Orthodontic Application Research Articles

Bioactive Coatings Loaded with Osteogenic Protein for Metallic Implants.

Osteoconductive and osteoinductive coatings represent attractive and tunable strategies towards the enhanced biomechanics and osseointegration of metallic implants, providing accurate local modulation of bone-to-implant interface. Composite materials based on polylactide (PLA) and hydroxyapatite (HAp) are proved beneficial substrates for the modulation of bone cells’ development, being suitable mechanical supports for the repair and regeneration of bone tissue. Moreover, the addition of osteogenic proteins represents the next step towards the fabrication of advanced biomaterials for hard tissue engineering applications, as their regulatory mechanisms beneficially contribute to the new bone formation. In this respect, laser-processed composites, based on PLA, Hap, and bone morphogenetic protein 4(BMP4), are herein proposed as bioactive coatings for metallic implants. The nanostructured coatings proved superior ability to promote the adhesion, viability, and proliferation of osteoprogenitor cells, without affecting their normal development and further sustaining the osteogenic differentiation of the cells. Our results are complementary to previous studies regarding the successful use of chemically BMP-modified biomaterials in orthopedic and orthodontic applications.

Artificial Intelligence in Orthodontic Smart Application for Treatment Coaching and Its Impact on Clinical Performance of Patients Monitored with AI-TeleHealth System.

Background: Treatment of malocclusion with clear removable appliances like Invisalign® or Spark™, require considerable higher level of patient compliance when compared to conventional fixed braces. The clinical outcomes and treatment efficiency strongly depend on the patient’s discipline. Smart treatment coaching applications, like strojCHECK® are efficient for improving patient compliance. Purpose: To evaluate the impact of computerized personalized decision algorithms responding to observed and anticipated patient behavior implemented as an update of an existing clinical orthodontic application (app). Materials and Methods: Variables such as (1) patient app interaction, (2) patient app discipline and (3) clinical aligner tracking evaluated by artificial intelligence system (AI) system—Dental monitoring® were observed on the set of 86 patients. Two 60-day periods were evaluated; before and after the app was updated with decision tree processes. Results: All variables showed significant improvement after the update except for the manifestation of clinical non-tracking in men, evaluated by artificial intelligence from video scans. Conclusions: Implementation of application update including computerized decision processes can significantly enhance clinical performance of existing health care applications and improve patients’ compliance. Using the algorithm with decision tree architecture could create a baseline for further machine learning optimization.

Femtosecond laser surface roughening and pulsed plasma polymerization duplex treatment on medical-grade stainless steel substrates for orthodontic purpose

This study developed a surface modification technique to obtain nearly superamphiphobic films on AISI 304 stainless steel substrates, which are usually made into dental appliances in orthodontics for malocclusion. Direct fabrication of micro- and nanoscale roughened surfaces on stainless steel substrates were treated using femtosecond laser (FL) processing. Subsequently, pulsed plasma polymerization (P3) was adopted using hexamethyldisiloxane (C6H18OSi2) and octafluorocyclobutane (C4F8) as the precursors to deposit siloxane and fluorocarbon stacking films. The surface characteristics of the deposited films were examined, and in vitro cytotoxicity and antimicrobial tests were performed. Experimental results showed that the surfaces treated by FL and P3 processes exhibited nearly superamphiphobicity with water apparent contact angle (CA) 160°, advancing CA 161°, receding CA160°, contact angle hysteresis (CAH) 1°; sunflower oil apparent contact angle 146°, advancing CA 141°, receding CA137°, CAH 4°; and hexadecane oil apparent contact angle 124°, advancing CA 118°, receding CA113°, contact angle hysteresis CAH 5°, respectively. The nearly superamphiphobicity are attributed to the synergistic effects of pre-roughening by the FL process and post-flourinating with siloxane and fluorocarbon coating by the P3 process, which were consistent with the results of scanning electron microscopy, energy-dispersive X-ray spectroscopy and Fourier transform infrared analyses. In addition, the steel wool abrasion test exhibited the film's surface wear resistance, and in vitro tests revealed the film's non-cytotoxicity and effective inhibition of bacterial growth. Thus, the nearly superamphiphobic coating may be beneficial for applications in orthodontics.

