Anterior-posterior Shear Research Articles

A New Methodology for the Accurate Measurement of Tibiofemoral Kinematics in Human Cadaveric Knees: An Evaluation of the Anterior-Posterior Laxity Pre- and Post-Cruciate Ligament Resection.

Anterior-posterior (AP) stability is an important measure of knee performance after total knee arthroplasty (TKA). To improve the stabilizing effect of implants designed to compensate for the loss of the cruciate ligaments, it is important to understand the tibiofemoral contact situation within the native ligamentous situation of the knee and how it changes after cruciate ligament resection. This in vitro study introduces a new approach to accurately measure the tibiofemoral kinematics in a six-degrees-of-freedom joint motion simulator by tracking landmark-based coordinate systems and their corresponding bone geometries. The tibiofemoral contact situation was investigated by projecting the medial and lateral flexion facet centers onto the tibial plateau under AP shear forces across various flexion angles in thirteen knees. Tests were conducted pre- and post-cruciate ligament resection. Post-cruciate ligament resection, the femoral condyles shifted closer to or even exceeded the posterior border of the tibial plateau, but only slightly closer to the anterior border. This study presents a new methodology for measuring the tibiofemoral kinematics that can be applied to multiple loading profiles. It provides a basis for further investigations, including passive or active muscle forces, to enhance the design of total knee protheses and improve surgical outcomes.

Musculoskeletal spine modeling in large patient cohorts: how morphological individualization affects lumbar load estimation.

Introduction: Achieving an adequate level of detail is a crucial part of any modeling process. Thus, oversimplification of complex systems can lead to overestimation, underestimation, and general bias of effects, while elaborate models run the risk of losing validity due to the uncontrolled interaction of multiple influencing factors and error propagation. Methods: We used a validated pipeline for the automated generation of multi-body models of the trunk to create 279 models based on CT data from 93 patients to investigate how different degrees of individualization affect the observed effects of different morphological characteristics on lumbar loads. Specifically, individual parameters related to spinal morphology (thoracic kyphosis (TK), lumbar lordosis (LL), and torso height (TH)), as well as torso weight (TW) and distribution, were fully or partly considered in the respective models according to their degree of individualization, and the effect strengths of these parameters on spinal loading were compared between semi- and highly individualized models. T-distributed stochastic neighbor embedding (T-SNE) analysis was performed for overarching pattern recognition and multiple regression analyses to evaluate changes in occurring effects and significance. Results: We were able to identify significant effects (p < 0.05) of various morphological parameters on lumbar loads in models with different degrees of individualization. Torso weight and lumbar lordosis showed the strongest effects on compression (β ≈ 0.9) and anterior-posterior shear forces (β ≈ 0.7), respectively. We could further show that the effect strength of individual parameters tended to decrease if more individual characteristics were included in the models. Discussion: The induced variability due to model individualization could only partly be explained by simple morphological parameters. Our study shows that model simplification can lead to an emphasis on individual effects, which needs to be critically assessed with regard to in vivo complexity. At the same time, we demonstrated that individualized models representing a population-based cohort are still able to identify relevant influences on spinal loading while considering a variety of influencing factors and their interactions.

Biomechanical comparative study on external fixators of new configurations in the treatment of Tile C pelvic injury

To compare the biomechanical properties of several anterior pelvic ring external fixators with two new configurations in the treatment of Tile C pelvic fractures, in order to evaluate the effectiveness of the new configurations and provide a reference for their clinical application. A finite element model of a Tile C pelvic ring injury (unilateral longitudinal sacral fracture and ipsilateral pubic fracture) was constructed. The pelvis was fixed with iliac crest external fixator (IC), anterior inferior iliac spine external fixator (AIIS), combination of IC and AIIS, combination of anterior superior iliac spine external fixator (ASIS) and AIIS, and S1 sacroiliac screw in 5 types of models. The stability indices of the anterior and posterior pelvic rings under vertical longitudinal load, left–right compression load and anterior–posterior shear load were quantified and compared. In the simulated bipedal standing position, the results of the vertical displacement of the midpoint on the upper surface of the sacrum are consistent with the displacement of the posterior rotation angle, and the order from largest to smallest is IC, AIIS, ASIS + AIIS, IC + AIIS and S1 screw. The longitudinal displacement of IC is greater than that of the other models. The displacements of ASIS + AIIS and IC + AIIS are similar and the latter is smaller. In the simulated semi-recumbent position, the vertical displacement and posterior rotation angle displacement of the midpoint on the upper surface of the sacrum are also consistent, ranking from large to small: IC, AIIS, ASIS + AIIS, IC + AIIS and S1 screw. Under the simulated left–right compression load state, the lateral displacements of the highest point of the lateral sacral fracture end are consistent with the highest point of the lateral pubic fracture end, and the order from large to small is S1 screw, IC, AIIS, ASIS + AIIS and IC + AIIS, among which the displacements of S1 screw and IC are larger, and the displacements of ASIS + AIIS and IC + AIIS are similar and smaller than those of other models. The displacements of IC + AIIS are smaller than those of ASIS + AIIS. Under the simulated anterior–posterior shear load condition, the posterior displacements of the highest point of the lateral sacral fracture end and the highest point of the lateral pubic fracture end are also consistent, ranking from large to small: IC, AIIS, ASIS + AIIS, IC + AIIS and S1 screw. Among them, the displacements of IC and AIIS are larger. The displacements of ASIS + AIIS and IC + AIIS are similar and the latter are smaller. For the unstable pelvic injury represented by Tile C pelvic fracture, the biomechanical various stabilities of the combination of IC and AIIS are superior to those of the external fixators of conventional configurations. The biomechanical stabilities of the combination of ASIS and AIIS are also better than those of the external fixators of conventional configurations, and slightly worse than those of the combination of IC and AIIS. Compared with sacroiliac screw and conventional external fixators, the lateral stabilities of IC + AIIS and ASIS + AIIS are particularly prominent.

