Anthropometric Parameters Research Articles

Stature estimation in male and female populations of India and Nigeria depending on other anthropometric parameters using multiple regression analysis

In cases of mass disasters, accidents, or criminal investigations where the identity of victims is unknown certain basic anthropological parameters are helpful in ascertaining these like race, sex, age and stature. Estimating stature using multiple body measurements such as shoulder breadth, foot length, thigh length, and knee height is a common approach in anthropometry and forensic anthropology. The presence of sex and population differences in anthropometric indicators allows these measurements to be used not only to estimate the stature of an individual, but also to determine sex, different races or populations based on skeletal remains. The purpose of the study is to develop and practically verify the work of regression equations for estimating stature depending on other anthropometric indicators of men and women of two ethnically diverse populations. For this study, anthropometric data were gathered from two distinct population groups: Indian (n=102) and Nigerian (n=205). Basic demographic details along with measurements of shoulder breadth, sitting shoulder height, sitting foot length, sitting knee height, and sitting thigh length were obtained using standardized techniques as per the established anthropometric protocols. Statistical analysis was performed using appropriate software packages such as SPSS, R, or SAS. The multiple regression method was used to estimate body length depending on other anthropometric indicators. As a result of the conducted multiple linear regression analysis, reliable relationships between stature and specific anthropometric measurements in Nigerian and Indian men and women were established. It was found that stature is highly likely to depend on knee height in a sitting position in Nigerian women (R2=0.531, p<0.001), as well as hip length, foot length, and shoulder height in a sitting position in Indian men (R2=0.725, p <0.001). Stature in Indian women reliably depends on hip length and foot length in a sitting position, and in Nigerian men - on hip length, foot length, shoulder width and shoulder height in a sitting position, but the regression equations have a coefficient of determination less than 0.5 (respectively, R2=0.463, p<0.001 and R2=0.405, p<0.001) and therefore do not have much significance for forensic purposes. Additional groups (30 people for each category) were used to test the obtained regression equations. The high correlation coefficients (0.6<r<0.75) observed in both test groups indicate the reliability of the regression models and the suitability of the selected anthropometric measurements for the estimation of stature in these populations. The obtained data emphasize the importance of taking into account factors specific to the population when developing regression equations for the estimation of stature and emphasize the usefulness of anthropometric measurements in predicting this indicator for different gender and demographic groups of the population, although their further verification on larger and more diverse samples is necessary.

Preventing and treating childhood obesity by sleeping better: a systematic review.

Childhood obesity represents a major public health issue worldwide. Evidence showed the need to implement prevention strategies mainly focused on lifestyle habits. Sleep hygiene is a variable of great interest and this review systematically examined the effects of sleep duration in increasing childhood obesity risk. A systematic literature review was conducted from December 2023 to February 2024. Study selection and data extraction procedures were performed in accordance with Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines and Statement, and risk of publication bias was assessed by the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies. Original works in English were eligible for review and eleven studies that met the inclusion criteria were included. Studies collected were heterogeneous in terms of duration, sample characteristics, hours of sleep manipulation, anthropometric and hematological parameters collected, therefore it was not possible to perform a meta-analysis. A narrative synthesis of the reported evidence highlighted the impact of sleep duration above all on food intake, eating habits and hormone levels and consequently on the risk of childhood obesity development. This finding suggests the need to consider sleep hygiene as a modifiable lifestyle habit like diet and physical activity, in order to early prevent childhood obesity. Poor sleep hygiene can significantly contribute to weight gain and exacerbation of metabolic disorders linked to childhood obesity. Although more rigorous studies are needed, clinicians need to be aware of the role of sleep hygiene in reducing childhood obesity risk.

Progression in central blood pressure and hemodynamic parameters and relationship with cardiovascular risk factors in a Spanish population. EVA follow-up study.

The progression of Central Blood Pressure (CBP) values and central hemodynamic parameters and its relationship with cardiovascular risk factors is quite unknown. We sought to investigate this association in a Spanish adult population without cardiovascular diseases. Prospective observational research with a five-year follow-up. Randomly sampled 501 individuals (mean age 56±14 years, 50.3% women). After five years, 480 individuals had a follow-up. Measurements taken using the SphygmoCor® (AtCor Medical Pty Ltd., Head Office,West Ryde, Australia), following all the recommendations established in the "International task force"1, giving an estimate of central blood pressure relative to measured brachial blood pressure (type 1 device). Progressions during follow-up: central systolic blood pressure (cSBP): 4.16±13.71 mmHg; central diastolic blood pressure (cDBP): 2.45±11.37 mmHg; central pulse pressure (cPP): 1.72±12.43 mmHg; pulse pressure amplification (PPA): 2.85±12.20 mmHg; ejection duration (ED): 7.00±47.87ms; subendocardial viability ratio (SEVR): -8.04±36.24%. In multiple regression analysis: cSBP positively associated with: BMI (β=0.476); waist size (β=0.159); number of cigarettes per day (β=0.192). Inversely associated with peripheral systolic blood pressure (β=-0.282). cDBP increase positively associated with number of cigarettes per day (β=0.174). Inversely associated with peripheral diastolic blood pressure (β=-0.292). cPP increase positively associated with BMI (β=0.330). Inversely associated with peripheral pulse pressure (β=-0.262). PPA increase positively associated with: BMI (β=0.276); number of cigarettes per day (β=0.281). ED progress inversely associated with basal plasma glucose (β=-0.286). All measures increased except for SEVR. Progressions in CBP and PPA were positively associated with anthropometric parameters and number of cigarettes and CBP inversely associated with peripheral blood pressure, although this association was different according to sex.

