Slope Analyses Research Articles

Physical Activity Influences the Relationship between Objectively Measured Hot Flashes and Endothelial Function in Perimenopausal Women

Hot flashes (HF) are disruptive symptoms experienced by approximately 80% of women undergoing menopause. The transition to menopause is associated with increases in CVD risk factors. The frequency and severity of HF have been associated with poorer cardiovascular health but most of these studies have quantified HF by self-report and have not considered physical activity (PA), known for its cardiovascular benefits. The association between HFs and CVD risk may be through their effect on endothelial health. The objective of this study was to evaluate the relationship between objectively measured HF and endothelial function and determine the effect of physical activity on the relationship in healthy perimenopausal women. We hypothesized that more HF would be associated with lower endothelial function and PA would influence this relationship. Healthy perimenopausal women (n=52, age 43-54) were included in this analysis. Perimenopause was defined as ≥7d difference in the length of consecutive cycles to <12 months of amenorrhea. Hot flashes were measured objectively using sternal skin conductance for 24 hours. The number of HF experienced and HF rate (normalized to actual wear time) were quantified. Endothelial function was assessed with measures of brachial artery flow mediated dilation (FMD, %) on the non-dominant arm. Moderate to vigorous physical activity (MVPA) was assessed with 7-days of actigraphy monitoring on the non-dominant wrist. The R package GGIR and Hildebrand (2016) cut points were used to quantify PA intensity and reported as sum of the average minutes of moderate and vigorous physical activity per day. Pearson correlations and multiple regression analyses were used to evaluate relationships between variables. Data met all assumptions for statistical tests. Modeling was performed to evaluate whether HFs were predictors of the main outcome of FMD (R version 4.2.3 and RStudio version 2023.06.2+561). Age and BMI were included in all models. Lower FMD was significantly correlated with a higher objective HF rate ( r (52) =-0.27, p=0.05). Objective HF rate predicted FMD (β=-3.91, p=0.04) when controlling for age and BMI (adj R2=0.100, F(3,48) =2.892, p=.05). When MVPA was added to the model, MVPA alone was not a significant predictor but the interaction between MVPA and HF was (β=0.12, p=0.04; adj R2=0.147, F(5,46) =2.761, p<0.03). This interaction was such that higher levels of MVPA were related to a less strongly negative relationship between objective HF rate and FMD. A simple slopes analysis found that the HF rate effect at one SD below the mean MVPA was significantly negative, (β=-8.64, p=0.004), whereas the HF rate effect at one SD above the mean MVPA was not significant, (β=0.18, p=0.95). These data provide strong evidence that support the hypothesis that a greater number of objectively-assessed hot flashes is associated with lower endothelial function in perimenopausal women and that higher amount of physical activity serves as a buffer against the negative relation between hot flashes and FMD. NIH NHLBI R15 Grant 1R15HL145650-01A1 (Witkowski); Smith College McKinley s Honors Fellowship (Tha Ra Wun); Smith College STRIDE (Buszkiewicz). This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Posttraumatic stress disorder, insomnia, depression, and healthrelated quality of life in Chinese soccer players: Resilience as a moderator

This study examined the relationships among posttraumatic stress disorder (PTSD), insomnia, depression, and health-related quality of life (HRQoL) in Chinese soccer players, and investigated the moderating role of resilience in these relationships. Respondents (n = 356) completed the Short-Form PTSD Checklist-5, Insomnia Severity Index, Patient Health Questionnaire-9, 12-Item Short Form Health Survey, and Connor-Davidson Resilience Scale. Structural equation and simple slope analyses were performed using SPSS 26.0 and Amos 26.0. The results showed that PTSD had a significant negative impact on HRQoL in soccer players. Insomnia and depression acted as chain mediators between PTSD and HRQoL, and resilience inversely moderated the effects of insomnia on depression, as well as attenuating the negative impact of depression on HRQoL. These findings provide a theoretical basis for relevant government departments, experts, and coaches to develop and adopt effective interventions.