Biomechanical analysis of complications following T10-Pelvis spinal fusion: A population based computational study

Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are challenging complications of long fusion constructs for the treatment of adult spinal deformity. The objective of this study is to understand the biomechanical stresses proximal to the upper instrumentation of a T10-pelvis fusion in a large patient cohort. The pre-fusion models were subject-specific thoracolumbar spine models that incorporate the height, weight, spine curvature, and muscle morphology of 250 individuals from the Framingham Heart Study Multidetector CT Study. To create post-fusion models, the subject-specific models were further modified to eliminate motion between the intervertebral joints from T10 to the pelvis. OpenSim analysis tools were used to calculate the medial lateral shear force, anterior posterior shear force, and compressive force on the T9 vertebra during the static postures. Differences between pre-fusion and post-fusion T9 biomechanics were consistent between increased segmental mobility and unchanged segmental mobility conditions.For all static postures, compression decreased (p < 0. 0005). Anterior-posterior shear force significantly increased (p < 0. 0005) during axial twist and significantly increased (p < 0. 0005) during trunk flexion. Medial lateral shear force significantly increased (p < 0. 0005) during axial twist. This computational study provided the first use of subject-specific models to investigate the biomechanics of long spinal fusions. Patients undergoing T10-Pelvis fusion were predicted to have increased shear forces and decreased compressive force at the T9 vertebra, independent of change in segmental mobility. The computational model shows potential for the investigation of spinal fusion biomechanics to reduce the risk of PJK or PJF.

Invasiveness of decompression surgery affects modeled lumbar spine kinetics in patients with degenerative spondylolisthesis.

Introduction: The surgical treatment of degenerative spondylolisthesis with accompanying spinal stenosis focuses mainly on decompression of the spinal canal with or without additional fusion by means of a dorsal spondylodesis. Currently, one main decision criterion for additional fusion is the presence of instability in flexion and extension X-rays. In cases of mild and stable spondylolisthesis, the optimal treatment remains a subject of ongoing debate. There exist different opinions on whether performing a fusion directly together with decompression has a potential benefit for patients or constitutes overtreatment. As X-ray images do not provide any information about internal biomechanical forces, computer simulation of individual patients might be a tool to gain a set of new decision criteria for those cases. Methods: To evaluate the biomechanical effects resulting from different decompression techniques, we developed a lumbar spine model using forward dynamic-based multibody simulation (FD_MBS). Preoperative CT data of 15 patients with degenerative spondylolisthesis at the level L4/L5 who underwent spinal decompression were identified retrospectively. Based on the segmented vertebrae, 15 individualized models were built. To establish a reference for comparison, we simulated a standardized flexion movement (intact) for each model. Subsequently, we performed virtual unilateral and bilateral interlaminar fenestration (uILF, bILF) and laminectomy (LAM) by removing the respective ligaments in each model. Afterward, the standardized flexion movement was simulated again for each case and decompression method, allowing us to compare the outcomes with the reference. This comprehensive approach enables us to assess the biomechanical implications of different surgical approaches and gain valuable insights into their effects on lumbar spine functionality. Results: Our findings reveal significant changes in the biomechanics of vertebrae and intervertebral discs (IVDs) as a result of different decompression techniques. As the invasiveness of decompression increases, the moment transmitted on the vertebrae significantly rises, following the sequence intact ➝ uILF ➝ bILF ➝ LAM. Conversely, we observed a reduction in anterior-posterior shear forces within the IVDs at the levels L3/L4 and L4/L5 following LAM. Conclusion: Our findings showed that it was feasible to forecast lumbar spine kinematics after three distinct decompression methods, which might be helpful in future clinical applications.

