Application Of 3D Printing Technology Research Articles

Experimental study on buildability and mechanical properties of 3D printing cob

The application of 3D printing technology to earth buildings conforms to the development concept of low carbon, green and intelligent construction. The key issue lies in the development of earth material with both favorable buildability and sufficient mechanical properties. In this study, the printing parameters of mixture for 3D printing with different water contents were optimized. The optimum water content of 3D printing cob was determined based on the buildability. The result shows that when the flow spreading diameter is between 140 mm and 160 mm, 3D printing cob has good buildability performance. The optimum water content is 24.6 %. In addition, anisotropic performance was analyzed by compressive strength tests from three orthogonal directions. In particular, according to the test results of single printing limit height and yield stress, the buildability of 3D printing cob wall was analyzed. The building strategy of the printing divided into multiple times was obtained.

Evaluating the Educational Impact of 3D-Printed Toys in Elementary Settings: A Mixed-Methods Study

This study explores the impact of integrating the use of disruptive technologies on 3D-printed toys within elementary education through a mixed-methods approach, combining an experimental design with qualitative interviews. Focusing on the potential of disruptive technologies to innovate educational practices, we divided participants into control and experimental groups, the latter engaging with the 3D-printed educational toys. Despite the innovative application of 3D printing technology in educational settings, our findings reveal no significant differences in the learning outcomes between the two groups. Therefore, this research contributes to the literature on educational innovation, suggesting that the mere introduction of novel technologies, such as 3D printing, may not be sufficient to enhance learning effectiveness. Regarding practical implications, the study is aimed at scholars, teachers, and educational managers, to underscore the necessity of a critical assessment of educational tools and calls for further investigation into how technology integrates into pedagogical frameworks to truly benefit elementary education. Received: 12 July 2024 / Accepted: 31 October 2024 / Published: 05 November 2024

Application of 3D Printing Technology in Microreactor Fabrication

Application of 3D Printing Technology in Microreactor Fabrication

3-Dimensional Printing in Healthcare: Manufacturing Techniques and Applications

3D printing and additive manufacturing are interchangeable terms. Additive manufacturing builds models layer by layer using a variety of laser-based or sophisticated printing processes. While this was one of the earliest techniques for 3D printing, the field now widely uses a number of other patented methods. The objective is to analyze the success rate of 3D printing in healthcare. The medical industry has found 3D printing to be highly beneficial in recent years. The application of 3D printing technology allows for greater customization of the therapeutic process, which enhances treatment safety, accuracy, and precision. On the other hand, the disclosure of new materials for 3D printing occurs frequently. For some producers, the right materials might just be a few months or years away. However, printing certain materials may be difficult or impossible. Excellent results are not always possible with 3D printers. We can conclude that 3D printing represents one of the most advanced techniques in healthcare.

Development of Mathematical Function Control-Based 3D Printed Tablets and Effect on Drug Release.

The application of 3D printing technology in drug delivery is often limited by the challenges of achieving precise control over drug release profiles. The goal of this study was to apply surface equations to construct 3D printed tablet models, adjust the functional parameters to obtain multiple tablet models and to correlate the model parameters with the in vitro drug release behavior. This study reports the development of 3D-printed tablets using surface geometries controlled by mathematical functions to modulate drug release. Utilizing fused deposition modeling (FDM) coupled with hot-melt extrusion (HME) technology, personalized drug delivery systems were produced using thermoplastic polymers. Different tablet shapes (T1-T5) were produced by varying the depth of the parabolic surface (b = 4, 2, 0, -2, -4mm) to assess the impact of surface curvature on drug dissolution. The T5 formulation, with the greatest surface curvature, demonstrated the fastest drug release, achieving complete release within 4h. In contrast, T1 and T2 tablets exhibited a slower release over approximately 6h. The correlation between surface area and drug release rate was confirmed, supporting the predictions of the Noyes-Whitney equation. Differential Scanning Calorimetry (DSC) and Scanning Electron Microscope (SEM) analyses verified the uniform dispersion of acetaminophen and the consistency of the internal structures, respectively. The precise control of tablet surface geometry effectively tailored drug release profiles, enhancing patient compliance and treatment efficacy. This novel approach offers significant advancements in personalized medicine by providing a highly reproducible and adaptable platform for optimizing drug delivery.