Hedonic hunger, ultra-processed food consumption, and the moderating effects of impulsivity in pregnant individuals with body mass index ≥ 25

Evidence suggests higher hedonic hunger (preoccupation with/desire to consume food for pleasure) is associated with greater ultra-processed food (UPF) consumption in non-pregnant individuals with higher, but not lower, self-report impulsivity or delay discounting. The current study tested the association between hedonic hunger and UPF consumption, and the moderating effects of self-report impulsivity and delay discounting, during pregnancy. Individuals (N = 220) with body mass index (BMI)≥25 completed the Power of Food Scale, 24-h dietary recalls, and Barratt Impulsiveness Scale-Version 11 in early-mid pregnancy. A subset enrolled in an ancillary study (n = 143) completed a Delay Discounting Task. Linear regression and moderation models covaried for age, gestational age, pre-pregnancy BMI, and socioeconomic status. The association between hedonic hunger and UPF consumption was nonsignificant (p = 0.47). Self-report impulsivity was not a significant moderator (p = 0.11), but delay discounting was (p = 0.01). Simple slopes analysis revealed a one-unit increase in hedonic hunger was associated with 7% lower UPF intake among participants with lower (M+1SD) delay discounting (p = 0.01) and 1% higher UPF intake among those with higher (M-1SD) delay discounting (p = 0.57). Findings contrast those from research with non-pregnant samples and indicate lower delay discounting may serve as a protective factor, associated with reduced UPF consumption at higher levels of hedonic hunger, during pregnancy.

A novel bidentate diamide ligand DODQ for the separation of uranium and rare earth ions in nitric acid medium

High efficiency extractants play a necessary role in the selective removal of uranium from rare earth minerals. In this paper, a novel cyclic bidentate diamine extractant, 1, 4-dioctyl-1, 4-dihydroquinoxaline-2, 3-dione (DODQ), was synthesized, and the complexation and extraction of UO22+ in nitric acid medium were systematically studied. The results indicate that DODQ exhibits a unique combination of properties in removing UO22+, with an extraction capacity 132 times higher than that of DODPhOA (acyclic structure). Extraction isotherm experiments and slope analyses illustrate the formation of a 1:1 DODQ/UO22+ regime during the extraction process. Electrospray mass spectrometry, fluorescence spectroscopy, and X-ray crystal diffraction analyses further corroborated its stoichiometric properties. In addition, DODQ can remove UO22+ from rare earth solutions containing UO22+ with high selectivity. This study provides an alternative method to separate uranium from the leaching solution of rare earth ore and has a new understanding of the coordination and complexing behavior of UO22+ with bidentate oxygen-containing ligands.

Savoring changes novel positive mindset targets of GAD treatment: Optimism, prioritizing positivity, kill-joy thinking, and worry mediation

This study analyzed effects of savoring on unstudied positive mindset targets of generalized anxiety disorder (GAD) treatment (ClinicalTrials.gov: NCT05040061). 85 students with GAD were randomly assigned to one of two ecological momentary interventions (EMIs) on smartphone for seven days. The SkillJoy EMI promoted practices for savoring positive emotions. An active control EMI mirrored SkillJoy, yet did not include savoring or positive emotion. Optimism, worry, kill-joy thinking (lessening positive emotion with cognition), and prioritization of positive emotion activities and goals were assessed at pre-trial, eighth-day, post-trial, and 30th-day follow-up. Savoring was assessed pre-trial and fifth-day mid-trial. Longitudinal linear mixed models and simple slope analyses examined change between and within conditions. Bias-corrected bootstrapping path analysis examined mediation of worry change by increased savoring. SkillJoy led to significantly greater increases in both optimism and prioritizing positivity than the control from pre-trial to post-trial and pre-trial to follow-up. Both interventions significantly reduced kill-joy thinking at both timepoints with Skilljoy leading to marginally greater change at post-trial. Pre- to mid-trial increases in savoring mediated the relationships between treatment condition and reductions in worry at both post-trial and follow-up.

Holistic Review of Applicants by the United States Postgraduate Training Programs Is Not Associated With the Percentage of Female Residents.