Evaluation of in-shoe plantar pressure and shear during walking for diabetic foot ulcer prevention.

To investigate reliability and changes of in-shoe plantar pressure and shear during walking at three cadences with two insole designs. This was a precursor to the investigation of plantar loading in people with diabetes for potential foot ulcer prevention. A sensorised insole system, capable of measuring plantar pressure and shear at the heel, fifth metatarsal head (5MH), first metatarsal head (1MH) and hallux, was tested with ten healthy participants during level walking. Reliability was evaluated, using intra-class correlation coefficient (ICC), while varying the cadences and insole types. Percentage changes in pressure and shear relative to values obtained at self-selected cadence with a flat insole design were investigated. Mean±standard deviation of maximum pressure, medial-lateral and anterior-posterior shear of up to 380±24kPa, 46±2kPa and -71±4kPa, respectively, were measured. The ICC in ranges of 0.762-0.973, 0.758-0.987 and 0.800-0.980 were obtained for pressure, anterior-posterior and medial-lateral shear, respectively. Opposite anterior-posterior shear directions between 5MH and 1MH (stretching), and between 1MH and hallux (pinching) were observed for some participants. Increasing cadence increased pressure and anterior-posterior shear (by up to +77%) but reduced medial-lateral shear at the heel and hallux (by up to -34%). Slower cadence increased anterior-posterior shear (+114%) but decreased medial-lateral shear (-46%) at the hallux. The use of a flexible contoured insole resulted in pressure reduction at the heel and 5MH but an increase in anterior-posterior shear at the heel (+69%) and hallux (+75%). The insole system demonstrated good reliability and is comparable to reported pressure-only systems. Pressure measurements were sensitive to changes in cadence and insole designs in ways that were consistent with the literature. However, our plantar shear showed localised shear changes with cadences and insoles for the first time, as well as stretching and pinching effects on plantar tissue. This opens new possibilities to investigate plantar tissue viability, loading characteristics and orthotic designs aimed towards foot ulcer prevention.

Poster 128: The Effect of Meniscotibial Ligament Disruption and Repair on Posterior Medial Meniscal Root Forces

Objectives: Meniscal injuries occur in as many as 1% of active people, and while outcomes for tears at the posterior medial meniscal root (PMMR) are well cited, the risk factors for injury have room for greater understanding. Incidence of disruption to the meniscotibial ligament (MTL) is correlated to occurrence of PMMR tears, suggesting that disruption to the MTL may increase forces at the PMMR and put the PMMR at greater risk of injury. The effect of an MTL disruption and repair on three-dimensional forces at the PMMR is unknown. The purpose of this study was to determine if MTL insufficiency alters forces at the PMMR., if a tenodesis procedure can restore PMMR forces to that of an MTL intact state, and to determine how knee flexion angle impacts PMMR root forces in the MTL intact and cut states. We hypothesize that all shear forces will increase following MTL disruption. Methods: Ten fresh-frozen cadaveric knees (Average age: 53.2 years) were tested in three conditions (Intact, MTL Cut, MTL Tenodesis). Specimens were dissected down to the knee capsule with ligaments intact. A 3D load cell construct (Figure 1) was installed inside the tibia such that 3D forces of the PMMR could be measured when the joint was loaded. Each specimen was mounted to a materials testing machine (Instron) via a custom fixture that allowed the specimen flexion angle to be changed in 30 degree increments. The specimen was first loaded to 500 N of compression with 0 N-m of torque, then to 5 N-m of internal torque with 50 N of compression, and finally to 5 N-m of external torque with 50 N of compression. 3D forces at the PMMR were recorded for all loading sequences, and the process was repeated for each flexion angle (0°, 30°, 60°, and 90°). PMMR forces along each axis (compression- tension, anterior-posterior shear, and medial-lateral shear) were compared across MTL testing states across flexion angles using linear mixed modelling. Results: When the joint was loaded in compression, MTL Cut state significantly increased compression of the PMMR (p = 0.0368), and the Tenodesis state did not significantly restore tension-compression forces of the PMMR (Intact→Tenodesis: p = 0.008)(Figure 1). When the joint was loaded in external rotation, the MTL Cut State significantly increased compression (p &lt; 0.0001), significantly decreased anterior shear (p = 0.0003), and, in high flexion angles, significantly decreased ML shear forces of the PMMR (Figure 1). The Tenodesis state did not significantly restore tension-compression (Intact→Tenodesis: p &lt; 0.0001) or AP forces (Intact→Tenodesis: p = 0.0002) of the PMMR (Figure 1). Conclusions: The key finding of this study is that MTL disruption increases compression forces and decreases AP shear forces seen at the root when the joint is loaded in compression and external rotation. These findings indicate that the intact MTL protects the PMMR from compression and shear loads during movements where the joint is loaded in compression and external rotation, movements that are clinically reported to put the knee joint at risk of PMMR injury. The authors believe these relationships are observed because the MTL may play a role in maintaining meniscal hoop stresses, which converts joint compression loads into tension and shear forces along the meniscal attachment points. When the MTL is disrupted, the other meniscal attachment points, the PMMR included, see elevated compression loads as a result. This is the first study to measure 3D forces at the PMMR, a necessary capability to assess PMMR injury risk. It is notable that the tenodesis procedure performed in this study did not restore PMMR forces. Future studies should develop improved centralization or tenodesis procedures to better restore PMMR forces and decrease likelihood for PMMR injury after MTL disruption.

