Anterior Movement Research Articles

Regional associations between inspiratory tongue dilatory movement and genioglossus activity during wakefulness in people with obstructive sleep apnoea.

Inspiratory tongue dilatory movement is believed to be mediated via changes in neural drive to genioglossus. However, this has not been studied during quiet breathing in humans. Therefore, this study investigated this relationship and its potential role in obstructive sleep apnoea (OSA). During awake supine quiet nasal breathing, inspiratory tongue dilatory movement, quantified with tagged magnetic resonance imaging, and inspiratory phasic genioglossus EMG normalised to maximum EMG were measured in nine controls [apnoea-hypopnea index (AHI) ≤5 events/h] and 37 people with untreated OSA (AHI >5 events/h). Measurements were obtained for 156 neuromuscular compartments (85%). Analysis was adjusted for nadir epiglottic pressure during inspiration. Only for 106 compartments (68%) was a larger anterior (dilatory) movement associated with a higher phasic EMG [mixed linear regression, beta=0.089, 95% CI [0.000, 0.178], t(99)=1.995, P=0.049, hereafter EMG↗/mvt↗]. For the remaining 50 (32%) compartments, a larger dilatory movement was associated with a lower phasic EMG [mixed linear regression, beta=-0.123, 95% CI [-0.224, -0.022], t(43)=-2.458, P=0.018, hereafter EMG↘/mvt↗]. OSA participants had a higher odds of having at least one decoupled EMG↘/mvt↗ compartment (binary logistic regression, odds ratio [95% CI]: 7.53 [1.19, 47.47] (P=0.032). Dilatory tongue movement was minimal (>1 mm) in nearly all participants with only EMG↗/mvt↗ compartments (86%, 18/21). These results demonstrate that upper airway dilatory mechanics cannot be predicted from genioglossus EMG, particularly in people with OSA. Tongue movement associated with minimal genioglossus activity suggests co-activation of other airway dilator muscles. KEY POINTS: Inspiratory tongue movement is thought to be mediated through changes in genioglossus activity. However, it is unknown if this relationship is altered by obstructive sleep apnoea (OSA). During awake supine quiet nasal breathing, inspiratory tongue movement, quantified with tagged magnetic resonance imaging (MRI), and inspiratory phasic genioglossus EMG normalised to maximum EMG were measured in four tongue compartments of people with and without OSA. Larger tongue anterior (dilatory) movement was associated with higher phasic genioglossus EMG for 68% of compartments. OSA participants had an ∼7-times higher odds of having at least one compartment for which a larger anterior tongue movement was not associated with a higher phasic EMG than controls. Therefore, higher genioglossus phasic EMG does not consistently translate into tongue dilatory movement, particularly in people with OSA. Large dilatory tongue movements can occur despite minimal genioglossus inspiratory activity, suggesting co-activation of other pharyngeal muscles.

Assessment of Nasal Septum Change after Le Fort I Osteotomy Using Cone Beam Computed Tomography.

Le Fort I osteotomy (LF-IO) is widely used for the correction of dentofacial deformities, which may cause changes in the postoperative nasal septum (NS). The objective of this study was to evaluate the effects of LF-IO on the NS deviation and to determine whether the NS was affected by differences in the direction of maxilla movement. A retrospective study including 57 patients who underwent LF-IO and received cone beam computed tomography (CBCT) preoperatively and 6-12months postoperative evaluation was performed. The NS angle of each patient was measured both pre- and postoperatively in the two coronal sections (nasion and ostium levels). The patients were divided into five paired groups and calculated. Group 1 to 4 were divided depending on the differences in the direction of maxilla movement (Group 1. Impaction ≥ 5mm vs. Impaction < 5mm; Group 2. Anterior movement vs. Non-anterior movement; Group 3. Impaction symmetry vs. Impaction asymmetry; and Group 4. Impaction vs. Inferior repositioning). Group 5 was divided as One-piece osteotomy vs. Multi-segmental osteotomy. The mean NS angles at both nasion and ostium levels of all patients were significant increased after LF-IO. However, there were no statistical significant differences of the five paired groups. LF-IO osteotomy influenced increasing of the NS deviation at both the nasion and ostium levels. However, differences in the direction of the maxilla movement and maxilla segmentation showed no statistically significant changes.

