Antioxidant Secondary Metabolites Research Articles

Integrated transmission electron microscopy and proteomic analyses reveal the cytoarchitectural response to cucumber mosaic virus infection in tobacco

Cucumber mosaic virus (CMV) causes huge economic losses to agriculture every year; thus, understanding the mechanism of plant resistance to CMV is imperative. In this study, an integrated analysis of transmission electron microscopy (TEM) observations and proteomic results was used to identify cytoarchitectural differences in Nicotiana tabacum cv. NC82 (susceptible) and cv. Taiyan 8 (T.T.8; resistant) following infection with CMV. The TEM observations showed that the structure of the chloroplasts and mitochondria was severely damaged at the late stage of infection in NC82. Moreover, the chloroplast stroma and mitochondrial cristae were reduced and disaggregated. However, in T.T.8, organelle structure remained largely intact Selective autophagy predominated in T.T.8, whereas non-selective autophagy dominated in NC82, resembling cellular disorder. Proteomic analysis of T.T.8 revealed differentially expressed proteins (DEPs) mostly associated with photosynthesis, respiration, reactive oxygen species (ROS) scavenging, and cellular autophagy. Biochemical analyses revealed that ROS-related catalase, autophagy-related disulfide isomerase, and jasmonic acid and antioxidant secondary metabolite synthesis-related 4-coumarate:CoA ligase (Nt4CL) exhibited different trends and significant differences in expression in the two cultivars after CMV inoculation. Furthermore, mutant phenotyping verified that reduced Nt4CL expression impaired resistance in T.T.8. The identified DEPs are crucial for maintaining intracellular homeostatic balance and likely contribute to the mechanism of CMV resistance in tobacco. These findings increase our understanding of plant cytological mechanisms conferring resistance to CMV infection.

Variation of antibacterial and antioxidant secondary metabolites and volatiles in leaf and callus extracts of Phulai (Acacia Modesta Wall.)

BackgroundAcacia species are economically significant as medicinal plants that have been utilized since ancient times. Acacia modesta has been reported to possess potent antibacterial and antioxidant properties, but its growth rate is slow. In this study, we hypothesized that inducing callus in vitro from A. modesta could enhance the production of antibacterial and antioxidant secondary metabolites, thereby circumventing the issues of slow growth and excessive harvesting of the plant.ResultsThe callus was induced from axillary buds on MS medium supplemented with 1 mg/L of 2,4-D and 1 mg/L of BAP. The secondary metabolites, volatile compounds, antibacterial activity, and antioxidant activity of the callus and parent plant leaf extracts were evaluated. The results revealed that the content of phenolics and flavonoids, the number of volatile compounds, and the antibacterial and antioxidant activities of the callus extract were significantly enhanced (P ≤ 0.05) compared to the leaf extract. The antibacterial and antioxidant effects were strongly correlated with the total phenolic and flavonoid content in the extracts.ConclusionsOur findings suggest that in vitro callus culture increases the production of phenolics, flavonoids, and volatile compounds. This subsequently enhances the antibacterial and antioxidant properties of A. modesta.

Antioxidant Activity of Ethanol Extract of Chinese Petai Peel (Leucaena leucocephala (Lam.) de Wit) Using DPPH (1,1-diphenil-2-picrylhydrazyl) Method

The Chinese petai plant (Leucaena leucocephala (Lam.) de Wit) has been used in various systems of traditional medicine for the treatment of various diseases in humans. The Chinese petai plant (Leucaena leucocephala (Lam.) de Wit) contains antioxidant secondary metabolites that can inhibit oxidation reactions by binding to free radicals and highly reactive molecules. The purpose of this study was to determine the class of chemical compounds contained in the ethanol extract of Chinese petai peel and the antioxidant activity of the ethanol extract of Chinese petai peel (EEKPC). The stages of this research included: collection and processing of simplicia; preparation of the extract by maceration with 70% ethanol; characterization test of simplicia powder; phytochemical screening of ethanol extract of petai cina; antioxidant activity test of EEKPC using the DPPH (1,1-diphenyl-2-pikrilhidrazyl) free radical scavenging method using UV-Vis spectrophotometry at a wavelength of 516 nm. The results of the phytochemical screening examination of Chinese Petai Peel Ethanol Extract (EEKPC) contained alkaloids, flavonoids, saponins, tannins, and triterpenoids. The results of measuring the antioxidant activity of EEKPC showed strength in the "strong" category with an IC50 value of 91.0189 μg/ml.

