoregressive integrated moving average (ARIMA) (p; d; q). We predict stock prices of selected 15 companies across three sectors (banking, pharmaceuticals, and Information technology) from NIFTY 50 data for the period April 01, 2016 to March 31, 2021. All these 15 companies are representative constituents of the three sectors within the Nifty 50 index. Performances of models were assessed through forecasting error measures such as root mean square error and mean absolute percentage error. Performances of both models were identical for nine stocks. Prediction based on ARIMA was more accurate for six stocks, whereas exponential smoothing model was a better indicator of stock prices in the case of one stock. However, the differences in error measures of the both the models are marginal, and parsimony principle may drive the choice of model.

COVID-19 as a factor associated with early dental implant failures: A retrospective analysis.

To analyze the effect of COVID-19 on early implant failures and identify potential risk factors for early implant failure, concerning patient- and implant-related factors. This retrospective study is based on 1228 patients who received 4841 implants between March 11, 2020, and April 01, 2022, at Erciyes University Faculty of Dentistry. COVID-19, age and gender of patients, smoking, diabetes, irradiation, chemotherapy, osteoporosis, the implant system, location, and characteristics of implants were recorded. At the implant level, univariate and multivariate generalized estimating equation (GEE) logistic regression was used to examine the effect of explanatory variables on early implant failure. The early implant failure rate was 3.1% at the implant level and 10.4% at the patient level. Smokers showed a significantly higher incidence of early implant failures compared to nonsmokers. (odds ratio (OR; 95% CI): 2.140 (1.438-3.184); p < 0.001). Short implants (≤8 mm) had a higher risk of early implant failure than long implants (≥12 mm) (OR (95% CI): 2.089 (1.290-3.382); p = 0.003). COVID-19 had no significant effect on early implant failure. Smoking and short implants were associated with a higher risk for early implant failures.

Serratus anterior plane block versus thoracic epidural block in patients undergoing thoracotomy: a randomized double-blind trial

Background &amp; Objective: Standard pain management technique after thoracic surgery is thoracic epidural analgesia, parentral analgesics and nerve blocks. Thoracic epidural analgesia (TEA) has many known complications, including respiratory depression and urinary retention. Serratus anterior plane block (SAPB) is a simple procedure, which provides postoperative pain relief by blocking the lateral cutaneous branches of T2–T9 spinal neurons. We compared the analgesic efficacy of both of these techniques in thoracotomy patients in this randomized trial.&#x0D; Methodology: The study involved 74 cancer patients scheduled for thoracotomy. The patients were randomly divided into two groups. The patients in Group SAPB underwent ultrasound-guided serratus anterior plan block (SAPB) with catheter insertion. The second group (Group TEA) underwent TEA with preoperative indwelling catheter insertion. In both groups blocks were activated before induction of routine general anesthesia (GA) by a bupivacaine bolus dose, then continued as bupivacaine infusion in ICU for postoperative analgesia. Hemodynamic monitoring was started. Intraoperative fentanyl consumption, postoperative morphine consumption, and time to first request for analgesic were noted including MAP in the two groups.&#x0D; Results: Both groups were statistically comparable regarding intraoperative fentanyl consumption, postoperative morphine consumption, and time to first request for analgesia in the two groups. Hypotensive episodes were significantly more frequent (P &lt; 0.001) in the TEA group (n = 17; 45.9%) compared to the Group SAPB (n = 2; 5.4%). Ramsey sedation scores (RSS) were comparable in the two groups immediately postoperatively and after 2 h. After 4 h after recovery all patients in both groups had an RSS of 2.&#x0D; Conclusion: Ultrasound-guided serratus anterior plane block is associated with reduced intraoperative and postoperative fentanyl consumption, but the Ramsey sedation scores were equivalent in the two groups after recovery and upto 4h.&#x0D; Abbreviations: GA: General Anesthesia; PTPS: Post-Thoracotomy Pain Syndrome: RSS: Ramsey Sedation Score; SAPB: Serratus Anterior Plane Block; TEA: Thoracic Epidural Analgesia; VATS: Video-Assisted Thoracoscopic Surgery&#x0D; Key words: Pain, Postoperative; Serrataus plane block; Thoracotomy; Ultrasound; Thoracic epidural&#x0D; Citation: Gamal RM, Bossily SS, Ali AR, Samy SF, Seif NE, Ahmed HI. Serratus anterior plane block versus thoracic epidural block in patients undergoing thoracotomy: a randomized double-blind trial. Anaesth. pain intensive care 2023;27(3):389−395.&#x0D; DOI: 10.35975/apic.v27i3.2243&#x0D; Received: March 06, 2023; Reviewed: March 31, 2023; Accepted: April 01, 2023

