The design of trajectory tracking controllers for smart driving cars still faces problems, such as uncertain parameters and it being time-consuming. To improve the tracking performance of the trajectory tracking controller and reduce the computation of the controller, this paper proposes an improved model predictive control (MPC) method based on fuzzy control and an online update algorithm. First, a vehicle dynamics model is constructed and a feedforward MPC controller is designed; second, a real-time updating method of the time domain parameters is proposed to replace the previous method of empirically selecting the time domain parameters; lastly, a fuzzy controller is proposed for the real-time adjustment of the weight coefficient matrix of the model predictive controller according to the lateral and heading errors of the vehicle, and a state matrix-based cosine similarity updating mechanism is developed for determining the updating nodes of the state matrix to reduce the controller computation caused by the continuous updating of the state matrix when the longitudinal vehicle speed changes. Finally, the controller is compared with the traditional model prediction controller through the co-simulation of CARSIM and MATLAB/Simulink, and the results show that the controller has great improvement in terms of tracking accuracy and controller computational load.