Anise Research Articles

Anise and Fennel Essential Oils and Their Combination as Natural and Safe Housefly Repellents.

Essential oils (EOs) are effective repellents and eco-friendly alternatives. We tested single and combination EOs of fennel and anise for repellency and stability against houseflies. All treatments were stored at 27 °C for up to 360 days. Efficacies were compared against α-cypermethrin as a reference. Safety bioassay used on two representative non-target species (guppies and earthworms) confirmed safety. The strongest repellency and stability, 100% repellency and RC50 of 0.4 mL/m3 on day 1, was achieved by a fennel + anise EO combination (1:1). After 360 days, these combinations remained effective (95% repellency), and RC50 = 0.8 mL/m3. The EO combinations were more effective than all single EOs and α-cypermethrin at all times, showing strong synergy with a synergistic repellent index of 2.4 to 3.3. This fennel + anise EO combination was more than 24 times more effective as a repellent than α-cypermethrin. Morphological damage included damaged antennae with twisted flagella and abnormal aristae. All single and combination EOs were not toxic to the non-targets and could be considered safe, whereas α-cypermethrin was highly toxic to them. Thus, the fennel + anise EO combination has great potential to be developed as a safe, natural repellent for managing housefly populations.

Insecticidal compositions of natural pyrethrins and substituted benzodioxolanes from vegetable oils

In order to confirm the theoretical calculations of the validity of the use of natural pyrethrins together with the components of vegetable oils, biologically active compositions of insecticides isolated from Dalmatian chamomile (Pyrethrum cinerariaefolium) and synergistic substances obtained from sesame, kanang and anise oils have been developed. It was found that insecticidal compositions showed their effectiveness against model insect pests (greenhouse whitefly – Trialeurodes vaporariorum). It is shown that the developed compositions can be used as a promising basis for the creation of new means of protecting agricultural plants from insect pests.

Herbal Extracts Mixed with Essential Oils: A Network Approach for Gastric and Intestinal Motility Disorders.

Three herbal extracts (Asparagus racemosus Willd., Tabebuia avellanedae Lorentz, and Glycyrrhiza glabra L.) were mixed with three essential oils (Foeniculum vulgare Mill., Mentha piperita L., and Pimpinella anisum L.) to formulate a product (HEMEO) whose active compounds include saponins and steroids in Asparagus racemosus, known for their anti-inflammatory properties; glycyrrhizin and flavonoids in Glycyrrhiza glabra, which exhibit gastroprotective and antispasmodic effects; menthol in Mentha piperita, contributing with antispasmodic and antimicrobial properties; and anethole and polyphenols in Pimpinella anisum, which modulate intestinal motility and offer antimicrobial activity. HEMEO was formulated for applications in intestinal motility disorders. HEMEO was evaluated for spontaneous and induced motility effects in isolated guinea pig ileum, colon, and stomach. Ex vivo experiments were conducted using LabChart software v7.0, and the product's antibacterial action against Helicobacter pylori and its antioxidant effects were assessed through disc diffusion and FRAP assays. The presence of the volatile compounds in the formulation was confirmed by GC-MS analysis; the TPC of HEMEO, determined using the Folin-Ciocalteu method, was 9.925 ± 0.42 mg GAE/g. HEMEO showed a phenolic content correlated with its antioxidant potential and in addition inhibited H. pylori growth and demonstrated notable antioxidant properties, suggesting its role as a supportive agent in digestive processes and in managing motility disorders.

Active Components of 16 Essential Oils and Their Fumigation Effects on Galleria mellonella (Lepidoptera: Pyralidae).

The greater wax moth (GWM, Galleria mellonella) is a prevalent pest of the honeybee and a significant risk to both honeybee populations and honeycomb storage. Research on the toxicity of essential oils (EOs) to GWM larvae has provided promising results, although their ovicidal effects and active ingredients require further study. Identifying effective plant compounds is essential for developing insecticides for GWM control. This study assessed the fumigation efficacy of 16 EOs on GWM eggs and fifth instar larvae and determined the effectiveness of these EOs and their primary components for fumigating fifth larvae. Wintergreen, star anise, and clove oils demonstrated significant insecticidal effects on GWM eggs and fifth instar larvae, resulting in a mortality rate exceeding 80% within 48 h. Gas chromatography-mass spectrometry analysis identified methyl salicylate (93.26%), trans-anethole (87.75%), and eugenol (77.75%) as the primary compounds in wintergreen, star anise, and clove oils, respectively. Further toxicity testing confirmed that these compounds were responsible for the observed insecticidal properties of the EOs. Notably, trans-anethole exhibited the lowest LC50 value (25.22 μL/L) against the fifth instar larvae of GWM and significant toxicity against GWM eggs and fifth instar larvae, suggesting its potential as a viable option for the future control of GWM populations.