Introduction Given the underrepresentation of female physicians in most specialties and the aim of holistic review in residency applicationsto improve the diversity of matriculating resident physicians in the United States (US) postgraduate medical training programs, we examined the association between holistic review and female resident representation among US postgraduate training programs. Methods We conducted a cross-sectional survey of US postgraduate training programs to inquire about their use of holistic review for resident applications (independent variable). The primary outcome was the percentage of female residents in each program, which was obtained along with other program-level characteristics from the Fellowship and Residency Electronic Interactive Database Access (FREIDA) catalog in April 2023. We limited the analysis to the 10 specialties with the most training spots in 2022, including anesthesiology, emergency medicine, family medicine, internal medicine, neurology, obstetrics and gynecology, orthopedic surgery, pediatrics, psychiatry, and surgery (general). We also examined the interactions between holistic review and specialtyand the percentage of female facultyusing model comparison and simple slopes analyses. Results Of the 3,364 total programs surveyed from the 10 specialties, 222 (6.6%)responded. Responders and nonresponders had similar program-level characteristics, including program type (e.g., university, community), specialty, and reported minimum board examination scores. Of the 222 responders, 179 (80.6%) reported performingholistic review. The percentage of female residents was 49.0% (interquartile range 37.5 to 66.7) in the no holistic review group and 47.8% (35.4 to 65.0) in the holistic review group (median difference 0.9%, 95% confidence interval -6.7 to 8.3). Furthermore, there was no evidence of interaction between holistic review and either the specialty or the percentage of female faculty on the outcome of the percentage of female residents. Conclusions Holistic review of residency applications in this limited sample of US postgraduate training programs was not associated with the percentage of female residents. The role of holistic review in addressing the imbalance of male and female physicians in the healthcare workforce, particularly between specialties, remains unknown.

Vision problems and positive youth development: The mediating role of vision-related quality of life and the moderating role of self-control

BackgroundVision problems are still widespread among children and adolescents in rural areas of China. Previous studies on the effects of vision problems on adolescent development have mostly focused on the effects of vision problems from a negative and problematic perspective, but the associations of vision problems with adolescent development potential and resources and potential mediating and moderating mechanisms are unclear. In this study, we investigated thepotentialmediating effects of vision-related quality of life (VR-QoL) and the potential moderating effects of self-control in the relationship between vision problems and positive youth development (PYD). MethodsUsing a two-stage sampling method, 2,837 students in grades 7–9 at five middle schools in four townships in Zhenping County, Henan Province, completed self-report questionnaires that included measurements of vision problems, PYD, VR-QoL and self-control as well as covariates such as sex. The relationships among variables were analysed with a moderated mediation model using the PROCESS macro of SPSS. ResultsThe total effect and direct effect of vision problems on PYD were not significant, but PYD was predicted negatively by the emotional dimension of VR-QoL. VR-QoL may fully mediate the association between visual problems and PYD. The moderated mediation analysis results showed that self-control enhanced the positive effect of the emotional dimension on PYD. Simple slope analyses indicated that the emotional dimension positively predicted PYD at a high level of self-control, while the emotional dimension did not significantly predict PYD at a low level of self-control. ConclusionThe present study revealed the relationship between vision problems and PYD and related mechanisms. Vision problems affected PYD through VR-QoL, and the mediating effect was greater in adolescents with high levels of self-control.

Associations between cerebellar development and autistic traits during adolescence: a population-based cohort study

