Tablet Application Research Articles

Quantitative evaluation of Danqi tablet by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry integrated with bioassay.

Danqi tablet composed of the dried roots of Salvia miltiorrhiza and Panax notoginseng is a well-known Chinese patent medicine commonly used for the treatment of cardio-cerebrovascular diseases such as coronary heart disease and myocardial ischemia. Numerous chemical constituents belonging to S. miltiorrhiza and P. notoginseng were detectable in Danqi tablet. Here, we established and validated a rapid and sensitive ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry method for simultaneous quantification of 23 components in Danqi tablet and then successfully applied to assay 12 batches of samples from ten manufacturers. Our results demonstrated that the contents of 23 components in 12 batches of Danqi tablets varied significantly and their quality indeed existed differently based on the principal component analysis. According to the quantitative data and the loading plot of principal component analysis, five abundant compounds in Danqi tablet were selected as characteristic chemical markers possibly responsible for the quality assessment. Among them, salvianolic acid B and ginsenoside Rg1 were further chosen to be combined at 2:5 ratio to evaluate the anti-thrombotic activity on phenylhydrazine-induced zebrafish heart thrombosis model. Expectedly, this component combination increased the heart red blood cells intensity compared with the model group and the median effective concentration was 123.4µg/mL, suggestive of its well anti-thrombotic effect. This study contributed to the quantitative evaluation of Danqi tablet and indicated the combination of salvianolic acid B and ginsenoside Rg1 may be capable of reflecting the effect of Danqi tablet, thereby providing a reference for further investigations on the improvement of quality control and clinical application of Danqi tablet.

Psychometric properties of a self-assessment questionnaire concerning symptoms and impairment in urinary tract infections: the UTI-SIQ-8

ObjectivesTo validate the urinary tract infection-Symptom and Impairment Questionnaire (UTI-SIQ-8), a questionnaire that consists of four items to assess the symptom severity for dysuria, urgency, frequenc, and low abdominal pain...

An attempt of digitalization Bali Strait purse seine capture fisheries data

Similar situations with most small-scale fisheries globally, data collection remains the most highlighted issues in Bali sardine purse seine fishery. Nowadays, one of the promising approaches in fisheries data monitoring is through a technological application. This study attempts to conduct the digitalization of capture fisheries data through a tablet application development and implementation, namely MICT-L. It develops since June 2018 based on an existing paper recorder system and operated by the fishing-port officer. MICT-L was fully established in November 2018 in Muncar and September 2019 in Pengambengan fishing port, and this system has been collected and store digital landing data successfully. In addition to the initiation, a GPS-trackers system, namely TREKFISH, was installed in November 2019 and successfully collected fishing ground position data from 19 vessels until February 2020. During the study, a total of 8,248 landings in Muncar and 6,598 landings in Pengambengan were collected and stored accordingly. MICT-L and TREKFISH data successfully support the faster near real-time statistical analysis and spatial grid productivity. These two initiations are potent tools for collecting and visualizing digital catch data and fishing grounds for Bali purse seine fisheries.

Immersive virtual reality as a tool to learn problem-solving skills

Immersive virtual reality (IVR) technology has demonstrated positive educational outcomes related to its use and is gaining traction in educational and training settings; IVR is expected to have widespread adoption within the classroom in the upcoming years. However, the educational potential of IVR with children has not been thoroughly investigated, especially as a tool for problem-solving skills. Therefore, this study was designed to answer the following questions: (1) Is IVR a useful tool to learn and practice problem-solving skills? More specifically, do children using IVR solve a game better than those using a tablet application or a board game? (2) Does IVR provide a more engaging experience for children to practice problem-solving skills than on a tablet or a board game? (3) Do problem-solving skills learned with IVR technology transfer to real-life (physical game)? Children (n = 120) aged 7–9.9 years were randomly assigned to a problem-solving game in one of three conditions: board game, tablet, or IVR. The results showed that, overall, the percentage of children who completed the problem-solving game was higher in the IVR condition (77.5%), compared with those in the tablet (32.5%) or board game (30%) conditions. We also found that the interest and enjoyment scores of participants using IVR were significantly higher than participants in the other two conditions, and that the children in the IVR condition were able to learn how to solve the problem and transfer their learning to the physical game. IVR is a technology capable of engaging interest and motivating the user, as well as having the potential to assist in cognitive processing and knowledge transfer.

