Anxiety Sensitivity Research Articles

Predictors of National Institute on Alcohol Abuse and Alcoholism (NIAAA) Alcohol Recovery among Individuals in Alcohol Treatment: Implications for Social Work.

The National Institute on Alcohol Abuse and Alcoholism's (NIAAA) definition of alcohol use disorder (AUD) recovery stipulates two criteria: remission from DSM-5 AUD and cessation of heavy drinking. Importantly, these criteria allow for consideration of nonabstinent alcohol treatment outcomes. However, researchers have yet to assess potential predictors of the NIAAA recovery outcome. The current study examined associations between mental health and coping predictors of NIAAA recovery status in an AUD treatment sample. At baseline (BL) and end-of-treatment (EOT) research interviews in a clinical trial, participants (N = 118) completed questionnaires assessing alcohol dependence, mental health, and confidence levels in reducing heavy drinking, as well as alcohol use and DSM-5 AUD symptom endorsement. Logistic regression models tested the associations between chosen predictors and the odds of achieving NIAAA recovery. Twenty-four percent of individuals (n = 28) met both criteria for NIAAA recovery at EOT. Higher levels of BL state anxiety and anxiety sensitivity predicted lower odds of achieving NIAAA recovery, while greater confidence to reduce heavy drinking predicted increased odds of NIAAA recovery. Social workers are encouraged to continue assessing and addressing mental health in AUD treatment to help individuals with alcohol problems achieve their AUD recovery goals.

Understanding the role of cannabis use on cigarette dependence severity among individuals with e-cigarette and combustible tobacco dual use.

The use of both electronic and combustible cigarettes is related to greater rates of cannabis use. Further, cannabis use is associated with worse combustible smoking-related outcomes, yet little research has identified mechanisms underlying such relations. It may be that negative-affect-related transdiagnostic factors such as emotion dysregulation, anxiety sensitivity, and/or distress intolerance play a mechanistic role in the cannabis-tobacco interrelations. The current study tested this hypothesis among 400 adults who endorsed dual use, 33% of whom endorsed current (past 3 months) cannabis use. We conducted analyses of variance and indirect effects model using the PROCESS v4.1 macro in SPSS version 29. Results indicated that participants who use cannabis reported greater difficulty with emotion regulation, anxiety sensitivity, and cigarette dependence severity. Cannabis use was related to cigarette dependence severity indirectly via difficulty with emotion regulation and anxiety sensitivity. These results indicate that specific transdiagnostic negative-affect-related factors of difficulty with emotion regulation and anxiety sensitivity are associated with cannabis use among adults who smoke combustible and electronic cigarettes. Given that these transdiagnostic factors are malleable, these findings suggest targeting and engaging such mechanisms may offer novel behavioral change strategies for this high-risk population.

Anxiety sensitivity in relation to smoking dependence motives among Latinx persons who smoke.

Hispanic/Latinx (hereafter Latinx) persons are an established tobacco disparities population in the United States (US). Past work has suggested that individual differences in anxiety sensitivity, or the fear of arousal-based sensations, is one important cognitive construct for smoking maintenance and relapse among Latinx persons who smoke. However, previous research has not examined if anxiety sensitivity is associated with motivational facets of smoking dependence among this tobacco disparities population. In the current study, anxiety sensitivity was explored in terms of smoking motives for primary, secondary, and overall cigarette dependence. Participants included 336 English-speaking Latinx adults in the US who smoked cigarettes daily (Mage = 35.53, SD = 8.65, 37.3% Female). Results indicated that anxiety sensitivity was statistically significantly and positively related to higher primary and secondary dependence motives and marginally statistically significant to cigarette dependence; findings were evident after adjusting for numerous theoretically relevant variables (e.g., depression). Overall, the current study is the first to document linkages between anxiety sensitivity and numerous motivational bases of tobacco dependence among Latinx persons who smoke from the US.

