Varicocele is a major cause of male infertility. Different studies have shown that varicocele is associated with a progredient deterioration of testicular function. This fact constitutes the indication for treatment of varicocele, which has been underscored by the results of studies demonstrating that the correction of varicocele can arrest testicular damage and can lead to improved spermiogenesis (Hadziselimovic et al., 1989; Kass & Belman et al., 1987). We have established antegrade scrotal sclerotherapy (ASS) for treatment of varicocele (Tauber & Johnsen, 1994). This study wants to examine the influence of antegrade sclerotherapy of varicocele on spermiogenesis and generative power.