It’s hard to keep all things angiogenic in one JAR! Journal of Angiogenesis Research has become “Vascular Cell“. “All things angiogenic” could mean many things to the many different types of researchers in the field. This diversity of thought is clearly reflected by the articles presented since the launch of the Journal of Angiogenesis Research (JAR) just over a year ago. Clinicians, scientists and educators have used the open access journal JAR, to present a variety of studies and concepts related to angiogenesis. Over the last year, JAR has presented reviews on Notch ligands found in vessels [1], Wnts in the brain vasculature [2], endothelial cell function of relevance to the cardiologist [3], and imaging paradigms to study and diagnose diseases of the vasculature [4]. Research reports on contraceptive-induced angiogenesis [5], on novel angiogenic regulators [6], and on capillary size and vascular permeability [7] represented some of the most highly accessed articles published in JAR. The field is large, diverse, exciting, and fast-paced. With notable ease, the field bridges the disciplines of medical diagnosis and treatment with that of fundamental scientific discovery. The field is relevant; serving as the basis of development of new drugs that are being used to treat cancer patients; those suffering from vision loss, diabetics, and those with other illnesses. As a result of this diversity of thoughts, of research topics, and of researchers, we came to realize that all things angiogenic/vascular could not be kept in one single JAR! The publication platform, developed as a venue for angiogenic researchers, was found to be relevant and of interest to researchers studying the many facets of human vasculature, not limited to those who study the construction of new vessels. Journal of Angiogenesis Research has grown into new areas and new frontiers of research. Our stated aim was “to publish articles from all areas of the ‘broad spectrum’ of vascular research and from the bench to the bed-side” (September 2009). To best achieve this aim, we here present a new name for the journal, Vascular Cell. Vascular Cell will focus on the vasculature in health and disease. Appreciated by the earliest anatomists and physicians, the vasculature is now being redefined. The vasculature is a dynamic structure that is built and rebuilt. Although early researchers focused on endothelial cells and started with a limited knowledge of “perivascular” cells, the vasculature is built from a wide variety of cell types and influenced by an even wider array of cells. The last decade of vascular research has been exemplified by a wider appreciation of what the vasculature is and of what it is made up of. We learned that endothelial cells come from several sources, even pathologically mutated cells! We learned that the human vasculature can be influenced by immune cells, nervous system cells, endocrine cells; in short, cells from all types of tissues. Contemporary research seeks to understand how these diverse cell types integrate signals to generate a functional vasculature. Diseases of the vasculature will be better understood, and hopefully better treated, by studying all cells of the vasculature. In the spirit of this broader definition of the vasculature, the new name represents an essentially broader focus for the journal. We hope that Vascular Cell serves as the venue to present timely research and thought on the multi-faceted vasculature in the 21 century. Vascular biology including angiogenesis research is one of the fastest expanding fields in biomedical research. Almost all developmental processes are coupled to vascular growth, remodeling and functions. Structural or functional defects of the vascular network are tightly linked to the onset, development and progression of various human diseases including those most common and lethal disorders such as cancer, cardiovascular disease, obesity, metabolic disorders and chronic inflammation. While major scientific journals such as Cell and Nature series cover other rapidly developing fields, including immunology, neuroscience, stem cell, cancer and infection, vascular biology has not been highlighted as a major field standing on its own. Our goal is to establish Vascular Cell as one of the top * Correspondence: jkk9@columbia.edu Columbia University Medical Centre, Columbia New York, USA Full list of author information is available at the end of the article Kitajewski et al. Vascular Cell 2011, 3:1 http://www.vascularcell.com/content/3/1/1 VASCULAR CELL