Europe is considered one of the most attractive and safe prevalent tourist destinations in the entire world. Approximately half (47.4%) of European tourist visits occurred in coastal regions, defined "on the basis of and consist of local administrative units or municipalities that border the sea, or have at least half of their total surface area within a distance of 10 km from the sea." Destinations such as Malta, Greece, Cyprus, Spain and Croatia presented with an increased level of tourist accommodation establishments, as well as, the overall flow of tourism in the European Union is mostly concentrated on Mediterranean coastal regions (as nine out 10 tourists, in 2015, spent their holidays at coastal areas). This paper, is dealing with the assessment of a tourist area and how the concept of urban metabolism has been affected by touristic activities. Moreover, this research using several key performance indicators such as waste compositional analysis, the clean coast index, the accumulation rate, and accumulation index, etc., tries to measure the level of environmental performance, and furthermore, to assess the existing infrastructures and the waste management plan, that are being implemented. The results are very useful, for any policy-maker, as well as competent authorities and/or tourist organizations which are dealing with tourist activities and aim to propose or re-schedule any waste strategy targeting the goals of United Nations Sustainable Development Goals, European Green Deal, and the new circular economy strategy.