Short-term gut microbiota's shift after laparoscopic Roux-en-Y vs one anastomosis gastric bypass: results of a multicenter randomized control trial.

Roux-en-Y (RYGB) and one anastomosis gastric bypass (OAGB) represent two of the most used bariatric/metabolic surgery (BMS) procedures. Gut microbiota (GM) shift after bypass surgeries, currently understated, may be a possible key driver for the short- and long-term outcomes. Prospective, multicenter study enrolling patients with severe obesity, randomized between OAGB or RYGB. Fecal and blood samples were collected, pre- (T0) and 24months postoperatively (T1). GM was determined by V3-V4 16S rRNA regions sequencing and home-made bioinformatic pipeline based on Qiime2 plugin and R packages. To compare OAGB vs RYGB microbiota profile at T1 and its impact on metabolic and nutritional status. 54 patients completed the study, 27 for each procedure. An overall significant variation was detected in anthropometric and serum nutritional parameters at T1, with a significant, similar decrease in overall microbial alpha and beta diversity observed in both groups. An increase in relative abundances of Actinobacteria and Proteobacteria and a reduction of Bacteroidetes, no significant changes in Firmicutes and Verrucomicrobia, with an increase of the Firmicutes/Bacteroidetes ratio were observed. BMS promotes a dramatic change in GM composition. This is the first multicenter, RCT evaluating the impact of OAGB vs Roux-en-Y bypass on GM profile. The bypass technique per se did not impact differently on GM or other examined metabolic parameters. The emergence of slightly different GM profile postoperatively may be related to clinical conditions or may influence medium or long-term outcomes and as such GM profile may represent a biomarker for bariatric surgery's outcomes.

Handgrip Strength and Upper Limb Anthropometric Characteristics among Latin American Female Volleyball Players.

Background: In volleyball, the upper limb dimensions and grip strength greatly influence offensive and defensive movements during a match. However, the relationship between these parameters remains underexplored in elite female volleyball players. Objective: This study aimed to contrast the upper limb anthropometric characteristics and handgrip strength (HGS) of female elite volleyball players against a control group. Methods: Selected upper limb anthropometric parameters and maximal HGS of 42 female volleyball players and 40 non-athletes were measured. Results: Players exhibited higher values in almost all variables studied than non-athletes. The differences were statistically significant (p < 0.001) except for body mass index and elbow and wrist diameters. Players showed a moderate correlation between dominant HGS and hand parameters (length r = 0.43 and breadth r = 0.63; p < 0.05). Weak correlations were identified with height, upper arm length, elbow diameter, and hand shape index (r = 0.32 to 0.38; p < 0.05). In the non-dominant hand, a moderate correlation with handbreadth (r = 0.55, p ≤ 0.01) and weak correlations with upper arm length, wrist diameter, hand length, and hand shape index (r = 0.32 to 0.35; p ≤ 0.05) was found. Conclusions: These findings underscore the importance of the upper limb anthropometric parameters as predictors of HGS and their utility in athlete selection. Future research should investigate biomechanical factors influencing HGS and injury prevention.

Artificial neural network-based control of powered knee exoskeletons for lifting tasks: design and experimental validation

Abstract This study introduces a hybrid model that utilizes a model-based optimization method to generate training data and an artificial neural network (ANN)-based learning method to offer real-time exoskeleton support in lifting activities. For the model-based optimization method, the torque of the knee exoskeleton and the optimal lifting motion are predicted utilizing a two-dimensional (2D) human–exoskeleton model. The control points for exoskeleton motor current profiles and human joint angle profiles from cubic B-spline interpolation represent the design variables. Minimizing the square of the normalized human joint torque is considered as the cost function. Subsequently, the lifting optimization problem is tackled using a sequential quadratic programming (SQP) algorithm in sparse nonlinear optimizer (SNOPT). For the learning-based approach, the learning-based control model is trained using the general regression neural network (GRNN). The anthropometric parameters of the human subjects and lifting boundary postures are used as input parameters, while the control points for exoskeleton torque are treated as output parameters. Once trained, the learning-based control model can provide exoskeleton assistive torque in real time for lifting tasks. Two test subjects’ joint angles and ground reaction forces (GRFs) comparisons are presented between the experimental and simulation results. Furthermore, the utilization of exoskeletons significantly reduces activations of the four knee extensor and flexor muscles compared to lifting without the exoskeletons for both subjects. Overall, the learning-based control method can generate assistive torque profiles in real time and faster than the model-based optimal control approach.