First clinical experience with posterior lumbar interbody fusion using a thermal-sprayed silver-containing hydroxyapatite-coated cage

BackgroundTo investigate the possibility of silver (Ag)-induced adverse events and the degree of bone fusion in posterior lumbar interbody fusion surgery using an Ag-containing hydroxyapatite (HA) lumbar interbody cage.MethodsAn Ag-HA cage consisting of highly osteoconductive HA interfused with Ag was developed, and we applied it clinically at three university-affiliated hospitals from April 2020 to December 2020. During the 12-month postoperative observation period, Ag-related adverse events, neuropathy, and postoperative complications were investigated as indicators of safety, while clinical improvement and the fusion status were investigated as indicators of efficacy. Clinical improvement was defined as improvement beyond the minimum clinically important difference (MCID) in the numerical rating scale (NRS; 1.6) for low back and lower limb pain and the Oswestry Disability Index (ODI; 12.8).ResultsWe performed lumbar interbody fusion using an Ag-HA cage for 48 patients (female, n = 25; mean age, 67.5 years). The mean preoperative NRS was 6.4 (standard deviation, 1.9), while the mean preoperative ODI was 44 [12]. No adverse effects (i.e., argyria) were identified during the 12-month observation period. Surgical site infection occurred in one case, although the implant was preserved via immediate debridement. In total, 39 (81%) participants showed clinical improvement beyond MCID for both NRS and ODI. Bone fusion was achieved at 45 levels (88%) at 6 months and 48 levels (91%) at 12 months postoperatively.ConclusionsThe results of this study suggest that Ag-HA cages can be safely used in spinal fusion procedures and have the potential to prevent postoperative infections, prevent deterioration of the quality of life, and result in favorable outcomes. Larger-scale and longer-term follow-up studies will be required to corroborate these conclusions.Trial registration UMIN 000039964 (date: April 01, 2020).

An Insula-Enriched Regulator of Retinoic Acid Marks a New Intersection in the Neural Circuitry of Mouse Social Behavior

An Insula-Enriched Regulator of Retinoic Acid Marks a New Intersection in the Neural Circuitry of Mouse Social Behavior

Insights From Genetic, Neuroimaging, and Behavioral Neuroscience Studies.

Back to table of contents Next article Editor’s NoteNo AccessInsights From Genetic, Neuroimaging, and Behavioral Neuroscience StudiesNed H. Kalin, M.D.Ned H. KalinSearch for more papers by this author, M.D.Published Online:1 Apr 2023https://doi.org/10.1176/appi.ajp.20230127AboutSectionsView articleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View article Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byNone Volume 180Issue 4 April 01, 2023Pages 253-255 Metrics KeywordsGeneticsNeuroimagingstressPDF download History Published online 1 April 2023 Published in print 1 April 2023

