Antimicrobial Cotton Fabrics Research Articles

Antibacterial mechanism of water-soluble CeO2 nanoflowers and its product design in antibacterial application

Antibacterial surface coatings have attracted growing attention in the textile industry. In this study, water-soluble CeO2 nanoflowers were synthesized by a modified critical micelle antisolvent method, displaying the potential for mass production at a low cost. The structure and electronic states of CeO2 were investigated deeply. Moreover, the antibacterial mechanism of CeO2 was studied in depth. The results revealed that CeO2 nanoflowers with abundant oxygen vacancies can adsorb O2 and produce amounts of reactive oxygen species (ROS) by the electron transfer of Ce4+ and Ce3+. These compounds can destroy cell walls, resulting in the leakage of bacterial nucleic acids and proteins, leading to bacterial death. The CeO2 nanoflowers exhibited broad-spectrum antimicrobial properties and biological safety. The antibacterial cotton fabric was prepared by the impregnation method. Considering the material impregnation amounts and impregnation time, a new washing machine was designed to prepare the antibacterial fabric. In this work, fabrics were modified using CeO2 nanoflowers with a simple method suitable for mass production, showing great application potential in antimicrobial cotton fabric. In addition, in order to further expand the application field of CeO2 nanoflowers, antibacterial elevator button patches, antibacterial coatings and other products were designed.

Durable Antimicrobial Cotton Fabrics Prepared by Oxygen Plasma Treatment and Adsorption of Guanidine Salts

Durable Antimicrobial Cotton Fabrics Prepared by Oxygen Plasma Treatment and Adsorption of Guanidine Salts

Analysis of antiviral and antimicrobial activity of Opuntia Stricta (red prickly pear) extract treated cotton fabric by cationization technique for healthcare and hygiene textiles

The aim of this work is to produce an effective antiviral and antimicrobial cotton fabric with adequate wash fastness effects on the Opuntia Stricta (red prickly pear) extracted treated textile materials for healthcare and hygiene application. Since humans are more prone to bacterial and viral infections which are deadly and contagious, proper use of these fabrics will effectively reduce the spread of human pathogenic microorganisms. Cotton fabric is taken because it has a good absorbency, comfort and durability. Cotton fabric is subjected to cationization process using chitosan and sericin. The extract of plant Opuntia Stricta is obtained from its fruits by aqueous extraction technique. The Opuntia Stricta fruit are highly effective and possess various flavonoids that inhibit the growth and spread of human pathogenic microorganisms and the Opuntia Stricta extract were applied on to the cotton material using herbal dyeing technique. The effectiveness of the finished fabric were analyzed by AATCC method for qualitative evaluation of antimicrobial activity of the treated samples, its shows excellent zone of inhibition in both gram positive Staphylococcus aureus and gram negative bacteria Echerichia coli.

Silver nanoparticle@catechol formaldehyde resin microspheres: One-pot synthesis and application for producing durable antimicrobial cotton fabrics

Silver nanoparticles (Ag NPs) are widely utilized as antibacterial agents, but they are easily agglomerated and have weak adhesion to the substrate, resulting in low stability in the performance of Ag NPs modified antibacterial fabrics. In this work, a one-pot hydrothermal synthesis of silver nanoparticle@catechol formaldehyde resin microspheres (denoted as Ag@CFR) was developed using catechol, hexamethlenetetramine, and silver salts as precursors. When the catechol to silver salt ratio was adjusted to 10:1, monodisperse microspheres were synthesized with the incorporation of Ag NPs both on the surface and within. Ag@CFR could be uniformly dispersed in water, showed very high antimicrobial activity against S. aureus, E. coli, and C. albicans, and had a comparatively low level of cytotoxicity to mammalian cells. Subsequently, Ag@CFR were uniformly deposited and firmly adhered onto the fabric surface using the pad-dry-cure method, resulting in the production of durable antimicrobial cotton fabrics. Ag@CFR-coated fabrics showed very high antimicrobial activities and laundering durability, which presented a high bacteriostatic and fungistatic rate of 99.99% against S. aureus, E. coli, and C. albicans even after 50 laundering cycles. Ag@CFR-coated fabrics maintained good tensile properties, hand feel, and air permeability while presenting superhydrophilicity during the test. This work presents a pioneering attempt to modify fabrics using CFR coatings via a facile method, which is suitable for large-scale production and holds significant potential for widespread applications in various fields.

