67 Background: Breast cancer is increasing incidence and decreasing in mortality, leading to a higher prevalence of survivors who face the consequences of the disease and its treatment. The needs of pts in different age groups may be unique. Methods: Retrospective cross-sectional analyses were performed on pts with stages 0-III breast cancer seen at Breast Cancer Supportive Care Foundation in Calgary, Canada, 2008-2016. Descriptive statistics summarized demographics. QoL data were collected using an adapted QoL Scale/Breast Cancer Patient questionnaire measuring physical, emotional, social and spiritual factors. ANOVA tested association between demographics and QoL scores. Results: 490 pts were included. Ages at diagnosis were < 40y (14.9%), 40-49y (34.2%), 50-59y (34.2%) and ≥60y (16.7%). Most pts had invasive disease (89.4%). 60% had breast conserving surgery, 45.3% mastectomy, 65.1% chemotherapy, 58% radiation therapy, 72% anti-hormonal therapy and 13.8% trastuzumab. Physical well-being: < 40y pts had less pain than others (p < 0.049). Emotional well-being: ≥60y pts reported better coping despite disease (p < 0.017), less ongoing anxiety (p < 0.02) and less stress due to changes in appearance (p < 0.006) or self-concept (p < 0.007) than others; ≥60y expressed more control in their lives (p < 0.03) than others; compared to ≥60y, < 40y pts felt less satisfied in life (p < 0.005), less supported (p < 0.02), more fearful of recurrence (p < 0.02) and second cancer (p < 0.005), more depressed (p < 0.02) and more distressed upon completion of curative treatment (p < 0.0002). Social well-being: < 49y pts had higher levels of employment interference than ≥50y pts (p < 0.002); < 40y pts felt more isolated than others (p < 0.05); < 49y pts had higher financial burden than ≥50y pts (p < 0.02); ≥60y pts had less concerns with sexuality than others (p < 0.004). Spiritual well-being: ≥60y pts participated more in religious activities (p < 0.04) and felt more hopeful (p < 0.02) than 50-59y pts. Conclusions: Different age groups have specific needs after breast cancer curative therapy. Ongoing research in survivorship care is essential to develop appropriate programs that promote comprehensive support for pts and families.