This research aimed to assess the structural and morphological variations in shape and size of the condylar head with age and gender in a sample of Saudi population. Radiographic evaluation of the bilateral condylar heads shape and size were measured on CBCT images and statistically analyzed using SPSS 22.0. There was a considerable variation in shape and size of the condyles among males and females with age. The shapes of the condyles varied between convex, round, flat and angled. The most predominant and statistically significant shape in both right and left condyles was convex (P < 0.05). Whereas, there was no significant difference according to shape between the right and left condyles among males and females with increased age. Using the student t-test; there was a statistically significant difference in the ML dimensions between the right (P = 0.006) and left condyle (P = 0.040) between males and females and with increased age (P = 0.00) but with no statistically significant difference between the AP dimensions of the right and left condyle with gender and age (P > 0.05). The morphology of the mandibular condyle was subject to significant linear age-related changes in shape and size with no significant gender differences. There was an obvious decrease in length and width with age in both genders. Condylar length was significantly greater among males and gradually decreased in size with age. Keywords: Mandibular condyle, CBCT, shape, size, Anteroposterior (AP), Mediolateral (ML)