Predicting the Potential Complications of Lateral Column Lengthening: A Cadaveric Biomechanical Study

Category: Hindfoot; Other Introduction/ Purpose: Lateral column lengthening calcaneus osteotomy is a common procedure used to treat flatfoot deformity. However, the incidence of subtalar joint impingement and sinus tarsi pain presents a concern related to this treatment. The hypothesis of this study was with opening of the osteotomy, the anterior fragment of the calcaneus anterior process moves anteriorly, while the posterior fragment simultaneously moves posteriorly which can compromise the outcome as well as cause subtalar joint impingement. The goal of this study was to observe movements of the anterior and posterior fragments with an osteotomy of different sizes. Methods: Eight fresh frozen cadaveric feet were used. A vertical calcaneus osteotomy was designed 1.5cm posterior to the calcaneocuboid joint. Optical markers were attached on each side of the osteotomy to measure movements of the anterior and posterior segments during the lengthening procedure. Three more markers were placed for reference purposes with one on the lateral process of the talus, one on the table, and one on the base of the 3rd metatarsal (Figure 1). Following the osteotomy 4mm, 6mm, 8mm, 10mm and 12mm of lengthening was obtained for each specimen using a lamina spreader. The exact lengthening achieved was measured with a micro-caliper. Movements of the anterior and posterior fragments were recorded using a Sentech model STC-MBCM401U3V camera and calculated with MaxTRAQ motion analysis software. Mixed linear regression analyses were performed using R Studio. Results: With the open osteotomy, the anterior fragment moved anteriorly, while the posterior fragment moved posteriorly (Table 1, 2). The anterior movement was larger than the posterior one. There was no difference in the amount of anterior movements during each attempted 2mm lengthening, however, the amount of the posterior movement peaked at 6mm-8 mm and went down at 8mm-10mm and 10mm-12mm, which was caused by subtalar joint impingement and limited the posterior excursion. Starting at 6mm lengthening there was a linear regression relationship between the anterior &amp; posterior movement and the lengthening (anterior movement = -4.80 + 1.06 × Lengthening of the Lateral Column, posterior Movement = -1.26 + 0.22 × Lengthening of the Lateral Column) (Figure 2,3). 1mm lengthening induced 1.06mm anterior (p &lt; 0.05), and 0.22mm posterior shift (p &lt; 0.05). Conclusion: Lateral lengthening causes the calcaneus to move both anteriorly and posteriorly which not only compromises the power of the procedure, but also can cause subtalar impingement. The findings of this study provide our colleagues with more insight into the correlation between the size of the lengthening, results, and potential complications.

New Nitinol-based Thermomechanically Adjustable IOL Technology.

To evaluate the feasibility of new adjustable intraocular lens (IOL) technology. The foldable adjustable IOL consists of a nitinol mechanism placed in a haptic-optic cradle. Heating actuators on the nitinol mechanism with a continuous green laser achieve controlled movement of the mechanism and optic. Activation occurs in controlled steps: rotation in 1-degree steps over 360 degrees, and anterior posterior movement in 0.25-diopter (D) steps with a range of +1.50 D. The IOL was tested in vitro and in vivo in a rabbit eye. Foldability and unfolding were demonstrated through a 2.6-mm cartridge. The adjustable lens mechanism was successfully tested in vitro and in vivo. Activation resulted in a change in optic position relative to the haptics and the capsular bag. Activation of the lever and ratchet mechanism showed radial advancement of the IOL clockwise and counterclockwise. In vivo rotatory movement was achieved after activation by the argon laser at 1 week after implantation. Anterior to posterior movement was accomplished by activating the circular spring actuator mechanism in the laboratory model. Uneventful folding and unfolding were performed. A new adjustable IOL with a mechanism that responds in measured steps had been shown to move as planned after activation by argon laser. This was successful in the laboratory in both radial and anterior posterior movement. The radial movement was also proven in vivo in an animal model. Further refinement of the prototype is currently being undertaken. [J Refract Surg. 2023;39(10):662-667.].

Quantifying maxillary anterior tooth movement in digital orthodontics: Does the choice of the superimposition software matter?