Reducing Fear and Enhancing Aesthetics: Orthodontic Management with Video Self-Modeling in an Adolescent with Autism Spectrum Disorder

Abstract Introduction Autism spectrum disorder (ASD) presents challenges in social interaction and communication, particularly in the context of orthodontic treatment where patients may experience heightened anxiety. This case report introduces an innovative approach that utilizes video self-modeling (VSM) to address these challenges and enhance the orthodontic treatment experience for adolescents with ASD. Case Report An 11-year-old female patient with ASD required orthodontic treatment. Conventional behavioral guidance techniques were unsuccessful because of the patient's anxiety and sensory sensitivity. Utilizing VSM, we crafted personalized video content to illustrate the dental procedure, significantly alleviating patient's fear and anxiety. This approach led to the successful completion of her orthodontic treatment. Conclusion This case report underscores the effectiveness of VSM as a valuable behavioral guidance technique in orthodontic treatment for adolescents with ASD. By alleviating anxiety and fear, VSM has the potential to significantly enhance the dental care experience and promote improved oral health and well-being in this specific patient population.

A - 40 The Impact of Early Access on Sports-Related Concussions in Youth Hockey Players

Abstract Purpose Sports-related concussions are the most common setting for adolescents to sustain a concussion. Delayed access to care is a risk factor for recovery and youth athletes have limited access to early intervention often due to lack of athletic trainer coverage. The purpose of this study was to evaluate the effect of early access on sports-related concussions in youth hockey players. Method Participants (n = 67) included youth athletes from hockey organizations who partnered with a local specialty concussion clinic. Athletes presented to clinic for care (median = 2 days) after sustaining a concussion. We examined whether the number of days since injury to initial exam (DSI) significantly predicted recovery time while controlling for common injury modifiers, such as symptom severity, anxiety sensitivity, and age. Recovery was measured in number of days since injury to the date of medical clearance. Results Multivariate general linear analyses indicated that DSI (M = 4.96, SD = 8.90), significantly predicted the number of recovery days (M = 12.85, SD = 9.47), with each day earlier to initial exam predicting almost one day faster recovery (B = 0.92; p < 0.001; ηp2 = 0.813). Variables of age (M = 13.78, SD = 2.59), anxiety sensitivity (M = 8.91, SD = 9.69), and concussion severity (M = 19.22, SD = 8.90), were not predictive recovery. Conclusions Early access resulted in faster medical clearance. This sample of youth hockey players do not have access to an athletic trainer to provide early intervention. Our results suggest that the ability to have early intervention through a specialty concussion clinic partnership resulted in faster recovery, highlighting the importance of continuing to explore and cultivate these relationships with youth sports.

Impact of Social Media Usage on the Variables of Anxiety and Reward Sensitivity among Medical Undergraduates

Impact of Social Media Usage on the Variables of Anxiety and Reward Sensitivity among Medical Undergraduates

Exploring Relations Between Unique Patient Characteristics and Virtual Reality Immersion Level on Anxiety and Pain in Patients Undergoing Venipuncture: Secondary Analysis of a Randomized Control Trial.

Virtual reality (VR) is a well-researched digital intervention that has been used for managing acute pain and anxiety in pediatric patients undergoing various medical procedures. This study focuses on investigating the role of unique patient characteristics and VR immersion level on the effectiveness of VR for managing pediatric pain and anxiety during venipuncture. The purpose of this study is to determine how specific patient characteristics and level of immersion during a VR intervention impact anxiety and pain levels for pediatric patients undergoing venipuncture procedures. This study is a secondary data analysis of 2 combined, previously published randomized control trials on 252 pediatric patients aged 10-21 years observed at Children's Hospital Los Angeles from April 12, 2017, to July 24, 2019. One randomized clinical trial was conducted in 3 clinical environments examining peripheral intravenous catheter placement (radiology and an infusion center) and blood draw (phlebotomy). Conditional process analysis was used to conduct moderation and mediation analyses to assess the impact of immersion level during the VR intervention. Significant moderation was found between the level of immersion and anxiety sensitivity when predicting postprocedural anxiety (P=.01). Patients exhibiting the highest anxiety sensitivity within the standard of care yielded a 1.9 (95% CI 0.9-2.8; P<.001)-point elevation in postprocedural anxiety relative to individuals with high immersion levels. No other significant factors were found to mediate or moderate the effect of immersion on either postprocedural anxiety or pain. VR is most effective for patients with higher anxiety sensitivity who report feeling highly immersed. Age, location of the procedure, and gender of the patient were not found to significantly impact VR's success in managing levels of postprocedural pain or anxiety, suggesting that immersive VR may be a beneficial intervention for a broad pediatric population. ClinicalTrials.gov NCT04268901; https://clinicaltrials.gov/study/NCT04268901.