Trueness of full-arch IO scans estimated based on 3D translational and rotational deviations of single teeth\u2014an in vitro study

ObjectivesTo three-dimensionally evaluate deviations of full-arch intraoral (IO) scans from reference desktop scans in terms of translations and rotations of individual teeth and different types of (mal)occlusion.Materials and methodsThree resin model pairs reflecting different tooth (mal)positions were mounted in the phantom head of a dental simulation unit and scanned by three dentists and three non-graduate investigators using a confocal laser IO scanner (Trios 3®). The tooth-crown surfaces of the IO scans and reference scans were superimposed by means of best-fit alignment. A novel method comprising the measurement of individual tooth positions was used to determine the deviations of each tooth in the six degrees of freedom, i.e., in terms of 3D translation and rotation. Deviations between IO and reference scans, among tooth-(mal)position models, and between dentists and non-graduate investigators were analyzed using linear mixed-effects models.ResultsThe overall translational deviations of individual teeth on the IO scans were 76, 32, and 58 µm in the lingual, mesial, and intrusive directions, respectively, resulting in a total displacement of 114 µm. Corresponding rotational deviations were 0.58° buccal tipping, 0.04° mesial tipping, and 0.14° distorotation leading to a combined rotation of 0.78°. These deviations were the smallest for the dental arches with anterior crowding, followed by those with spacing and those with good alignment (p < 0.05). Results were independent of the operator’s level of education.ConclusionsCompared to reference desktop scans, individual teeth on full-arch IO scans showed high trueness with total translational and rotational deviations < 115 µm and < 0.80°, respectively.Clinical relevanceAvailable confocal laser IO scanners appear sufficiently accurate for diagnostic and therapeutic orthodontic applications. Results indicate that full-arch IO scanning can be delegated to non-graduate dental staff members.

Effect of Honey on Orthodontic Tooth Movement and Osteoclastic Activity in Psychologically Stressed Animals

Introduction: Orthodontics is a clinical specialty in dentistry related to the correction of dentofacial deformities. Psychological stress factors delay Orthodontic tooth movement (OTM). Honey can be considered a useful and harmless natural product to reduce stress levels, hence improves the efficacy of OTM.&#x0D; Aims &amp; Objectives: To compare the differences in the rate of tooth movement and osteoclastic activity between control, psychologically stressed and honey treated psychologically stressed groups after 1 week of orthodontic force application in an animal model.&#x0D; Place and duration of study: This experimental study was conducted at the animal research laboratory and Histopathology Department of Post Graduate Medical Institute (PGMI), Lahore, Pakistan, from April 2019 to June 2020.&#x0D; Material &amp; Methods: Thirty-six Sprague Dawley rats were randomly divided into A, B and C groups. Psychological Stress was induced in group A (PS group) while Honey was given orally as a therapeutic agent along with induction of psychological stress in group B (PSH group), and group C was the Control Group. Statistical analyses were performed using SPSS version 24 software. The quantitative variables were the orthodontic tooth movement, the osteoclast count, and the expression of RANKL. One-way ANOVA was applied to calculate the mean difference and Post hoc Tukey test applied for multiple comparisons among the groups. A p-value ? 0.05 was considered statistically significant in all 3 groups.&#x0D; Results: There was a significant difference (p-value &lt;0.05) between control and experimental groups in the orthodontic tooth movement and levels of RANKL, however, there was no significant difference between PS and PSH groups.&#x0D; Conclusion: Psychological stress delays orthodontic tooth movement by causing a reduction in its rate and osteoclastic activity and honey has no significant correlation with lowering stress levels, hence does not improve orthodontic tooth movement efficiency.