Nonleaching Antimicrobial Cotton Fabrics Finished with Hyperbranched Polylysine.

The choice of the antimicrobial agent and finishing process is very important for the activity, durability, and safety of antimicrobial fabrics. Here, a novel antimicrobial cotton fabric (HPL-CF) was constructed by covalently bonding an antimicrobial agent, hyperbranched polylysine (HPL), onto the surface of a cotton fabric (CF) pretreated with a silane coupling agent, 3-chloropropyltrimethoxysilane (CPTMS). The multiple amino groups contained in the periphery of HPL make it possible to react with the CF to form multiple bonds, which is beneficial to improve the durability and safety of HPL-CFs. The obtained HPL-CFs exhibited excellent antimicrobial activities against Escherichia coli (E. coli, Gram-negative bacteria), Staphylococcus aureus (S. aureus, Gram-positive bacteria), and Candida albicans (C. albicans, fungi) even when the CF was treated with HPL solution at the concentration of 0.5 wt %. HPL2.0-CFs maintained 98, >99, and >99% of antimicrobial ratios for E. coli, S. aureus, and C. albicans, respectively, after 50 equiv of domestic laundering cycles, surpassing the requirements of the AAA class. The halo method, cell compatibility, and skin irritation assays all prove the fine safety of HPL-CFs. This work demonstrates the great advantages of applying HPL in the antimicrobial finishing of fabrics.

Development of antimicrobial cotton fabrics by decoration with silver nanoparticles and activated carbon composite

Nanometer sized particulates demonstrate significant potential in various biomedical applications due to their large surface-to-volume ratio and exceptional physicochemical, electronic and mechanical properties. Additionally, the number of microbial infectious disease outbreaks has increased tremendously over the past decade, greatly impacting public health worldwide. In this article, we evaluate the antimicrobial activity of a cotton fabric (CF) impregnated with silver nanoparticles (AgNPs) and hemp hurd activated carbon (HHAC) (HHAC@AgNPs) composite (CF-HHAC@AgNPs). Field emission scanning electron microscopy and x-ray diffraction spectra of the CF-HHAC@AgNPs material revealed the presence of AgNPs and HHAC on the cotton fabric. Moreover, CF-HHAC@AgNPs shows excellent antimicrobial efficacy against Gram-positive and Gram-negative pathogens. The obtained results show that an HHAC@AgNPs-CF material can be prepared. It has an antimicrobial activity that suggests its potential as an inhibitory agent in various biomedical applications.

Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric

An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibacterial agents. Synthesis and characterization of pyridyl-thienyl acetohydrazide derivative (AHZ) using NMR (13C and 1H) and FTIR. Modification of cotton fabric (CF) with acetohydrazide (AHZ) and metal chlorides of divalent Cr, Mn, Co, Ni, Cu, and Zn and trivalent Fe, and Cr. SEM-EDX and Fourier-transform infrared were utilized to characterize cellulose-based cotton fabric (CF) attached to AHZ and their metal (M) complexes. Antimicrobial activity was examined against two types of bacteria, namely S. aureus and E. coli, and two types of fungi, namely C. albicans and A. flavus. All modified samples exhibited higher efficiency towards bacterial strains than fungal strains. In addition, cellulose modified with Ni (II) confers the most antibacterial protection efficiency.

Durable biobased hybrid compounds: Potential modifying agents for the development of functional cotton fabrics