Early Physiological, Cytological and Antioxidative Responses of the Edible Halophyte Chenopodium quinoa Exposed to Salt Stress.

Quinoa (Chenopodium quinoa Willd.) is a plant of South American origin recently valorized for its nutritional and nutraceutical properties in human diet. Quinoa is cultivated in many parts of the world, with a selection of varieties with good adaptability to extreme climatic conditions and salt stress. The variety Red Faro, native to southern Chile but harvested in Tunisia, was considered for salt stress resistance, considering its seed germination and 10-day seedling growth at increasing doses of NaCl (0, 100, 200 and 300 mM). Seedlings were spectrophotometrically analyzed for antioxidant secondary metabolites (polyphenols, flavonoids, flavonols and anthocyanins), antioxidant capacity (ORAC, oxygen radical absorbance capacity, DPPH*, 2,2-diphenyl-1-pic-rylhydrazyl), antioxidant enzyme activity (superoxide dismutase (SOD), guaiacol peroxidase (GPX), ascorbate peroxidase (APX) and catalase (CAT)) and mineral nutrient content in root and shoot tissues. Cytogenetic analysis of root tip was performed to check for meristematic activity and the possible presence of chromosomal abnormalities induced by salt stress. The results indicated a general increase in antioxidant molecules and antioxidant enzymes NaCl dose-dependent, no effects on seed germination but negative effects on seedling growth, and little effect on root meristems mitotic activity. These results indicated that stress conditions can induce an increase in biologically active molecules that could be used for nutraceutical purposes.

Antimicrobial Activities of Medicinal Plant on the Oral Diseases

Herbal therapy has long been used to treat and control human diseases including mouth diseases and disorders. Also, it can minimize the potential side effects of chemical drugs. However, may be a side effects appear from plants or herbs therapy. Most of the challenges with herbal therapy revolves around inadequate information about the effect of herbs in the mouth, the mechanism of action, and potential side effects. There are several herbs and plants described in this paper that have anti-bacterial, anti-viral, anti-fungal, anti-disorders and anti-inflammatory in oral cavity. It includes 31 medicinal plants and herbs: Alakata pepper, Aloe vera, Airy shaw, Banana plant, Bird eye view, Bitter leaves, Bush pepper, Camelina, Cashew nut, Castor, Cinnamon, Clove, Common coleus, Common wire weed, Cypress, Fennel, Garcinia, Garden eggplant, Garlic, Ginger, Holy basil, Maca, Mint, Mexican tea, Neem, Okra, Onion, Orange fruits, Purple coneflower, Sunset shrub and Turmeric that act as alternative management option to current treatments for oral conditions such as caries, gingivitis, periodontitis, oral ulcers. In addition to, inflammation treatment after extraction, reduction dry mouth, pain, anesthesia, ill-fitting dentures. The current review of literature provides a summary of secondary metabolites most commonly used medicinal herbs and plants in maintaining oral health. They can be used in different forms such as mouthwashes, toothpastes, topical agents or local drug delivery devices. These findings show the role of antioxidant secondary metabolites in inhibiting the growth of oral pathogens and reducing oral diseases and mouth disorders.

Applications of Antioxidant Secondary Metabolites of Sargassum spp.

Sargassum is one of the largest and most diverse genus of brown seaweeds, comprising of around 400 taxonomically accepted species. Many species of this genus have long been a part of human culture with applications as food, feed, and remedies in folk medicine. Apart from their high nutritional value, these seaweeds are also a well-known reservoir of natural antioxidant compounds of great interest, including polyphenols, carotenoids, meroterpenoids, phytosterols, and several others. Such compounds provide a valuable contribution to innovation that can translate, for instance, into the development of new ingredients for preventing product deterioration, particularly in food products, cosmetics or biostimulants to boost crops production and tolerance to abiotic stress. This manuscript revises the chemical composition of Sargassum seaweeds, highlighting their antioxidant secondary metabolites, their mechanism of action, and multiple applications in fields, including agriculture, food, and health.