A Comparison of Anthropometrics Parameters by Different Court Play Position in Girl’s Youth Volleyball

The aim of the study was to compare the anthropometrics parameters of young female volleyball players by different court play position. 52 female volleyball players (indoor court) (mean ± SD age: 15.7 ± 1.2 years) participated in the study. Players were divided based on their playing position (middle blocks, setters, liberos, and hitters (outside hitter/left side hitter and opposite hitter/right side hitter). They were examined in the field for anthropometric characteristics such as BM (mean ± SD: 61.4 ± 13.4 kg), height (mean ± SD: 163.6 ± 7.7 cm), Body Mass Index [BMI] (mean ± SD: 22.6 ± 3.1), waist circumference (mean ± SD: 70 ± 8.4 cm).All data are presented as mean ± SD, and the level of significance was set at p ≤0.05. Therefore, a parametric analysis, one-way analysis of variance (ANOVA), was used to determine significant differences among positions in anthropometric parameters.Post hoc comparison indicated that height and body mass differed significantly among most groups; however, no significant differences were found between middle blocker and setters (p = 0.20) for height. In addition, no significant differences (p &gt; 0.05) were detected between the setter and opposite hitters (p = 0.55) and between middle blocker and outside hitter (p = 0.41) for body-height. In conclusion this study indicates that significant differences exist among youth female volleyball players of different playing positions for body-mass, body-height, waist-circumference and BMI.

The association between nutritional status measured by body mass index and outcomes in the pediatric intensive care unit.

The relationship between nutritional status upon admission to a pediatric intensive care unit (PICU) and clinical outcomes remains unclear. We examined the relationship between nutrition status, as indicated by body mass index-for-age (BMI-for-age), and clinical outcomes in the PICU. In this retrospective study at a tertiary care center, records of 1,015 critically ill children and adolescents aged one month to 18 years old with available anthropometric parameters were included. The nutritional status upon admission was determined by calculating the BMI-for-age z-score using the WHO growth charts as the reference. The participants were categorized as underweight (BMI-for-age z-score < -2), normal weight (-2 ≤ BMI-for-age z-score ≤ +1), and overweight/obese (BMI-for-age z-score > +1). Multi-variate odds ratios (OR) with 95% confidence intervals (CI) were used to investigate the association between malnutrition (being underweight and overweight/obese) and odds of Prolonged PICU stay (≥7 days) and PICU mortality after controlling for descriptive characteristics, Glasgow Coma Scale score status, fluctuations in serum sodium, and acute kidney injury confounders. The proportions of patients in underweight, normal weight, and overweight/obese categories were 34.2%, 45.8%, and 20%, respectively. During the study period, 21.5% of patients had prolonged PICU stay, and 5.6% of patients in PICU died. Compared to normal-weight patients, underweight patients had higher odds of prolonged PICU stay (OR: 1.52; 95% CI: 1.05-2.22) and PICU mortality (OR: 2.12; 95% CI: 1.22-4.01). Age- and gender-stratified full-adjusted analysis showed that the increased odds of prolonged PICU stay remained significant among underweight boys and underweight individuals aged 5-19 years old. Furthermore, the increased odds of PICU mortality remained significant among underweight individuals aged 2-5 years old. However, being overweight or obese during PICU admission did not demonstrate a significant association with our outcomes in the total sample or subgroup analysis. Our findings showed that PICU patients who were underweight had higher odds of prolonged PICU stay and PICU mortality than their normal-weight counterparts. This underscores the importance of closely monitoring underweight patients in the PICU upon admission in order to improve clinical outcomes.

Effect of ethinyl estradiol/ norethisterone acetate with and without scaling on periodontal status and high-sensitivity C-reactive protein levels in women with polycystic ovarian syndrome having gingivitis: a randomized controlled trial.