The advancementof antibacterial, stain-resistant, and easy-to-clean multifunctional cotton fabrics finds its scientific appeal and practical value due to their multidisciplinary uses in pharmacy, sanitation, clinics, etc. In this investigation, the cotton fabric was immersed in chitosan- vinyltriethoxy silane (Ch-VTES) and N-(2-hydroxy)propyl-3-trimethylammonium chitosan chloride- vinyltriethoxy silane (HTACC-VTES), prepared via the cost-effective sol–gel process to produce self-cleaning and antimicrobial cotton fabrics for end-uses. The Ch-VTES and HTACC-VTES modified cotton fabrics showed encouraging water contact angles of 102° and 139° respectively i.e. closer to superhydrophobicity as well as strong self-cleaning behavior without compromising the physicochemical properties of unmodified cotton fabric. Notably, the modified fabric demonstrated enchanting bacterial killing efficiency with a noticeable zone of inhibition against E. coli (17 mm for Ch-VTES and 21 mm for HTACC-VTES modified fabrics) and S. aureus (20 mm for Ch-VTES and 25 mm for HTACC-VTES modified fabrics) bacteria. Both modified cotton textiles showed an absorption peak at 1208 cm−1 (Si-O-C bending) in FTIR, suggesting that silane binds to the cotton substrate more firmly. The stability and longevity of the modified cotton fabrics with desired properties remain unchanged till 15 cycles of washing for the antibacterial test and the 20 cycles for the water contact angle. The fabricated textiles would be used for a wide range of uses, including medical applications as well as personal care products.

Novel Pyrimidinethione Hydrazide Divalent and Trivalent Metal Complexes for Improved High-Performance Antimicrobial and Durable UV Blocking Cellulosic Fabric

Ultraviolet (UV)-protective and antimicrobial cotton fabrics are necessary for the protection of our skin. In this article, a pyrimidinethione hydrazide (PTH) derivative ligand was complexed with Mn, Co, Ni, Cu, Zn, and Cd as divalent metals and Fe and Cr as trivalent metals to prepare highly antimicrobial and UV-blocking metal–pyrimidinethione hydrazide-modified cotton fabrics (M-PTH-C). The cotton sample treated (M-PTH) was found to show improved efficiency over pyrimidinethione hydrazide-modified cotton (PTH-C). Cadmium-PTH-C showed the highest performance of antimicrobial action against Staphylococcus aureus (Gram-positive bacteria), Escherichia Coli (Gram-negative bacteria), and Candida albicans (fungi) with zones of inhibition 31 mm, 18 mm, and 27 mm, respectively. Furthermore, all M-PTH-C samples showed no effect against Candida albicans, except Co, Ni, and Cd pyrimidinethione hydrazide-modified cotton with inhibition zones of 16 mm, 27 mm, and 22 mm. In addition, no compounds showed any activity against Aspergillus flavus except Cd-PTH-C, which gave an excellent performance, with a 33 mm inhibition zone. Furthermore, most modified cotton fabrics have excellent UV protection. Fe-PTH-C showed 113.3 as the highest Ultraviolet protection factor (UPF) compared to the other modified samples. The tensile strength test of all samples was also investigated. The values of tensile strength for the treated cotton samples are slightly affected compared to the untreated ones.

Development of Antimicrobial Microcapsules of Saffron Petal Essential Oil by Condensation Method and Its Excellent Binding on Cotton Fibers

In recent years, textiles with antimicrobial properties have attracted more and more attention. As natural antimicrobial agents, essential oils’ potential application value lies in their ability to provide textiles with antimicrobial functions. In this paper, organic solvent extraction (n-hexane, petroleum ether, ethanol) and steam distillation were used to extract saffron petal essential oil (SPEO). It was found that organic solvent extraction (ethanol) had the highest extraction rate and the most apparent bacteriostatic effect. SPEO-Ms were prepared using the composite condensation method with gelatin and chitosan. The microstructure, encapsulation efficiency, slow-release performance, infrared spectrum, and thermal stability of the SPEO-Ms were evaluated. The results showed that the microencapsulated essential oil had good bacteriostatic properties. Antimicrobial cotton fabric was prepared by impregnating microcapsules onto cotton fibers. The effects of the microcapsules’ concentration on the whiteness, air permeability, moisture permeability, and bacteriological inhibition of the fabric were investigated. The results revealed that SPEO-Ms have the potential to be used as a new antimicrobial agent in textiles.