Nitric oxide regulates spearmint (Mentha spicata L.) responses to phenolic acids: growth, phenolics, and antioxidant capacity

Given the widespread recognition of the health risks and environmental damages caused by synthetic herbicides and fertilizers, it is more than ever necessary to unravel the mechanisms underlying plant responses to naturally derived bioactive substances. Phenolic acids constitute a group of aromatic compounds that, by showing both growth-promoting and allelopathic effects, have gained momentum over the past years. We aimed to investigate the effects of some common benzoic acid derivatives, namely vanillic acid (VA), p-hydroxybenzoic acid (pHBA), gallic acid (GA), and salicylic acid (SA), and the alleviative effects of nitric oxide (NO) on phenolic acid-induced inhibition in growth parameters in spearmint (Mentha spicata L.) shoot and underlying mechanisms. pHBA and VA at 0.5 mM were the most influential phenolic acids in the inhibition of growth and increasing the contents of malondialdehyde (by 119% and 83% respectively) and H2O2 (by 83% and 108% respectively) and decreasing chlorophyll content despite accelerating the activities of catalase and superoxide dismutase. In contrast, 0.5 mM SA and 0.05 mM GA significantly increased shoot fresh weight (by 85.1% and 48.1% respectively) and the accumulation of total phenolics (by 302% and 31% respectively) and anthocyanins (by 79% and 49% respectively) and stimulated phenylalanine ammonia lyase (PAL) activity (by 140.4% and 107.7% respectively). NO at 100 µM was highly effective in the alleviation of pHBA and VA-induced growth reduction and lipid peroxidation. In conclusion, NO improved the negative effects of pHBA and VA by increasing PAL activity and enhancing the contents of antioxidative secondary metabolites.

Is the Invasiveness of Pittosporum undulatum in Eucalypt Forests Explained by the Wide Ranging Effects of Its Secondary Metabolites?

Climate change is a driver of biodiversity loss, often favouring invasive species such as in the case of Pittosporum undulatum in Eucalyptus forests of south-eastern Australia. We tested whether the invasiveness of P. undulatum is due to the release of secondary metabolites with allelopathic action inhibiting other species germination or to the content of antioxidant secondary metabolites. We compared the germination of P. undulatum and Eucalyptus ovata seeds on different substrates watered with different leachates. Polyphenolic compounds, saponins and tannins of Eucalyptus spp. and P. undulatum leaf extracts were quantified. Biogenic Volatile Organic Compounds were collected in the field and analyzed to compare the emissions in eucalypt forests with and without P. undulatum. Eucalyptus germination rates were not affected by different leachates and no allelopathic compounds were identified in P. undulatum leachate. Flavonoids and tannins characterized Eucalyptus leachates, while P. undulatum leachates showed high hydroxycinnamic acids content. The forests invaded by P. undulatum were characterized by high levels of monoterpenes, whereas the forest lacking P. undulatum were dominated by sesquiterpenes. Our results suggest that the invasiveness of P. undulatum may be due to the high content in secondary metabolites that play a protective role against abiotic stresses rather than the release of allelopathic compounds.

Zinc biofortification of hydroponically grown basil: Stress physiological responses and impact on antioxidant secondary metabolites of genotypic variants.

Ocimum basilicum L. is an aromatic plant rich in bioactive metabolites beneficial to human health. The agronomic biofortification of basil with Zn could provide a practical and sustainable solution to address Zn deficiency in humans. Our research appraised the effects of biofortification implemented through nutrient solutions of different Zn concentration (12.5, 25.0, 37.5, and 50 µM) on the yield, physiological indices (net CO2 assimilation rate, transpiration, stomatal conductance, and chlorophyll fluorescence), quality, and Zn concentration of basil cultivars 'Aroma 2' and 'Eleonora' grown in a floating raft system. The ABTS, DPPH, and FRAP antioxidant activities were determined by UV-VIS spectrophotometry, the concentrations of phenolic acids by mass spectrometry using a Q Extractive Orbitrap LC-MS/MS, and tissue Zn concentration by inductively coupled plasma mass spectrometry. Although increasing the concentration of Zn in the nutrient solution significantly reduced the yield, this reduction was less evident in 'Aroma 2'. However, regardless of cultivar, the use of the maximum dose of Zn (50 µM) increased the concentration of carotenoids, polyphenols, and antioxidant activity on average by 19.76, 14.57, and 33.72%, respectively, compared to the Control. The significant positive correlation between Zn in the nutrient solution and Zn in plant tissues underscores the suitability of basil for soilless biofortification programs.

Diverse chemical modifications of the chlorogenic acid composition of Viscum combreticola Engl.: A premise for the state of readiness against excessive sunlight exposure.