Optimizing Low-Cost Gas Analysis with a 3D Printed Column and MiCS-6814 Sensor for Volatile Compound Detection.

This paper explores an application of 3D printing technology on the food industry. Since its inception in the 1980s, 3D printing has experienced a huge rise in popularity. This study uses cost-effective, flexible, and sustainable components that enable specific features of certain gas chromatography. This study aims to optimize the process of gas detection using a 3D printed separation column and the MiCS-6814 sensor. The principle of the entire device is based on the idea of utilizing a simple capillary chromatographic column manufactured by 3D printing for the separation of samples into components prior to their measurement using inexpensive chemiresistive sensors. An optimization of a system with a 3D printed PLA block containing a capillary, a mixing chamber, and a measuring chamber with a MiCS-6814 sensor was performed. The optimization distributed the sensor output signal in the time domain so that it was possible to distinguish the peak for the two most common alcohols, ethanol and methanol. The paper further describes some optimization types and their possibilities.

Revolutionizing Transdermal Patches: Navigating Clinical Challenges and Technological Progress

ransdermal patches, conceived to extend drug release, enhance bioavailability, and foster patient adherence, witnessed their inaugural approval by the USFDA in the 1980s. These patches, varying in size, constitute medicinal formulations with one or more active components that permeate the bloodstream through the skin. This review undertakes a comprehensive examination of recent strides in transdermal patch technology, encompassing critical facets such as their merits and demerits, advancements in microneedle technology, the evolution of transdermal patch generation, the integration of Artificial Intelligence, and the role of 3D printing technology. Additionally, the focus is placed on USFDA-approved patches. Various literature databases viz. Science Direct, PubMed, and Web of Sciences were explored for this research. The review furnished insights into the application of 3D printing technology in the fabrication of transdermal patches and disseminated information on USFDA-approved patches. The exploration delved into diverse strategies aimed at augmenting the efficiency of drug delivery and promoting patient compliance. Major transdermal products being marketed with details of their active substance have been discussed. Various applications of artificial intelligence in drug delivery have been summarized. It may be summarized that transdermal patch technology is not a thing of the past but a technology to stay and meet the demands of drug delivery in the present and future.

Application of 3D Printing Technology in Furniture Construction.

In recent years, 3D printing technology has become very important in many fields of science, manufacturing, design, medicine, aviation, sports, etc. Furniture design and manufacturing are also not left out of this trend. In this study, the results of bending moments and stiffness of joints of thin structural elements connected by 3D printing with polylactic acid (PLA) connectors are given. The connectors are newly developed, and information on their strength characteristics is lacking in the literature. Ten joints were investigated, made with 9 and 12 mm plywood and 6 mm MDF. The tested joints constructed by 3D-printed connecting elements show a high strength under arm compression bending load, between 44.16 and 24.02 N·m. The stiffness coefficients of joints with 3D-printed connecting elements are between 348 and 145 N·m/rad and are higher than those of conventional detachable mitre joints but lower than those of glued ones. The type of filling of the hollow section of the connecting elements and the wall thickness influenced the joints' strength and stiffness. Reducing the width of the connecting elements from 40 to 30 mm and the inner radius between the arms from 2 to 1 mm does not significantly affect the joints' strength and stiffness coefficients.

Application of 3D printing technology in micro chemical engineering

Application of 3D printing technology in micro chemical engineering

Recent Developments and Applications of 3D-Printing Technology in Pharmaceutical Drug Delivery Systems: A New Research Direction and Future Trends.

The advent of 3D printing technology has emerged as a key technical revolution in recent years, enabling the development and production of innovative medication delivery methods in the pharmaceutical sector. The designs, concepts, techniques, key challenges, and potential benefits during 3D-printing technology are the key points discussed in this review. This technology primarily enables rapid, safe, and low-cost development of pharmaceutical formulations during the conventional and additive manufacturing processes. This phenomenon has wide-ranging implications in current as well as future medicinal developments. Advanced technologies such as Ink-Jet printing, drop-on-demand printing, Zip dose, Electrohydrodynamic Printing (Ejet) etc., are the current focus of the drug delivery systems for enhancing patient convenience and improving medication compliance. The current and future applications of various software, such as CAD software, and regulatory aspects in 3D and 4D printing technology are discussed briefly in this article. With respect to the prospective trajectory of 3D and 4D printing, it is probable that the newly developed methods will be predominantly utilized in pharmacies and hospitals to accommodate the unique requirements of individuals or niche groups. As a result, it is imperative that these technologies continue to advance and be improved in comparison to 2D printing in order to surmount the aforementioned regulatory and technical obstacles, render them applicable to a vast array of drug delivery systems, and increase their acceptability among patients of every generation.