Sustainable antibacterial cotton fabrics with in situ formed silver nanoparticles by bio-inkjet printing

A green digital printing process and innovative pretreatment combination endow sustainable, non-toxic, economical, and eco-friendly antimicrobial products. A sustainable inkjet printing technique was developed herein to fabricate antimicrobial cotton fabrics with enhanced wash-fastness properties in situ bio-synthesized with silver nanoparticles using an aqueous solution. The silver salt precursor was used to form silver nanoparticles by sustainable inkjet printing deposition. Silver salt could be dissolved in water to form green aqueous ink solutions, to eliminate nozzle clogging and simplify the deposition process. Before printing, the cotton fabrics were pretreated with biodegradable natural carbohydrate polymers, sodium alginate, and aloe vera, in concentrations of 15 g, 25 g and 30 g acting as bio-reducing agents. The formulated ink was printed via a digital printing process repeatedly to fabricate in situ biosynthesized silver nanoparticles. Green antimicrobial cotton fabrics appeared resistant to S. aureus, E. coli and C. albicans by consecutive bio-printings. Pretreating cotton fabric with sodium alginate induced higher antimicrobial properties and wash-fastness with respect to the aloe vera pretreated ones. The inhibition zone of inkjet-printed pretreated cotton fabric with sodium alginate increased from 14 mm for one layer to 17 mm for ten layers against S. aureus without yellowing on cotton fabric.

Greenly prepared antimicrobial cotton fabrics using bioactive agents from Cupressaceae pods

Antimicrobial fabrics have become essential in organizing and managing infestation and reducing odor formation by microbes. Various green sources add antimicrobial properties to fabrics, particularly cotton. However, the major problem with microbial fabrics is the reduction in antimicrobial activity after each wash. Cupressaceae pods have shown natural potential as an antimicrobial agent in herbal medicine. This study utilizes Cupressaceae for incorporating antimicrobial properties in cotton fabrics. After methanolic extraction of the Cupressaceae extract, it was applied to cotton fabrics. The application of the extract to cotton fabrics was performed by optimizing concentration, temperature and pH parameters. The extract-modified cotton showed the best performance at a 15 wt.% concentration, 140°C and pH 7.5. The treated fabrics were tested in the presence and absence of a binder using the standard washing method ISO 105-C10:2006. The mordant-treated fabric retained 16.4% more activity after 20 washes. Finally, the antimicrobial activity of the greenly developed antimicrobial cotton fabrics was checked against Staphylococcus, Escherichia coli, Bacillus and Candida albicans by using the AATCC 100-2004 test method. The study indicated that the prepared cotton fabric showed better antimicrobial activity against the earlier mentioned strains, except for C. albicans. The prepared antimicrobial fabric showed a wide range of antimicrobial activities and a lower fungal activity. Thus, the prepared fabric can be used for wound dressings, hospital staff gown material and athlete’s sportswear to prevent microbial infection.

Questioning ZnO, Ag, and Ag/ZnO nanoparticles as antimicrobial agents for textiles: Do they guarantee total protection against bacteria and SARS-CoV-2?

Coronavirus Disease 2019 (COVID-19) occasioned global economic and health systems collapse. Also, it raised several concerns about using conventional cotton fabrics for manufacturing personal protective equipment without the antimicrobial capacity to inactivate viruses, such as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its variants. Therefore, developing antimicrobial cotton fibers is crucial to avoid new global pandemics or the transmission of dangerous pathogens that remain on surfaces for long periods, especially in hospitals and medical clinics. Herein, we developed antimicrobial cotton fabrics with Ag, ZnO, and Ag/ZnO nanoparticles and evaluated their bactericidal activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), photocatalytic activity, and antiviral activity against Delta SARS-CoV-2. Although the antimicrobial fabrics are effective against these bacteria, they only reduce part of the SARS-CoV-2 virions during the first 15 min of direct contact via damage only to biological structures on the viral surface particle while the viral RNA remains intact.

Universal Preparation Strategy for Ultradurable Antibacterial Fabrics through Coating an Adhesive Nanosilver Glue.

Microbiological protection textile materials played an important role in the battle against the epidemic. However, the traditional active antimicrobial treatment of textiles suffers from narrow textile applicability, low chemical stability, and poor washability. Here, a high-strength adhesive nanosilver glue was synthesized by introducing nontoxic water-soluble polyurethane glue as a protectant. The as-prepared nanosilver glue could adhere firmly to the fiber surfaces by forming a flexible polymer film and could encapsulate nanosilver inside the glue. The as-prepared nanosilver had a torispherical structure with diameter of ~22 nm, zeta potential of −42.7 mV, and good dispersibility in water, and it could be stored for one year. Further studies indicated that the nanosilver glue had wide applicability to the main fabric species, such as cotton and polyester fabric, surgical mask, latex paint, and wood paint. The antimicrobial cotton and polyester fabrics were prepared by a simple impregnation–padding–baking process. The corresponding antimicrobial activity was positively correlated with nanosilver content. The treated fabrics (500 mg/kg) exhibited ultrahigh washing resistance (maintained over 99% antibacterial rates for 100 times of standard washing) and wear resistance (99% antibacterial rates for 8000 times of standard wearing), equivalent breathability to untreated fabric, improved mechanical properties, and good flexibility, demonstrating a potential in cleanable and reusable microbiological protection textiles.