Guilt by Association: Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders

Guilt by Association: Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders

Psychiatric Advance Directives: A Call for Humanization

Psychiatric Advance Directives: A Call for Humanization

The PhD Odyssey

Research Article| April 01 2023 The PhD Odyssey: Retrospective Reflections on the Notion of “Care” Sasi Kiran R. Mallam Sasi Kiran R. Mallam Sasi Kiran R. Mallam is an assistant professor at FLAME University in Pune, India. He holds a PhD in communication from the University of Hyderabad. He teaches cultural studies and communication with a focus on media history. email: sasikiranreddy@gmail.com Search for other works by this author on: This Site PubMed Google Scholar email: sasikiranreddy@gmail.com Journal of Autoethnography (2023) 4 (2): 283–286. https://doi.org/10.1525/joae.2023.4.2.283 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Sasi Kiran R. Mallam; The PhD Odyssey: Retrospective Reflections on the Notion of “Care”. Journal of Autoethnography 1 April 2023; 4 (2): 283–286. doi: https://doi.org/10.1525/joae.2023.4.2.283 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentJournal of Autoethnography Search [Neoliberalism] has pervasive effects on ways of thought to the point where it has become incorporated into the common-sense way many of us interpret, live in, and understand the world.1 My critical autoethnographic account reflects on the lived experience of being a PhD scholar inhabiting a neoliberal public education space. It is written from a position of caste and class privilege, mindful of the trials and tribulations of less privileged fellow research scholars, who face unimaginable obstacles in the pursuit of their doctoral degrees. The attempt is not just to highlight the inconvenience caused to me but to reflect on the structures erected by neoliberalism that make pursuing a PhD a traumatic experience prone with vulnerabilities. I reflect on the precarity of doing a PhD in a public university in India after the normative age, the resulting anxiety, and notions of care. When I discussed my plans of pursuing... You do not currently have access to this content.

Introduction

Introduction| April 01 2023 Introduction Devina Sarwatay Devina Sarwatay Search for other works by this author on: This Site PubMed Google Scholar Journal of Autoethnography (2023) 4 (2): 275–276. https://doi.org/10.1525/joae.2023.4.2.275 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Devina Sarwatay; Introduction. Journal of Autoethnography 1 April 2023; 4 (2): 275–276. doi: https://doi.org/10.1525/joae.2023.4.2.275 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentJournal of Autoethnography Search To be a young researcher in the social sciences comes with its own set of challenges and learning opportunities. This Forum engages with the complications in conducting “care-full” inquiry when still in a learning/early mode of methods and ethical practice. We highlight autoethnographic narratives1 of early career researchers ranging from talking about the self and surrounding environment to the possibility of looking inward to understand and take the community forward, and from drawing resonance with text to (re)designing mechanisms for academic contemplation. Using autoethnographic accounts of care, or lack thereof, experienced by the scholars, their personal narratives have been tied to broader social and cultural,2 political, and economic contexts of their local realities for reflection on and recommendations for inclusivity such that richer engagement with the field can be undertaken for newer, nuanced meanings to emerge. Aditya Deshbandhu, University of Exeter, emphasizes the necessity of weaving an element... You do not currently have access to this content.

Review: Vital Voids: Cavities and Holes in Mesoamerican Material Culture, by Andrew Finegold

Book Review| April 01 2023 Review: Vital Voids: Cavities and Holes in Mesoamerican Material Culture, by Andrew Finegold Vital Voids: Cavities and Holes in Mesoamerican Material Culture, by Andrew Finegold. Austin: University of Texas Press, 2021. 165 pages. Hardcover $60.00. Jillian Mollenhauer Jillian Mollenhauer Metropolitan State University of Denver Search for other works by this author on: This Site PubMed Google Scholar Latin American and Latinx Visual Culture (2023) 5 (2): 147–148. https://doi.org/10.1525/lavc.2023.5.2.147 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Jillian Mollenhauer; Review: Vital Voids: Cavities and Holes in Mesoamerican Material Culture, by Andrew Finegold. Latin American and Latinx Visual Culture 1 April 2023; 5 (2): 147–148. doi: https://doi.org/10.1525/lavc.2023.5.2.147 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentLatin American and Latinx Visual Culture Search In 1958, Yves Klein’s exhibition La spécialisation de la sensibilité à l'état matière première en sensibilité picturale stabilisée, Le Vide (The Specialization of Sensibility in the Raw Material State of Stabilized Pictorial Sensibility, The Void) firmly embedded artistic notions of the void within a specifically Western, modernist framework of absence and the immaterial. Klein’s exhibition can be situated as part of a continuum of formal experimentation in the twentieth century that was preceded by the pictorial holes of Rauschenberg's “blank” white canvases and Erased de Kooning Drawing (1953), and later succeeded by numerous examples of individual works and entire exhibitions evoking empty space or palpable absence. Within this field of what might be considered the “aesthetics of absence,” Andrew Finegold’s Vital Voids stands as an important counterpoint, highlighting an aesthetic and metaphysical system that positions the void as a space of creation, fecundity, and transformation. Books about Indigenous aesthetics in... You do not currently have access to this content.