Thiol-functionalized MOF modified 3D printed monolithic microextraction array for analysis of trace Cd and Pb in human urine

Controlling the position, size, and shape of pores is a limitation of traditional monolithic preparation methods. The application of 3D printing technology offers high customizability, allowing the precise printing of pore positions, sizes, and shapes according to the designer's 3D model. Herein, by using Projection Microstereolithography (PμSL), we prepared a 3D-printed monolithic array with post-modification of thiol-functionalized metal-organic framework (MOF), and combined it with inductively coupled plasma mass spectrometry (ICP-MS) for the online analysis of trace Cd and Pb in human urine. To achieve array monolithic microextraction, six 3D-printed monolithic columns were modified with thiol-functionalized MOF-808 (MOF-808-SH), and were then assembled in the 3D printed extraction device incorporating gas valve and scaffold. The MOF-808-SH modified 3D-printed monolithic column exhibits excellent extraction performance to Cd2+ and Pb2+ due to rich active adsorption sites and hierarchical porous structure, and has long life span (>100 reused times). Under the optimized conditions, the limits of detection (LODs) are 3.5 and 17.6 ng L−1 for Cd2+ and Pb2+, respectively, with the relative standard deviations of 4.9 % and 8.2 % (0.1 μg L−1, n = 7), and the sample throughput is 11 h−1. To validate the accuracy of the method, the method was used to determine Cd and Pb in Certified Reference Materials of freeze-dried human urine, the determined results agree well with the certified values. This method was also successfully applied to the determination of trace Cd and Pb in real human urine samples. The developed method offers low LODs, robust anti-interference capability, high sample throughput, long reuse cycles, and automation analysis, showing great potential for the analysis of trace heavy metals in biological samples.

Tailoring the Thermoelectric Properties of 3D-Printed n-Type Bi1.7Sb0.3Te3 with Incorporated Edge-Oxidized Graphene.

Using three-dimensional (3D) printing technology to fabricate Bi2Te3-based thermoelectric (TE) generators opens a potential way to create shape-conformable devices capable of recovering waste heat from thermal energy sources with diverse surface morphologies. However, pores formed in 3D-printed Bi2Te3-based materials by the removal of the organic ink binder result in unsatisfactory performance compared to the bulk materials, which has limited the widespread application of the ink-based 3D printing process. Furthermore, managing the volatile Se element in the n-type materials poses significant technological challenges compared to the p-type counterparts, resulting in a scarcity of research on 3D printing of n-type Bi2Te3. Here, we synthesized edge-oxidized graphene (EOG)-incorporated Se-free n-type Bi1.7Sb0.3Te3 (BST) using a direct ink writing (DIW) process with a binder-free novel ink. The incorporated EOG provides connectivity between small BST grains separated by pores and induces a bimodal-like grain structure during the DIW and sintering process. The optimal EOG content of 0.1 wt % in 3D-printed n-type BST simultaneously achieved both carrier transport control and active phonon scattering, due to its unique microstructure. A maximum ZT of 0.71 was obtained in the 0.1 wt % EOG/BST materials at 448 K, comparable to commercial bulk n-type Bi2Te3-based materials. Further, a single-element device composed of the EOG-BST material exhibited a 2-fold improvement in performance compared to pure-BST. These results open a technological route for the application of 3D printing technology for ink-based TE materials.

The Applications of 3D-Printing Technology in Prosthodontics: A Review of the Current Literature.

Prosthodontics has become increasingly popular because of its cosmetic attractiveness. 3D printing has revolutionized prosthodontics, enabling the creation of high-quality dental prostheses. It creates detailed restorations, such as crowns, bridges, implant-supported frameworks, surgical templates, dentures, and orthodontic models. In addition, it saves production time but faces challenges such as elevated expenses and the requirement for innovative materials and technologies. Thisreview gives insights into the uses of 3D printing in prosthodontics, presenting how it has significantly changed clinical practices. This article discusses different materials and techniques. Additionally, it showcases the capacity of 3D printing to improve prosthodontic practice and proposes prospects for future investigation.

