Knowledge of the standard anatomy and anomalies of the hepatic vessels is mandatory to obviate complications secondary to hepatic surgery, especially in liver transplantation, as well as in many radiological procedures such as transarterial chemoembolization for hepatic tumors. An international classification of the main variations in the vascular anatomy of the liver was proposed by Michels [1] in 1966 and modified by Hiatt et al. [2] in 1994. A standard finding, in 52–79% of cases, is the common hepatic artery arising from the celiac trunk, becoming the proper hepatic artery, and thus giving off the left and right hepatic arteries. Many other articles, in particular those concerned with living related liver transplant donor candidates, have tried to describe any unreported variations in direct relation to the potential surgical risk [3, 4]. Another large series was recently published by Song and colleagues [5], who did an angiographic analysis of nonhepatic arteries originating from the hepatic arteries in 250 patients. They found the right gastric artery to be the most common of these nonhepatic arteries, followed by the hepatic falciform artery, accessory left gastric artery, posterior superior pancreaticoduodenal artery, and left inferior phrenic artery; furthermore the left hepatic artery was the most frequent origin of nonhepatic arteries. We present a case of an accessory epiploic artery originating from a segmental branch of the right hepatic artery, also supplying a hepatocellular carcinoma located at the hepatic dome. The anomaly was discovered on the MDCT scan (Fig. 1) in association with a Michels type V variation (accessory right hepatic artery arising from the superior mesenteric artery) [1] (Fig. 2). The MDCT finding was subsequently confirmed at selective segmental arteriography of the VIII segment (Fig. 3) done before chemoembolization. The treatment was subsequently safely performed by positioning a microcatheter distal to the origin of this accessory epiploic artery. To our knowledge this anatomic variation of the hepatic vasculature has not been described previously.