Combined oral contraceptives are used for the management of hyperandrogenism and menstrual abnormalities in polycystic ovarian syndrome (PCOS). There is a dearth of literature addressing the effect of ethinyl estradiol/norethisterone acetate (EE/NETA) on gingival and systemic inflammation in these patients. This randomized trial aims to evaluate the effect of EE/NETA with and without scaling on periodontium and high sensitivity C-reactive protein (hsCRP) levels in women with PCOS having gingivitis. Women having PCOS along with gingivitis were randomly divided into two groups: Test Group (TG, n=30) received EE/NETA + scaling with oral hygiene instructions (OHI) and Control Group 1 (CG1, n=30) received EE/NETA + OHI. Another Control Group (CG2, n=30) consisting of systemically healthy females having gingivitis and who were age and BMI matched with the test group participants received scaling along with OHI. Periodontal and anthropometric parameters were measured at baseline, 3 months and 6 months follow-up. Serum hsCRP levels were also estimated. Serum hsCRP levels and periodontal parameters were significantly decreased in all the groups after 6 months (p≤0.05). The decrease in hsCRP levels was similar among the groups (p>0.05). Significantly more reduction in gingival inflammation was observed in TG compared to CG1 (p≤0.05). EE/NETA used alone and with scaling showed no detrimental effect on gingiva and could reduce systemic and gingival inflammation in women with PCOS having gingivitis.

Metabolic revitalization: exploring erythrocyte fatty acid profile following laparoscopic sleeve gastrectomy.

Obesity is linked to metabolic disorders. Bariatric surgery offers a promising therapeutic approach, but its impact on fatty acid (FA) profiles within erythrocytes and the associated clinical implications remain underexplored. This study aimed to assess changes in erythrocytes' membranes FA after Laparoscopic Sleeve Gastrectomy (LSG) and to correlate these alterations with clinical parameters. Sixty-one patients with morbid obesity undergoing LSG and 32 healthy controls were enrolled. Erythrocytes' membranes FA were analyzed using gas chromatography. Clinical parameters were assessed, including BMI, blood pressure, and multiple biochemistry markers. Bariatric intervention reduced BMI (41.1 to 32.0) and fat mass (54.1 to 35.2kg). Also, other anthropometric parameters improved significantly. Favorable changes in FA metabolism post LSG, potentially leading to a reduction in cardiovascular disease (CVD) risk, were observed. The OMEGA-3 Index (1.8 vs 3.0), and the eicosapentaenoic/arachidonic (0.1 vs 0.2) FA ratio increased after surgery. The dynamics of metabolism post-LSG, assessed by exploring the ratios of erythrocytes' FA concentration in baseline and 6 months after the surgery, with the corresponding ratios calculated for clinical parameters, evidenced the impact of linoleic (LA) on obesity reduction. The LA ratios increased along with the reduction of BMI (r=-0.32), fat mass (r=-0.39), and waist circumference (r=-0.33) proportions. The opposite relations of LA were held with Excess Weight Loss percentage (r=0.49), and Excess BMI Loss percentage (r=0.5). The study underscores distinct post-LSG changes in erythrocytes' FA profiles potentially associated with reduced weight and BMI, improved inflammatory status, and lowered CVD risk.

Nutritional disorders as a predictor of rapid diagnosis and disease progression in patients with amyotrophic lateral sclerosis

Background: One of the symptoms of amyotrophic lateral sclerosis (ALS) is progressive loss of body weight. Moreover, in various forms of ALS, regardless of the presence of dysphagia at the onset of the disease, there are similar changes in nutritional status. The problem of nutritional support in patients with ALS, as well as monitoring nutritional status over time in this group of patients remains relevant. Purpose: to evaluate the severity and rate of increase in nutritional disorders in patients with ALS and their relationship with the rate of disease progression, as well as the life expectancy of these patients. Materials and methods: The study included 49 patients diagnosed with ALS who died from 2018 to 2023. All participants underwent a neurological examination, measurement of anthropometric parameters, and laboratory blood tests; 61 % (n=30) of the patients underwent bioimpedance analysis of body composition over time. Results: The highest rate of body weight loss was recorded in the group of patients with quickly diagnosed ALS: it accounted for 1.9 (1.6; 2.2) kg/month. The highest rate of loss of skeletal muscle mass was noted in the same group of patients at 0.4 (0.38;0.46) kg/month. In the group with a quickly diagnosed disease, only 20 % of the patients underwent gastrostomy insertion; in the group with a slow diagnosis rate, 25 % of the patients underwent gastrostomy; only 50 % of the patients received special therapeutic nutrition. Conclusions: Patients with rapid disease progression have a short period of ALS diagnosis and rapidly increasing nutritional disorders, reflected in higher rates of losing weight and skeletal muscle mass. However, patients with rapid diagnosis of the disease had the lowest level of nutritional support. Lack of time to make the difficult decision to insert a gastrostomy tube and perform the necessary preoperative examination is the main reason for the low rate of gastrostomy tube placement in patients with rapidly progressing disease. In this regard, the development of new measures and algorithms for dynamic monitoring of the nutritional status of patients with ALS, as well as increasing awareness of the need for timely gastrostomy, is required. Bioimpedance analysis of body composition can be one of the methods for monitoring the patient’s nutritional status, allowing one to assess the dynamics of decrease in skeletal muscle mass as the most labile component of body composition in patients with ALS.