Digital trail making test-black and white: Normal vs MCI

Objective Trail Making Test-Black and White (TMT-B&W) was developed to assess the cognition of patients with mild cognitive impairment (MCI), dementia, and Alzheimer’s disease. Collection and analysis of test results have been limited due to scoring time and efforts required from both administrators and patients during and after taking the test. To increase efficiency and reducing scoring time, a computer version touchscreen-based digital trail making test-black and white (dTMT-B&W) was developed on Android and it was administered on MCI versus cognitively normal controls (NC) participants. The current study examines the sensitivity of newly developed computer version dTMT-B&W on NC and MCI subjects. Method dTMT-B&W was developed using MIT app inventor software, a web-based integrated development environment (IDE) with the Android development tools that are used to build fully functional applications for smartphones and tablets. A total of 44 participants were included, comprised of 22 NC and 22 MCI. The dTMT-TMT-B&W was administered to all NC and MCI subjects. Result dTMT-B&W was designed to be as consistent with the pen-paper TMT-B&W (ppTMT-B&W) where the application is a standalone installation. dTMT-B&W is divided into two parts (Part-A and Part-B), in which the subject attempts to connect black and white numbered circles sequentially as quickly as possible, while still maintaining accuracy. Similarly, the paper-based TMT-B&W requires the subject to connect black and white numbered circles in ascending order, except on a sheet of paper rather than a tablet. dTMT-B&W successfully distinguished NC from MCI subjects. Conclusion dTMT-B&W is an Android application that was successfully developed to be as consistent as possible with the original pen-paper TMT-B&W to establish equal concurrent validity, with some improved features embedded into the design and dTMT-B&W revealed a significant correlation with frontal executive function and this can help in early diagnosing subjects with MCI among NC subjects.

Near visual function measured with a novel tablet application in patients with astigmatism

ABSTRACT Clinical relevance While the clinical focus of performance metrics is traditionally based on visual acuity, research from the field of visual impairment has demonstrated that metrics such as reading speed and critical print size correlate much more strongly with subjective patient reported outcomes and assessed ability in real‐world tasks. Background More recently, digital device use has increasingly replaced many paper‐based tasks. Therefore, this study aimed to assess the correlation between standard acuity/contrast metrics and functional reading ability compared to real‐world performance on an iPad‐based reading task with astigmatic patients corrected wearing toric and mean spherical equivalent contact lenses. Methods Thirty‐four adult participants, with −0.75 to −1.50-D of refractive astigmatism, were enrolled in a double‐masked cross‐over study and fitted with toric and spherical equivalent contact lenses, in random order. A digital application was developed to assess zoom, contrast modifications, the distance at which the tablet was held, blink rate, and time to complete the reading task. High and low contrast near logMAR visual acuity were measured along with reading performance (critical print size and optimal reading speed). Results The amount participants chose to increase tablet font size (zoom) was correlated with their high‐contrast visual acuity with toric correction (r = 0.434, p = 0.010). With best sphere correction, zoom was associated with reading speed (r = −0.450, p = 0.008) and working distance (r = 0.522, p = 0.002). Text zoom was also associated with horizontal (toric: r = 0.898, p < 0.001; sphere: r = 0.880, p < 0.001) and vertical scrolling (toric: r = 0.857, p < 0.001; sphere: r = 0.846, p < 0.001). There was a significant negative association between the selection of text contrast and zoom (toric: r = −0.417, p = 0.0141; sphere: r = −0.385, p = 0.025). Conclusion Real‐world task performance allows more robust assessment of visual function than standard visual metrics alone. Digital technology offers the opportunity to better understand the impact of different vision correction options on real‐world task performance.

Evolution of fetal cardiac imaging in 30 years of ISUOG.

Evolution of fetal cardiac imaging in 30 years of ISUOG.