Efficacy of Melissa officinalis, Pimpinella anisum, and Rosa damascena formula in irritable bowel syndrome: A double-blind, randomized trial

Efficacy of Melissa officinalis, Pimpinella anisum, and Rosa damascena formula in irritable bowel syndrome: A double-blind, randomized trial

Impact of Curcumin and Ground Anise Seeds dietary Supplementation on The egg quality traits of Laying Hens ..

Impact of Curcumin and Ground Anise Seeds dietary Supplementation on The egg quality traits of Laying Hens ..

Effects of the Herbal Soft Gel Capsule Containing Pimpinella Anisum, Oenothera Biennis, and Salvia Sclarea Oils on Premenstrual Syndrome: A Triple-blinded Randomized Controlled Trial Study

Objective: Premenstrual syndrome (PMS) is a combination of physical and psychological symptoms that start during the luteal phase. There are no specific effective and safe remedies to relieve these symptoms. However, there is a great tendency to use herbal medicines instead of chemical medicines. This study aimed to assess and compare the effects of a soft gel capsule containing Pimpinella anisum, Oenothera biennis, and Salvia sclarea oils (POS) with control, before and after use in two consecutive cycles, on physical and psychological symptoms of PMS. Methods: This was a triple-blind randomized clinical trial performed on 67 female students, who were residents in dormitories of the Shahid Beheshti University of Medical Science in Tehran, Iran. The participants were randomly divided into two groups: soft gel capsule users containing POS as the intervention group (n=32) and sunflower as the control group (SF) (n=35). The participants were 18-35 years old female students who were affected by PMS. The capsules were used twice daily, from the 21st day of the menstrual cycle to 2 days after the menstruation, for two consecutive menstrual cycles. The tools for data collection were three questionnaires: a personal information questionnaire, a valid and reliable daily PMS symptom report (DSR) form, and a side effects assessment questionnaire. The physical, psychological, and general symptoms of PMS were assessed by the DSR, and the results were taken before and after intervention and between groups of the study. Results: Before and after the intervention, the comparison showed significant effectiveness of POC in reducing general, physical, and psychological symptoms after the first and second months of use. However, the comparison of the groups did not show a significant difference between the two groups regarding their PMS symptoms and the side effects of the medicines (p<0.05). Conclusion: POS is a combination of three herbal medicines effective on the symptoms of premenstrual syndrome, which can be used effectively and safely to improve the physical and psychological symptoms of premenstrual syndrome. This herbal remedy can be recommended by health care providers to women, who suffer from PMS symptoms and prefer to use herbal remedies instead of synthetic drugs. Further studies are necessary to evaluate the combined herbal remedies as well as the effectiveness of sunflower oil on PMS symptoms. Clinical Trail Registration No.: IRCT20190306042943N1.

The use of complementary and alternative medicine among surgical patients: a cross-sectional study

BackgroundThe use of complementary and alternative medicine (CAM) has increased substantially around the world; various global studies have documented the use of CAM by surgical patients in the preoperative period, with rates of herbal medications and other nonherbal treatments ranging from 12 to 69%. This study aimed to identify the prevalence of CAM and its patterns of use among surgical patients.MethodsFrom December 2020 to April 2021, a descriptive cross-sectional study was undertaken in Palestine. A face‒to-face interview questionnaire was used. The participants were asked questions regarding sociodemographics, clinical information, CAM usage, reasons for its use, and opinions on its efficacy.ResultsAmong the 300 surgical patients who were interviewed in this study, 252 (84.0%) reported that they had ever used CAM, while a total of 122 (48.4%) had used CAM before their surgery, 81.7% of the respondents used herbal methods, and 64.7% of them used nonherbal methods. CAM use among our study population was not linked to specific demographics or other characteristics, except health insurance (p = 0.004). The most commonly used herbs among surgical patients are Salvia officinalis L. (Sage) (84.1%) and Pimpinella anisum L. (Anise) (75.5%). The highest percentage was found among patients with university qualifications (73.2%), who used more than three methods (p < 0.001). In addition, 59.4% of the females used more than three therapies, whereas 45.9% of the males did (p = 0.032).ConclusionsThe herbal methods used are common among surgical patients in Palestine and are consistent with the enormous increase in the use of CAM. Therefore, awareness should be raised among the public regarding the risks and benefits of CAM use.

