Analysis Of Events Research Articles

A multiparametric heart failure score at baseline is associated with long-term outcome in patients with remotely monitored implantable cardioverter-defibrillators: A pooled analysis of 9 clinical trials

BackgroundTo predict worsening heart failure hospitalizations (WHFHs), the HeartInsight multiparametric algorithm calculates a heart failure (HF) score based on temporal trends of physiologic parameters obtained through automatic daily remote monitoring of implantable cardioverter-defibrillators (ICDs). ObjectiveWe studied the association of the baseline HF score, determined at algorithm activation, with long-term patient outcomes. MethodsData from 9 clinical trials were pooled, including 1841 ICD patients with a preimplantation ejection fraction ≤35%, New York Heart Association class II/III, and no long-standing atrial fibrillation. The primary end point was a composite of death or WHFH. ResultsAfter a median follow-up of 631 days (interquartile range, 385–865 days), there were 243 WHFHs in 173 patients (9.4%) and 122 deaths (6.6%), 52 of which (42.6%) were cardiovascular. The primary end point occurred in 265 patients (14.4%). A multivariable time-to-first-event analysis showed that a high baseline HF score (>23, as determined by a time-dependent receiver operating characteristics curve analysis) was significantly associated with the occurrence of the primary end point (adjusted hazard ratio [HR], 2.05; 95% confidence interval [CI], 1.54–2.71; P < .0001), all-cause death (HR, 2.37; CI, 1.56–3.58; P < .0001), cardiovascular death (HR, 2.19; CI, 1.14–4.22; P = .019), and WHFH (HR, 1.91; CI, 1.35–2.71; P = .0003). In a hierarchical event analysis of all-cause death as the outcome with highest priority and WHFHs as repeated event outcomes, the win ratio was 2.47 (CI, 1.89–3.24; P < .0001). ConclusionBased on a retrospective analysis of clinical trial data with adjudicated events, baseline HF score derived from device-monitored variables was able to stratify patients at higher long-term risk of death or WHFH.

Analysis of adverse events during a cardiac telerehabilitation program: A single-center study.

Analysis of adverse events during a cardiac telerehabilitation program: A single-center study.

Clinical drug interactions between voriconazole and 38 other drugs: a retrospective analysis of adverse events.

Voriconazole (VRZ) is involved in a variety of drug‒drug interactions (DDIs), but few studies have reported adverse events (AEs) associated with the DDIs of VRZ. The primary goal of this study was to analyse the potential risk factors for AEs caused by DDIs between VRZ and other drugs via the OpenVigil FDA platform and to provide a reference for preventing VRZ DDIs and monitoring clinically related adverse drug events. A retrospective pharmacovigilance study was conducted to investigate the AEs related to DDIs between VRZ and four categories of drugs: proton pump inhibitors (PPIs), non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, and other antibacterial drugs. AE information for the target drugs from the first quarter of 2004 to the third quarter of 2022 was downloaded from the OpenVigil FDA data platform. Four frequency statistical models-the reporting ratio method, Ω shrinkage measure model, combination risk ratio model, and the chi-square statistics model-were used to analyse the AEs related to DDIs and evaluate the correlation and influence of sex and age between the drug(s) and the target AEs detected. A total of 38 drugs were included, with 262 AEs detected by at least one of the four models and 48 AEs detected by all four models. Some 77 detected AEs were significantly positively correlated with DDIs and were related to higher reporting rates of AEs than when used alone. Graft-versus-host disease was the AE that had the strongest correlation with the drug interaction between VRZ and immunosuppressants (tacrolimus, mycophenolate mofetil, cyclophosphamide, and cyclosporine), and multiple organ dysfunction syndrome was correlated with VRZ in combination with other antibacterial drugs (linezolid, meropenem, cefepime, and vancomycin). Significant sex and age differences in the target AEs were detected for five and nine target drugs, respectively. For VRZ in combination with linezolid, aggravated conditions and respiratory failure should be given more attention in male patients, and mycophenolate mofetil and respiratory failure in female patients. When conditions are aggravated, febrile neutropenia and septic shock should be of particular concern in patients over 18years of age who use VRZ in combination with ceftazidime, ciprofloxacin, or cytarabine. In patients aged under 18, septic shock should be considered when VRZ is used in combination with meropenem and dexamethasone. AEs related to DDIs should receive more attention when VRZ is used in combination with PPIs (renal impairment), NSAIDs (constipation and renal failure), immunosuppressants (graft versus host disease, septic shock) and other antibacterial drugs (multiple organ dysfunction syndrome, febrile neutropenia, and respiratory failure). Considering the influence of sex and age differences in VRZ DDIs, these factors need to be considered when assessing the risk of AEs in patients receiving VRZ and other drugs.