FULLY CHARACTERIZING SPINAL LOAD DISPLACEMENT BEHAVIOUR USING VISCOELASTIC MODELS

Lower back pain (LBP) is a global problem. Countless in vitro studies have attempted to understand LBP and inform treatment protocols such as disc replacement devices (DRDs). A common method of reporting results is applying a linear fit to load-displacement behaviour, reporting the gradient as the specimen stiffness in that axis. This is favoured for speed, simplicity and repeatability but neglects key aspects including stiffening and hysteresis. Other fits such as polynomials and double sigmoids better address these characteristics, but solution parameters lack physical representation. The aim of this study was to implement an automated method to fit spinal load-displacement behaviour using viscoelastic models.Six porcine lumbar spinal motion segments were dissected to produce isolated disc specimens. These were potted in Wood's metal, ensuring the disc midplane remained horizontal, sprayed with 0.9% saline and wrapped in saline-soaked tissue and plastic wrap to prevent dehydration. Specimens were tested using the University of Bath spine simulator operating under position control with a 400N axial preload.Specimens were approximated using representative viscoelastic elements. These models were constructed in MATLAB Simulink R2020b using the SimScape library. Solution coefficients were determined by minimizing the sum of squared errors cost function using a non-linear least squares optimization method.The models matched experimental data well with a mean % difference in model and specimen enclosed area below 6% across all axes. This indicates the ability of the model to accurately represent energy dissipated. The final models demonstrated reduced RMSEs factors of 3.6, 1.1 and 9.5 smaller than the linear fits for anterior-posterior shear, mediolateral shear and axial rotation respectively.These nonlinear viscoelastic models exhibit significantly increased qualities of fit to spinal load-displacement behaviour when compared to linear approximations. Furthermore, they have the advantage of solution parameters which are directly linked to physical elements: springs and dampers. The results from this study could be instrumental in improving the design of DRDs as a mechanism for treating LBP.

A Wearable Insole System to Measure Plantar Pressure and Shear for People with Diabetes

Pressure coupled with shear stresses are the critical external factors for diabetic foot ulceration assessment and prevention. To date, a wearable system capable of measuring in-shoe multi-directional stresses for out-of-lab analysis has been elusive. The lack of an insole system capable of measuring plantar pressure and shear hinders the development of an effective foot ulcer prevention solution that could be potentially used in a daily living environment. This study reports the development of a first-of-its-kind sensorised insole system and its evaluation in laboratory settings and on human participants, indicating its potential as a wearable technology to be used in real-world applications. Laboratory evaluation revealed that the linearity error and accuracy error of the sensorised insole system were up to 3% and 5%, respectively. When evaluated on a healthy participant, change in footwear resulted in approximately 20%, 75% and 82% change in pressure, medial-lateral and anterior-posterior shear stress, respectively. When evaluated on diabetic participants, no notable difference in peak plantar pressure, as a result of wearing the sensorised insole, was measured. The preliminary results showed that the performance of the sensorised insole system is comparable to previously reported research devices. The system has adequate sensitivity to assist footwear assessment relevant to foot ulcer prevention and is safe to use for people with diabetes. The reported insole system presents the potential to help assess diabetic foot ulceration risk in a daily living environment underpinned by wearable pressure and shear sensing technologies.