To compare the agreement between predetermined angular and linear tooth movement measurements processed with three digital model registration software packages. Twenty maxillary intraoral pretreatment scans of patients undergoing clear aligner therapy were randomly selected. Digital setups were generated using OrthoAnalyzer Clear Aligner Studio software to serve as the reference standard. Both pretreatment scans and setups were converted to STL files and exported to Geomagic, OrthoAnalyzer-Model Set Compare, and Compare model registration software packages. The amount of tooth movement of the maxillary incisors and canines was calculated in six degrees of freedom. Statistical significance of the obtained results was expressed at P < 0.01 to account for multiple comparisons. The maxillary central incisors showed the highest agreement for torque and rotation as measured by all software programs. Lateral incisors showed the least agreement in linear movements as measured by Geomagic and Compare, and for tip as measured by Geomagic and OrthoAnalyzer. Maxillary canines had the highest agreement for all linear movements as measured by Geomagic and Compare, and tip as measured by Geomagic and OrthoAnalyzer. Geomagic showed excellent agreement for all measurements except for torque, whereas Compare showed excellent agreement only for rotation and linear measurements. OrthoAnalyzer showed moderate agreement for all measurements except for rotation, which showed good agreement. Maxillary central incisor measurements showed higher agreement compared with measurements of the maxillary lateral incisors and canines. Although none of the software showed poor agreement, Geomagic seemed to have the highest accuracy.

A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review.

Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, rachitic rosary, tetany and so on. Here we present a case of 12-year-old girl affected by early-onset periodontitis accompanied with vitamin D deficiency. A 12-year-old girl with gingival redness, bleeding associated with tooth brushing, and mandibular anterior teeth movement, with difficulty in mastication for the past 2 months. There is no relevant family history or special systemic disease history. The serological microelement test showed vitamin D levels were significantly lower than normal range. Immunological test showed abnormal CD4+/CD8+(CD3+CD4+/CD3+CD8+) ratio as well. Based on the clinical and serological findings, this patient was ultimately diagnosed with early-onset periodontitis accompanied with vitamin D deficiency. The main treatments for this patient were 3-fold: periodontal therapy, vitamin D supplement and oral hygiene instructions. Following 1-year therapy, periodontal conditions recovered and became stable. And serological vitamin D levels returned to normal range. The case of interest serves as an important reminder to clinicians, that the early-onset periodontitis may be associated with micronutrients abnormalities, and early-diagnosis and treatment could avoid the body heathy disorders.

Transapical beating-heart septal myectomy for recurrent left ventricular outflow tract obstruction after septal reduction therapy in hypertrophic obstructive cardiomyopathy.

We present a case of a 58-year-old man for surgical myectomy due to recurrent left ventricular outflow tract (LVOT) obstruction, who had prior transaortic septal myectomy and embolization of the septal branch. On admission, transthoracic echocardiography showed a typical hypertrophic obstructive cardiomyopathy (HOCM) with asymmetric septal hypertrophy, significant LVOT obstruction, and severe mitral regurgitation (MR) due to the systolic anterior movement (SAM) of the anterior mitral valve leaflet. We performed a novel procedure of the transapical beating-heart septal myectomy (TA-BSM), following which the LVOT obstruction was resolved. And a decreased grade of SAM and a reduction in the severity of MR were observed.

Conventional Twin-Block Versus Cervical Headgear and Twin-Block Combination: Therapeutic Effects on the Craniofacial Structures in Growing Subjects.