Antimicrobial finishing of cotton fabric by atmospheric pressure plasma

In order to synthesize the antimicrobial cotton fabrics, two antimicrobial agents, 3-chloro-2-hydroxypropyltrimethyl ammonium chloride (TX-DF) and 3-(acrylamidopropyl) trimethylammonium chloride (APTAC), were grafted onto cotton fabrics by atmospheric pressure plasma treatment. Orthogonal array testing strategy (OATS) was applied to investigate the optimum treatment conditions of the atmospheric pressure plasma, including sputter-gas species, gas pressure, treatment power and time. The obtained cotton fabrics were characterized by fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and energy dispersive X-ray (EDS). And the results revealed the successful grafting of two antimicrobial agents on cotton fabrics. The antimicrobial efficiency of the plasma treated cotton fabric were studied and found that the TX-DF-treated cotton fabric inactivated 99.85% S. aureus and 99.07% E. coli O157:H7 in 30 min contact time. The cotton sample grafted with APTAC inactivated 74.6% S. aureus and 92.3% E. coli O157:H7 in 30 min. The hand feeling of the plasma treated antimicrobial cotton fabrics ware measured by PhabrOmeter system, and the result showed that the plasma treatment has little effect on hand value. Thus, the antimicrobial property of cotton fabric finished with TX-DF by the argon/oxygen-plasma techniques achieved sound effects.

Development of Wash-Durable Antimicrobial Cotton Fabrics by In Situ Green Synthesis of Silver Nanoparticles and Investigation of Their Antimicrobial Efficacy against Drug-Resistant Bacteria.

An environment friendly and wash-durable silver nanoparticle treatment of cotton fabrics was carried out by in situ reduction of silver nitrate using Azadirachta indica leaf extract. The wash durability of the silver nanoparticles treatment on the cotton fabric was improved by pretreating the fabrics by mercerization and by adopting hydrothermal conditions of 120 °C temperature and 15 psi pressure for the in situ synthesis. The silver nanoparticle treated fabrics were characterized using scanning electron microscopy, colorimetric analysis and inductively coupled plasma mass spectroscopy. The coating of silver nanoparticles was seen to be dense and uniform in the scanning electron micrographs of the treated fabrics. An evaluation of the antibacterial efficacy of the silver nanoparticle treated fabric against antibiotic-resistant Gram-positive and Gram-negative strains was carried out. The antibacterial efficacy was found to be the highest against Bacillus licheniformis, showing 93.3% inhibition, whereas it was moderate against Klebsiella pneumoniae (20%) and Escherichia coli (10%). The transmittance data of a UV spectrophotometer (290–400nm) was used for measuring the UV protection factor of the silver nanoparticle treated fabrics. All the silver nanoparticle treated fabrics showed good antimicrobial and UV protection activity. The treatment was also seen to be durable against repeated laundering. This paper contributes the first report on a novel green synthesis approach integrating mercerization of cotton fabrics and in situ synthesis of nanoparticles under hydrothermal conditions using Azadirachta indica leaf extract for improved wash durability of the multifunctional fabric.