Direct measurement of three-dimensional forces at the medial meniscal root: A validation study

The posterior medial meniscal root (PMMR) experiences variable and multiaxial forces during loading. Current methods to measure these forces are limited and fail to adequately characterize the loads in all three dimensions at the root. Our novel technique resolved these limitations with the installation of a 3-axis sensing construct that we hypothesized would not affect contact mechanics, would not impart extraneous loads onto the PMMR, would accurately measure forces, and would not deflect under joint loads. Six cadaveric specimens were dissected to the joint capsule and a sagittal-plane, femoral condyle osteotomy was performed to gain access to the root. The load sensor was placed below the PMMR and was validated across four tests. The contact mechanics test demonstrated a contact area precision of 44 mm2 and a contact pressure precision of 5.0 MPa between the pre-installation and post-installation states. The tibial displacement test indicated an average bone plug displacement of < 1 mm in all directions. The load validation test exhibited average precision values of 0.7 N in compression, 0.5 N in tension, 0.3 N in anterior-posterior shear, and 0.3 N in medial–lateral shear load. The bone plug deflection test confirmed < 2 mm of displacement in any direction when placed under a load. This is the first study to successfully validate a technique for measuring both magnitude and direction of forces experienced at the PMMR. This validated method has applications for improving surgical repair techniques and developing safer rehabilitation and postoperative protocols that decrease root loads.

Reverse total shoulder glenoid component inclination affects glenohumeral kinetics during abduction: a cadaveric study.

Optimal implant placement in reverse total shoulder arthroplasty (rTSA) remains controversial. Specifically, the optimal glenoid inclination is unknown. Therefore, a cadaveric shoulder simulator with 3-dimentional human motion specific to rTSA was used to study joint contact and muscle forces as a function of glenoid component inclination. Eight human cadaver shoulders were tested before and after rTSA implantation. Scapular plane abduction kinematics from control subjects and those with rTSA drove a cadaveric shoulder simulator with 3-dimentional scapulothoracic and glenohumeral motion. Glenoid inclination varied from -20° to +20°. Outputs included compression, superior-inferior (S/I) shear, and anterior-posterior shear forces from a 6° of freedom load cell in the joint, and deltoid and rotator cuff muscle forces. Data were evaluated with statistical parametric mapping and t-tests. Inferior glenoid inclination (-) reduced S/I shear by up to 125% relative to superior inclination, with similar compression to the neutral condition (0°). Superior inclinations (+) increased the S/I shear force by approximately the same magnitude, yet decreased compression by 25% in the most superior inclination (+20°). There were few differences in deltoid or rotator cuff forces due to inclination. Only the middle deltoid decreased by approximately 7% for the most inferior inclination (-20°). Compared with native shoulders, the neutral (0°) rTSA inclination showed reduced forces of 30%-75% in the anterior deltoid and a trend toward decreased forces in the middle deltoid. Force demands on the rotator cuff varied as a function of elevation, with a trend toward increased forces in rTSA at peak glenohumeral elevation. Inferior inclination reduces superior shear forces, without influencing compression. Superior inclination increased S/I shear, while decreasing compression, which may be a source of component loosening and joint instability after rTSA. Inferior inclination of the rTSA glenoid may reduce the likelihood of glenoid loosening by reducing the magnitude of cyclic shear and compressive loading during arm elevation activities, although this may be altered by specific-subject body habitus and motion. These factors are especially important in revision rTSA or glenoid bone grafting where there is already a 3-fold increase in glenoid baseplate loosening vs. primary rTSA.

Anatomic total shoulder glenoid component inclination affects glenohumeral kinetics during abduction: a cadaveric study.

Although typically favorable in outcome, anatomic total shoulder arthroplasty (aTSA) can require long-term revision. The most common cause for revision is glenoid loosening, which may result from eccentric cyclic forces and joint translations. "Rocking" of the glenoid component may be exacerbated by the joint geometry, such as glenoid inclination and version. Restoration of premorbid glenoid inclination may be preferable, although laboratory and computational models indicate that both superior inclination and inferior inclination have benefits. This discrepancy may arise because previous studies were limited by a lack of physiological conditions to test inclination. Therefore, a cadaveric shoulder simulator with 3-dimensional human motion was used to study joint contact and muscle forces with isolated changes in glenoid inclination. Eight human cadaveric shoulders were tested before and after aTSA. Scapular-plane abduction kinematics from human subjects were used to drive a cadaveric shoulder simulator with 3-dimensional scapulothoracic and glenohumeral motion. Glenoid inclination was varied from -10° to +20°, whereas compressive, superior-inferior shear, and anterior-posterior shear forces were collected with a 6-df load cell during motion. Outputs also included muscle forces of the deltoid and rotator cuff. Data were evaluated with statistical parametric mapping repeated-measures analysis of variance and t tests. Inferior glenoid inclination (-10°) reduced both compressive and superior-inferior shear forces vs. neutral 0° inclination by up to 40%, and even more when compared with superior inclination (P<.001). Superior inclinations (+10° and +20°) tended to increase deltoid and rotator cuff forces vs. neutral 0° inclination or inferior inclination, on the order of 20%-40% (P≤.045). All force metrics except anterior-posterior shear were lowest for inferior inclination. Most aTSA muscle forces for neutral 0° inclination were not significantly different from native shoulders and decreased 45% and 15% in the posterior deltoid and supraspinatus, respectively (P≤.003). Joint translations were similar to prior reports in aTSA patients and did not differ between any inclinations or compared with native shoulders. Joint reaction forces were similar to those observed in human subjects with instrumented aTSA implants, providing confidence in the relative magnitude of our results. Inferior inclination reduces overall forces in the shoulder. Superior inclinations increase the muscle effort required for the shoulder to achieve similar motion, thus increasing the forces exerted on the glenoid component. These results suggest that a preference toward aTSA glenoid components in inferior inclination may reduce the likelihood of glenoid loosening by reducing excessive muscle and joint contact forces.