A comprehensive review of the educational, clinical and rehabilitative applications of 3D printing technology in hand surgery

A comprehensive review of the educational, clinical and rehabilitative applications of 3D printing technology in hand surgery

Application of 3D printing in neurosurgical medical teaching and surgical training: Bibliometric analysis and prospects

Background: Traditional education in neurosurgery primarily relies on observation, giving residents and interns limited opportunities for clinical practice. However, the development of 3D printing has the potential to improve this situation. Based on bibliometrics, we analyze the application of 3D printing technology in neurosurgery medical education and surgical training. Methods: We searched the publications in this field in Web of Science core collection database from September 2000 to September 2023. VOS viewer, Citespace and Microsoft Office Excel were used to visually analyze and draw knowledge graphs. Results: A total of 231 articles and reviews were included. The United States is the country with the largest volume of articles and Mayo Clinic is the leading organization in this field. Partnership between countries, authors and institutions is also presented. World Neurosurgery is the journal with the highest number of publications. The top three key words by occurrence rate are “3D printing”, “surgery” and “simulation”. Conclusions: In recent years, more and more attention has been paid to the research in this field. According to bibliometric analysis, “accuracy” and “surgery simulation” are the research focuses in this field, while “augment reality” is the potential research target.

The Application of 3D Printing Technology in Yuan Blue-and-White Porcelain Art

Yuan blue-and-white porcelain, as a representative of Chinese ceramic art, is highly appreciated for its unique artistic value and cultural connotations. With the advancement of technology, the application of 3D printing technology in artistic creation has become increasingly widespread. This paper explores the specific applications of 3D printing technology in Yuan blue-and-white porcelain art, including improving the production process and promoting the complexity and innovation of designs. Through 3D printing technology, artists can accurately reproduce complex design patterns, enhancing production efficiency and quality while reducing errors associated with manual crafting. Additionally, 3D printing technology provides artists with greater design freedom, breaking the limitations of traditional manual techniques and making Yuan blue-and-white porcelain art more diverse. By analyzing specific cases, this paper demonstrates the practical effects of 3D printing technology in improving creation efficiency and quality. For instance, using 3D printing technology, artists can quickly produce multiple Yuan blue-and-white models for experimentation and adjustment, saving time and costs. For complex patterns and shapes, 3D printing technology can complete them in a short time, allowing artists to focus more on creative design. Furthermore, 3D printing technology enables high-precision repetitive production, ensuring consistency in quality and appearance of each piece. In the future, as 3D printing technology continues to develop, its application in Yuan blue-and-white porcelain art will become more extensive and in-depth, bringing more innovation and development opportunities to this traditional art form.

Research trends of bone tumor treatment with 3D printing technology from 2013 to 2022: a bibliometric analysis

ObjectiveBibliometrics was employed in this study to determine the research trends in the worldwide application of 3D printing technology to treat bone tumors over the previous 10 years.MethodsPublished from 2013 to 2022, the papers related to bone tumors treated with 3D printing were located in Web of Science Core Collection (WoSCC), PubMed, and Scopus. The screened articles were included in this bibliometric study. From these papers in WoSCC, information on annual publications, journals, keywords, countries, authors, institutions, and cited references were extracted and visualized with CiteSpace (version 6.1.R6) software to investigate the state of bone tumor treatment using 3D printing as well as research hotspots. The Carrot2 online visualization tool and Vosviewer software (version 1.6.20) were employed to visualize the publications from PubMed and Scopus, respectively, in order to ascertain the most popular research topics from both databases.ResultsA total of 606, 233, and 364 publications were obtained from WoSCC, PubMed, and Scopus, respectively, between the years 2013 and 2022. In WoSCC, the peak number of publications was found in 2021, with 145 publications published. Acta Biomaterialia (11 publications) and World Neurosurgery (10 publications) were the most prolific journals, and Biomaterials was the journal cited the most (244 times). Yong Zhou was the most productive author with 14 publications, while Kwok-Chuen Wong (69 citations) and William F Enneking, (69 citations) possessed the most citations. The country with the largest quantity of publications was China (207). Among all institutions, Shanghai Jiao Tong University produced the most publications (29). Rapid prototyping was the keyword with the strongest citation burst (4.73). ‘Reconstruction’, ‘surgery’, ‘resection’, and ‘design’ caught the significant attention of researchers. 3D-printed materials, pelvic reconstruction, mandibular reconstruction, computer-assisted surgical techniques, photothermal therapy, and in vitro experiments were recognized as hot subjects and trends in current research. The most frequently occurring topics in Scopus are not significantly different from those found in WoSCC. The most prevalent research areas in PubMed encompass implant, patient-specific, bioceramic, models, and pelvic.