Development of Nanocomposite based Antimicrobial Cotton Fabrics Impregnated by Nano SiO2 Loaded AgNPs Derived from Eragrostis Teff straw

ABSTRACT In the contemporary textile sector, antimicrobial fabrics have an increasing global interest. This study focused on the development of antimicrobial cotton fabrics impregnated with nanocomposite. The nanocomposite was prepared by nanoparticles of Ag loaded with nano SiO2. As a cutting-edge alternative raw material, Eragrostis teff straw was used to synthesis SiO2 nanoparticles (SiO2NPs) by sol–gel technique. Ag nanoparticles (AgNPs) were obtained via green synthesis from silver nitrate (AgNO3) using Ocimum lamiifolium plant extract as a reducing agent. Stőber method was applied to obtain SiO2 impregnated Ag nanocomposite (SiO2@AgNC). The nanocomposite was characterised by different techniques, such as FTIR, XRD, BET, and SEM. Further, SiO2@AgNC was utilised to load in cotton fabric to develop an antimicrobial fabric. The antimicrobial proficiency of developed fabrics was investigated through minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) against selected bacterial species, such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. From the results, the MIC for S. aureus, P. aeruginosa, and E. coli was found to be 0.60 mg/ml, 0.45 mg/mL, and 1.05 mg/ml, respectively. The MBC for S. aureus, P. aeruginosa, and E. coli were found to be and 0.75 mg/ml, and 1.00 mg/ml, and 2.00 mg/ml, respectively. The inferences revealed that the developed fabrics could be applied extensively including healthcare, packaging materials, protective clothing, and others.

Cotton Fabrics Decorated with Antimicrobial Ag-Coated TiO2 Nanoparticles Are Unable to Fully and Rapidly Eradicate SARS-CoV-2.

The successful development of multifunctional cotton fabrics with antimicrobial and antiviral activities is essential to prevent the proliferation of microorganisms and transmission of coronavirus virions today, especially with the emergence of new variants of SARS-CoV-2. In this work, we developed antimicrobial cotton fabrics with Ag/TiO2 nanoparticles synthesized via sonochemistry. Here, we show that more than 50% of infectious SARS-CoV-2 remain active after prolonged direct contact self-disinfecting materials capable of inhibiting the proliferation of Escherichia coli and Staphylococcus aureus. The findings bring several epidemiologic worries about using silver and TiO2 as self-disinfecting nanostructured agents to prevent coronavirus transmission.

Development of Antimicrobial Cotton Fabric Impregnating AgNPs Utilizing Contemporary Practice

Multifunctional fabrics using conventional processes have piqued increasing global interest. The focus of this experiment was to assess the modification of the cotton fabric surface by utilizing silver nanoparticles (AgNPs) and introducing functional properties along with sustainable dyeing performance. A single-jersey knitted fabric composed of cellulose-enriched 100% natural fiber (cotton) with an areal density of 172 GSM was used in this study. The standard recipe and test methods were employed. FTIR-ATR spectra were used to determine the fixing of AgNPs onto the fiber surface. A comparative assessment was conducted in response to the distribution of color, color fastness to wash, water, perspiration, rubbing, and light. Scanning electron microscopy (SEM) was used to characterize the surface of nano-Ag-deposited specimens. In terms of functional properties, antimicrobial activity was scrutinized. Our findings reveal that the nanoparticles impart remarkable antibacterial effects to cellulose-enriched fabric against S. aureus (Gram-positive) and E. coli (Gram-negative). Direct dyes were used for dyeing the proposed samples, resulting in enhanced dyeing performance. Except for light fastness, the samples dipped with AgNPs showed outstanding color levelness and color durability characteristics. The developed fabrics can be applied in a wide range of functions, including protective clothing, packaging materials, and healthcare, among others.

Grafted antimicrobial cotton fabrics with N-halamine groups via atom transfer radical polymerization

An N-halamine precursor 2-(3-(6-methyl-4-oxo-1,4-dihydropyrimidin-2-yl)ureido)ethyl methacrylate (SCMHBMA) was synthesized and grafted on cotton fabrics via atom transfer radical polymerization for antibacterial function after chlorination. The preparation and chlorinated cotton fabrics (Cotton-g-PSMA-Cl) were characterized with FTIR, XPS, SEM, and TGA. The properties of prepared Cotton-g-PSMA-Cl, including thermal property, antibacterial efficiency, durability, and stability, were systematically evaluated. The results showed that these chlorinated Cotton-g-PSMA-Cl fabrics possessed excellent antibacterial activity against E. coli. and S. aureus. After 10 washing cycles and 60 days of routine storage, active chlorine concentrations (Cl+%) were reduced only 22% and 18%, respectively, and the reduced Cl+% effectively reverted by simple rechlorination. This new N-halamine antibacterial cotton composite with superior antibacterial properties exhibited potential for future application in the long-term antibacterial field.