Aim and objectiveTo assess the effect of various arch parameters, bigonial angle, and caries occurrence on mandibular incisors crowding during the early mixed dentition period.Materials and methodsSixty children (mean age of 7.5 years) with mandibular anterior incisors crowding and class I molar relationship in early mixed dentition were selected. Bigonial width (BW) and caries occurrence were recorded during patient examination. The study casts were prepared divided into a normal group (NG) and crowded group (CG). Different vertical and transverse arch perimeters along with space available for the permanent mandibular incisors were measured manually. Statistical analysis was done to establish the association of all these variables with two crowding groups.ResultsThe total incisor width or the tooth material was significantly more, and all arch parameters were less in measurements in CG than NG. The available space, BW, and caries occurrence did not differ significantly between NG and CG.ConclusionThe amount of tooth material and individual variations in arch parameters significantly contribute to mandibular anterior crowding in the early mixed dentition period irrespective of the age and gender of the child.Clinical significanceAll cases of early mixed dentition mandibular incisors crowding should be individually assessed for arch length discrepancy, and transverse discrepancy results of this study help in the prediction of crowding before an establishment of a customized treatment plan with the use of lingual arch or lip bumper appliances in patients with anterior mandibular crowding may be valuable.How to cite this articlePaul S, Garg S, Saraf BG, et al. Arch Measurements, Bigonial Width, Dental Caries, and Their Effect on Occurrence of Mandibular Incisors Crowding in Early Mixed Dentition Period. Int J Clin Pediatr Dent 2021;14(S-1):S57–S62.