Mistletoe plants that are positioned on the canopy of their hosts are more susceptible to UV radiation exposure. These aerial plants are resistant to damage by UV radiation due the presence of epidermal constituents such as the cuticle, cork layer, trichomes and antioxidant secondary metabolites. In response to the photo-oxidative stress associated with UV exposure, plants generally deploy photo-protective responsive mechanisms that involve the biosynthesis of UV absorbing phenolic compounds such as chlorogenic acids (CGAs). The hydroxycinnamic acid moieties of these CGAs are predominantly in the trans configuration, naturally. However, excessive sunlight exposure of plants containing these compounds can result in geometrical isomerisation, characterized by the formation of cis isomers. Therefore, in this study, the effect of UV light radiation on the CGA composition of Viscum combreticola Engl. (Santalacaeae) plants using an in vitro model was unravelled through UHPLC-q-TOF-MS-based metabolic profiling. Interestingly, the findings of this study revealed that this plant has a diverse chemical composition of CGAs that is characterized by epimerization, monoacylation, homodiacylation and heterodiacylation of the quinic acid (QA), thereby, contributing to the state of readiness in these plants against sunlight or UV exposure. In addition to the commonly reported cinnamoyl containing heterodiacylated CGAs, hydroxybenzoyl containing heterodiacylated CGAs were also reported in this study. Moreover, cis isomers (24 in total) of some CGAs were identified in the non-irradiated samples and the formation of these compounds has been reported to help plants in the mitigation of photo-oxidative stress. An additional 28 cis isomers of CGAs and HCA derivatives were observed in the UV-irradiated samples, hence, further increasing the complexity of the metabolome of this plant, with a total of 108 compounds identified in this study. The presence of epimers, positional and geometrical isomers of these compounds could be a biochemical strategy to maximize the chemical arsenal of this plant to withstand the photo-oxidative stress posed by UV radiation from the sunlight. Due to purported pharmacological properties associated with the identified compounds these parasitic plants can be a rich source of prospective therapeutic compounds that can be employed as drug discovery leads. Moreover, UV radiation might be essential in future to produce potent drugs since plants naturally produce these compounds in low quantities.

Evaluation of the Use of Elicitors for the Production of Antioxidant Compounds in Liquid Cultures of Ganoderma curtisii from Costa Rica.

The use of substances or conditions as elicitors can significantly increase the production of secondary metabolites. In this research, the effects of different elicitors on the production of antioxidant secondary metabolites were evaluated in a strain of Ganoderma sp. The elicitors tested were pH changes in different growth phases of the fungus (pH 3, 5.5 and 8), different concentrations of peptone as a nitrogen source (1 g/L and 10 g/L), and the addition of chemical agents to the culture medium (ethanol, growth regulators, and salts). The alkaline pH during the stationary phase and the high availability of nitrogen were effective elicitors, producing cultures with higher antioxidant activity (37.87 g/L and 43.13 g/L dry biomass) although there were no significant differences with other treatments.

Influence of urban gardening conditions on the concentration of antioxidant secondary plant metabolites in kale

Influence of urban gardening conditions on the concentration of antioxidant secondary plant metabolites in kale

Study on South African Indigenous Teas-Antioxidant Potential, Nutritional Content, and Hypoxia-Induced Cyclooxygenase Inhibition on U87 MG Cell Line.

Background: This study comparatively assessed seven indigenous traditional tea plants on several attributes that included antioxidant, nutritional, caffeine contents, and cyclooxygenase activity. Methodology: Nutritional content of all tea plants were determined for energy, fat, carbohydrates, total sugars, dietary fiber and amino acids. Antioxidant potential and the antioxidant potentiating secondary metabolites were also measured and compared. Further, we investigated the tea plants for any role they would have on cyclooxygenase (COX) activity on cobalt chloride (CoCl2) induced human glioma cell lines (U87MG). Results: The tea plants were found non-cytotoxic at concentrations tested against the human Chang liver and HeK 293 kidney cells and were found to be naturally caffeine free. The lowest and highest extraction yield among the tea plants was 7.1% for B. saligna and 15.48% for L. scaberrimma respectively. On average, the flavonol content was 12 to 8 QE/g, ORAC 800 µmol TE/g, TEAC 150 µmol TE/g, FRAP 155 µmol AAE/g, polyphenols 40 mg GAE/g, flavanols 0.35 mg CE/g, flavonols 12 mg QE/g and total flavonoid content (TFC) 180 µg QE/mg. The COX activity has been found to be inhibited by a dose-dependent manner by L. scaberrimma, B. saligna and L. javanica. Conclusion: The results further support competitive value of tea plants and need for improved and further development.