To compare the short-term effects of the conventional twin-block (TB) appliance and the cervical headgear TB (CHG-TB) appliance on craniofacial structures. The retrospective controlled study examined lateral cephalograms taken from 46 growing subjects. Individuals were divided into two groups according to the treatment. Group I consisted of 15 individuals (9 girls, 6 boys, mean age: 12.34±1.23 years) treated with the TB appliance and Group II consisted of 16 individuals (9 girls, 7 boys) treated with the CHG-TB appliance (mean age: 12.50±1.30 years). To distinguish the treatment effects of these appliances on growth, a control group of 15 untreated individuals (9 girls, 6 boys, mean age: 11.82±1.16 years) was included from the archives. Significant improvements were found in the interdental and maxillo-mandibular measurements in the treatment groups (p<0.001). Significant differences were observed in the SNA, SN/PP, and SN/GoGn values in the CHG-TB group compared to other groups (p<0.05). The mandible showed a significant downward movement in both treatment groups compared with the control group (p<0.001), while the change in SNB angle was statistically significant only in the TB group compared to the control group (p<0.05). Lower incisors showed significant proclination only in the TB group (p<0.05). The CHG-TB appliance was found to be more effective in limiting maxillary growth and preventing lower incisor proclination compared with the TB appliance, whereas the TB appliance was more effective in anterior mandibular movement.

Condylar Changes Following Mandibular Setback Using Manual Guidance

The purpose of this retrospective study was to analyze changes in the position of the condyles following mandibular setback surgery with manual guidance. The study included 28 patients with mandibular prognathism who underwent mandibular setback surgery using manual guidance with a bioabsorbable mesh for mandibular fixation, and changes in the position of the center of the condylar head were compared at three time points: before surgery (T0), within 1 week after surgery (T1), and 6 months after surgery (T2). The results showed significant lateral, anterior, and inferior movements of the condyle at T1 compared to T0, with an average movement of 0.66 ± 0.84 mm along the x-axis, −1.27 ± 0.82 mm along the y-axis, and −0.20 ± 0.69 mm along the z-axis, with a 1.77 ± 0.87 mm linear distance (p &lt; 0.05). At T2, the condylar position had mainly changed inferiorly along the y-axis (−0.17 ± 0.48 mm) (p &lt; 0.05) compared to that at T0. The change in the position along the x-axis (−0.14 ± 0.57 mm), z-axis (−0.05 ± 0.68 mm), and linear distance (0.85 ± 0.57 mm) at T2 was not significantly different from that in the condylar position at T0 (p &gt; 0.05). The study suggests that significant anterior–lateral–inferior condylar movement occurs within 1 week after mandibular setback surgery using manual guidance, but the condyle returns to its original position over time, which is clinically acceptable.

Differences in the effects of orthodontic treatment on airway-craniocervical functional environment in adult and adolescent patients with skeletal class II high-angle: a retrospective pilot study

IntroductionThis retrospective cohort study aimed to compare the change in upper airway and craniocervical posture after orthodontic treatment between adolescent and adult patients with Class II high-angle malocclusion.MethodsA total of 12 adolescent (mean ± standard deviation age = 13.0 ± 2.0 years) and 12 adult patients with Class II high-angle malocclusion (mean ± standard deviation age = 23.7 ± 6.4 years) were selected in this study. The lateral cephalograms and cone beam computed tomography images of adolescent and adult patients were taken before and after treatment, which can be employed to evaluate the variables of craniofacial morphology, upper airway, and craniocervical posture through paired t tests, respectively. An independent sample t test was performed to observe the differences between two groups after orthodontic intervention. For adults and adolescents, the correlation between craniofacial morphology, upper airway, and craniocervical posture was determined through Pearson correlation analysis.ResultsIn all subjects, the improvements in vertical and sagittal facial morphology after treatment were observed. Anterior and inferior movements of the hyoid bone, an increase of upper airway dimension, posterior tipping of the head and a reduction of cervical inclination in the lower and middle segments post-treatment were identified in adolescence (P < 0.05). Adults displayed anterior movements of the hyoid bone, whereas no significant difference was observed in upper airway dimension and craniocervical posture (P < 0.05). Notable differences were identified in the change of hyoid position and airway volume between two groups (P > 0.05). Mandibular plane inclination, growth pattern, occlusal plane inclination, and chin position were all significantly correlated with craniocervical posture in adolescent patients. Besides, the mandibular growth pattern and chin position in adult patients were significantly correlated with craniocervical posture (P < 0.05).ConclusionsOrthodontic treatment is capable of enhancing the facial profile of patients with skeletal class II high-angle while improving their upper airway morphology and craniocervical posture, where adolescents and adults differ substantially in that the former exhibit a more favorable alteration in the airway-craniocervical functional environment.

Cruciate-Retaining Total Knee Arthroplasty: Current Concepts Review.