Use of the Graphic Tablet in the Art and Educational University

This article is discussing application of graphic tablet in the art educational University, by introducing it in design and work with graphical images related to the creation and editing of raster, vector graphics. Sequential drawing of the simplest elements for training the hand’s muscle memory achieved during classes by use of the pen and graphic tablet. The relevance in the application of this device opens up new opportunities in art education when using modern graphic technologies. The main findings observed at the end of the class, where students familiarized themselves with the principles of connection and using the technique of pen (stylus) on the graphics tablet. Students mastered the techniques of drawing from the simplest elements to more complex tasks. The article discusses the practical use of a graphics tablet in modern art education in the context of distant learning.

ImplantoPUC: an educational application for mobile computing devices aimed at patients and professionals in the field of Implantology

ABSTRACT Objective: development of an application for mobile computer devices, mobile phones and tablets, which contains educational material for patients and professionals in the area of Implantology. The use of ImplantoPUC at PUC Minas implant dentistry clinics aims at a more effective communication between professionals and patients, with better visualization of the proposed treatments, improving the understanding of patients. Methods: for the development of ImplantoPUC, a responsive technology was used, and the application windows can adapt to different screen formats, consequently, the application can be made available on different platforms such as: Web, Android and Apple. The application size is 13.4 MB and was developed using the OutSystems platform using Apache Cordova. The prototype of the ImplantoPUC application can already be accessed through the link https://includesistemas.outsystemcloud.com/implantpuc/homescreen. Results: the application is still under test at PUC Minas implant dentistry clinics, but due to the pandemic its use is still below expectations. In the Play Store your rating has a maximum rating of 5.0, with more than 50 downloads so far. Conclusion: Implanto PUC makes the task of informing more interactive and easy to understand for patients, also assisting professionals in the area in obtaining updated information and at the reach of hands, and can also be used in other Dentistry Educational Institutions, becoming a reference in the area of implant dentistry.

Scalable flibanserin nanocrystal-based novel sublingual platform for female hypoactive sexual desire disorder: engineering, optimization adopting the desirability function approach and in vivo pharmacokinetic study

Flibanserin (FLB) was approved by FDA for the treatment of pre-menopausal female hypoactive sexual desire disorder (HSDD). FLB suffers from low oral bioavailability (33%) which might be due to hepatic first-pass metabolism in addition to its poor aqueous solubility. The sublingual route could be a promising alternative for FLB due to the avoidance of enterohepatic circulation. However, the drug needs to dissolve in the small volume of saliva in order to be absorbed through the sublingual mucosa. Therefore, FLB nanocrystals were prepared by sono-precipitation technique according to 23 full factorial design. FLB-nanocrystals were formulated using two surfactants (PVP K30 and PL F127) in two different amounts (200 and 400 mg) and the volume of ethanol was either 3 or 5 mL. Nanocrystal formulation was optimized according to the desirability function to have a minimum particle size, zeta potential, polydispersity index, and maximum saturated solubility. The optimized formula had a particle size of 443.12 ± 14.91 nm and a saturated solubility of 23.27 ± 4.62 mg/L which is five times the saturated solubility of FLB. Nanocrystal dispersion of the optimized formula was solidified by freeze-drying and used to prepare rapidly disintegrating sublingual tablets containing Pharmaburst® as superdisintegrant. Sublingual tablet formulation with the shortest disintegration time (36 s) was selected for the in vivo study. FLB nanocrystal-based sublingual tablets exhibited a two-fold increase in bioavailability with a faster onset of action compared to the commercially available oral formulation. These findings prove the potential application of FLB nanocrystal-based sublingual tablets in the treatment of HSDD.

A High-Realism and Cost-Effective Training Simulator for Extracorporeal Membrane Oxygenation

Medical simulators, employed in extracorporeal membrane oxygenation (ECMO), are burdened with costly equipment and low-fidelity methodologies. This dichotomy necessitated a new approach that eliminates high-costs and integrates with the critical care environment. This is especially applicable after the Coronavirus pandemic, where resources and supplies are evermore scarce. After examining the state-of-the-art and establishing a close collaboration with Hamad Medical Corporation (HMC), the main healthcare provider in Qatar, several criteria were identified to advance the cutting-edge. In this article, a high-realism, cost-effective ECMO simulator is presented. It runs on a novel blood simulation technology along with simulation modules. An instructor tablet application enables instructors to orchestrate the training experience wirelessly with real-time performance. It also includes a novel scenario designer for implementing consistent simulation curricula. A product-level simulator with high-fidelity casings is in the final integration phases. Current results include developing and testing the simulated blood circuit, simulation modules for hemorrhaging, line chattering, air bubbles noise, and a replicated console along with an integrated communications system. Nineteen specialists rated the fidelity of the system as highly realistic during a questionnaire-based study. It is expected to run a second study to evaluate the educational efficacy of the simulator as a first-of-its-kind in the region.

