Abstract Introduction: Subclavian steal syndrome (SSS) is primarily due to occlusion or stenosis of the innominate or proximal subclavian artery (SA). Subclavian artery aneurysm (SAA) is a rare type of peripheral vascular aneurysm. SAA inducing SSS is rare and only three case reports have been described in the literature. In our case, we document a large SAA located at the origin of vertebral artery that induced SSS. Patient concerns: A 65-year -old woman complained about repeated vertigo over the past 6 months. Her past history was significant for hypertension over 15 years and the blood pressure was not well controlled. Diagnosis: The computed tomography angiography showed a true SAA of size 4.2cmx3.8 cm. The transcranial Doppler showed reverse flow during systole and forward flow in diastole. Combined with the clinical manifestation and auxiliary examination, we diagnosed the patient with SSS induced by SAA. Interventions: The patient was treated with conventional blood pressure control and underwent aneurysmectomy and bypass surgery via right supraclavicular incision. Outcomes: After the surgery, the patient recovered successfully without any complications and the symptom of vertigo disappeared. During the 6-month follow-up period, her clinical condition remained stable. Conclusion: SAA causing SSS is very rare and is an often-overlooked cause of vertigo. Hence, when patients suffer from vertebrobasilar insufficiency such as vertigo or walking instability, examinations using ultrasonography, transcranial Doppler and even computed tomography angiography are necessary to exclude the complications caused by SAA and SSS.
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