Posterior cruciate-retaining (CR) total knee arthroplasty for osteoarthritis of the knee is a popular implant choice. At present, there is no consensus on whether sacrifice or retention of the posterior cruciate ligament (PCL) offers superior outcomes. This review explores the current literature available on CR total knee arthroplasty (TKA). PubMed was searched by keyword to find relevant articles for inclusion. Additional sources came from article references and joint registry reports. CR design knees have distinct kinematic gait patterns from posterior-stabilizing (PS) knees and exhibit paradoxical anterior femoral movement with less femoral rollback. While CR implants offer less flexion than PS designs, the difference is not clinically detectable as clinical scores are similar in the short and long term. CR implants have better long-term survival compared to PS knees, likely due to lower risk of aseptic loosening. CR total knee arthroplasties also have shorter operating times and lower risk of peri-prosthetic fractures. Because the CR implant is unconstrained, there may be an increased risk of instability compared to PS designs, but the literature is mixed. Overall, the current literature supports the continued use of CR TKAs due to their lower risk of complications, durability, and demonstrated equivalence in function to posterior-substituting models.

Findings of a videofluoroscopic swallowing study in patients with dysphagia.

Swallowing examination is crucial in patients with dysphagia. We aimed to compare qualitative and quantitative videofluoroscopic swallowing study (VFSS) results to provide reference for standardizing quantitative parameters. In total, 117 patients with dysphagia were included, 38 with Parkinson's disease and 39 and 40 in convalescence following cerebral hemorrhage and infarction. VFSS was both qualitatively and quantitatively analyzed. A significant difference of Oral transit time was found between the oral motor function grades (p < 0.001), also was swallowing reaction times found between swallowing reaction duration grades (p < 0.001), and soft palate lift duration between the soft palate lift grades (p < 0.001). Superior hyoid bone movement (p < 0.001), anterior hyoid bone movement (p < 0.001), hyoid pause time (p < 0.001), and hyoid movement duration (p = 0.032) had significant differences between the hyoid laryngeal complex movement grades, as did the pharyngeal cavity transit time among the cricopharyngeal muscle opening duration grades (p < 0.001). The laryngeal vestibule closure duration differed among the glottic closure grades (p < 0.001). No statistically significant difference in upper esophageal sphincter opening diameter (p = 0.682) or duration (p = 0.682) among the cyclopharyngeal muscle opening duration grades. The pharyngeal area at rest did not significantly differ among the different vallecular residue (p = 0.202) and pyriform sinus residue (p = 0.116) grades. Several quantitative parameters can reflect the swallowing assessment process well. Further optimization of quantitative parameters is recommended.

How cervical curvature changes after ACAF and ACDF: a radiological retrospective study.

To assess changes in cervical curvature and demonstrate the feasibility of using ACAF technology to restore lordosis, imaging data from patients undergoing multilevel ACAF and ACDF surgeries were retrospectively analyzed. Forty-seven patients receiving multilevel ACAF and ACDF were included in the study. Total cervical curvature and anterior, middle, and posterior column curvature, spinal canal diameter, cervical range of motion, and surgical complications were measured and analyzed by non-parametric or chi-square tests before and after surgery. The Spearman correlation between imaging data was analyzed. Compared with ACDF, the operation time of the ACAF group was longer, the cervical motion was larger, the median and change value of the middle column curvature was larger, and the change value of the posterior column curvature was smaller (P < 0.05). The postoperative differences in cervical lordosis angle, vertebral canal diameter, and middle and posterior column curvature in the ACAF group were significantly greater than those in the ACDF group (p = 0.015). The expansion of vertebral canal diameter was significantly correlated with the difference in curvature between the middle and posterior columns (r = 0.523, P < 0.01), and the curvature of the anterior column was correlated with that of the middle and posterior columns (P < 0.05). The curvature change of the anterior column is closely related to the curvature change of the middle column and the posterior column. Compared with ACDF, ACAF expands the diameter and volume of the spinal canal by increasing the curvature of the middle column and reducing the anterior movement of the posterior column.