IntroductionBrain maturation is associated with adolescent socio-cognitive development. The lateral posterior region of the cerebellum plays a critical role in higher cognitive processes, and deviations of this region are associated with autism-related behaviors. Hence, it is plausible that developmental changes in this region of the cerebellum during adolescence are different along a variation in autistic traits. Additionally, its difference may be moderated by parental age at birth and weight growth during infancy, which have effects on brain development.ObjectivesThe aim of this study was two folds: (1) to test whether cerebellar development during adolescence is different along a variation in autistic traits (2) to test whether parental age at birth and weight growth during infancy moderate the results of (1).MethodsLongitudinal study was conducted over a 6-year period with 256, 230 and 187 participants ranging from 10.5 to 17.6 years, observing adolescent development respectively at 2-year time periods. We undertook a detailed investigation into differences in the lateral posterior region of the cerebellum volume. The 50-item Autism-Spectrum Quotient (AQ) was rated by primary parents. Weight growth and parental age were evaluated using maternal and child health handbook records. A multiple regression analysis was performed to examine whether AQ subscales, sex, and their interactions affected cerebellar development. Moderation analysis assessed whether parental age and weight growth moderated associations between cerebellar development and autistic traits. All participants provided written informed consent, and the study was approved by the Ethics Committee (No.10069).ResultsInteractions between sex and attention switching and sex and attention to detail were significantly associated with cerebellar development in the bilateral gray matter (GM) and white matter (WM) of Crus I and Crus II (Fig1, 2). Simple slope analyses showed that the slopes of cerebellar development were significant for girls (pFDR < 0.001). Although no significant interaction was found between them, the main effect of attention to detail was significantly associated with cerebellar development in WM of VIIB (pFDR = 0.006). Further, moderation analysis found that the association between the cerebellar development and autistic traits were significantly moderated by maternal age; the magnitude of its effect was significant for high maternal age in boys (pFDR = 0.036, Fig3). Paternal age, early (0-9 months) and late weight growth (4-18 months) also moderated associations between them, however, no significance remained after FDR controlling.Image:Image 2:Image 3:ConclusionsThere are significant associations between cerebellar development during adolescence and autistic traits, and its pattern of association can be moderated by parental ages at birth and weight growth during infancy in a cerebellar region- and sex-specific manner.Disclosure of InterestNone Declared

Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging

Neuroimaging studies often quantify tau burden in standardized brain regions to assess Alzheimer disease (AD) progression. However, this method ignores another key biological process in which tau spreads to additional brain regions. We have developed a metric for calculating the extent tau pathology has spread throughout the brain and evaluate the relationship between this metric and tau burden across early stages of AD. 445 cross-sectional participants (aged≥50) who had MRI, amyloid PET, tau PET, and clinical testing were separated into disease-stage groups based on amyloid positivity and cognitive status (older cognitively normal control, preclinical AD, and symptomatic AD). Tau burden and tau spatial spread were calculated for all participants. We found both tau metrics significantly elevated across increasing disease stages (p<0.0001) and as a function of increasing amyloid burden for participants with preclinical (p<0.0001, p=0.0056) and symptomatic (p=0.010, p=0.0021) AD. An interaction was found between tau burden and tau spatial spread when predicting amyloid burden (p=0.00013). Analyses of slope between tau metrics demonstrated more spread than burden in preclinical AD (β=0.59), but then tau burden elevated relative to spread (β=0.42) once participants had symptomatic AD, when the tau metrics became highly correlated (R=0.83). Tau burden and tau spatial spread are both strong biomarkers for early AD but provide unique information, particularly at the preclinical stage. Tau spatial spread may demonstrate earlier changes than tau burden which could have broad impact in clinical trial design. This research was supported by the Knight Alzheimer Disease Research Center (Knight ADRC, NIH grants P30AG066444, P01AG026276, P01AG003991), Dominantly Inherited Alzheimer Network (DIAN, NIH grants U01AG042791, U19AG03243808, R01AG052550-01A1, R01AG05255003), and the Barnes-Jewish Hospital Foundation Willman Scholar Fund.

Childhood trauma and psychopathy: The moderating role of resilience.