Validation of a Patient-Specific Musculoskeletal Model for Lumbar Load Estimation Generated by an Automated Pipeline From Whole Body CT.

Background: Chronic back pain is a major health problem worldwide. Although its causes can be diverse, biomechanical factors leading to spinal degeneration are considered a central issue. Numerical biomechanical models can identify critical factors and, thus, help predict impending spinal degeneration. However, spinal biomechanics are subject to significant interindividual variations. Therefore, in order to achieve meaningful findings on potential pathologies, predictive models have to take into account individual characteristics. To make these highly individualized models suitable for systematic studies on spinal biomechanics and clinical practice, the automation of data processing and modeling itself is inevitable. The purpose of this study was to validate an automatically generated patient-specific musculoskeletal model of the spine simulating static loading tasks. Methods: CT imaging data from two patients with non-degenerative spines were processed using an automated deep learning-based segmentation pipeline. In a semi-automated process with minimal user interaction, we generated patient-specific musculoskeletal models and simulated various static loading tasks. To validate the model, calculated vertebral loadings of the lumbar spine and muscle forces were compared with in vivo data from the literature. Finally, results from both models were compared to assess the potential of our process for interindividual analysis. Results: Calculated vertebral loads and muscle activation overall stood in close correlation with data from the literature. Compression forces normalized to upright standing deviated by a maximum of 16% for flexion and 33% for lifting tasks. Interindividual comparison of compression, as well as lateral and anterior–posterior shear forces, could be linked plausibly to individual spinal alignment and bodyweight. Conclusion: We developed a method to generate patient-specific musculoskeletal models of the lumbar spine. The models were able to calculate loads of the lumbar spine for static activities with respect to individual biomechanical properties, such as spinal alignment, bodyweight distribution, and ligament and muscle insertion points. The process is automated to a large extent, which makes it suitable for systematic investigation of spinal biomechanics in large datasets.

From Stoop to Squat: A Comprehensive Analysis of Lumbar Loading Among Different Lifting Styles.

Lifting up objects from the floor has been identified as a risk factor for low back pain, whereby a flexed spine during lifting is often associated with producing higher loads in the lumbar spine. Even though recent biomechanical studies challenge these assumptions, conclusive evidence is still lacking. This study therefore aimed at comparing lumbar loads among different lifting styles using a comprehensive state-of-the-art motion capture-driven musculoskeletal modeling approach. Thirty healthy pain-free individuals were enrolled in this study and asked to repetitively lift a 15 kg-box by applying 1) a freestyle, 2) a squat and 3) a stoop lifting technique. Whole-body kinematics were recorded using a 16-camera optical motion capture system and used to drive a full-body musculoskeletal model including a detailed thoracolumbar spine. Continuous as well as peak compressive, anterior-posterior shear and total loads (resultant load vector of the compressive and shear load vectors) were calculated based on a static optimization approach and expressed as factor body weight (BW). In addition, lumbar lordosis angles and total lifting time were calculated. All parameters were compared among the lifting styles using a repeated measures design. For each lifting style, loads increased towards the caudal end of the lumbar spine. For all lumbar segments, stoop lifting showed significantly lower compressive and total loads (−0.3 to −1.0BW) when compared to freestyle and squat lifting. Stoop lifting produced higher shear loads (+0.1 to +0.8BW) in the segments T12/L1 to L4/L5, but lower loads in L5/S1 (−0.2 to −0.4BW). Peak compressive and total loads during squat lifting occurred approximately 30% earlier in the lifting cycle compared to stoop lifting. Stoop lifting showed larger lumbar lordosis range of motion (35.9 ± 10.1°) than freestyle (24.2 ± 7.3°) and squat (25.1 ± 8.2°) lifting. Lifting time differed significantly with freestyle being executed the fastest (4.6 ± 0.7 s), followed by squat (4.9 ± 0.7 s) and stoop (5.9 ± 1.1 s). Stoop lifting produced lower total and compressive lumbar loads than squat lifting. Shear loads were generally higher during stoop lifting, except for the L5/S1 segment, where anterior shear loads were higher during squat lifting. Lifting time was identified as another important factor, considering that slower speeds seem to result in lower loads.