Development of a tablet application to promote effective training for standardized patients

Development of a tablet application to promote effective training for standardized patients

Українськомовні аудіокниги: види, функції, асортимент, переваги й недоліки

У статті проаналізовано історію виникнення і розвиток в Україні звукових (аудіо) книг від записів на платівках до цифрових форматів MP3. Хоча дослідники вважають, що на сьогодні ринок аудіокниг в Україні малорозвинений, в українському інформаційному просторі цей вид видань набуває все більшої популярності, кількість виробників і ресурсів з аудіокнигами українською мовою зростає, жанровий і тематичний асортимент розширюється. Самі ж звукові книги відіграють подвійну роль (є окремим видом видання і водночас способом популяризації літератури), а також виконують низку функцій: просвітницьку, навчальну, розважальну і є основним видом книг для людей із вадами зору.Також авторка статті на основі проведеного дослідження пропонує власну класифікацію аудіокниг і виокремлює їх види за різними критеріями: за кількістю читців (книга, начитана одним диктором; радіовистава – читання в особах, рольова гра), за обсягом тексту твору (повні аудіоверсії; скорочені аудіокниги), за професійним рівнем того, хто виготовив аудіокнигу (професійний запис; авторське читання; аматорський запис; автоматичне озвучування), за матеріальним носієм і форматом (книги на платівках; книги на магнітних плівках; цифрові книги), за ступенем аранжування (з аранжуванням; без аранжування).У статті проаналізовано контент ресурсів з аудіокнигами українською мовою і продукцію провідних виробників звукових книг в Україні: компанії-виробники аудіокниг початку ХХІ ст. (ТОВ «Українська аудіокнига», компанія «А.Е.Л.», «Книга вголос», «Сорока Білобока», «Студія Слово», «Атлантік», «Аудіо Планета» та інші), портал «Гуртом – Торрент-Толока», проєкти Українського радіо, онлайн-бібліотеки, інтернет-магазини, додатки для смартфонів і планшетів, YouTube-канали, кількість підписників яких є стабільно високою й постійно збільшується.Також ідеться про переваги й недоліки звукових форматів книг на основі відгуків виробників, письменників, літературних критиків і власних спостережень авторки щодо створення і споживання аудіоверсій літературних творів.

Collecting big data with small screens: Group tests of children\u2019s cognition with touchscreen tablets are reliable and valid

Collecting experimental cognitive data with young children usually requires undertaking one-on-one assessments, which can be both expensive and time-consuming. In addition, there is increasing acknowledgement of the importance of collecting larger samples for improving statistical power Button et al. (Nature Reviews Neuroscience 14(5), 365–376, 2013), and reproducing exploratory findings Open Science Collaboration (Science, 349(6251), aac4716–aac4716 2015). One way both of these goals can be achieved more easily, even with a small team of researchers, is to utilize group testing. In this paper, we evaluate the results from a novel tablet application developed for the Resilience in Education and Development (RED) Study. The RED-app includes 12 cognitive tasks designed for groups of children aged 7 to 13 to independently complete during a 1-h school lesson. The quality of the data collected was high despite the lack of one-on-one engagement with participants. Most outcomes from the tablet showed moderate or high reliability, estimated using internal consistency metrics. Tablet-measured cognitive abilities also explained more than 50% of variance in teacher-rated academic achievement. Overall, the results suggest that tablet-based, group cognitive assessments of children are an efficient, reliable, and valid method of collecting the large datasets that modern psychology requires. We have open-sourced the scripts and materials used to make the application, so that they can be adapted and used by others.

Components of a risk assessment tool for prevention and control of bovine respiratory disease in preweaned dairy calves.