Architectural design and optimization of internal structures in 3D printed electrodes for superior supercapacitor performance

The architecture of electrodes plays a pivotal role in the transfer and transportation of charges during electrochemical reactions. Selecting optimal electrode materials and devising well-conceived electrode structures can substantially enhance the electrochemical performance of devices. This manuscript leverages 3D printing technology to fabricate asymmetric supercapacitor devices featuring regular layered configurations. By investigating the impact of various materials on the internal architecture of printed electrodes, we establish a stratified electrode structure with an orderly arrangement, thereby significantly improving asymmetric charge transfer between electrodes. The application of 3D printing technology to construct electrode structures effectively mitigates the agglomeration of electrode materials. The 3D-printed VCG//MXene devices demonstrate exceptional areal capacitance (205.57 mF cm−2) and energy density (60.03 μWh cm−2), with a power density of 0.174 W cm−2. Consequently, selecting appropriate materials for fabricating printable electrode structures and achieving efficient 3D printing is anticipated to offer novel insights into the construction and enhancement of miniature asymmetric micro-supercapacitor (MSCs) devices.

3D-printed gradient scaffolds for osteochondral defects: Current status and perspectives.

Articular osteochondral defects are quite common in clinical practice, and tissue engineering techniques can offer a promising therapeutic option to address this issue.The articular osteochondral unit comprises hyaline cartilage, calcified cartilage zone (CCZ), and subchondral bone.As the interface layer of articular cartilage and bone, the CCZ plays an essentialpart in stress transmission and microenvironmental regulation.Osteochondral scaffolds with the interface structure for defect repair are the future direction of tissue engineering. Three-dimensional (3D) printing has the advantages of speed, precision, and personalized customization, which can satisfy the requirements of irregular geometry, differentiated composition, and multilayered structure of articular osteochondral scaffolds with boundary layer structure. This paper summarizes the anatomy, physiology, pathology, and restoration mechanisms of the articular osteochondral unit, and reviews the necessity for a boundary layer structure in osteochondral tissue engineering scaffolds and the strategy for constructing the scaffolds using 3D printing. In the future, we should not only strengthen the basic research on osteochondral structural units, but also actively explore the application of 3D printing technology in osteochondral tissue engineering. This will enable better functional and structural bionics of the scaffold, which ultimately improve the repair of osteochondral defects caused by various diseases.

Systematic Review on the Use of 3D-Printed Models for Planning, Training and Simulation in Vascular Surgery.

The use of 3D-printed models in simulation-based training and planning for vascular surgery is gaining interest. This study aims to provide an overview of the current applications of 3D-printing technologies in vascular surgery. We performed a systematic review by searching four databases: PubMed, Web of Science, Scopus, and Cochrane Library (last search: 1 March 2024). We included studies considering the treatment of vascular stenotic/occlusive or aneurysmal diseases. We included papers that reported the outcome of applications of 3D-printed models, excluding case reports or very limited case series (≤5 printed models or tests/simulations). Finally, 22 studies were included and analyzed. Computed tomography angiography (CTA) was the primary diagnostic method used to obtain the images serving as the basis for generating the 3D-printed models. Processing the CTA data involved the use of medical imaging software; 3DSlicer (Brigham and Women's Hospital, Harvard University, Boston, MA), ITK-Snap, and Mimics (Materialise NV, Leuven, Belgium) were the most frequently used. Autodesk Meshmixer (San Francisco, CA, USA) and 3-matic (Materialise NV, Leuven, Belgium) were the most frequently employed mesh-editing software during the post-processing phase. PolyJet™, fused deposition modeling (FDM), and stereolithography (SLA) were the most frequently employed 3D-printing technologies. Planning and training with 3D-printed models seem to enhance physicians' confidence and performance levels by up to 40% and lead to a reduction in the procedure time and contrast volume usage to varying extents.