Social worker as an implementer of solutions introduced by lex Kamilek

The Act of July 28, 2023 amending the Act – Family and Guardianship Code and certain other acts (Journal of Laws 2023, item 1606), in force since February 15, 2024, introduced new solutions aimed at increasing the protection of minors against harm. The changes covered several legal acts and apply to all institutions whose activities are related to the care of children, their education, upbringing, developing their interests or providing them with support. One of the entities performing tasks for a family raising a child is a social worker. Some of the legal solutions introduced by so called lex Kamilek are reflected in his daily work. First of all, as part of the procedure for ensuring protection for a child in the event of a threat to his life or health in connection with domestic violence, a social worker will be obliged, together with a police officer and a doctor, paramedic or nurse, to complete a questionnaire assessing the risk of threat to the child's life or health. Moreover, in the case of employment in institutions dealing with child care, the person must be verified in terms of information from the Register with limited access or in the Register of persons in relation to whom the State Commission for Counteracting the Sexual Exploitation of Minors under 15 years of age has issued a decision on entry in the Register and the National Criminal Register. It is also obliged to implement standards for the protection of minors.As an employee of a specific institution, he or she may be obliged to provide the Team of Experts for the Analysis of Events as a result of which a minor died or suffered serious bodily injury, certain information and documents without the obligation to maintain professional secrecy.

The investigation of diving accidents and fatalities.

Diving accidents result from a variety of causes including human error, inadequate health and fitness, environmental hazards and equipment problems. They usually involve a cascade of events resulting in the diver being injured or deceased. The accuracy and usefulness of a diving accident investigation relies on well-targeted interviews, good field investigation, evidence collection and preservation, and appropriate equipment assessment. In the event of a fatality, a thorough and targeted autopsy is indicated. Investigators should have the appropriate knowledge, training, skills and support systems to perform the required tasks. Relevant investigations include the victim's medical and diving history, the dive circumstances and likely accident scenario, management of the accident including rescue and first aid, equipment inspection and testing and a thorough postmortem examination conducted by a forensic pathologist with an awareness of the special requirements of a diving autopsy and the knowledge to correctly interpret the findings. A chain of events analysis can determine the likely accident scenario, identify shortcomings and inform countermeasures.

Cardiovascular and fracture events analysis and intervention strategies in patients undergoing parathyroidectomy with secondary hyperparathyroidism.

Chronic kidney disease (CKD), especially end-stage renal disease (ESRD), is the most common cause of secondary hyperparathyroidism (SHPT), and SHPT is the most severe complication of ESRD. This study aimed to analyze the influencing factors of cardiovascular and fracture events in patients with SHPT which are the leading causes of death in patients with CKD, and provide a reference for selecting patients for whom surgery is more suitable. Patients who underwent parathyroidectomy (PTX) for SHPT at The First Affiliated Hospital, Zhejiang University School of Medicine from September 2021 to April 2024 were selected as the study object, with the inclusion and exclusion criteria as followed. They were divided into rural and urban residents for comparison as a cross-sectional study. The study evaluated the comorbidities, socioeconomic status, and postoperative complications diagnosed by radiography of patients undergoing surgery for SHPT. A total of 119 patients were included, among whom, 71 were from rural areas and 48 were from urban areas. Compared with urban residents, rural residents had poorer economic conditions, a longer interval from disease onset to PTX, and a higher incidence of cardiovascular and fracture events and concurrent nephrolithiasis, all of which were statistically significant. Multivariate analysis indicated that place of residence, age, and duration of uremia were independent risk factors of cardiovascular/fracture events. Medical staff in ESRD outpatient clinics should pay attention to patients with SHPT. ESRD patients should have better surveillance especially for rural, elder and poor phosphorus control patients, and promptly assess surgical intervention measures.

Условия появления интенсивных потоков энергичных электронов на L&lt;1.2, связанные с солнечной активностью и параметрами солнечного ветра

We present the results of a statistical study of transient enhancements of electrons with energies &gt;30 keV at low drift shells in the quasi-trapped region (forbidden zone) at the geomagnetic equator. Using data from low-altitude NOAA/POES and MetOp satellites, we have compiled a catalog of events with forbidden energetic electron (FEE) enhancements for the period from 1998 to 2023. Statistical analysis of FEE events has revealed solar-cyclic, as well as seasonal and diurnal variations in the occurrence of FEE enhancements. We have examined the correlation of the annual frequency of FEE events with solar activity, solar wind parameters, and geomagnetic activity. Strong correlations have been found with the F10.7 index of solar activity (radio emission flux) as well as with the Alfvén Mach number (solar wind parameter). An interpretation of the obtained results is proposed which is based on the mechanism of electrical drift and radial transport of electrons from Earth’s inner radiation belt to the quasi-trapped region (L&lt;1.2). The key factor for the operation of the mechanism is the effective penetration of the electric field to low latitudes when a significant difference in the conductivity of the high-latitude ionosphere occurs in the illuminated and unilluminated sectors of local time under conditions of weakening auroral activity.