PERILAKU REMAJA TERHADAP PENGGUNAAN ORTODONTI CEKAT PADA SISWA SMA DON BOSCO PADANG

Nowadays, the shifting of fixed orthodontic function becomes a lifestyle is more popular than before. The study is purpose to determine a relationship between teenager behaviour (knowledge, attitudes, and action) to fixed orthodontic appliance.This study using cross sectional study design. The sample was a high school students of Don Bosco Padang, Sumatera Barat. The number of samples are 90 people, that chosen by proportionate stratified random sampling technique. The data was collected by using a questionnaire to measure the level of knowledge, attitude and action. Data analysis using Chi-Square test. The result showed there was no significant relationship between teenager knowledge, attitude, and action with fixed orthodontic application in high school students of Don Bosco Padang. The conclusion from this study is that most of high school students of Don Bosco Padang have a high knowledge, positive attitude, and good action about fixed orthodontic treatment

Platelet-rich plasma: Its applications in orthodontics – A systematic review

Objectives: The aim of this systematic review was to assess the available literature for the effects of platelet-rich plasma (PRP) in orthodontics. Material and Methods: This review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (PRISMA). The following databases were searched up to May 2020: Medline (through PubMed), Cochrane, and Google Scholar, and reference lists of the included studies were screened. Randomized controlled trials (RCTs) and controlled clinical trials using PRP an adjunct with the standard orthodontic procedures including animal and human subjects as participants were included in the study. The quality of the included human RCTs was assessed per the revised Cochrane risk-of-bias tool for randomized trials (RoB 2.0), whereas the risk of bias of the included animal studies was assessed using SYRCLES’s RoB tool. Results: Eight studies, six animal and two human studies, fulfilled the inclusion criteria. Three animal studies and one human RCT reported that PRP increased the rate of tooth movement when used as an adjunct along with orthodontic treatment. Conclusion: According to the currently available literature, PRP is an efficient non-invasive method of tooth acceleration, but as most of the studies carried are on animals and cannot be applied to humans indistinctly.

Machine learning in orthodontics: Challenges and perspectives.

Artificial intelligence (AI) applications have significantly improved our everyday quality of life. The last decade has witnessed the emergence of up-and-coming applications in the field of dentistry. It is hopeful that AI, especially machine learning (ML), due to its powerful capacity for image processing and decision support systems, will find extensive application in orthodontics in the future. We performed a comprehensive literature review of the latest studies on the application of ML in orthodontic procedures, including diagnosis, decision-making and treatment. Machine learning models have been found to perform similar to or with even higher accuracy than humans in landmark identification, skeletal classification, bone age prediction, and tooth segmentation. Meanwhile, compared to human experts, ML algorithms allow for high agreement and stability in orthodontic decision-making procedures and treatment effect evaluation. However, current research on ML raises important questions regarding its interpretability and dataset sample reliability. Therefore, more collaboration between orthodontic professionals and technicians is urged to achieve a positive symbiosis between AI and the clinic.

COMPARISON FOR CARICA PAPAYA AND GENGIGEL LEAVES EXTRACTION FOR GINGIVITIS HEALING EFFECTIVENESS IN ORTHODONTIC APPLICATION

Background: Gingivitis is the infection disease with tooth loss effect. Using fixed orthodontic appliance in dentistry can give gingivitis impact with its’ designed way. To determine the effectiveness of papaya leaf extraction and gengigel in gingivitis treatment with fixed orthodontic application in letrature review explanation Methods: Literature searching with Science Direct, NCBI (PubMed), and Google Scholar databases and getting 530 articles. Articles are screened to be 67 articles and selected by inclusion and exclusion criteria getting 37 articles. 37 Articles are ready to be analysed. Results:There is effectiveness of papaya leaf extract and gengigel in patients using fixed orthodontic appliances for giving anti inflammation effect, wound healing and enhance blood circulation. Conclusion: The conclusion is papaya and gengigel leaf extraction giving gingivitis healing effect in fixed orthodontic treatment

Comparison of the effects of horizontal and vertical micro-osteoperforations on the biological response and tooth movement in rabbits.

