The aim of the study was to monitor the adaptive changes dynamics of locomotor control during hindlimb suspension (HS). We performed the kinematic analysis of the rat locomotor movements before, during and after 7-days HS according to the Morey-Holton. We observed the ankle and knee hyperextension in the rats’ treadmill locomotion after the 7-days HS. Despite the lack of weight-bearing position of the hindquarter, the air-stepping was present during HS. It was found the adaptive changes of the kinematic characteristic of locomotor movements during HS, namely progressive increase of ankle and knee extension, however contrary to hip flexion. These corresponded to the constrained position of hind limbs during passive suspension with the ankle, knee hyperextension, and hip hyperflexion. The data obtained indicate that the specific gait adjustments, related to the pattern formation neuronal network of the central pattern generator, is possibly caused by the progressive reorganization of the proprioceptive feedback in condition of constrained body posture and hindlimb joints configuration during HS.