Teardrop Section Kagome trusses array can be a spoiler for a new generation of advanced combustion chambers. In this study, multi-objective optimizations are applied to optimize a jet impingement composite cooling structure with cross-flow. Four structural parameters with five levels and three performance parameters are calculated in design of experiment and fitted by response surface methodology. The database is expanded by non-dominated sorting genetic algorithm-II, and then technique for order preference by similarity to an ideal solution is used to calculate the optimal structures under different operating conditions by different weights of the performance parameter. The conclusions are as follows: The minimal Equality of variances and fitting accuracy are 35.4371 and 93.6%. Diameter of the cross-section has the largest positive main effect on average Nusselt number and pressure loss coefficient, while angle between the rod and the horizontal plane has the largest positive effect on temperature uniformity coefficient. The interaction of trailing edge angle with angle between the front rod and the back rod in the horizontal plane is large. Case15 is chosen, where the weight ratio is 1:5:5, improvement of the corresponding optimized performance parameters of the simulation results with respect to the Origin of three performance parameters are 26.72%, −2.93%, 91.59% respectively. It provides a feasible reference for future advanced combustion chambers and accelerates their development process.
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