Bovine respiratory disease (BRD) is the leading natural cause of death in US beef and dairy cattle, causing the annual loss of more than 1 million animals and financial losses in excess of $700 million. The multiple etiologies of BRD and its complex web of risk factors necessitate a herd-specific intervention plan for its prevention and control on dairies. Hence, a risk assessment is an important tool that producers and veterinarians can utilize for a comprehensive assessment of the management and host factors that predispose calves to BRD. The current study identifies the steps taken to develop the first BRD risk assessment tool and its components, namely the BRD risk factor questionnaire, the BRD scoring system, and a herd-specific BRD control and prevention plan. The risk factor questionnaire was designed to inquire on aspects of calf-rearing including management practices that affect calf health generally, and BRD specifically. The risk scores associated with each risk factor investigated in the questionnaire were estimated based on data from two observational studies. Producers can also estimate the prevalence of BRD in their calf herds using a smart phone or tablet application that facilitates selection of a true random sample of calves for scoring using the California BRD scoring system. Based on the risk factors identified, producers and herd veterinarians can then decide the management changes needed to mitigate the calf herd's risk for BRD. A follow-up risk assessment after a duration of time sufficient for exposure of a new cohort of calves to the management changes introduced in response to the risk assessment is recommended to monitor the prevalence of BRD.

But will they use it? Factors influencing sustained use of a digital memory notebook application by individuals with mild cognitive impairment

AbstractBackgroundAdvances in technology have fueled new opportunities to improve external compensatory devices. The Digital Memory Notebook (DMN) is an iOS tablet application (app) developed in collaboration with older individuals with mild cognitive impairment (MCI) to support functional independence. To understand users for whom DMN training was beneficial, we examined data from a pilot clinical trial for factors that influenced sustained use of this compensatory tool.MethodTwenty‐five participants (M age = 72; M education = 16; 48% female) with MCI learned to use the DMN app in 5‐6 (two‐hour) training sessions delivered within one‐month. Participant use of the DMN app was then monitored through real‐time collection of data usage metrics for an additional three months. Based on app use during the third‐month post‐training, participants were divided into DMN user (N = 13; M daily distinct uses = 4.5) and non‐user (N = 12) groups. Demographics, clinician ratings, baseline clinical measures and DMN usage metrics were all examined.ResultNo group differences emerged in demographics, pre‐morbid ability estimate (High Average), or clinician ratings of motivation, comprehension, insight and competency during training sessions. DMN non‐users exhibited lower scores on standardized measures of global cognitive status (Low Average vs. Average) and memory (Borderline vs. Low Average), and self‐reported poorer everyday memory. DMN usage metrics captured during training revealed no group differences in week one (sessions 1‐2). By week two (session 3), DMN non‐users showed fewer daily distinct uses of the DMN (4 vs. 8). During weeks 3 and 4, DMN non‐users continued to show fewer daily distinct uses as well as fewer interactions with all sections of the app (i.e., calendar, daily event scheduling, notes and journal). Non‐users also demonstrated poorer use of advanced app functions during training (e.g., high priority scheduling, reminder alarms, picture use, prospective memory use).ConclusionIndividuals with MCI who were actively using the DMN three‐months post‐intervention were less cognitively impaired, demonstrated greater DMN use as early as week two of training, and made use of advanced functions. Next steps include increasing DMN use through early adaptive learning and continued automated booster training.

App-based learning for kindergarten children at home (Learning4Kids): study protocol for cohort 1 and the kindergarten assessments