Green recovery of nuciferine from lotus leaf via star anise oil based two-phase solvent extraction integrated with back-extraction

In this study, we present a novel green bio-based solvent, star anise oil (SAO), which was employed to develop a two-phase solvent system incorporating both alkaline and acidic solutions for the simultaneous extraction and purification of nuciferine from waste lotus leaf. This integrative approach effectively combines two-phase solvent extraction (TPSE) with back-extraction (BE), resulting in a more streamlined extraction process that requires only vortexing (or stirring) and centrifugation, thus simplifying the overall procedure. It is important to note that this method uses very little solvent (only 2.5 times the volume of SAO relative to the weight of the lotus leaf) and takes just 4 min per extraction. After three such extractions, the recovery rate of nuciferine can reach as high as 96.9%. Unlike volatile solvents such as petroleum ether and ethyl acetate, SAO's high boiling point negates the necessity for nitrogen protection during centrifugation, thereby addressing the Pickering emulsification issues caused by particles. Only two back-extraction operations are needed to recover 96.9% of nunciferine from the TPSE extract, resulting in a nunciferine content of 45.4%. Furthermore, approximately 90% of the SAO can be directly reused for at least five cycles without additional purification. Additionally, 85.0% of the SAO remaining in the TPSE waste can be recovered through hydrodistillation (HD) within 30 min. The excellent performance in biomass and extraction solvent selection, solvent repurposing, and other factors contributed to a Path2Green score of 0.28 for this method, highlighting its suitability for the green recovery of nuciferine from lotus leaf.

Exploring the Effects of a Calming Herbal Tea Blend on Perioperative Anxiety: A Randomized Clinical Trial.

This research aimed to explore the effectiveness of consuming a calming herbal tea blend, comprising Matricaria recutita, Passiflora incarnata L., and Pimpinella anisum L., in comparison to a placebo tea infused with lemon, to ascertain whether the herbal blend possesses anxiety-reducing properties capable of alleviating perioperative anxiety. The study adopted a clinical randomized, double-blind design and collected data from volunteers undergoing elective surgery at Hospital Unimed Erechim in the northern region of Rio Grande do Sul, Brazil. A total of 210 participants were enrolled and randomly allocated into two groups: one receiving the placebo tea and the other the sedative herbal tea. All participants completed a questionnaire postoperatively to assess anxiety levels, employing the adapted Portuguese version of the DASS-21 Scale (Depression, Anxiety, and Stress Scale). Results revealed no significant difference in anxiety levels between the group consuming the calming herbal tea and the group consuming the placebo tea. However, consumption of the anxiolytic herbal tea was associated with a notable increase in positive sentiments toward the surgical procedure (P = .0009). Furthermore, the study demonstrated that the DASS-21 questionnaire exhibited a preoperative profile comparable to the clinical scenarios depicted by the scale. Both the calming herbal tea and the placebo tea were found to effectively mitigate perioperative anxiety. This suggests that both options-soothing herbal tea and placebo tea-can be considered safe, efficacious, and pleasant methods for reducing preoperative fasting requirements.

Antimicrobial Activity of Some Medicinal Plants from the Apiaceae Family

In this study, the antimicrobial activity of some medicinal plant seeds from the Apiaceae family which are anise, cumin, and fennel was investigated. Moreover, ethanol (80%) and methanol (80%) extracts of anise, cumin, and fennel seeds and essential oils of them were performed for this aim. Escherichia coli ATCC 25922 and Salmonella Enteritidis ATCC 13076, Bacillus subtilis ATCC 6633, Streptecoccus mutans ATCC 25175 and Listeria monocytogenes ATCC7644 were utilized as test microorganisms. Then, essential oils and ethanol extracts of cumin seeds showed the highest antimicrobial effects on almost all of the test microorganisms. While methanol extracts of fennel seeds had the highest antimicrobial effects against St. mutans and B. subtilis when compared to other methanol extracts. Additionally, methanol extracts of anise seeds indicated the highest effect on E. coli. However, all types of medicinal plant seeds had antimicrobial effects on test microorganisms in various severities (7.00-20.00 mm zone diameter) except L. monocytogenes. Thus, the results support existing scientific evidence for the evaluation of these plants as natural antimicrobial agents in several industries including food and drugs.