Psychological factors in symptom severity and quality of life in Raynaud's phenomenon.

Despite emotional stress being recognised as a key trigger for Raynaud's phenomenon episodes, research in the area is still in its infancy. This study investigated the role of psychological factors relating to symptom severity and quality of life, and differences between Raynaud's types (primary and secondary) to further inform the development of intervention in this field. A cross-sectional design was used. Two hundred and ten adults with Raynaud's completed an online questionnaire measuring stress, anxiety, depression, anxiety sensitivity, beliefs about emotions, symptom severity and quality of life. Primary and secondary Raynaud's groups differed in anxiety (p < .004), symptom severity (p < .001) and quality of life (p < .001). Stepwise multiple regressions indicated anxiety and Raynaud's type explained 23% variance in hand symptom severity (p < .001); anxiety, Raynaud's type and anxiety sensitivity explained 29% variance in symptom severity (global impact, p < .001); depression, Raynaud's type and anxiety sensitivity explained 32% variance in quality of life (p < .001). Results highlight the importance of psychological factors in Raynaud's phenomenon, indicating possible targets for treatment. Interventions such as cognitive behavioural therapy, which target both physical and psychological wellbeing, bear some promise as an adjuvant therapy for this group.

Developing a Model of Readiness to Use Drugs in Lorestan University Students Based on Anxiety Sensitivity and Sensation Seeking with the Mediating Role of Negative Affectivity: A Descriptive Study

Developing a Model of Readiness to Use Drugs in Lorestan University Students Based on Anxiety Sensitivity and Sensation Seeking with the Mediating Role of Negative Affectivity: A Descriptive Study

Psychometric properties of anxiety sensitivity Index-3 among Chinese college students and its preliminary application among this population experiencing campus lockdown.

Anxiety sensitivity (AS) refers to fear of anxiety-related sensory arousal and has been revealed to be associated with increased psychological distress and mental problems. Although Anxiety Sensitivity Index-3 (ASI-3) has been confirmed to be effective in evaluating this construct, whether it is consistently applicable in college students is still elusive. The present study aimed to examine the psychometric properties and measurement invariance of Chinese version of ASI-3 (C-ASI-3) among college students experiencing campus lockdown due to novel coronavirus disease 2019 (COVID-19) pandemic. A total of 1532 Chinese college students (397, 25.9% males) aged between 16 and 25 were included in this study. Confirmatory factor analysis (CFA) was used to verify the factor structure of C-ASI-3. Multi-group CFA was conducted for analysis of measurement invariance with regard to gender. McDonald's omega values were computed for examination of scale reliability. For criterion, convergent, and divergent validity, average variance extracted (AVE) values for C-ASI-3 subscales, difference between square root of AVE for each factor and inter-factor correlation, as well as pearson correlation and partial correlation between the C-ASI-3 and other three scales, including the Depression, Anxiety, and Stress Scale-21 (DASS-21), the State-Trait Anxiety Inventory (STAI), and the Fear of COVID-19 scale (FCV-19S) were evaluated. The C-ASI-3 presented a three-factor scale structure with fit indices being as follows: χ2/df = 11.590, CFI = 0.938, RMSEA = 0.083, SRMR = 0.042. Strict measurement invariance was reached across gender. Regarding convergent validity, the C-ASI-3 had a high correlation with the DASS-21 (r = 0.597, p < 0.01) and the STAI (r = 0.504, p < 0.01). All AVE values for C-ASI-3 subscales were above 0.5. In terms of divergent validity, the C-ASI-3 had medium correlation with the FCV-19S (r = 0.360, p < 0.01). Square of root of AVE for each factor was higher that inter-factor correlation. McDonald's omega values of the three dimensions ranged from 0.898 ~ 0.958. The C-ASI-3 has acceptable psychometric properties among college students. College students with different gender have consistent understanding on the scale construct.