What is the impact of miniscrew-assisted rapid palatal expansion on the midfacial soft tissues? A prospective three-dimensional stereophotogrammetry study

ObjectivesTo evaluate the midfacial soft tissue changes of the face in patients treated with miniscrew-assisted rapid palatal expansion (MARPE).Materials and methods3D facial images and intra-oral scans (IOS) were obtained before expansion (T0), immediately after completion of expansion (T1), and 1 year after expansion (T2). The 3D images were superimposed and two 3D distance maps were generated to measure the midfacial soft tissue changes: immediate effects between timepoints T0 and T1 and overall effects between T0 and T2. Changes of the alar width were also measured and dental expansion was measured as the interpremolar width (IPW) on IOS.ResultsTwenty-nine patients (22 women, 7 men, mean age 25.9 years) were enrolled. The soft tissue in the regions of the nose, left of philtrum, right of philtrum, and upper lip tubercle demonstrated a statistically significant anterior movement of 0.30 mm, 0.93 mm, 0.74 mm, and 0.81 mm, respectively (p < 0.01) immediately after expansion (T0–T1). These changes persisted as an overall effect (T0–T2). The alar width initially increased by 1.59 mm, and then decreased by 0.08 mm after 1 year, but this effect was not significant. The IPW increased by 4.58 mm and remained stable 1 year later. There was no significant correlation between the increase in IPW and alar width (r = 0.35, p = 0.06).ConclusionsOur findings indicate that MARPE results in significant but small changes of the soft tissue in the peri-oral and nasal regions. However, the clinical importance of these findings is limited.Clinical relevanceMARPE is an effective treatment modality to expand the maxilla, incurring only minimal and clinically insignificant changes to the midfacial soft tissues.

Kinematics of the jaw following total temporomandibular joint replacement surgery

Total temporomandibular joint (TMJ) replacement surgery aims to improve mandibular function, reduce pain and enhance quality of life in patients suffering from end-stage TMJ disorders. Traditional post-operative jaw evaluation is carried out using measurement of maximum interincisal opening distance; however, this can correlate poorly to joint function. The present study aimed to evaluate three-dimensional (3D) jaw motion during border movements and chewing in unilateral total TMJ replacement patients and healthy controls. Motion analysis experiments were performed on six unilateral total TMJ replacement patients and ten age-matched healthy controls. Subject-specific motion tracking plates worn by each participant were registered to CT scans of each participant’s skull and mandible to enable anatomical mandibular kinematics measurement using an optoelectronic system. Participants performed 15 repetitions of maximal opening, protrusion, lateral excursions, and chewing cycles. Total TMJ replacement patients had significantly smaller incisal displacements at maximum mouth opening relative to the controls (median difference: 7.1 mm, p = 0.002) and decreased anterior translation of the prosthetic condyle (median difference: 10.5 mm, p = 0.002). When TMJ replacement subjects chewed using their contralateral molars, there was a significant increase in inferior condylar translation of the non-working condyle (median difference: 9.7 mm, p = 0.016). This study found that unilateral total TMJ replacement surgery was associated with mouth opening capacity within the range of healthy individuals, but reduced anterior movement of the prosthetic condyle and restricted protrusion and lateral excursions. The results provide future direction for prosthetic TMJ design to enhance postsurgical implant functionality and improve long-term clinical outcomes for prosthesis recipients.

Using digital image correlation to measure displacement and strain during involving distal movement of anterior teeth with clear aligner.

To investigate methods to suppress the bowing effects of lingual inclination and anterior tooth extrusion, digital image correlation (DIC) was used to evaluate aligner displacement in three-dimensions through comparing the distal movement of six and four anterior teeth. Computed tomography scans were used to measure aligner thickness and shape. Based on displacement direction and magnitude, a desirable deformation mode with minimal lingual inclination and extrusion was observed during distal movement of four anterior teeth. The aligner had a rigid "constriction zone" between the lateral incisor and the canine, facilitating control localized to the anterior teeth and minimizing the reaction of the molars. The mechanical behavior of aligners was greatly affected by the method of anterior teeth movement and the shape of aligners. DIC-based displacement measurements are useful in investigating correction directionality.

Changes in condylar position during orthodontic treatment depending on the amount of incisor retraction: a cone-beam computed tomography study.