Investigating Pregnant Women's Attitudes toward Herbal Remedies: A Cross-Sectional Study.

Herbal remedies play a significant role in daily life, regardless of region or ethnicity. While they offer various health benefits, they may also pose risks, including toxicity and undesirable side effects. Pregnant women, one of the most vulnerable populations, frequently use herbal remedies, often without informing their healthcare providers, which can lead to unforeseen consequences for both the mother and the fetus. A total of 590 women participated in an online survey designed to assess demographic factors, awareness of herbal remedies during pregnancy, and the potential impact of these remedies on maternal and fetal health. The survey revealed that 35.8% of the participants used herbal remedies during pregnancy. The most common reasons for their use were beliefs in their safety and family recommendations. Anise (Pimpinella anisum L.) was the most frequently used herb. The findings indicate that pregnant women generally have limited knowledge about herbal remedies and their potential risks. To mitigate this, it is essential to develop and disseminate comprehensive safety and efficacy guidelines. Both physicians and pregnant women should be well-informed to ensure the protection of maternal and fetal health.

Anise essential oil immobilized in chitosan microparticles: a novel bactericidal material for food protection.

Foodborne infections in humans are one of the major concerns of the food industries, especially for minimally processed foods (MPF). Thereby, the packaging industry applies free chlorine in the sanitization process, ensuring the elimination of any fecal coliforms or pathogenic microorganisms. However, free chlorine's propensity to react with organic matter, forming toxic compounds such as trihalomethanes and haloacetic acid. Therefore, the present work aimed to synthesize a novel organic biomaterial as an alternative to free chlorine. Chitosan microparticles were produced, with Pimpinella anisum (anise) essential oil immobilized in the biopolymer matrix (MPsQTO). The characterization of this biomaterial was done through GC-MS/MS, FT-IR, and SEM. Antimicrobial assays proved that the MPsQTO presented antibacterial activity for Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, and Bacillus subtilis at 300 µL mL-1 of concentration. The fluorescence microscope also showed the MPsQTO targets the cytoplasmatic membrane, which is responsible for cell death in the first minutes of contact. Studies with the mutant B. subtilis (amy::pspac-ftsZ-gfpmut1) and the Saccharomyces cerevisiae D7 also proved that the biomaterial did not affect the genetic material and did not have any mutagenic/carcinogenic effect on the cells. The sanitization assays with pumpkin MPF proved that the MPsQTO is more effective than free chlorine, increasing the shelf-life of the MPF. Consequently, the novel biomaterial proposed in this work is a promising alternative to traditional chemical sanitizers.

Potential Use and Chemical Analysis of Some Natural Plant Extracts for Controlling Listeria spp. Growth In Vitro and in Food.

Listeria are Gram-negative intracellular foodborne pathogens that can cause invasive infections with high mortality rates. In this work, the antibacterial activity of ten essential oils, infusion extracts, and decoction extracts of some medicinal plants was tested against Listeria monocytogenes and listeria ivanovii strains. The effects of different physical conditions including temperature, pH, sodium chloride, and some organic acids were studied. The results showed that the water extracts gave the maximum bacterial inhibition, while ethanolic extract was inactive against the tested Listeria spp. The antibiotic sensitivity of L. monocytogenes LMG10470 and L. ivanovii LMZ11352 was tested against five antibiotics including imipenem, levofloxacin, amikacin, ampicillin, and amoxicillin. Imipenem was the most effective antibiotic, resulting in inhibition zones of 40 mm and 31 mm for L. monocytogenes and L. ivanovii, respectively. When imipenem mixed with Syzygium aromaticum oil, Salvia officinalis oil, Pimpinella anisum infusion, and Mentha piperita infusion each, the water extract of Moringa oleifera leaves and seeds against LMG10470 and LMZ11352 resulted in broader antibacterial activity. The antimicrobial activity of both Pimpinella anisum and Mentha piperita plant extracts is related to a variety of bioactive compounds indicated by gas chromatography-mass spectrometry analysis of these two plant extracts. These two plant extracts seemed to contain many chemical compounds elucidated by gas chromatography-mass spectrometry (GC-MS) and infrared radiation spectra. These compounds could be classified into different chemical groups such as ethers, heterocyclic compounds, aromatic aldehydes, condensed heterocyclic compounds, ketones, alicyclic compounds, aromatics, esters, herbicides, saturated fatty acids, and unsaturated fatty acids. The use of these natural compounds seems to be a useful technological adjuvant for the control of Listeria spp. in foods.