Internalizing personality traits and coping motivations for gaming during the COVID-19 pandemic: A cross-lagged panel mediation analysis

Anxiety sensitivity and hopelessness are two traits that have been previously linked to increased gaming problems. Research in the early stages of the COVID-19 pandemic showed that emotionally vulnerable individuals were turning to video games as a means of coping with their distress. However, more research is needed on the long-term and enduring pathways from internalizing traits to time spent gaming during COVID-19, after the lockdowns and preventative measures had been lifted. As such, the current study employs a multi-wave longitudinal study that predicted that those participants who experience high levels of anxiety sensitivity or hopelessness would use gaming as a means to cope with their emotional discomfort, resulting in increased gaming behaviours. A sample of 1,001 American gamers (Mage = 38.43, SD = 12.11, 53.2% female) completed three surveys through Mechanical Turk, with the first occurring in July 2021, and subsequent surveys spaced three months apart. This study measured participants’ baseline anxiety sensitivity and hopelessness using the Substance Use Risk Profile. At each time point, participants were asked to recall their average time spent gaming over the past month using a Timeline Follow-Back method, and answer questions related to their coping motivations for gaming using the Motives for Online Gaming Questionnaire. Coping motives consistently predicted time spent gaming at the next timepoint. Furthermore, we found evidence that high levels of anxiety sensitivity at baseline predicted greater future time spent gaming at Time 3, through greater coping motives at Time 2. Hopelessness was correlated with coping motives and time spent gaming at baseline, but did not relate to these variables across time. Anxious individuals who were gaming to cope during the COVID-19 pandemic may be at higher risk for excessive gaming. This may be particularly true for individuals who are higher in anxiety sensitivity. Future research should aim to understand how the relationships between anxiety sensitivity, coping motivations, and time spend gaming exist in the context of symptoms of gaming disorder and functional impairments that exist due to excessive gaming.

Examining the Mediating Role of Resilience and Life Satisfaction in the Relationship Between Anxiety Sensitivity and Perceived Stress.

This study examines the mediation role of life satisfaction and resilience variables in the relationships between anxiety sensitivity and perceived stress. The data was collected with the Anxiety Sensitivity Index-3, Life Satisfaction Scale, Perceived Stress Scale, and Brief Psychological Resilience Scale from 347 university students (Mage = 23.15, SD = 5.15; 70% girls, 30% boys). The analyses were examined by structural equation modeling using AMOS 24. The findings suggest that students with high anxiety sensitivity and perceived stress have low resilience and life satisfaction levels. More importantly, resilience and life satisfaction were found to have partial mediation. As a result, it is seen that anxiety sensitivity has a significant effect on reducing perceived stress by increasing students' resilience and life satisfaction. Therefore, this situation facilitates decreased anxiety levels, greater satisfaction with life, and more robust mental health.

Validity and Reliability of Anxiety Sensitivity Index-3 (ASI-3) Indonesian Version In Clinical and Non-Clinical Samples

Validity and Reliability of Anxiety Sensitivity Index-3 (ASI-3) Indonesian Version In Clinical and Non-Clinical Samples

Comparing the effectiveness of group mindfulness-based cognitive therapy with emotion-focused therapy on anxiety sensitivity in patients with peptic ulcer

Introduction: Peptic ulcer is known as a psychosomatic disease that is closely related to anxiety and stress. This research aimed to compare the effectiveness of mindfulness-based cognitive therapy and emotion-oriented therapy on anxiety sensitivity in patients with peptic ulcers. Method: This semi-experimental study was conducted based on a pre-test-post-test-follow-up design and a control group. In total, 45 peptic ulcer patients who had referred to specialized and sub-specialized gastroenterology clinics in Mashhad, Iran in 2023 were enrolled in the study. The participants were selected by available sampling method and randomly replaced in two experimental groups and one control group (n=15). The experimental groups received intervention in the form of eight 90-minute sessions of emotion-focused therapy and mindfulness-based cognitive therapy. The control group did not receive training during the research. Participants completed the Taylor and Cox (1998) Anxiety Sensitivity Questionnaire before, immediately after, and three months after the interventions. The obtained data were analyzed by repeated measure ANOVA in SPSS software. Results: The findings showed that emotion-focused therapy and mindfulness-based cognitive therapy were effective on the anxiety sensitivity of patients with peptic ulcer (P&lt;0.001). However, no significant difference was observed between the effectiveness of the two treatment approaches (P=0.78). Conclusion: The results showed that emotion-focused therapy and mindfulness-based cognitive therapy can be used to improve anxiety-related factors among patients with peptic ulcers.

