Analytical Monitoring System Research Articles

Time-dependent networks for the treatment of acute coronary syndrome in South East Tuscany

Abstract Introduction The importance of timely reperfusion therapy in Cardiovascular diseases is crucial, leading to the creation of time-dependent networks for Acute Coronary Syndrome treatment. The ACS-STEMI treatment network in Tuscany operates across three health authorities (LHAs),including South-East Tuscany. The network ensures ACS-STEMI treatment in 12 hospitals integrating new territories such as Piombino and Elba into the network. Aim of the study is to assess the impact of an analytical monitoring system of the times to reperfusion treatment and the actions to improve the performance of the network. Methods In this retrospective study an analytical evaluation of the network’s performance was conducted. We utilized data on patient transport, symptom onset to medical contact times, and outcomes from the National Outcomes Program (PNE).Analytical evaluations in 2021 measured the network’s performance, identifying main delay causes. The treatment process is divided into periods from symptom onset to coronary reperfusion, and interventions like public campaigns, ECG transmission and fast-track transfers have been implemented. Results South East Tuscany LHU had the lowest 30-day mortality rate for ACS patients in Italian hospitals with 300 cases annually in 2020 and 2021.Improvements continued into 2022 and 2023, further reducing mortality rates in patients initially admitted to SPOKE hospitals. For Piombino and Island of Elba residents,30-day mortality decreased from 8.8% (2017-2020) to 5.7% in 2022. The Grosseto hub treated 80% of STEMI patients within 90 minutes in 2022. Conclusions The establishment of a well-organized time-dependent network for ACS-STEMI treatment in Tuscany has significantly improved patient outcomes, demonstrating the critical role of timely and efficient care pathways. The network’s success is attributed to several factors, including improved accessibility, enhanced coordination among healthcare facilities, and effective use of technology and resources. Key messages • Treatment networks for ACS/STEMI can improve health outcomes in peripheral areas. • Structured clinical-care pathways in delivering high-quality care for ACS patients reduces ACS mortality.

ВЛИЯНИЕ ПРОЦЕССОВ ЦИФРОВИЗАЦИИ НА ИНСТРУМЕНТЫ МОНИТОРИНГА УГРОЗ ЭКОНОМИЧЕСКОЙ БЕЗОПАСНОСТИ

The article examines digital monitoring tools that are used to identify risks and threats to economic security. The effectiveness of existing monitoring systems is analyzed, shortcomings related to the regular modernization and improvement of cybercrime is highlighted. Examples of the implementation of analytical monitoring systems by state regulatory structures are considered and their role in the system of economic security is determined. Analysis of the effectiveness of various monitoring systems has shown that a combination of multidirectional tools allows for the best results in identifying threats to economic security.

Web-Based Information and Analytical Monitoring System Tools – Online Visualization and Analysis of Surface Water Quality of Mining and Chemical Enterprises

Web-Based Information and Analytical Monitoring System Tools – Online Visualization and Analysis of Surface Water Quality of Mining and Chemical Enterprises

Design, Development, and Analysis of an Automated Sampling Loop for Online Monitoring of Chiral Crystallization.

Enantiomeric purity is of prime importance for several industries, specifically in the production of pharmaceuticals. Crystallization processes can be used to obtain pure enantiomers in a suitable solid form. However, some process variants inherently rely on kinetic enhancement (preferential crystallization) of the desired enantiomer or on complex interactions of several phenomena (e.g., attrition-enhanced deracemization and Viedma ripening). Thus, a process analytical technology able to measure the enantiomeric composition of both the solid phase and the liquid phase would be valuable to track and eventually control such processes. This study presents the design and development of a novel automated analytical monitoring system that achieves this. The designed setup tracks the enantiomeric excess (ee) using a continuous closed-loop sampling loop that is coupled to a polarimeter and an attenuated total reflection Fourier transform infrared spectroscopy spectrometer. By heating the loop and alternately sampling either the liquid or the suspension, the combination of these measurements allows tracking of the ee of both the liquid and the solid. This work demonstrates a proof of concept of both the experimental and theoretical aspects of the new system.

ОСОБЕННОСТИ ФОРМИРОВАНИЯ И РАЗВИТИЯ ИННОВАЦИОННОЙ СИСТЕМЫ РЕГИОНА

Problems and possibilities of innovation system development of the Bryansk region by means of inte-raction intensifying of business and higher education institutions are considered. Relevance of the idea of higher education institution transformation into full-fledged participants of innovation process is estimated. On the one hand, they act as organizations for higher education training, on the other hand - as organizations creating emergence, introduction and diffusion of in-novation. Scientific approaches to formation of as-sessment techniques of innovation infrastructure are analyzed. A specific feature of author's technique consists in using statistics, indicators of analytical Monitoring system of the Ministry of Education and Science of the Russian Federation, and calculation tools of area graphs characterizing state assessment of innovation infrastructure of the region in 2010-2015, influence extent of each factor on region GRP. The author's technique solves assessment problem of not only current state of innovation infrastructure of the region, but also allows to define the greatest and smallest influence of factors on the development of this or that type of infrastructure in a certain time interval.

Вдосконалення програмних компонентів аналітичних моніторингових систем

The main issue that has been considered in this scientific article is the perfection of software components of analytical monitoring systems by means of implementation of stored procedures, which are separate software modules, combining several queries with logical operations on the data obtained and stored in the database after a single installation. The article describes the issues, concerning the distribution of the load on the system by means of the transfer of the maximum possible number of logical operations to stored procedures as well as basic concepts and syntax which is used to write stored procedures in PL / SQL and call the procedure test sample in java language in which one should specify the name and parameters of the procedure for referencing the database through previously established connection. It also describes the possibility to access the procedure by a certain number of users from different applications at the same time and prevent unauthorized interference into the database, controlling users’ access to stored information, giving them the rights in accordance with the requirements set by the system administrator.

Analytical monitoring systems based on photocatalytic oxidation principles

Under photocatalytic oxidation, an organic compound in water can be quantitatively converted to ions corresponding to the elemental composition of the compound. Based on this principle, a range of analytical monitoring systems can be constructed for selective monitoring of organic pollutants containing these elements in aqueous systems.

Characteristics and distributions of ester groups in propylene glycol alginates

The nature of the ester groups in propylene glycol alginate (PGA) has been investigated by 13C-NMR spectroscopy and chemical saponification studies. Two types of ester, namely primary 2-hydroxyprop-1-yl and secondary 1-hydroxyprop-2-yl, were detected by 13C-NMR spectroscopy by virtue of the methyl carbon resonances. From model compound studies the two forms were shown to be due to the type of ester present and not to the type of sugar residue (β- d-mannuronic or α- l-guluronic acid) to which the ester may have been bound. Alkaline saponification studies using a variety of analytical monitoring systems, and model compounds, has shown that the two types of ester exist in an equilibrium with the more thermodynamically favourable primary ester predominating in the ratio 4:1. The nature of the sugar residues, namely β- d-mannuronic and α- l-guluronic acid, to which the esters were bound, did not have any bearing on the rate of ester hydrolysis. The rate of hydrolysis of ester groups in PGA was, however, dependent upon the nature of the ester groups present, namely primary or secondary. On the basis of the evidence presented, the thermodynamically more stable primary ester predominates in PGA, as would be expected from the preparation conditions.