BackgroundChildren’s literacy and mathematical competencies are a critical platform for their successful functioning as individuals in society. However, many children, in particular those with low socio-economic status (SES) backgrounds who may not receive the home support needed to develop to their full potential, are at risk of not reaching sufficient competence levels. The overall aim of this project is to develop innovative computer tablet applications (‘apps’) and test whether the apps support parents in the provision of high-quality home learning environments (HLEs) and impact positively on the short- and long-term development of children’s competencies.Altogether, “App-based learning for kindergarten children at home” (Learning4Kids) is a 5-year longitudinal study funded by the EU and designed to assess the potential impact of a tablet-based family intervention on children’s learning, development, social inclusion and well-being.Methods/designThis study uses a multi-method intervention approach and draws on expertise from psychology, education, informatics, and didactics to evaluate the effectiveness of learning apps and the intervention approach. It also exploits new technological possibilities afforded by tablet computers that are very common nowadays in families. Learning4Kids sets out to measure the quality of the HLE, children’s early mathematical, literacy, and cognitive competencies and their behaviour. Here, data will be gathered via standardized tests, observations, and parental and educator surveys and checklists. Data collection also includes the assessment of app usage times via mobile sensing. In cohort 1, 190 families are assigned to one of four groups. One business-as-usual group will only participate in the child assessments, whereas the three remaining groups are provided with tablets for about 10 months. Two intervention groups will receive mathematical or literacy learning apps as well as parental information about these topics and the tablet-control-group will receive similar apps and information that focus on general child development, but not on mathematics or literacy.DiscussionWhilst offering substantive advances for the scientific fields of psychology and education, the Learning4Kids study also has broad societal implications. Improving young children’s learning trajectories is both a social and economic imperative as it equips them to achieve greater individual success and to contribute to societal prosperity.

CARE: Context-awareness for elderly care

We present CARE, a context-aware tool for nurses in nursing homes. The system utilises a sensors infrastructure to quantify the behaviour and wellbeing (e.g., activity, mood, social and nurse interactions) of elderly residents. The sensor data is offloaded, processed and analysed in the cloud, to generate daily and long-term summaries of residents’ health. These insights are then presented to nurses via an Android tablet application. We aim to create a tool that can assist nurses and increase their awareness to residents’ needs. We deployed CARE in a local nursing home for two months and evaluated the system through a post-hoc exploratory analysis and interviews with the nurses. The results indicate that CARE can reveal essential insights on the wellbeing of elderly residents and improve the care service. In the discussion, we reflect on our understanding and potential impact of future integrated technology in elderly care environments.

Integrating a Machine Learning System Into Clinical Workflows: Qualitative Study.

BackgroundMachine learning models have the potential to improve diagnostic accuracy and management of acute conditions. Despite growing efforts to evaluate and validate such models, little is known about how to best translate and implement these products as part of routine clinical care.ObjectiveThis study aims to explore the factors influencing the integration of a machine learning sepsis early warning system (Sepsis Watch) into clinical workflows.MethodsWe conducted semistructured interviews with 15 frontline emergency department physicians and rapid response team nurses who participated in the Sepsis Watch quality improvement initiative. Interviews were audio recorded and transcribed. We used a modified grounded theory approach to identify key themes and analyze qualitative data.ResultsA total of 3 dominant themes emerged: perceived utility and trust, implementation of Sepsis Watch processes, and workforce considerations. Participants described their unfamiliarity with machine learning models. As a result, clinician trust was influenced by the perceived accuracy and utility of the model from personal program experience. Implementation of Sepsis Watch was facilitated by the easy-to-use tablet application and communication strategies that were developed by nurses to share model outputs with physicians. Barriers included the flow of information among clinicians and gaps in knowledge about the model itself and broader workflow processes.ConclusionsThis study generated insights into how frontline clinicians perceived machine learning models and the barriers to integrating them into clinical workflows. These findings can inform future efforts to implement machine learning interventions in real-world settings and maximize the adoption of these interventions.

Tablet or Paper and Pen? Examining Mode Effects on German Elementary School Students’ Computation Skills with Curriculum-Based Measurements

&lt;p style="text-align:justify"&gt;Progress monitoring of academic achievement is an essential element to prevent learning disorders. A prominent approach is curriculum-based measurement (CBM). Various studies have documented positive effects of CBM on students’ achievement. Nevertheless, the use of CBM is associated with additional work for teachers. The use of tablets may be of help here. Yet, although many advantages of computer- or tablet-based assessments are being discussed in the literature (e. g. innovative item formats, adaptive testing, automated scoring and feedback), there are still concerns regarding the comparability of different assessment modes (paper-pencil vs. tablet). In the study presented, we analyze the CBM data of 98 fourth graders. They processed the exact same computation items once with paper and pen and once in a tablet application. The analyses point to comparable results in the test modes, although some significant deviations can be found at item level. In addition, the children report perceived benefits when working with the tablet.&lt;/p&gt;