Vulnerability Factors, Adjustment, and Opioid Misuse in Chronic Noncancer Pain Individuals

Several person variables predate injury or pain onset that increase the probability of maladjustment to pain and opioid misuse. The aim of this study was to evaluate the role of 2 diathesis variables (impulsiveness and anxiety sensitivity [AS]) in the adjustment of individuals with chronic noncancer pain and opioid misuse. The sample comprised 187 individuals with chronic noncancer pain. The hypothetical model was tested using correlation and structural equation modeling analyses. The results show a significant association between impulsiveness and AS and all the maladjustment variables, and between impulsiveness and AS and opioid misuse and craving. However, although the correlation analysis showed a significant association between adjustment to pain and opioid misuse, the structural equation modeling analysis showed a nonsignificant association between them (as latent variables). The findings support the hypothesis that both impulsiveness and AS are vulnerability factors for maladaptive adjustment to chronic pain and opioid misuse. PerspectiveThis article adds to the empirical literature by including AS and impulsiveness as antecedent variables in a model of dual vulnerability to chronic pain maladjustment and opioid misuse. The findings suggest the potential utility of assessing both factors in individuals in the first stages of chronic pain.

An Integrated Therapeutic Application Using Elements of Cognitive Behavioral Therapy and Mindfulness-based Cognitive Therapy in Treatment of Panic Disorder

The commonly used protocol for the treatment of panic disorder has been the application of cognitive behavioral therapy (CBT). With the advent of third-wave psychotherapies such as acceptance and commitment therapy, dialectical behavioral therapy, and mindfulness-based cognitive therapy (MBCT), which focuses on experiential acceptance, there have been variations in the treatment of panic disorder. However, no case report has adopted an integrated treatment protocol using elements of CBT and MBCT. Here, we have presented a practical psychotherapy report of a 31-year-old woman who was treated over 16 sessions using such an integrated treatment protocol based on her personality and clinical profile. During the first phase of treatment, components of CBT were introduced to help her obtain firsthand evidence of her catastrophic misinterpretation of bodily sensations and to change her underlying threat schemas related to physical sensations. Aspects of MBCT were implemented in the intermediate phase to allow awareness and observation of her anxiety sensitivity, discourage immediate reactivity, and reduce overall catastrophizing tendencies. Moreover, MBCT also served to prevent relapse by enriching her overall quality of life by cultivating present-moment awareness through encouraging full engagement in experiences rather than being consumed by future-oriented concerns.

Anxiety sensitivity and COVID-19 mental health, fatigue, and well-being: a longitudinal examination among adults from the United States during March–October 2020

ABSTRACT There is widespread empirical evidence that the COVID-19 pandemic contributed to elevated risk of mental and physical health symptoms and decreased quality of life. The present investigation sought to examine if individual differences in anxiety sensitivity was associated with mental health, psychosomatic, and well-being among a sample of US adults during a 6-month period early in the COVID-19 pandemic. Employing longitudinal research methodology, we tested the hypothesis that the anxiety sensitivity global factor would be related to increased risk of anxiety, depression, fatigue, and lower well-being. Secondary analyses evaluated the lower order anxiety sensitivity factors for the same criterion variables. The sample consisted of 778 participants with an average age of 37.96 (SD = 11.81; range 18–73). Results indicated that, as hypothesized, anxiety sensitivity was associated with increased risk for more severe anxiety, depression, fatigue, and lesser well-being; the observed effects of anxiety sensitivity were relatively robust and evident in adjusted models that controlled for numerous theoretically and clinically relevant factors (e.g. perceived health status). Overall, these results suggest that pandemic functioning could likely be improved via interventions that target elevated anxiety sensitivity as a vulnerability factor for a broad range of aversive psychosomatic symptoms and personal well-being.