Erratum

Correction| April 01 2023 Erratum Current History (2023) 122 (843): i. https://doi.org/10.1525/curh.2023.122.843.i Connected Content This is a correction to: Finland and Sweden’s Road to NATO Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Erratum. Current History 1 April 2023; 122 (843): i. doi: https://doi.org/10.1525/curh.2023.122.843.i Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentCurrent History Search Erratum: In the March 2023 issue of Current History, in the article “Finland and Sweden’s Road to NATO,” by Tuomas Forsberg, the year should be 2013, not 2016, in this sentence on p. 93: Sweden had faced a provocative Russian violation of the airspace near Gotland Island in the Baltic Sea on Easter in 2013, and subsequently had bolstered its readiness, reintroducing military conscription. You do not currently have access to this content.

Nothing but Noise: Timbre and Musical Meaning at the Edge, by Zachary Wallmark

Review| April 01 2023 Nothing but Noise: Timbre and Musical Meaning at the Edge, by Zachary Wallmark Nothing but Noise: Timbre and Musical Meaning at the Edge, by Zachary Wallmark. New York: Oxford University Press, 2022. xiii, 215 pp. Thomas Patteson Thomas Patteson THOMAS PATTESON is a member of the Musical Studies Faculty at the Curtis Institute of Music. Recent publications include a cowritten essay and two translations in the Oxford Handbook of Timbre (2021), which won the 2022 Ruth A. Solie Award from the American Musicological Society. His current research interests include the history and philosophy of musical improvisation and cross-cultural perspectives on music and consciousness. He plays instruments, too: keyboard, alto saxophone, and modular synthesizer. Search for other works by this author on: This Site PubMed Google Scholar Journal of the American Musicological Society (2023) 76 (1): 249–252. https://doi.org/10.1525/jams.2023.76.1.249 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Thomas Patteson; Nothing but Noise: Timbre and Musical Meaning at the Edge, by Zachary Wallmark. Journal of the American Musicological Society 1 April 2023; 76 (1): 249–252. doi: https://doi.org/10.1525/jams.2023.76.1.249 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentJournal of the American Musicological Society Search With this book, Zachary Wallmark has made an ambitious contribution to the famously elusive study of musical timbre. Efforts to integrate the sciences and the humanities, however nobly intentioned, are understandably dogged by the suspicion that one side of the equation is going to end up—to paraphrase Orwell—more equal than the other. But Wallmark succeeds admirably in avoiding the shortcomings of both the scientific desire to study sound in isolation from the messiness of human subjectivity and the humanistic reduction of musical experience to the arbitrary play of cultural difference. His book is perhaps best viewed as an attempt not so much to bridge the “two cultures” as to harmonize their best qualities. In the first chapter, Wallmark boldly proposes a conceptual model for the full spectrum of sonic phenomena, from the generative act to the arbitrary symbolic dimension of sound in human consciousness, and everything in between. This is... You do not currently have access to this content.

Brief Reviews

Other| April 01 2023 Brief Reviews American Literary Realism (2023) 55 (3): 282. https://doi.org/10.5406/19405103.55.3.11 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Brief Reviews. American Literary Realism 1 April 2023; 55 (3): 282. doi: https://doi.org/10.5406/19405103.55.3.11 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressAmerican Literary Realism Search Advanced Search Gary Scott Smith, Mark Twain: Preacher, Prophet, and Social Philosopher. New York: Oxford Univ. Press, 2021. 272 pp. Cloth, $40.00. Smith's biography is the latest volume in a long tradition in Twain scholarship that includes Louis J. Budd's Mark Twain: Social Philosopher (1964); The Bible According to Mark Twain, edited by Howard Baetzhold and Joseph McCullough (1996); Joe B. Fulton's The Reverend Mark Twain (2006); and Harold Bush's Mark Twain and the Spiritual Crisis of His Age (2007). As a result, it offers mostly warmed-over observations and few new insights. (GS)Alan Gribben, Mark Twain's Literary Resources: A Reconstruction of His Library and Reading, volume 2 (Montgomery: NewSouth Books, 2022). 1088 pp. Cloth, $45.00. The second volume of Gribben's monumental Mark Twain's Literary Resources is not exactly a sequel of his long-out-of-print Mark Twain's Library: A Reconstruction (1980) but a vastly expanded revision of it. No doubt... You do not currently have access to this content.