Anteroposterior shear stiffness of the upper thoracic spine at quasi-static and dynamic loading rates-Anin vitro biomechanical study.

To evaluate the biomechanical properties of the upper thoracic spine in anterior-posterior shear loading at various displacement rates. Thesedata broadenour understanding of thoracic spine biomechanics and inform efforts to model the spine and spinal cord injuries. Seven T1-T2 thoracic functional spinal units were loaded non-destructively by a pure shear force up to 200 N, starting from a neutral posture. Tests were run in both posterior and anterior directions, at displacement rates of 1, 10, and 100 mm/s. The three-dimensional motion of the specimen was recorded at 1000 Hz. Individual and averaged load-displacement curves were generated and specimen stiffnesses were calculated. Due to a nonlinear response of the specimens, stiffness was defined separately for both the lower half and the upper half of the specimen range of motion. Specimens were significantly stiffer in the anterior direction than in the posterior direction, across all rates. At low displacements, the anterior stiffness averaged 230 N/mm, 76% higher than the low displacement posterior stiffness of 131 N/mm. At high displacements, anterior stiffness averaged 258 N/mm, 51% stiffer than the high displacement posterior stiffness of 171 N/mm. Shear displacement rate had a small effect on the load response, with the 100 mm/s rate causing a mildly stiffer response at low displacements in the anterior direction. Overall, the load-displacement response exhibited pseudo-quadratic behavior at 1 and 10 mm/s but became more linear at 100 mm/s. The shear stiffness in the upper thoracic spine is greatest in the anterior loading direction, being 51%-76% greater than posterior, most likely due to facet interactions. The effect of the shear displacement rate is low.

The Influence of Simulated Low Speed Vehicle Impacts and Posture on Passive Intervertebral Mechanics.

An in vitro biomechanics investigation exposing porcine functional spinal units (FSUs) to sudden impact loading although in a flexed, neutral, or extended posture. To investigate the combined effect of impact severity and postural deviation on intervertebral joint mechanics. To date, no in vitro studies have been conducted to explore lumbar tissue injury potential and altered mechanical properties from exposure to impact forces. Typically, after a motor vehicle collision, the cause of a reported acute onset of low back pain is difficult to identify, with potential soft tissue strain injury sites including the intervertebral disc, facet joint and highly innervated facet joint capsule ligament. Seventy-two porcine functional spinal units (36 C34, 36 C56), consisting of 2 adjacent vertebrae, ligaments, and the intervening intervertebral disc were included in the study. Each specimen was randomized to 1 of 3 experimental posture conditions (neutral, flexed, or extended) and assigned to 1 of 3 impact severities representing motor vehicle accident accelerations (4 g, 8 g, and 11 g). Before impact (pre) and after impact (post) flexion-extension and anterior-posterior shear neutral zone testing was completed. A significant two-way interaction was observed between pre-post and impact severity for flexion-extension neutral zone length and stiffness and anterior-posterior shear neutral zone length and stiffness. This was a result of increasedneutral zone range and decreased neutral zone stiffness pre-post for the highest impact severity (11 g), regardless of posture. Functional spinal units exposed to the highest severity impact (11 g) had significant neutral zone changes, with increases in joint laxity in flexion-extension and anterior-posterior shear and decreased stiffness, suggesting that soft tissue injury may have occurred. Despite observed main effects of impact severity, no influence of posture was observed.Level of Evidence: N/A.