Despite accumulating evidence of significant albeit moderate associations between childhood trauma and psychopathy, little is known about the potential moderators of these associations. To advance knowledge in this area, the present study investigated the moderating role of resilience in the childhood trauma-psychopathy link. A community sample of 521 adult participants from the Netherlands (40.1% men; Mage = 35.27 years, SD = 15.99) completed two self-report questionnaires measuring psychopathic personality traits: a self-report measure of resilience and a retrospective measure of childhood traumatic experiences. Correlation analyses were employed to investigate bivariate associations among study variables. Moderated multiple regression analyses with bootstrapping followed by simple slope analyses were employed to examine Childhood Trauma × Resilience interactions in predicting scores of psychopathy subscales. Childhood trauma had small positive associations with psychopathic traits across the board, with the exception of a small negative association with boldness traits, as well as a small negative association with resilience. Resilience was strongly and positively related to boldness, and negatively related to affective (callousness, meanness) and behavioral (antisocial, disinhibition) traits of psychopathy. Resilience moderated six out of seven associations between childhood trauma and psychopathic traits. Resilience appeared to represent a significant buffer in the associations between childhood traumatic experiences and psychopathic traits, such that these associations became weaker and nonsignificant (and even negative for boldness) at higher levels compared to lower levels of resilience. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Posttraumatic Stress and Alcohol Use Among Hispanic/Latinx University Students: A Moderated Indirect Effect Model of Coping-Related Drinking and Anxiety Sensitivity

Objective Posttraumatic stress symptoms (PTSS) and anxiety sensitivity (AS) are associated with increased alcohol use and coping-motivated drinking among university students. This study among trauma-exposed Hispanic/Latinx university students sought to examine the indirect effect of PTSS on alcohol use severity through coping-motivated drinking and test the moderating role of AS and AS subfacets. Methods University students who identified as Hispanic/Latinx (N = 830) were recruited from a large, urban, southern university and completed online, self-report questionnaires. Results A significant interactive effect of PTSS and AS on coping-motivated drinking emerged. PTSS exerted a significant indirect effect on alcohol use severity, through coping-motivated drinking. Simple slope analyses revealed that PTSS was associated with coping-motivated drinking across all levels of AS. Post hoc results revealed unique biological sex differences in probable diagnosis odds ratios. Conclusions These findings indicate that PTSS and AS are associated with coping-motivated drinking and alcohol use severity in trauma-exposed, Hispanic/Latinx university students.

Associations of Kidney Tubular Biomarkers With Incident Macroalbuminuria and Sustained Low eGFR in DCCT/EDIC.

Tubulointerstitial injury contributes to diabetic kidney disease (DKD) progression. We tested tubular biomarker associations with DKD development in type 1 diabetes (T1D). We performed a case-cohort study examining associations of tubular biomarkers, measured across seven time points spanning ∼30 years, with incident macroalbuminuria ("severely elevated albuminuria," urinary albumin excretion rate [AER] ≥300 mg/day) and sustained low estimated glomerular filtration rate (eGFR) (persistent eGFR <60 mL/min/1.73 m2) in the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study. Biomarkers included KIM-1 and sTNFR1 in serum/plasma, MCP-1 and EGF in urine, and a composite tubular secretion score reflecting secreted solute clearance. We assessed biomarkers using single values, as mean values from consecutive time points, and as change over consecutive time points, each as time-updated exposures. At baseline, mean diabetes duration was 5.9 years, with mean HbA1c 8.9%, eGFR 125 mL/min/1.73 m2, and AER 16 mg/day. There were 4.8 and 3.5 cases per 1,000 person-years of macroalbuminuria and low eGFR, respectively. Assessed according to single biomarker values, KIM-1 was associated with risk of subsequent macroalbuminuria and low eGFR (hazard ratio [HR] per 20% higher biomarker 1.11 [95% CI 1.06, 1.16] and 1.12 [1.04, 1.21], respectively) and sTNFR1 was associated with subsequent macroalbuminuria (1.14 [1.03, 1.25]). Mean KIM-1 and EGF-to-MCP-1 ratio were associated with subsequent low eGFR. In slope analyses, increases in KIM-1 and sTNFR1 were associated with subsequent macroalbuminuria (per 20% biomarker increase, HR 1.81 [1.40, 2.34] and 1.95 [1.18, 3.21]) and low eGFR (2.26 [1.65, 3.09] and 2.94 [1.39, 6.23]). Serial KIM-1 and sTNFR1 are associated with incident macroalbuminuria and sustained low eGFR in T1D.