Features of the relationship of intestinal microbiota indicators with clinical and biochemical parameters in obese young people

BACKGROUND: The prevalence of obesity is rising dramatically worldwide. Recently, there is increasing evidence linking obesity with the functional state of the intestinal microbiota. The understanding of this relationship may provide new approaches to the treatment of obesity by manipulating the qualitative and quantitative parameters of intestinal bacterial-fungal associations.AIM: To study the features of the qualitative and quantitative composition of the colon microbiota and to evaluate associations with anamnestic, anthropometric and biochemical parameters in young obese patients.MATERIALS AND METHODS: A single-center, cross-sectional, single-stage, controlled study was conducted with the participation of 118 young people, of whom 87 were obese, and 31 people with normal body weight formed the control group. All participants underwent a biochemical blood test (total cholesterol, high-density lipoproteins, low-density lipoproteins, very low-density lipoproteins, triglycerides, uric acid, glucose, glycated hemoglobin, C-reactive protein), as well as an assessment of the state of the colon microbiota using polymerase chain reaction in real time using a set of Colonoflor-16 (premium) reagents. The Microsoft Excel 2010 and IBM SPSS Statistics 26.0 application software package was used for statistical calculations. The results were evaluated as statistically significant at a level of p&lt;0.05.RESULTS: Analyzing the result of Colonoflor-16 premium, the discrepancy between the obtained data of the control group and the reference values of the analysis was revealed. There was a clear tendency to decrease the content of Lactobacillus spp and Bifidobacterium spp in the obesity group. In addition, in comparison with the control group (10.3%), in the obesity group Fusobacterium nucleatum significantly prevailed (37.6%) (p=0.005), with a significant decrease in the bacteria Faecalibacterium prausnitzii (p=0.030), and an increase in the bacteria Prevotella spp (p=0.029). A lot of associations of representatives of the colon microbiota with the most important anamnestic, anthropometric and biochemical parameters were revealed in young obese patients.CONCLUSION: There is a redistribution of microbiota phylotypes characterized by a decrease in apathogenic microorganisms and the appearance and increase of opportunistic and pathogenic microorganisms, which generally indicates the formation of the pro-inflammatory potential of dominants and associates in young obese patients. The presence of statistically significant correlations strongly indicates of existence of close and diverse relationships between the quantitative and qualitative parameters of the microbiota and the metabolic parameters of patients.

Polycystic ovary syndrome: new and promising treatment methods

Polycystic Ovary Syndrome (PCOS) - is a polygenic endocrine disorder caused by genetic, hormonal, and epigenetic factors. The importance of addressing PCOS lies in its prevalence, affecting approximately 10 to 13% of women, as well as the associated health conditions that can have a negative impact on women's lives, including infertility, dermatological manifestations of hyperandrogenism (such as hirsutism and acne), cardiovascular pathologies, metabolic disorders, and psychoemotional disorders. Currently, many theories of the development of this disease have been proposed, and as a consequence of methods of influencing and treating it. According to the clinical recommendations of the Ministry of Health of the Russian Federation, modifying the patient's lifestyle forms the basis of comprehensive therapy. We have analyzed about 60 articles on various dietary approaches to the treatment of PCOS, sourced from PubMed, Nature Reviews, Oxford Academic, Clinical Nutrition, EJOG, ScienceDirect, and MDPI. The Mediterranean diet, the DASH diet, the ketogenic diet and the low-carb diet have proven themselves the best. Also, it's necessary to add vitamin D, E, folic acid, calcium, various pro- and prebiotics to a woman's diet. Currently, the use of inositol and GPP-1 is becoming a promising method of PCOS therapy. According to the results of the analysis, a positive effect of diet therapy on the anthropometric and biochemical parameters was noted. Based on the analysis, a positive effect of diet therapy on anthropometric and biochemical parameters has been observed. It is crucial to consider the individual characteristics of each patient and not rely solely on drug therapy when approaching the treatment of PCOS.

Clinical and Cardiometabolic Effects of Reducing Sedentary Behavior in Postmenopausal Women with Rheumatoid Arthritis.