Eco-friendly corrosion inhibition and scale control in seawater using Foeniculum vulgare and Pimpinella anisum extracts with chemical compounds

This study investigated the corrosion inhibition and scale control properties of both natural extracts and chemical inhibitors for C25 galvanized steel sheets with an 85-μm thick zinc coating steel exposed to seawater. The inhibitors, including Foeniculum vulgare (AF-Sha), Pimpinella anisum (AF-Sim), M640, and Veo, underwent rigorous evaluation through techniques such as Tafel extrapolation, potentiodynamic polarization analysis, concentration factor scale, seawater analysis, X-ray diffraction (XRD), infrared spectroscopy (IR), and conductivity-temperature analysis. Notably, AF-Sha and AF-Sim exhibited outstanding corrosion prevention capabilities, achieving inhibitory efficiencies of 87% and 85%, respectively. Comparative analyses with chemical inhibitors, M640 and Veo, demonstrated promising performance, positioning natural inhibitors as environmentally friendly alternatives. Corrosion rates, inhibition efficiency, and concentration factor scale results provided insights into the inhibitory effectiveness of each compound, with Veo showing superior performance. The study also explored the antiscalant behavior of inhibitors, revealing their ability to prevent corrosion and scale formation. XRD analysis indicated the impact of inhibitors on the crystal structure of scales, while IR spectra provided insights into vibration properties. Conductivity and temperature analyses illustrated the inhibitors' role in reducing ion exchange and gypsum concentration in seawater. These findings suggest that the inhibitors offered robust protection for ferrous metal surfaces and hold significant potential for practical applications. Additionally, our weight loss investigation extends this understanding, demonstrating the practical applicability of corrosion inhibitors like AF-Sha and AF-Sim in real-world scenarios. The presented results contribute significantly to the understanding of galvanized steel corrosion behavior in seawater, offering valuable insights for corrosion engineering applications.

Characterisation and biological activities of synthesised copper oxide nanoparticles from the Pimpinella anisum L. aqueous extract

AbstractNanoparticles can be synthesised by several methods. Due to the long duration, high cost, and toxic by-products of chemical and physical methods, the biological method has become more preferred. Among various sources such as bacteria, fungi, or yeast, the use of plants in biological synthesis has proven to be the most ideal. Many metals can be used in the biological method, including copper oxide (CuO). In this study, copper oxide nanoparticles (CuONPs) were synthesised using Pimpinella anisum L. aqueous extract. For characterisation of the CuONPs, UV–Visible Spectroscopy (UV–Vis), Scanning Electron Microscopy (SEM), Energy Dispersion Spectroscopy (EDS), and Fourier Transform Infrared Spectroscopy (FT-IR) analyses were performed. The biological activity of the P. anisum extract and CuONPs was determined using DNA cleavage (agarose gel electrophoresis), antioxidant (1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and hydrogen peroxide scavenging activity), mutagenic (Ames/Salmonella test), and catalytic (methylene blue degradation) activities. In DNA cleavage activity test, CuONPs completely denatured DNA at high concentrations (100 and 200 μg mL−1) due to their oxidative activity. The results showed that both the extract and CuONPs have antioxidant properties in DPPH and hydrogen peroxide scavenging activities. According to the mutagenicity, CuONPs did not have a mutagenic effect. In catalytic activity, CuONPs degraded methylene blue within 240 min by 99.45%.