Experimental study on the effect of water-induced deterioration on shear properties of bolted rock joints

The investigation into the impact of dry and wet cycles as well as prolonged immersion on the shear properties of bolted rock joints can facilitate comprehension of the mechanism behind shear damage in anchorage rock slopes located within dam sites, which is crucial for conducting long-term stability analyses of such slopes and ensuring safe operation of hydropower plants. In this study, the sandstone from the Three Gorges reservoir area was collected and utilized to made into bolted rock joint specimens, which underwent 12 cycles of wetting and drying as well as 180 days of immersion before undergoing direct shear tests to investigate the degradation of their mechanical properties. The test results indicate that both treatments for water deterioration can significantly reduce the peak shear strength of bolted sandstone joints. The shear deformation characteristics of bolts also vary with the decrease in rock mass strength. As the number of wet and dry cycles, as well as immersion time, increases, the plastic hinge length of the bolt gradually extends. The surface roughness of the joint has an impact on the fracture mode of the bolt. In a flat joint, the fracture section of the bolt exhibits a certain inclination angle, indicating a damage mode where positive and shear stresses act in concert; whereas in a rough joint, the fracture section of the anchor rod shows almost zero inclination angle and is damaged under positive stress. Finally, an attempt was made to apply the conclusions of this paper to engineering by conducting a time-varying reliability analysis of the generalized anchored slope model. The results obtained have significant guidance for evaluating the long-term stability of anchored slopes in hydropower projects.

Evaluation of buoyant action of groundwater and surface water interaction on pit slope stability using hydrogeological-stratigraphic-structural assessment within the Kawere catchment of the Nsuta mine

ABSTRACT In open-pit mining operations where activities are conducted below water table or close to surface water bodies, the mine is potentially faced with dewatering and slope stability challenges. Appropriate evaluation of slope stability to obtain adequate slope safety factor has continuously been the centre of geotechnical research locally and internationally. This paper evaluates the influence of buoyant action propagated by groundwater and surface (GW-SW) interaction on pit slope designed in multi-layered fractured rock with complex hydrology using Hydrogeological-Stratigraphic-Structural Assessment (HSSA) at the Nsuta Manganese Mine in Ghana. LEM analyses of the Pit C-western slope estimated an overall factor of safety (FOS) of 1.1, probabilities of failure (POF) of 7.5% and the reliability index (RI) of 1.4 in the slope stress field. However, when the groundwater was introduced, the slope FOS was reduced to 0.13, POF of 100.0% and (RI) of 0.00 indicating failure. FEM numerical model points to the location of maximum shear strain and total displacement in the argillite zone within the rock mass. The FEM seepage analysis model estimated groundwater pore pressure data along the critical slide surfaces from the crest of the slope to the bottom of the rock slope ranging between 250 kPa and 4250 kPa with an average pore pressure of 2250 kPa within the pit slope. This proposed HSSA approach used in the study provides innovative insights into the percentage failure contribution of the individual lithologies to the overall combined lithological susceptibility of the slope under stress and groundwater failure mechanisms, pointing out Ru ratio in pit slope stability estimation as inadequate.

Evaluation of Thermodynamic Model of Pd(II) Complex Formation with Isosaccharinic Acid

Palladium-107 is one of the selected radionuclides in the safety assessment of geological disposal of radioactive waste. Although isosaccharinic acid (ISA) forms strong complexes with many elements and enhances element solubility, the thermodynamic evaluation of the complex of Pd with ISA has not been conducted. In this study, the solubility of Pd(OH)2 at pH 8.5–12.5 in the presence of ISA was investigated under inert gas (N2) atmosphere. Furthermore, the coordination state of aqueous Pd and ISA was investigated by X-ray absorption and Fourier transform infrared spectroscopy, respectively. According to experimental results, the number of OH ligands in the mixed complex depends on pH. The thermodynamic model and conditional equilibrium constants of the Pd-ISA complex were estimated by slope analyses of solubility experiments at different pH levels and ionic strengths based on the specific ion interaction theory. Hence, the impact of complexation with ISA on Pd(II) solubility under disposal conditions could be quantified using the proposed thermodynamic models in this study.