Exploratory Structural Equation Modeling Analysis of the Anxiety Sensitivity Index 3.

Anxiety sensitivity is associated with the onset and progression of various emotional disorders. The Anxiety Sensitivity Index 3 (ASI-3) is a self-report scale for anxiety sensitivity. This study aims to resolve the ongoing controversy about the factorial structure of the ASI-3 using exploratory structural equation modeling (ESEM), a newly advanced technique. Confirmatory factor analysis (CFA), ESEM, bifactor-CFA, and bifactor-ESEM were used to investigate the factorial structure of the ASI-3. Three hundred Korean college students (female = 195, age: 21.74 ± 2.34) filled out the ASI-3 and the Distress Intolerance Index. The bifactor-ESEM model exhibited a model fit superior to the 4 alternative models. The general factor showed higher loadings and reliability and explained common variance than the 3 specific factors in the bifactor-ESEM model. Most items reflected the global factor, but 6 items (Items 2, 3, 5, 7, 10, and 17) from the specific factors had insufficient loadings. Moreover, the global factor of the ASI-3 was associated with distress intolerance scores, indicating adequate criterion-related validity. The factorial structure of the ASI-3 is best described as a bifactor-ESEM model for Korean college students. Additionally, the bifactor-ESEM model of the ASI-3 includes a strong global factor that explains a large amount of the observed variance in the ASI-3 items.

Performance-based acceptance and commitment training in a collegiate flight program

Students in flight training programs experience high levels of stress and anxiety that may impede their performance on practical exams. The restrictive nature of Federal Aviation Administration (FAA) regulations and perceived negative consequences of seeking mental health treatment further exacerbates these challenges. This study examined the efficacy of performance-based acceptance and commitment training (ACT) in enhancing psychological flexibility, resilience, and mental well-being as well as improving FAA practical examination outcomes among collegiate flight training students. A randomized controlled trial was used to compare outcomes between students receiving a six-week ACT intervention (n = 23) and a control group (n = 27). The planned sample size of 100 was not achieved, thus, the analyses were underpowered and should be cautiously interpreted. Results indicate significant improvements among intervention participants in anxiety sensitivity (g = 0.43) and psychological flexibility (g = 0.58) compared to those in the control group. However, no significant differences in examination pass rates or time to completion were found between groups. To examine idiographic differences, individual change scores were plotted, demonstrating the heterogeneity of effects between participants. Potential explanations for the intervention's lack of effect on practical exam performance are discussed and suggestions are given to improve future performance-based interventions in this unique context.

C57BL/6J offspring mice reared by a single-mother exhibit, compared to mice reared in a biparental parenting structure, distinct neural activation patterns and heightened ethanol-induced anxiolysis.

Parenting experiences with caregivers play a key role in neurodevelopment. We recently reported that adolescents reared by a single-mother (SM) display an anxiety-prone phenotype and drink more alcohol, compared to peers derived from a biparental (BP) rearing condition. To investigate if SM and BP offspring infant mice exhibit differential sensitivity to ethanol-induced locomotor activity and differential activity patterns in brain areas related to anxiety response. We also analyzed anxiety response and ethanol-induced anxiolysis in SM and BP adolescents. Mice reared in SM or BP conditions were assessed for (a) ethanol-induced locomotor activity at infancy, (b) central expression of Fos-like proteins (likely represented mostly by FosB, a transcription factor that accumulates after chronic stimuli exposure and serves as a molecular marker of neural plasticity) and cathecolaminergic activity, and (c) anxiety-like behavior and ethanol-induced anxiolysis in adolescence. Infant mice were sensitive to the stimulating effects of 2.0g/kg alcohol, regardless parenting structure. SM mice exhibited, relative to BP mice, a significantly greater number of Fos-like positive cells in the central amygdala and basolateral amygdala nuclei. Ethanol treatment, but not parenting condition, induced greater activation of dopaminergic neurons in ventral tegmental area. SM, but not BP, adolescent mice were sensitive to ethanol-induced anxiolysis. These results highlight the complex relationship between parenting experiences and neurodevelopment. The SM parenting may result in greater neural activation patterns in brain areas associated with anxiety response, potentially contributing to increased basal anxiety and alcohol sensitivity.