ObjectiveThis study aimed to compare the amount of tooth movement after multiple horizontal (MH) and single vertical (SV) micro-osteoperforations (MOPs), and evaluate the histological changes after orthodontic force application in rabbits.MethodsThe mandibles of 24 white rabbits were subjected to two experimental interventions MH and SV MOPs. Defect volume of the MOPs between the two groups was kept similar. A force of 100 cN was applied via a coil spring between the incisor teeth and the first premolars. The amount of tooth movement was measured. Differences in the amount of tooth movement and bone variables at three time points and between the two groups were evaluated using repeated-measures analysis of variance.ResultsThe first premolar showed a mesial movement of 1.47 mm in the MH group and 1.84 mm in the SV group, which was significantly different at Week 3 (p < 0.05). No significant difference was observed in bone volume and bone fraction between the groups. Tartrate-resistant acidic phosphatase-positive cell count was also significantly greater at Week 3 than at Week 1 in both the SV and MH groups.ConclusionsThe amount of tooth movement showed significant differences between Weeks 1 and 3 in the SV and MH MOP groups, but showed no differences between the two groups. Therefore, SV MOP could be considered an effective tool for enhancing tooth movement, especially for molar distalization, uprighting, and protraction to an edentulous area.

Surgical Alteration of Occlusal Plane Angulation Followed by Orthodontic Application of TADs and Yin-Yang Arch Wire in Hypodivergent Prognathic Malocclusion

Surgical Alteration of Occlusal Plane Angulation Followed by Orthodontic Application of TADs and Yin-Yang Arch Wire in Hypodivergent Prognathic Malocclusion

Abstracts from the World Federation for Laser Dentistry—Asia Pacific Division Virtual Conference July 16–17, 2021

Abstracts from the World Federation for Laser Dentistry—Asia Pacific Division Virtual Conference July 16–17, 2021

Augmented reality in orthodontics: The way ahead

Augmented Reality is a favorable and definitive pedagogical approach for integrating formal learning. E-learning combined with Augmented Reality (AR) technology can surpass traditional learning methods if the system is tailored to include components of smart learning and evaluation of knowledge on devices ubiquitously in the absence of tutors. AR is predicted to transform and become the fundamental user interface of the twenty-first century. Augmented reality, instead, generates an interaction between the real environment and virtual objects. The use of augmented reality permits direct visualization bypassing the last transfer step, which means, on a large scale, to avoid data and time loss. Visualization of digital data directly on the patient means the possibility of achieving great advantages in digital procedures. This review briefly summarizes history, definitions, features and components of augmented reality technology and discusses its avenues and applications in orthodontics.

Structural, Mechanical, and Decorative Properties of Sputtered TiN and Ti (N, C) Films for Orthodontic Applications; an In Vitro Study.

In this paper, we explore and modify the structural, mechanical, and decorative properties of films composed by TiN and Ti (N, C) with a wide range of N2 gas flow during the deposition in order to be used on orthodontic systems. The films were grown using reactive DC magnetron sputtering from a pure Ti target and customized with C pellets onto Si and stainless steel 316L substrates. The structural properties were studied using X-ray diffraction and scanning electron microscopy, while the mechanical ones were obtained through hardness, elastic modulus, and friction coefficient. Moreover, the wear rate has been measured under an artificial saliva medium to simulate the oral cavity. The color of the films deposited onto stainless steel 316 L substrate was characterized through CIELab color code. Our findings show that the addition of N2 and C in the Ti matrix improves the mechanical properties of the films. With the increase in the amount of N2 and C, the hardness reaches a value of 739 HV, higher than the one reported in the literature (600 HV), a low value of the coefficient of elasticity (8.0 GPa), and also a low friction coefficient (0.30). Moreover, with the addition of N2 and C in the Ti films, the color of the films changes from metallic aspect until “with” gold, which means that our coatings exhibit versatile mechanical and color characteristics to be used in orthodontic wires applications.