The Antimicrobial and Sensory Characteristics of Dairy- and Non-Dairy-Based Foods Supplemented with Anise Oil

The Antimicrobial and Sensory Characteristics of Dairy- and Non-Dairy-Based Foods Supplemented with Anise Oil

Multicomponent double Povarov reaction for julolidine: Synthesis and mechanistic insights

Julolidines constitute a class of N-heterocyclic molecules that behave as molecular rotors. Due to their fluorescent properties, they are applied in a wide range of technological fields, such as the production of solar cells, fluorescent biomarkers or bioimaging, and photoconductive materials. In the present work, we developed a methodology for the synthesis of julolidines through the one-pot tandem reaction-based application of multicomponent double Povarov reaction (MCPR) using BF3.OEt2 as the catalyst (25 mol%), star anise oil rich in trans-anethole as the substrate, and water as the solvent in reactions at room temperature. The julolidines were obtained with total yields ranging from 55 to 95 %. A mechanistic study allowed for the conclusion that these MCPRs take place through an ionic mechanism and also that released protons by the reaction between BF3.Et2O and water are involved in the catalytic process. After extracting the products from the reaction medium, the remaining aqueous phase containing the catalyst can be reused for up to six catalytic cycles with a minimal loss of catalytic efficiency. DFT calculations were conducted to investigate the catalytic cycle using BF3.Et2O and ZnCl2 as catalysts. The results indicate that the formation of iminium ions is a prerequisite for the progress of the reaction (MCPR). When BF3.Et2O and water are involved, the reaction proceeds via Brønsted catalysis, and the formation of iminium ions occurs in an exothermic and spontaneous process. However, when the ZnCl2 is used, the process is Lewis catalyzed to form the first iminium ion and is endergonic, shifting the equilibrium towards the reactants and inhibiting the cyclization.

Investigating the Endophyte Actinomycetota sp. JW0824 Strain as a Potential Bioinoculant to Enhance the Yield, Nutritive Value, and Chemical Composition of Different Cultivars of Anise (Pimpinella anisum L.) Seeds.

Anise (Pimpinella anisum L.) seeds have various nutritional and therapeutic benefits and are thus considered a valuable addition to animal and human health. Hence, in this study, we aimed to induce the nutritive and biological value of anise seeds. To this end, the potential biofortification effect of the endophytic Actinomycetota sp. JW0824 strain, isolated during the fall of 2023 from the medicinal plant Achyranthes aspera, exhibiting natural distribution in the Jazan region of Saudi Arabia, was investigated in four varieties of anise seeds from Egypt, Tunisia, Syria, and Morocco. Results revealed significant increments (p < 0.05) in the seed dry weight percentage (DW%) and oil yields. In line with increased biomass accumulation, the metabolism of the primary and secondary metabolites was increased. There were differential increases in proteins, sugars, flavonoids, alkaloids, phenols, vitamins (e.g., β-carotene, ascorbic acid), and essential oil components (e.g., phenylpropanoids and monoterpenes), along with their precursor phenylalanine. Consistently, the activity of L-phenylalanine aminolyase (PAL) was increased in the Egyptian and Tunisian varieties at 83.88% and 77.19%, respectively, while 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) activity increased in all varieties, with a significant 179.31% rise in the Egyptian variety. These findings highlight the beneficial effects of Actinomycetota sp. JW0824 as a bioinoculant for anise seeds, suggesting its potential application in agricultural practices to improve seed yield and quality. Further field trials are recommended to assess the commercial viability of this endophyte for enhancing anise seed production and potentially benefiting other plant species.

ANTIMICROBIAL ACTIVITY OF PIMPINELLA - AN OVERVIEW

Pimpinella species, belonging to Apiaceae (Lindl.) family, utilized in many fields of industry as spice, fruit, vegetable and beverage have especially been used in traditional medicine as a remedy in various countries. Essential oils (EO) of various species including Pimpinella cypria, Pimpinella kotshchyana, Pimpinella saxifraga, and Pimpinella anisum were reported to have antibacterial and antifungal activities. Furthermore, it was observed that P. anisum EO possessed antiviral properties. Along with its antimicrobial activity, Pimpinella species were found to have antioxidant, anti-inflammatory, anticonvulsant, antispasmodic, estrogenic, cytotoxic, insecticidal, and repellent properties. This review aims to provide an enhanced understanding on some Pimpinella species’ morphology, chemical constituent, industrial and medicinal usage, and antimicrobial activities against bacteria, fungi, and viruses.