Exploring the influence of impact severity and posture on vertebral joint mechanics in an in-vitro porcine model

To date, no in vitro studies have been conducted to explore lumbar soft tissue injury potential and altered mechanical properties from exposure to impact forces. After a motor vehicle collision (MVC), the cause of reported acute onset low back pain is difficult to associate with potential soft tissue strain injury sites including the facet joint and innervated facet joint capsule ligament (FJC). Thus, the purpose of this investigation was to quantify intervertebral anterior-posterior (AP) translation and facet joint capsule strain under varying postures and impact severities. Seventy-two porcine spinal units were exposed to three levels of impact severity (4 g, 8 g, 11 g), and posture (Neutral, Flexion, Extension). Impacts were applied using a custom-built impact track that replicated parameters experienced in low to moderate speed rear-end MVCs. Flexion-extension and anterior-posterior shear neutral zone testing were completed prior to impact. AP intervertebral translation and the strain tensor of the facet capsule ligament were measured during impacts. A significant main effect of collision severity was observed for peak AP intervertebral translation (4 g—2.8 ±0.53 mm; 8 g—6.4 ±2.9 mm; 11 g—8.3 ±0.45 mm) and peak FJC shear strain (2.37% strain change from 4 g to 11 g impact severity). Despite observed main effects of impact severity, no influence of posture was observed. This lack of influence of posture and small FJC strain magnitudes suggest that the FJC does not appear to undergo injurious or permanent mechanical changes in response to low-to-moderate MVC impact scenarios.

Biomechanical joint loading mechanism of Tai Chi gait in individuals with knee osteoarthritis: A pilot simulation study

ObjectivesTai Chi (TC) has shown beneficial effects on joint function in knee osteoarthritis (OA). Biomechanical mechanisms of knee joint contact load (JCL) and muscle activations during TC are less understood. The purpose of this biomechanical simulation study was to examine JCL of TC gait, the most common used TC from and its causal interactions with muscle activations in knee OA. DesignSix knee OA and five healthy participants were recruited. Their full body motion of TC gait was collected. The JCL and muscle forces were quantified using a musculoskeletal simulation approach based on collected kinematics and kinetics. The JCL and muscle activations were compared between knee OA and healthy control group. In addition, the muscle contributions to the JCL were determined and compared between the two groups. ResultsKnee OA subjects had lower peak anterior-posterior shear forces and higher lateral shear forces than healthy control subjects during TC gait. Knee OA subjects also showed higher activations of knee flexor muscles than control subjects. Both knee extensor and flexors of the knee OA group were contributing to JCL and in the control group mainly the knee extensors. ConclusionsOur simulation results showed the JCL, muscle forces profiles, and muscle contributions to the JCL during TC gait in knee OA. The findings of this study provided a direct scientific link between JCL and muscle forces during TC gait in knee OA. This would allow us to develop more effective TC interventions for knee OA in the future.

Influence of saddle height in 3D knee loads commuter cyclists: A statistical parametric mapping analysis

ABSTRACT This study used a statistical parametric mapping method to compare temporal patterns knee joint loads and moments in cyclists pedalling using different saddle heights. Ten recreational cyclists pedalled using three saddle heights (Preferred, High and Low) during a single session. High and Low saddle heights were determined based on dynamically measured knee flexion angles (±10° from their Preferred height). 3D angles for the hip and knee and knee moments and forces were computed using a musculoskeletal model driven by 3D full-body motion and pedal forces. Knee flexion angles presented significant differences between saddle heights for the full crank cycle, without differences for hip adduction/abduction. Patellofemoral force was less for the Preferred compared to the High and Low saddle heights and for the High compared to the Low saddle heights between ~70-160° of the crank cycle. Right tibiofemoral anterior-posterior shear force was reduced for the Preferred compared to the Low saddle heights, without significant effects for the left tibiofemoral joint (p = 0.29–1.00). Large differences in temporal patterns for knee flexion due to changes in saddle height were followed by differences in patellofemoral force mostly when low force magnitudes were being transmitted between the femur and the patella.

Development of a Full Flexion 3D Musculoskeletal Model of the Knee Considering Intersegmental Contact During High Knee Flexion Movements.

A musculoskeletal model of the right lower limb was developed to estimate 3D tibial contact forces in high knee flexion postures. This model determined the effect of intersegmental contact between thigh-calf and heel-gluteal structures on tibial contact forces. This model includes direct tracking and 3D orientation of intersegmental contact force, femoral translations from in vivo studies, wrapping of knee extensor musculature, and a novel optimization constraint for multielement muscle groups. Model verification consisted of calculating the error between estimated tibial compressive forces and direct measurements from the Grand Knee Challenge during movements to ∼120° of knee flexion as no high knee flexion data are available. Tibial compression estimates strongly fit implant data during walking (R2 = .83) and squatting (R2 = .93) with a root mean squared difference of .47 and .16 body weight, respectively. Incorporating intersegmental contact significantly reduced model estimates of peak tibial anterior-posterior shear and increased peak medial-lateral shear during the static phase of high knee flexion movements by an average of .33 and .07 body weight, respectively. This model supports prior work in that intersegmental contact is a critical parameter when estimating tibial contact forces in high knee flexion movements across a range of culturally and occupationally relevant postures.