Biochemical Changes Between Rapid And Conventional Orthodontic Tooth Movement: A Comparative Studya

Background: Accelerated orthodontics has revolutionized the field of orthodontic treatment. Reducing the overall treatment time remains the prime concern of an orthodontist. A good accelerating technique should be affordable, repeatable, practical, efficient and should not have any side effects on periodontium including root and alveolar bone. In the era of technology, many advances are made and newer techniques for accelerating orthodontic tooth movement have been introduced in order to reduce the length of treatment with minimal risk of side effects. This study was conducted to compare the biochemical changes in rapid and conventional orthodontic tooth movement.&#x0D; Materials and Method:A split mouth study was conducted on thirty patients undergoing fixed orthodontic treatment requiring all four first premolar extraction. The extraction space closure, was carried out with micro osteoperforations on the distal aspect of both the maxillary canines along with orthodontic force application as experimental site on the right side and conventional orthodontic tooth movement as control site on the left side. GCF was collected before the micro osteoperforation (T0), at day 3 (T1), at day 7 (T2) and at 4 weeks (T3) of initiating canine retraction from the distal gingival crevice of both the maxillary canines. Quantitative analysis of IL-1 and Osteocalcin in GCF sample was assessed using enzyme linked immune sorbent assay. The optical density of samples was calculated using a fully automated enzyme linked immunosorbent assay reader.&#x0D; Result: The level of Interleukin-1and Osteocalcin was always higher at the micro osteoperforation site compared to that of baseline values.&#x0D; Conclusion:A gradual increase in the levels of IL-1 and Osteocalcin was observed in both the conventional and micro osteoperforation site but statistically significant elevated levels of IL-1 and Osteocalcin were seen in micro osteoperforation site compared to conventional site.

Does puberty affect oxidative stress levels and antioxidant activity of saliva in patients with fixed orthodontic appliances?

To evaluate and compare patients' oxidative stress parameters and antioxidant status with fixed orthodontic appliances during the pubertal and postpubertal growth periods. Saliva samples of 20pubertal (mean age: 12.94 ± 0.34years) and 20postpubertal (mean age: 16.34 ± 0.45years) patients were collected just before the application of fixed orthodontic appliances (T0), 4-5 h (T1), and 7days (T2) after the initial orthodontic activation. Myeloperoxidase (MPO), nitric oxide (NO), 8‑hydroxydeoxyguanosine (8-OHdG) levels, and superoxide dismutase (SOD) activity in the saliva were examined. Repeated measures analysis of variance (ANOVA), least significant difference (LSD) pairwise comparison, and independent sample t‑tests were used to analyze the differences between the time points and growth periods, respectively. MPO levels in the saliva of patients in the pubertal period showed asignificantly higher increase within the first days of treatment (T2-T1) than in patients in the postpubertal period (p < 0.05). The SOD antioxidant enzyme activity decreased in the samples from T0 to T1 in the patients in the pubertal and postpubertal groups and returned to baseline values (T0) at T2 (p < 0.01). No significant differences in the other biochemical parameters between groups were observed. Comparing the pubertal and postpubertal groups, orthodontic force application with fixed orthodontic appliances did not change the final levels (on day7) of antioxidant status or oxidative stress markers, except for MPO in saliva.