The Relationship Among Student-Teacher Interaction and Academic Performance of Students in Congolese Higher Education: The Moderating Role of Marital Status

The purpose of this research was to develop and validate the moderating effect of marital status on the relationship between student-teacher interaction and academic performance of students at Congolese university using two main studies. The first study was designed to develop the instruments for measuring student-teacher interaction’ and their academic performance at the university and to explore the moderating effect of marital status on the relationship between student-teacher interaction and the academic performance of students. For this study, a mixed research method was used. Samples were drawn from one higher education institutions (the University of Kinshasa), using simple random sampling and stratified random sampling techniques based on students’ status and sex as strata. For this study, both qualitative and quantitative data were collected. Data for qualitative analysis were gathered from married and unmarried students using interviews and focus group discussion, whereas data for quantitative analysis were gathered from married and unmarried students using questionnaire. The analyses were made using mainly multiple regressions, the statistical testing of the generated hypothesis via t-test statistics and Pearson product moment correlation, multivariate analysis of variance (MANOVA), and simple slope analyses. Furthermore, the demographic variable of participants (sex of students, student status, study level, socio-economic status of the family and major) was another target of the study. 362 students (include married’ and unmarried’ students) from the university of Kinshasa, took part in the study. The study was guided by the Bandura’s social cognitive theory, that determines human behavior and describe the learning theory that analyzes and explains how feelings, thoughts, actions of others, and social experiences actively shape learning processes. The final results revealed that there is a significant correlation between student-teacher interaction and academic performance. In addition, marital status moderated the relationship between student-teacher interaction and academic performance when students are unmarried.The second study was designed to examining the difference of academic performance between married and unmarried students. Qualitative data were collected from 362 students (include married’ and unmarried’ students) using interview questionnaire. Data were analysed using constant comparative approach (the reported stories that emanated from the conversations with the research participants); the deduced meanings from the interview protocol. The study results indicated that the unmarried students’ academic performance was high than their married students’ counterpart and in significant way; and the marital status was negatively associated with academic performance of students at the university in DRC. Finally, based on the findings, some practical and theoretical implications and future research directions were forwarded.

Multilevel and general linear modeling of weather and time effects on the emotional and behavioral states of children with profound intellectual and multiple disabilities.

Eliciting the emotional and behavioral states of children with severe or profound intellectual disabilities (IDs) and profound intellectual and multiple disabilities (PIMD) due to their complex and atypical developmental trajectories has become increasingly elusive. It is evident that the environment, influenced by weather conditions and time of the day, plays a pivotal role in molding children's behaviors, emotions, and interactions. This underscores the significance of the environment as a critical factor in exploring the communication dynamics of children with PIMD/IDs. Over five months during fall and winter seasons, we conducted 105 video-recorded sessions with 20 children aged 8 to 16 with PIMD/IDs. These sessions aimed to capture the emotional and behavioral states interpreted by caregivers while simultaneously collecting indoor and outdoor weather indices, location, and time data. Using cross-classified multilevel and general linear models adjusted for individual characteristics and location variability with subsequent simple slope analyses, we examined the main and seasonal interaction effects of indoor and outdoor weather indices and time of the day on the emotional and behavioral states of children with PIMD/IDs. The models revealed that higher atmospheric pressure (atm), indicative of pleasant and favorable weather conditions, was associated with increased engagement (indoor: p < 0.01; outdoor: p < 0.01) and interest (outdoor: p < 0.01) behaviors. In contrast, engagement levels decreased before lunchtime (p < 0.01; p < 0.001), and inclement or unstable weather conditions characterized by low-pressure systems (p < 0.05) and stronger wind speed (p < 0.05) led to more refusal or disagreement. During winter, children displayed significantly more agreement with their caregivers (p < 0.001). Interestingly, they also engaged more on cloudy days (p < 0.05). Furthermore, simple slope analyses revealed that high atm conditions in fall were linked to more engagement (p < 0.05) while humid conditions predicted more assent behaviors (p < 0.001). However, cloudy weather predicted less attentional focusing (p < 0.05) and interest (p < 0.01) behaviors in winter. This study confirms that fluctuations in weather indices, including seasonal changes and time of the day, can provide potential pathway indicators and supplement behavioral observations to elicit the behavioral states of children with PIMD/IDs. These findings highlight the importance of considering these factors when designing meaningful interactions and communication interventions for this population.