A Comparative Review of Plant and Microbial Antioxidant Secondary Metabolites

A Comparative Review of Plant and Microbial Antioxidant Secondary Metabolites

Elicitation of Submerged Adventitious Root Cultures of Stevia rebaudiana with Cuscuta reflexa for Production of Biomass and Secondary Metabolites.

Stevia rebaudiana is an important medicinal plant that belongs to the Asteraceae family. The leaves of Stevia rebaudiana are a rich source of many health-promoting agents such as polyphenols, flavonoids, and steviol glycoside, which play a key role in controlling obesity and diabetes. New strategies such as the elicitation of culture media are needed to enhance the productivity of active components. Herein, the Cuscuta reflexa extracts were exploited as elicitors to enhance the productivity of active components. Cuscuta reflexa is one of the parasitic plants that has the ability to elongate very fast and cover the host plant. Consequently, it may be possible that the addition of Cuscuta reflexa extracts to adventitious root cultures (ADR) of Stevia rebaudiana may elongate the root more than control cultures to produce higher quantities of the desired secondary metabolites. Therefore, the main objective of the current study was to investigate the effect of Cuscuta reflexa extract as a biotic elicitor on the biomass accumulation and production of antioxidant secondary metabolite in submerged adventitious root cultures of Stevia rebaudiana. Ten different concentrations of Cuscuta reflexa were added to liquid media containing 0.5 mg/L naphthalene acetic acid (NAA). The growth kinetics of adventitious roots was investigated for a period of 49 days with an interval of 7 days. The maximum biomass accumulation (7.83 g/3 flasks) was observed on medium containing 10 mg/L extract of Cuscuta reflexa on day 49. As the concentration of extract increases in the culture media, the biomass gradually decreases after 49 days of inoculation. In this study, the higher total phenolics content (0.31 mg GAE/g-DW), total flavonoids content (0.22 mg QE/g-DW), and antioxidant activity (85.54%) were observed in 100 mg/L treated cultures. The higher concentration (100 mg/L) of Cuscuta reflexa extract considerably increased the total phenolics content (TPC), total phenolics production (TPP), total flavonoids content (TFC), total flavonoids production (TFP), total polyphenolics content (TPPC), and total polyphenolics production (TPPP). It was concluded that the extract of Cuscuta reflexa moderately improved biomass accumulation but enhanced the synthesis of phenolics, flavonoids, and antioxidant activities. Here, biomass’s independent production of secondary metabolites was observed with the addition of extract. The present study will be helpful to scale up adventitious roots culture into a bioreactor for the production of secondary metabolites rather than biomass accumulation in medicinally important Stevia rebaudiana.

Activity test of fruit and pomegranate seeds (Punica granatum l) as a hepatoprotector against white male Wistar rats


 Introduction: White pomegranate (P. granatum) is a species of the Punicaceae which is thought as hepatoprotector based on its antioxidant secondary metabolite compoundst.
 Aims: The purpose of study was to determine the hepatoprotector activity of white pomegranate fruit and seeds ethanol extract on male white rats Wistar strain. 
 Methods: This research is laboratory experimental which rats were grouped into 5 groups randomly. Normal, negative (given Carboxymethylcellulose sodium 1% orally), test dose 1,2,3 (given extract at a dose of 50 mg /200 g bodyweight of rat, 100 mg/200 g bodyweight of rat and 200 mg/200 g bodyweight of rat in Carboxymethylcellulose sodium 1% orally). Negative, test dose 1,2,3 induced with paracetamol 180 mg/200 g bodyweight of rat. 
 Results: From the statistical analysis, it was found that a significant difference between the negative with test dose 1, 2, and 3. The best hepatoprotector activity was produced by the test dose 3 with the percentage reduction in AST levels 91.62% and ALT 90.20%.

Chemical Characterization of Secondary Metabolite from the Endophytic Fungus Trichordema reecei isolated from The Twig of Syzygium aqueum

Endophytic fungi are microorganisms that live in plants, without negative effects and are mutually related to hosting plants. Exploration of bioactive compounds from Endophytic fungi is easier and cheaper because they do not require a large area, a short growing time, and uncomplicated mixed compounds. Endophytic fungi are new and patent base secondary metabolites but they are not extensively characterized and investigated for the exploration of raw materials for drugs. The purpose of this study was to obtain antioxidant secondary metabolites from Endophytic fungi that live in the Syzygium aqueum medicinal plant. In this study, Endophyticfungi were isolated from S. aqueum twigs and molecular identification. The secondary metabolites were isolated by chromatographic method and chemical structure identified by spectroscopy. Antioxidant activity was evaluated by method 1,1diphenyl-2-picryl hydrazyl (DPPH). Phylogenetic analysis showed the Endophytic fungi of S. aqueum twig have a high similarity with the Trichordema reecei twig 19MSr.B2.3. The secondary metabolites from the ethyl acetate extract of the liquid culture of the fungus were identified as (4-hydroxy-3-(4-hydroxyphenyl)-5 oxotetrahydrofuran-2-yl) methyl acetate with IC50= 75.13 ????g/mL. The secondary metabolites can be developed into starting molecules for potential antioxidant agents.

Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health

Plant-derived phytochemicals have been touted as viable substitutes in a variety of diseases. All over the world, dentists have turned to natural remedies for dental cure due to the negative possessions of certain antibacterial mediators used in dentistry. Antimicrobial and other drugs are currently in use, but they show some side effects. Since ancient times, antioxidant EOs have been used for different ailments and have grown in popularity over time. Several in vitro, in vivo, and clinical trials have shown the safety and effectiveness of antioxidant essential oils (EOs) in oral health obtained from medicinal plants. The current review of literature provides a summary of secondary metabolites, more specifically EOs from 20 most commonly used medicinal plants and their applications in maintaining oral health. Dental caries and periodontal diseases are the most common and preventable global infectious diseases, with diseases of the oral cavity being considered major diseases affecting a person’s health. Several clinical studies have shown a connection between oral diseases and oral microbiota. This review discusses the role of antioxidant secondary metabolites in inhibiting the growth of oral pathogens and reducing the formation of dental plaque, and as well as reducing the symptoms of oral diseases. This review article contributes a basic outline of essential oils and their healing actions.

Fingerprint Analysis of Herbal Raw Materials available in Market Belongs to Combretacea And Fabaceae family by HPTLC technique using antioxidant markers

The prime aim of the study is to notice the flavonoids, phenolic acids and xanthones in five commercial herbal raw materials namely Pterocarpum marsupium Bark, Ormocarpum cochinchinense leaf, Indigofera tinctoria leaf, Terminalia arjuna bark and Terminalia chebula fruit obtained from Fabaceae and Combretacea family used in daily domestic needs to confirm the presence of common antioxidant secondary metabolites in herbal raw materials. Results of the study clearly revealed that these raw materials from Fabaceae and Combretacea family contains flavonoids, phenolic acids and xanthones. The developed simultaneous HPTLC method can be employed for the routine investigations of flavonoids, phenolic acids and xanthones in herbal raw materials. Pterocarpum marsupium Bark, and Ormocarpum cochinchinense leaf, was ascertain the presence of Rutin and reveals 0.006%,0.051% respectively. Gallic acid was only orginate in Pterocarpum marsupium Bark of about 0.113%. Quercetin was found to be 0.061%, 0.239%, 0.336%,0.066% and 0.036% respectively in all tested five extracts. Catechin was found to be 0.203% in Terminalia arjuna bark. Mangiferin was found to be 0.009%. in Indigofera tinctoria leaf.

Comparative analysis of the antioxidant capacity and secondary metabolites accumulation in the fruits of rowan (Sorbus aucuparia L.) and some closely related species

The paper presents the results of studying fruits antioxidant properties of several species, previously combined into the genus Sorbus L. (Rosaceae family). Ripe fruits were collected in September 2020 from the plants of Cormus domestica (L.) Spach, Sorbus aucuparia L., Karpatiosorbus latifolia (Lam.) Sennikov & Kurtto and Torminalis glaberrima (Gand.) Sennikov & Kurtto from the collection of the Botanical Garden of the Oles Honchar Dnipro National University. Total phenolic content (TPC), total flavonoids content (TFC), ferric reducing antioxidant power (FRAP) and total antioxidant capacity (TAC) were determined both in the fruits peel and pulp. In the fruits of all species, higher values of the determined indicators were found in the fruit peel than in the pulp. Moderate and strong positive correlation was found between FRAP and TPC as well between FRAP and TFC both in peel and pulp of all studied species. At the same time, notable interspecific differences of the phytochemical traits were established, indirectly confirming the ambiguity of the taxonomy of the genus Sorbus L. According to the fruits antioxidant properties and secondary metabolites accumulation, species K. latifolia (broad-leaved whitebeam) and T. glaberrima (wild service-tree) are the most promising for cultivation in arid conditions of the central steppe of Ukraine.