Data on fecal evacuation disorder (FED) causing chronic constipation (CC) is scanty in India. Prospectively maintained data of 249 consecutive patients with CC (Rome III) referred for investigations were retrospectively analyzed. Of 249 patients (43.7 ± 16.2years, 174 males), 135/242 (55.8%), 57/249 (22.9%), and 83/136 (61.0%) had abnormal balloon expulsion test (>200g), anorectal manometry [>100mmHg resting pressure (n = 4), >167mmHg squeeze pressure (n = 46), and both (n = 7)], and defecography (anorectal angle not opening by >15° during defecation, perineal descent ≥4cm, and/or rectocele), respectively. Though 181/249 (72.6%) had one test abnormality, 86/249 (34%) had FED (greater than or equal to two abnormalities), 44/65 (67.6%) of whom had a defecation index ≤1.4. Rome III criteria for irritable bowel syndrome were equally fulfilled by patients with and without FED [74/83 (89%) vs. 117/144 (81.2%); p = ns]. On univariate analysis, straining duration, prolonged straining [≥30min; 21/39 (53.8%) vs. 15/65 (23.1%); p = 0.002], incomplete evacuation [75/77 (97.4%) vs. 95/114 (83.3%); p = 0.004], and >3 stools/week [60/75 (80%) vs. 76/128 (60%); p = 0.004] were commoner among the FED patients though age, gender, symptom duration, mucus, manual evacuation, and stool forms were comparable. Resting and squeeze pressures and balloon volume at maximum tolerable limit were higher, and the sphincter tended to be shorter in FED. Prolonged straining, incomplete evacuation, and squeeze pressure were significant on multivariate analysis. Manometry and defecography abnormalities were commoner among the female FED patients. FED is not uncommon, which fulfills the Rome III criteria for IBS, and prolonged straining may be suggestive; abnormal defecography and manometry are commoner in female.
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