We investigated the effects of a 4-month intervention targeting sedentary behavior on sedentary time and physical activity level, clinical parameters, cardiometabolic risk factors, inflammatory markers, and health-related quality of life in post-menopausal women with rheumatoid arthritis. This was a 4-month, parallel-group, randomized controlled trial (ClinicalTrials.gov identifier: NCT03186924). One-hundred-and-three postmenopausal rheumatoid arthritis patients were randomized (1:1) to either a newly developed intervention targeting sedentary behavior (Take a STAND for Health; TS4H) or standard of care (SOC). Sedentary behavior (primary outcome) and physical activity levels, clinical parameters, anthropometric parameters and body composition, blood samples and oral glucose tolerance test, blood pressure, muscle function, and health-related quality of life were assessed at baseline (Pre) and after 4 months (Post). Between- and within-group differences were tested using linear mixed models following the intention-to-treat principle. Total sedentary time, time in prolonged sitting bouts, standing, and stepping did not change in either group (all p ≥ 0.337). No significant between- and within-group differences were detected for any of the clinical parameters, markers of cardiometabolic health and inflammation, and health-related quality of life variables (all p ≥ 0.136). Among responders in TS4H group (those who reduced sedentary time by ≥30 min/d), Pre to Post IL-10 concentrations tended to reduce (group*time: p = 0.086; estimated mean difference [EMD]: -12.0 pg/mL [-23.5 to -0.6], p = 0.037), and general health (group*time: p = 0.047; EMD: 10.9 A.U. [-1.1 to 22.9], p = 0.086) and overall physical health tended to improve (group*time: p = 0.067; EMD: 7.9 A.U. [-0.9 to 16.6], p = 0.089). TS4H did not change sedentary behavior, physical activity levels, clinical, cardiometabolic, inflammatory or health-related quality of life outcomes. However, TS4H tended to reduce IL-10 levels and improve health-related quality of life in responders.

Anthropometric Predictors of Heart Rate Variability in Overweight Individuals: A Comparative Study.

Introduction The autonomic nervous system is crucial in regulating cardiovascular function. Heart rate variability (HRV) analysis, a non-invasive method to assess autonomic function, reflects the beat-to-beat variations in heart rate and provides insights into the dynamic interplay between sympathetic and parasympathetic influences on the cardiovascular system. In this study, we aimed to find the HRV parameters in overweight individuals by comparing different anthropometric parameters, including body mass index (BMI), percentage body fat (%BF), waist circumference (WC), and waist-hip ratio (WHR). Method The descriptive cross-sectional study was conducted on 132 healthy first-year MBBS students (82 males and 50 females), aged between 17 and 23 years. Anthropometric parameters (BMI, %BF, WC, WHR) and HRV were recorded for the participants. The HRV parameters were analyzed for either gender. A student 't' test was used to test the difference between groups BMI <25 kg/m2 and = or >25 kg/m2,and a p-value less than 0.05 was taken to be statistically significant. The Pearson correlation coefficient was used to show the relationship between HRV parameters and BMI, %BF, WC, and WHR as the independent variables. Result A total of 132healthy individuals participated in the study, including 82 males and 50 females. The participants had a mean age of 18.72 ± 0.98 years. Our results suggest that while WC and WHR can be used alongside BMI to indicate sympathetic hyperactivity in males, BMI remains the most significant predictor in females. We found gender-specific differences in high-frequency (HF) related to various anthropometric measures, but these differences were not statistically significant. The low-frequency:high-frequency (LF/HF) ratio exhibits strong positive correlations with all measured anthropometric parameters, suggesting that increased values in BMI, %BF, WC, and WHR are associated with greater sympathetic involvement. Conclusion WC and WHR, alongside BMI, are reliable indicators of heightened sympathetic activity in both males and females. These measures should be utilized to assess healthy individuals for the early diagnosis of dysautonomia, disrupt the cycle of sympathetic overactivity, and prevent cardiovascular complications. All these anthropometric parameters are valuable for indicating sympathovagal balance, making them essential tools in the proactive management of autonomic dysfunction and associated health risks.

Electrodiagnostic Findings of Median Nerve Motor and Sensory Conduction in Neurological Asymptomatic Newly Diagnosed Patients with Hypothyroidism

