Experimental vapor heat (VH) tests [43.5C for 5 hours, 1009” relative humidity (RH)] were conducted to determine treatment effects to freshly harvested Florida grapefruit (Citrus paradisi Macf.). VH treatment reduced peel pitting 5-fold compared to control fruit after 5 weeks of storage (4 weeks at 10C + 1 week at 21C) and did not cause peel discoloration or rind breakdown. There was no difference in volume between treated and nontreated fruit after 1 week of storage or in weight loss after 5 weeks. Also, peel color, total soluble solids concentration, acidity, and pH were not affected by VH treatment. Fruit were slightly less firm after VH treatment and remained less firm throughout storage, compared with control fruit. The VH treatment tested is a potentially viable alternative quarantine treatment for control of the Caribbean fruit fly [Anastrepha suspensa (Loew)] because it is not phytotoxic to grapefruit and has been reported effective for disinfestation of this pest in grapefruit.