Orthodontic treatment may be associated with temporomandibular disorders through changes in the condylar position. This study aimed to evaluate changes in the condylar position among different amounts of maxillary incisor retraction during orthodontic treatment using cone-beam computed tomography images. Fifty-four participants were enrolled and divided into minimal (n = 14), moderate (n = 20), and maximal (n = 20) retraction groups based on the amount of incisor retraction (< 1, 1-6, and > 6mm, respectively). Changes in condylar position before (T0) and after (T1) orthodontic treatment were assessed for the superior, anterior, posterior, and medial joint spaces (SJS, AJS, PJS, and MJS, respectively). Changes in joint spaces were compared between T0 and T1 in each group using paired t-tests and among the three groups using analysis of variance. Anterior movement of the condyle was observed in the maximal retraction group with a 0.2mm decrease in ΔAJS and a 0.2mm increase in ΔPJS, significantly greater than those in the minimal retraction group. The AJS and PJS showed statistically significant differences between T0 and T1 (P < 0.05) in the maximal retraction group. The condyle may show a statistically significant but clinically insignificant forward movement in the maximal incisor retraction group, whereas it was relatively stable in the minimal and moderate incisor retraction groups. More attention should be paid to the signs and symptoms of the condyle in patients with excessive incisor retraction during orthodontic treatment.

Features of Diagnostics and Course of Hypertrophic Cardiomyopathy in Real Clinical Practice

Introduction and purpose. Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular (LV) wall thickening not associated with increased afterload (hypertension and aortic stenosis), is usually caused by mutations in sarcomeric protein genes, and is inherited in an autosomal dominant manner. Unlike HCM, myocardial hypertrophy in its phenocopies is associated with the accumulation of substances such as amyloid, glycogen, etc. in the myocardium. The aim of our work was to analyze the features of the diagnosis and course of HCM in real clinical practice. Material and methods. A retrospective analysis of medical records of 80 patients (56.3 % of men) discharged with a diagnosis of HCM from a multidisciplinary hospital in Moscow in the period from 2007 to 2021 was carried out. The diagnosis of HCM in all patients was established on the basis of echocardiography data. The median age (25th and 75th percentiles are indicated in brackets) was 57 (48.5; 63) years. The duration of hospitalization was 8 (6; 12.5) days. Results. The reason for hospitalization was angina syndrome in 35 %, suspicion of acute coronary syndrome in 16.3 %, paroxysmal atrial fibrillation (AF) in 11.3 %, decompensation of chronic heart failure in 11.3 %, syncope in 7.5 % %, hypertensive crisis in 3.8 %, coronary angiography in 3.8 %, pacemaker implantation in 2.5 %, consultation with an arrhythmologist in 2.5 %, implantation of a cardioverter-defibrillator in 1.2 %, medical examination to resolve the issue of fitness for military service in 1.2 %, acute cerebrovascular accident in 1.2 %, hypotension in 1.2 %, drug bradycardia in 1.2 % of patients. Before hospitalization, a history of myocardial infarction was diagnosed in 15 %, arterial hypertension — in 53.8 %, chronic heart failure — in 77.6 %, chronic kidney disease — in 21.3 % of patients. Prior to the analyzed hospitalization, a history of myocardial infarction was diagnosed in 15 %, arterial hypertension in 53.8 %, chronic heart failure in 77.6 %, chronic kidney disease in 21.3 % of patients. LV wall thickness ≥1.5 cm was detected in 91.2 %, symmetrical form of hypertrophy — 22.1 %, apical — 5.2 %, papillary muscle hypertrophy — 1.3 %, interventricular septum — 71.4 % of patients. Permanent obstruction of the LV outflow tract (LVOTO) was detected in 62.8 % (9.0 % of patients had a history of septal reduction), transient LVOTO — in 1.3 %, non-obstructive HCM — in 35.9 %. The ejection fraction (EF) of the LV (according to Simpson) was 63 (55-70) %, CHF with reduced LV EF &lt;40 % was detected in 3.8 %, with a moderately reduced LV EF (40-49 %) — in 5 %, with preserved LV EF — in 68.8 % of patients. Anterior systolic movement of the anterior leaflet of the mitral valve occurred in 47.5 %, prolapse of the anterior leaflet of the mitral valve was described in 7.14 %. Mitral regurgitation was registered in 75 % of patients. 45 % of patients with HCM suffered from AF: permanent 15 %, paroxysmal 23.8 %, persistent 6.2 % of patients. During hospitalization, ventricular tachycardia was registered in 7.5 %, supraventricular tachycardia — 3.8 %, conduction disturbances were noted in 36.3 % of patients, of which atrioventricular block in 6.3 %, blockade of the right bundle branch block in 21.3 %, left bundle branch block in 15 %, and Wolff-Parkinson-White syndrome in 1.3 % . Implantation of a pacemaker in history was in 5 %, including in connection with MorgagniAdams-Stokes attacks — in 3.8 % of patients. During a median follow-up of 87 (interquartile range 45–131.5) months, 13.8 % of patients with HCM died. In deceased patients, LVOTO was significantly more common (in the dead 100 %, in the living 58.2 %, p = 0.006) and AF (in the dead 72.7 %, in the living 40.6 %, p = 0.047). Genetic testing and exclusion of HCM phenocopies was not performed during hospitalization and was not recommended for any patient. Conclusion. In real clinical practice, in most cases, only phenotypic diagnosis of HCM is carried out according to echocardiography, and screening for genetic mutations and HCM phenocopies is not performed. It is necessary to widely introduce genetic testing and screening for HCM phenocopies for the timely diagnosis of pathology that requires the appointment of specific pathogenetic therapy to improve the prognosis of patients