BACKGROUND: The influence/impact of thyroid hormones on peripheral nervous system has still not been thoroughly/substantially studied/examined. Neurographic studies, which measure motor and sensory nerve conduction along with F-wave, have an important role in diagnosing diseases of the peripheral nerves since electrophysiological sings of neuropathy can be detected even in subclinical state/cases. AIM: The aims of this study were to assess the neurophysiological parameters of the median nerve by electrodiagnostic measurements using electromyoneurogaphy (EMNG) in the region of radiocarpal joint in patients with newly diagnosed and medically untreated primary hypothyroidism who had no symptoms and signs of peripheral nerve damage/injury/lesion. Furthermore, it was our aim to make an insight of the possible early detection of the latent damage of peripheral nervous system in untreated hypothyroidism. MATERIAL AND METHODS: This was a prospective clinical study that comprised 78 subjects/patients according to inclusion criteria, divided into two groups: one with primary hypothyroidism and the other group involving euthyroid subjects. Thyroid status was examined in each subject; anthropometric parameters were analyzed, and electromyoneurographic imaging (EMNG) of hand median nerve was realized. RESULTS: Of the total number of 78 subjects included in the study, 58 (74.36%) had hypothyroidism and 20 were euthyroid subjects (25.64%). The calculated mean levels of thyroid status parameters in hypothyroid patients, TSH, aTPO and FT4, were 6.19±1.85 mIU/L, 872.22±296.66 U/mL and 0.78±0.11 ng/dL, respectively. In euthyroid patients, the mean levels of TSH, aTPO and FT4 were 0.27±0.08 mIU/L, 31.2071±5.65 U/mL and 1.31±0.25 ng/dL, respectively. Statistically significant differences were obtained between hypothyroid and euthyroid subjects regarding: age (p=0.0147, r=0.3239), body weight (p=0.0441, r= -0.531), body mass index (p=0.0050, r= -0.301), WHO classification for BMI (p=0.0032, r= -0.250), TSH (p&lt;0.0001, r=-0.309), aTPO (p&lt;0.0001, r=0.5554) and FT4 (p&lt;0.0001, r= -0.317). In the group of 58 hypothyroid subjects, 38 (65.52%) were women and 20 (34.48%) were men. A strong correlation and significant statistical difference were registered in EMNG pathological findings in patients with pathologic BMI and with mild predilection for the sensory part of the median nerve. Of the 58 hypothyroid patients, EMNG pathologic findings were present in 18 that, in terms of their features, indicated a distal lesion of the median nerve. These 18 subjects had an increased body mass index (30.83±5.65 kg/m2). CONCLUSIONS: Discovery, definition and explanation of etiopathogenic nodes in peripheral nervous system diseases will require extensive and multidisciplinary strategies in the next decades. These complex conditions, in our opinion, will claim a steady/a step-by-step/ approach to the problems, as well as consistency and symmetry in the design and methodology of the research procedures.

Morphofunctional indicators of the body students of the medical university

Introduction. The period of adolescence accounts for the completion of the growth processes of the body, and the beginning of stabilization of functional indicators, which, as more plastic factors, are more sensitive to environmental conditions. Measuring, evaluating, and predicting morphofunctional parameters of the body of medical university students, taking into account regional standards of physical development, is one of the priorities of modern medicine and scientific research in general.The aim of the study is to study the features of anthropometric and functional characteristics, vegetotype of medical university students in comparison with the current regional standard.Materials and methods. Anthropometric and functional parameters were measured in 300 medical students (77 males, 223 females), aged 19,1±0,88 years.Results. It is shown that anthropometric characteristics of students significantly exceed the regional standard, in boys it is body length (p&lt;0,01), and weight-height ratio (p&lt;0,05), in girls it is body length, chest circumference and weight-height ratio (p&lt;0,01). Cardiointervalography parameters revealed 4,01 % vagotonics, 88,33 % eutonics and 7,62 % sympathotonics, a significant difference (p&lt;0,01) was also found in linear cardiointervalogram parameters in cohorts of these vegetotypes. Functional indices in absolute terms revealed compliance with the regional standard only in vital capacity of lungs, carpal dynamometry is significantly lower than the standard, in girls (p&lt;0,01), boys (p&lt;0,05), haemodynamics in terms of diastolic blood pressure and heart rate significantly (p&lt;0,01) exceeds the reference values. Integral functional indices: vital index, vegetative index, minute volume of respiration differ significantly by sex (p&lt;0,05); Kerdo index, minute volume of blood circulation showed a significant difference by vegetotype (p&lt;0,05); pulse pressure showed a significant difference by sex and vegetotype (p&lt;0,01).Conclusion. The studies showed statistically significant excesses relative to the regional standard in young men in body length (p&lt;0,01) and mass-height ratio (p&lt;0,05), in chest circumference in girls (p&lt;0,01); in diastolic blood pressure and heart rate in boys and girls (p&lt;0,01). Absolute and integral indices of cardio-respiratory system are significantly higher in sympathotonics than in vagotonics. Young men, relative to girls, demonstrate higher absolute, linear values of cardiointervalogram (p&lt;0,01), in the whole population these indices are within the range of norm of the regional standard. Among students the majority 88,33 % have normotonic type of ANS. The obtained results, in our opinion, show the need for systematic monitoring of objective morphofunctional state of modern youth.

Hypothyroidism in Metabolic Syndrome.

