Acoustic radiation force has been used in many interesting medical and industrial applications in the past two decades. The fact that radiation stress can be confined to a small focal area and exerted remotely inside or on an object allows one to use this phenomenon in a variety of ways to explore properties of the object. Vibro-acoustography is a material characterization and imaging method that uses harmonic or impulsive acoustic radiation force to stimulate the targeted material and receives the resulting acoustic response. The output acoustic signal is then used to extract important information about the object. Biomedical applications of vibro-acoustography and its closely related methods include imaging, flow detection, and tissue characterization. Other applications include non-destructive evaluation/testing of materials, modal analysis of small structures, and microscopy. This talk presents an overview of vibro-acoustography and its closely related techniques over the past 20 years. Various biomedical and industrial applications will be presented. The talk will conclude with a discussion on potential future applications of this technology.