Quantification of pharyngeal airway space changes after two-jaw orthognathic surgery in skeletal class III patients

BackgroundSkeletal class III malocclusion is a common dentofacial deformity. Orthognathic treatment changes the position of the jaws and affects the shape of the upper airway to some extent. The aim of this study was to use multislice spiral computer tomography data and orthognathic knowledge to quantify the relationship between the amount of surgical movement of the maxilla or mandible in all three spatial planes and the changes in airway volume that occurred.MethodsA retrospective study of 50 patients was conducted. Preoperative and postoperative linear changes related to skeletal movements of the maxilla and mandible were measured and compared to changes in the most constricted axial level (MCA) and its anteroposterior (MCA-AP) and transverse diameters (MCA-TV). Correlation tests and linear regression analysis were performed.ResultsSignificant interactions were observed between the anterior vertical movement of the maxilla and the MCA-AP. The anteroposterior movement distance of the mandible was significantly correlated with changes in the oropharyngeal, velopharyngeal, total airway volume, MCA, MCA-AP, and MCA-TV. The change in the mandibular plane angle was significantly correlated with the change in velopharyngeal volume, total airway volume (nasopharynx, oropharynx, velopharynx), and MCA.The linear regression model showed that oropharyngeal volume decreased by 350.04 mm3, velopharyngeal volume decreased by 311.50 mm3, total airway volume decreased by 790.46 mm3, MCA decreased by 10.96 mm2 and MCA-AP decreased by 0.73 mm2 when point B was setback by 1 mm.ConclusionsAnteroposterior mandibular control is the key to successful airway management in all patients. This study provides estimates of volume change per millimeter of setback to guide surgeons in treatment planning.

테니스 포핸드 스트로크 시 그립 형태에 따른 하지관절 움직임 및 상지근의 변화 차이 분석

The study was to examined the lower extremity movements of the semi-western and western grips during the forehand stroke in five male tennis players and determined the muscle activity of the upper extremities, with the following conclusions. First, the overall duration of each segment did not show significant differences, but the semi-western grip showed faster duration on average at P1 and the western grip at P2. Second, it was found that it is desirable to reduce the change in left-right width at the moment of impact to increase the rotational force and facilitate the weight transfer with anterior movement. Third, the lower extremity joint angles showed a statistically significant difference in the left hip joint E1 (p&lt;.05), and a significant difference in the right ancle joint. Fourth, the mobilization of the spinae muscles to generate trunk rotation for smooth transfer of lower extremity kinetic energy and the activity of the deltoid and hip flexor muscles for a strong swing were found to be important factors in transferring momentum to the ball.