Metabolic syndrome (MetS) and hypothyroidism are well-established forerunners of atherogenic cardiovascular disease (CVD). It is possible that patients suffering from both these disease entities may have a compounded risk. This study aimed at determining the prevalence of hypothyroidism in MetS. This cross-sectional study was conducted from September 2017 to August 2018 in the department of medicine at a tertiary care hospital in Northern India. Ethical approval was obtained from the institutional ethical committee. The study subjects consisted of 157 patients with MetS, the diagnosis of which was based on the International Diabetes Federation criteria. After a detailed history and physical examination, relevant investigations including complete thyroid profile were done. The data were analyzed using appropriate statistical tests (P < 0.05). In our study, the age of subjects ranged between 14 and 92 years, with a mean ± standard deviation of 48.1 ± 17.01 years. There were more females than males with a male-to-female ratio of 1:1.3. The prevalence of hypothyroidism was 46.5%. Hypothyroidism was more common in females (58.9%) as compared to males (41.1%). Patients with hypothyroidism had significantly higher body weight and body mass index (BMI) in comparison to euthyroid patients. The rest of the anthropometric parameters were comparable. Waist circumference and BMI of overt hypothyroid patients were found to be higher as compared to subclinical hypothyroid patients. Total cholesterol and triglyceride were significantly higher (P = 0.001 and P < 0.001, respectively), while high-density lipoprotein levels were significantly lower in patients with hypothyroidism than the euthyroid group (P < 0.001). Hypothyroidism, especially subclinical hypothyroidism, is a common endocrine disorder in patients with MetS. As MetS and hypothyroidism are independent risk factors for CVD, hence there is a need for screening for hypothyroidism and the treatment of the same can be beneficial in reducing the cardiovascular morbidity and mortality in patients with MetS.

Using anthropometric parameters to predict insulin resistance among patients without diabetes mellitus

Anthropometric parameters are widely used in the clinical assessment of hypertension, type 2 diabetes, and cardiovascular disease. However, few studies have compared the association between different anthropometric parameters and insulin resistance (IR). This study was aimed at investigating the relationship between 6 indicators, including body mass index (BMI), calf circumference (CC), arm circumference (AC), thigh circumference (TC), waist circumference (WC), waist-height ratio (WHtR), and IR. Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) was used to measure IR. Weighted linear regression was used to assess the relationship between different parameters and IR. The receiver operating characteristic curve (ROC) was employed to compare the strength of the relationship between different anthropometric parameters and IR. A total of 8069 participants were enrolled in our study, including 4873 without IR and 3196 with IR. The weighted linear regression results showed that BMI, CC, AC, TC and WC were significantly correlated with IR, except WHtR. After adjusting for multiple confounding factors, we found that BMI, AC and WC were significantly positively correlated with IR, while TC was significantly negatively correlated with IR. Logistic regression results showed that a larger TC was associated with a decreased risk of IR. In addition, BMI and WC had similar areas under the curve (AUC: 0.780, 95% CI 0.770–0.790; AUC: 0.774, 95% CI 0.763–0.784, respectively), which were higher than TC and AC (AUC: 0.698, 95% CI 0.687–0.710, AUC: 0.746, 95% CI 0.735–0.757, respectively). To our knowledge, this is the first study to report a negative correlation between TC and IR among patients without diabetes mellitus. Therefore, TC may be a new tool to guide public health and a clinical predictor of IR in non-diabetic patients.

Evaluating the Association of Anthropometric Indices With Total Cholesterol in a Large Population Using Data Mining Algorithms.

Unbalanced levels of serum total cholesterol (TC) and its subgroups are called dyslipidemia. Several anthropometric indices have been developed to provide a more accurate assessment of body shape and the health risks associated with obesity. In this study, we used the random forest model (RF), decision tree (DT), and logistic regression (LR) to predict total cholesterol based on new anthropometric indices in a sex-stratified analysis. Our sample size was 9639 people in which anthropometric parameters were measured for the participants and data regarding the demographic and laboratory data were obtained. Aiding the machine learning, DT, LR, and RF were drawn to build a measurement prediction model. Anthropometric and other related variables were compared between both TC <200 and TC ≥200 groups. In both males and females, Lipid Accumulation Product (LAP) had the greatest effect on the risk of TC increase. According to results of the RF model, LAP and Visceral Adiposity Index (VAI) were significant variables for men. VAI also had a stronger correlation with HDL-C and triglyceride. We identified specific anthropometric thresholds based on DT analysis that could be used to classify individuals at high or low risk of elevated TC levels. The RF model determined that the most important variables for both genders were VAI and LAP. We tend to present a picture of the Persian population's anthropometric factors and their association with TC level and possible risk factors. Various anthropometric indices indicated different predictive power for TC levels in the Persian population.