For the accurate estimation of daily influent total nitrogen of sewage plants, a novel hybrid approach is proposed in this study, where a gradient-based optimization (GBO) algorithm is employed to adjust the hyper-parameters of an adaptive neuro-fuzzy system (ANFIS). Several benchmark methods for optimizing ANFIS parameters are compared, which include particle swarm optimization (PSO), gray wolf optimization (GWO), and gradient-based optimization (GBO). The prediction accuracy of the ANFIS-GBO model is evaluated against other models using four statistical measures: root-mean-squared error (RMSE), mean absolute error (MAE), and Nash–Sutcliffe efficiency (NSE), and coefficient of determination (R2). Test results show that the suggested ANFIS-GBO outperforms the standalone ANFIS, hybrid ANFIS-PSO and ANFIS-GWO methods in daily influent total nitrogen prediction from the sewage treatment plant. The ANFIS, ANFIS-PSO, ANFIS-GWO, and ANFIS-GBO models are evaluated using seven distinct input combinations to predict daily TNinf. The results from both the testing and training periods demonstrate that these models, namely ANFIS, ANFIS-PSO, ANFIS-GWO, and ANFIS-GBO, exhibit the highest level of accuracy for the seventh input combination (Qw, pH, SS, TP, NH3-N, COD, and BOD5). ANFS-GBO-7 reduced the RMSE in the prediction of ANFIS-7, ANFIS-PSO-7, and ANFIS-GWO-7 by 21.77, 10.73, and 6.81%, respectively, in the test stage. Results from testing and training further demonstrate that increasing the number of parameters (NH3-N, COD, and BOD) as input improves the models’ ability to make predictions. The outcomes show that the ANFIS-GBO model can potentially be suggested for the daily prediction of influent total nitrogen (TNinf) in full-scale wastewater treatment plants.
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