Assessment of the Mechanical Properties of Three Commercially Available Thermoplastic Aligner Materials Used for Orthodontic Treatment

Objectives: This studied aimed to measure the yield strength and stress relaxation properties of three commercially available thermoplastic aligner materials. Methods: The three different thermoplastics aligner materials Duran (Scheu, Iserlohn, Germany), Erkodur (Pfalzgrafenweiler, Erkodent, Germany) and Track (Forestadent, Germany) were selected. A three-point bending test was carried out via the universal testing machine to measure their yield strength and stress relaxation properties. An independent t-test was performed for intergroup comparison. P-value &lt; 0.05 was set as the level of significance. Results: All the selected three polymers liberate a notable amount of stress during 24 hours. The highest stress release was observed in Duran i.e. 18.96 N/cm2 as compared to Erkodur, which was 13.96 N/cm2 and Track, which was 13.18 N/cm2. The yield strength of Duran was the highest (75.85 Mpa) compared to Track and Erkodur with the yield strength of 52.75 Mpa and 55.86 Mpa, respectively. Conclusions: Tooth movement is influenced by the composition of aligner material and its thickness. Duran had the highest stress release and yield strength. Stress released by different aligners exceeds around half of the initial stress value, which directly affects the orthodontic force application and subsequent tooth movement.

Self-attention implicit function networks for 3D dental data completion

While complete dental models are crucial for digital dentistry, current technologies mostly focus on the 3D dental crown but overlook the dental gum that is important for applications in orthodontics and prosthodontics. To reconstruct the complete dental models with visually realistic geometry from the given crown data, we propose to combine the implicit function representation with the self-attention mechanism. Recent studies have shown that the implicit function is an effective 3D representation for shape completion. However, existing methods fail in dealing with dental models with complex shapes and details, because the convolution and linear operations adopted in their networks are inefficient for modeling long-range dependencies or hard to maintain detailed geometry of the shapes. Therefore, we propose to introduce self-attention to the implicit function network for the first time and use it to effectively capture non-local features at different levels. Extensive ablation studies were conducted to validate the efficiency of our method. Quantitative and qualitative comparisons demonstrate that the feature extracted by our network is more expressive and thus leads to better dental model completion and reconstruction results.

A Review of Laser Applications in Orthodontics

Lasers have been widely used in most fields of dentistry for many years, and they have recently gained popularity in orthodontics. Its use has allowed orthodontists to overcome some of the difficulties associated with traditional orthodontic treatment procedures. These include direct chair side clinical orthodontic procedures, adjunctive orthodontic and laboratory procedures. This review article is about the applications of lasers in field of orthodontics.

3D digital analysis of tooth movement with magnets and elastics in vitro

ObjectivesMagnets have many advantages in orthodontics, and our previous studies confirmed their therapeutic potential through 3D-data analysis. The aim of this study was to compare tooth movements, including rotation, obtained via magnetic and elastic forces in crowded cases in vitro. MethodsTypodont models mimicking a crowded case were prepared. In the magnetic force-driven orthodontics (MG) group, Nd-Fe-B magnets were attached to the labial surfaces from UR4 to UL4 for attracting force, and to UR6 and UL6 for repulsing force. For the elastic force-driven orthodontic (EL) group, brackets were placed on labial surfaces from UR2 to UL2 with power-chain elastics. A NiTi archwire was used in both groups. The models were 3D scanned before and after tooth movement and exported as STL files. The pre- and post-movement STL files were superimposed. The 3D coordinates of the measurement points of the crown and root apex were obtained, and tooth displacement, 3D movements (X, Y, and Z-axis), and rotation (yaw, pitch, and roll) were calculated. Two-tailed Student's t-test was performed for comparison of the results between MG and EL groups (n = 3). ResultsOverall, both groups indicated similar movement and rotation to achieve the planned arch form. In the crown movement and rotation, no significant differences were observed between MG and EL groups. However, in the root movement, there was a significant difference between MG and EL groups in X and Z axis for the canines. ConclusionsMagnetic force-driven orthodontics demonstrated comparable results to elastics with less tipping movement, suggesting a potential future orthodontic modality. Clinical significanceThis in vitro study showed the potential of magnetic force for orthodontic application. The magnetic force-driven orthodontics might provide less tipping tooth movement compared to conventional methods, such as power chains, and could be a future technique for comprehensive orthodontic treatment.