Introduction: Consuming a plant-based diet is associated with a lower risk of cardiometabolic disorders and lower greenhouse gas emissions. Furthermore, a vegetarian diet is considered a healthy dietary pattern according to the U.S. Dietary Guidelines for Americans and strongly aligns with the 2021 AHA Dietary Guidance. Yet, little is known about current barriers to adhering to this dietary pattern. Methods: Adults who were either currently consuming or interested in consuming a plant-based diet were eligible to participate in an interview to assess behavioral, normative, and control beliefs related to consuming a plant-based diet. Participants were recruited using flyers distributed via social media (Facebook), an e-newsletter, a farmer’s market, and on the Johns Hopkins University campus, and by word of mouth. Interviews were conducted in person or via videoconference in July and August 2023 with a semi-structured guide, audio recorded, transcribed, and coded using NVivo software. Results: The study sample consisted of 12 participants who ranged in age from 21 to 62 years, 58% were women, 75% were white, and 17% were Asian American. Participants self-identified as vegan, vegetarian, or consumers of other types of plant-based diets, and had been following this dietary pattern for a long duration, ranging from 2 to 38 years. Reasons for consuming a plant-based diet were related to ethics (animal rights), the environment (desire to reduce environmental impact of their diet), health (prevent or manage disease and to lose or maintain weight), and culture (being raised in a vegetarian community). Many participants mentioned being influenced by books they read to consume a plant-based diet. Participants were largely surrounded by supportive friends, family, and partners who prepared and consumed plant-based meals with them. Barriers to consuming plant-based diet were related to accessibility particularly when traveling and when eating out (restaurants, work events) and taste of certain plant-based foods. Meat and dairy alternatives were common components of plant-based diets. Conclusion: The factors that influence adherence to a plant-based diet are informative for promoting a heart healthy and environmentally low-impact dietary pattern, consistent with current dietary guidance.