Introduction: Competency-based medical education (CBME) emphasizes outcome-based learning evaluation and assessment. Objective Structured Practical Examination (OSPE) is a valid, reliable, and objective tool suggested in the anatomy curriculum. OSPE modules were developed and implemented in anatomy for first-year MBBS Students, and the perception of first-year MBBS students about OSPE was studied. Methods: This study was conducted on 50 MBBS students of the 2021 admission year in the Department of Anatomy after approval from the Institutional Ethics Committee. Feedback survey questionnaires were prepared and validated by the subject experts and MEU members to study students' perceptions of OSPE. Students' perceptions were noted on a 5-point Likert scale. Data was entered through Google Forms and analyzed. Results: 93.2% of students believed that OSPE made learning competencies easier for them. Only 13.7% of students felt that time devoted to OSPE assessment was inadequate. 79.6% of students were of the opinion that It made them confident in all aspects of addressed competencies. 88.6% of students felt that OSPE improved their ability to demonstrate knowledge and skills of addressed competencies. 88.6% of students were of the view that OSPE is a satisfactory method of assessing their capabilities as a student. 83.7% of students ' opinion was that it would help them in learning the competencies of Anatomy. In the opinion of 93.2% of students, OSPE should be a regular method of assessment. 81.8% of students agreed that OSPE was a feasible exercise. Conclusions: The study concluded that implementing OSPE as a method of assessment in Anatomy for first-year MBBS Students is feasible and acceptable. 93 percent of students believe this method makes learning competencies easier for them. KEYWORDS: OSPE, Assessment, Anatomy, Perception, Competency, Curriculum.