Parenting styles and personal belief in a just world among Chinese children and adolescents: gender, living location, and age as moderators.

The positive development of the personal belief in a just world (PBJW) plays a vital role in academic achievement and mental health among children and adolescents. Therefore, it is necessary to understand the influencing factors of PBJW better. The association between parenting styles and PBJW has been well established, but whether this association varies among different groups remains an open issue. The present study aimed to examine the strength of the associations between parenting styles and PBJW among Chinese children and adolescents and the role of certain moderators (gender, living location, and age) in these associations. This study employed hierarchical regression and simple slopes analyses to examine data from the National Children's Study of China. The database includes 24,013 Chinese children and adolescents in grades 49 (M = 12.76 years, SD = 1.73), with 53.50% boys. The results indicated that (1) authoritative parenting was positively correlated with PBJW; (2) both authoritarian and permissive parenting styles were negatively correlated with PBJW; (3) the positive relationship between authoritative parenting and PBJW was more prominent in urban regions; the negative relationship between authoritarian and PBJW was stronger in urban regions; and the negative relationship between permissive parenting and PBJW was more pronounced among girls and older children and adolescents. These findings highlight important associations between parenting styles and the development of PBJW among Chinese children and adolescents, and suggest strategies for policy-makers, educators, and parents to improve PBJW for different types of Chinese children and adolescents.

Random field failure and post-failure analyses of vertical slopes in soft clays

This research investigates the spatial heterogeneity of cohesion within soft clay and its implications for slope stability and post-failure analysis. In-situ cone penetration tests were conducted in alluvial soft clays to calibrate probabilistic strength properties. Slope stability analyses employed deterministic, semi-deterministic, and comprehensive probabilistic approaches, while post-failure analysis utilised the nodal integration-based particle finite element method. The undrained shear strength (cu) demonstrated a log-normal distribution (mean: 19 kPa, standard deviation: 3 kPa), with correlation lengths modeled through Bayesian inference. Treating correlation lengths as distributions resulted in a negligible 2% difference compared to using a single value for the probability of failure. Semi-deterministic analyses exhibited results similar to probabilistic analyses, offering computational advantages. Nevertheless, probabilistic analysis, considering spatial variability, provided more comprehensive insights for post-failure analysis. For a vertical slope of critical height in the studied soft clay, probabilistic analyses predicted a range of runout distances from 0 m to over 125 m. Specifically, 89% of these distances were less than 80 m, and 82% were less than 40 m. The findings contribute to an enhanced understanding of spatial variations in soil strength within soft clay slopes, providing valuable insights for future geotechnical assessments and design considerations.

GENDERED PATHWAYS TO FINANCIAL CAPABILITY: IMPLICATIONS FOR PHYSICAL, MENTAL, AND FINANCIAL HEALTH IN LATER LIFE

Abstract Financial capability, comprising financial literacy, access, and behavior, can influence an individual’s ability to effectively use financial resources, thus impacting their health and well-being. However, studies have predominantly focused on financial literacy and overlooked a more comprehensive measure of financial capability. Additionally, there is limited knowledge on the role of gender in these associations. This study investigated how gender may moderate the links between financial capability and health. The study recruited 1,109 community-dwelling adults (aged 45+) through an online survey and employed multivariate linear and logistic regression to examine the gender differences in the associations between financial capability and physical (perceived health and mobility limitations), mental (life satisfaction and depression), and financial (retirement worry and financial satisfaction) health. Results showed that financial access and behavior, compared to financial literacy, had a more significant influence on determining health outcomes. Gender differences in financial capability were also identified through simple slope analyses, with financial literacy being more important for men’s self-rated health and life satisfaction, while financial behavior was more critical for women. Additionally, although financial access was not related to retirement worry among men, it was significantly associated with lower retirement worry among women. Findings suggest that gender-specific pathways to financial capability may lead to health disparities. Policies and programs aimed at improving population’s health and well-being, particularly for women, should target not only financial literacy but also strengthen financial inclusion and encourage responsible financial behavior.