The amount of total phenols and flavonoids and the antioxidant activity of leaf, stem, and rhizome methanolic extracts from a commonly consumedAnemopsis californicaunder different storage conditions were investigated. Storage conditions were at 50, 25, 4, and โ20ยฐC, protected or not from light, during 180 days. The inhibition of the elastase enzyme was also evaluated. The results demonstrated that leaf, stem, and rhizome methanolic extracts ofAnemopsis californicamaintain approximately up to 97 and 95% stability in phenolic content and antioxidant activity, respectively, when stored during 60 days at โ20ยฐC in the dark. Additionally, these extracts, principally from leaf and rhizome, showed an elastase inhibitory effect by 75 and 71.8%, respectively. Therefore, this study provides the basis for further research on the anti-inflammatory activity. On the other hand,Anemopsis californicacould comprise a good alternative of use as antioxidant in foods.