Conditions for the occurrence of intense fluxes of energetic electrons at L&lt;1.2 associated with solar activity and solar wind parameters

We present the results of a statistical study of transient enhancements of electrons with energies &gt;30 keV at low drift shells in the quasi-trapped region (forbidden zone) at the geomagnetic equator. Using data from low-altitude NOAA/POES and MetOp satellites, we have compiled a catalog of events with forbidden energetic electron (FEE) enhancements for the period from 1998 to 2023. Statistical analysis of FEE events has revealed solar-cyclic, as well as seasonal and diurnal variations in the occurrence of FEE enhancements. We have examined the correlation of the annual frequency of FEE events with solar activity, solar wind parameters, and geomagnetic activity. Strong correlations have been found with the F10.7 index of solar activity (radio emission flux) as well as with the Alfvén Mach number (solar wind parameter). An interpretation of the obtained results is proposed which is based on the mechanism of electrical drift and radial transport of electrons from Earth’s inner radiation belt to the quasi-trapped region (L&lt;1.2). The key factor for the operation of the mechanism is the effective penetration of the electric field to low latitudes when a significant difference in the conductivity of the high-latitude ionosphere occurs in the illuminated and unilluminated sectors of local time under conditions of weakening auroral activity.

Dynamics of rain-triggered lahars and destructive power inferred from seismo-acoustic arrays and time-lapse camera correlation at Volcán de Fuego, Guatemala

AbstractLahars, or volcanic mudflows, are one of the most devastating natural, volcanic hazards. Deadly lahars, such as the one that occurred after the Nevado del Ruiz, Columbia eruption in 1985, in which at least 23,000 people tragically lost their lives, threaten the safety and well-being of humans, the economy, and the infrastructure of many of the communities living in the vicinity of volcanoes. Due to their complex flow behaviors, lahars remain a major challenge to those studying them. We present an analysis of several rain-triggered lahar events at Volcán Fuego in Guatemala using both seismic and infrasound monitoring to quantify both ground vibrations and low-frequency atmospheric sound waves associated with these mudflows. Geophysical data collected over this field campaign quantifies flow parameters such as velocities, stage and the frequency of these rain-triggered lahars. Time-lapse imagery of lahar flows is compared with filtered seismo-acoustic signal characteristics to ascertain stage predictions and relationship to stage fluxes. Using random forest regression models, we establish moderate correlations (correlation coefficient modes 0.48–0.53) with statistical significance (p value = 0.01–0.02) between signal energetics and respective stage. Compiling a catalog of rain-triggered lahar events in Volcán de Fuego’s drainages over a season permits a dataset amenable to statistical analysis. Our goal is the development of new-generation geophysical monitoring tools that will be capable of remote and real-time estimation of flow parameters.

SemConvTree: Semantic Convolutional Quadtrees for Multi-Scale Event Detection in Smart City

The digital world is increasingly permeating our reality, creating a significant reflection of the processes and activities occurring in smart cities. Such activities include well-known urban events, celebrations, and those with a very local character. These widespread events have a significant influence on shaping the spirit and atmosphere of urban environments. This work presents SemConvTree, an enhanced semantic version of the ConvTree algorithm. It incorporates the semantic component of data through semi-supervised learning of a topic modeling ensemble, which consists of improved models: BERTopic, TSB-ARTM, and SBert-Zero-Shot. We also present an improved event search algorithm based on both statistical evaluations and semantic analysis of posts. This algorithm allows for fine-tuning the mechanism of discovering the required entities with the specified particularity (such as a particular topic). Experimental studies were conducted within the area of New York City. They showed an improvement in the detection of posts devoted to events (about 40% higher f1-score) due to the accurate handling of events of different scales. These results suggest the long-term potential for creating a semantic platform for the analysis and monitoring of urban events in the future.

The impact of e-sports championships on stock prices of sponsoring companies

This paper studies the impact of esports matches results on the dynamics of sponsoring companies shares. Statistics on three main esports leagues is reviewed: Defense of the Ancient 2, League of legends and Counter Strike: Global Offensive, with Samsung, MegaFon, Intel, HTC corporation, MSI, Asus, Comcast Xfinity, Logitech, Lenovo, BMW, Honda, AMD and a number of several lesser-known companies as sponsors. The study will test the assumption concerning the growth of share prices of the companies sponsoring esports events. Another purpose of the study is to identify the most profitable esports teams and championships. The work will also include an event analysis designed to answer the question of which leagues for which sponsor companies may be preferable in terms of return on investment and why. In particular, the event window will be considered in the context of the teams in middle places, as well as in the context of the winners and losers in a particular esports league. In addition, all sponsors will be divided into their production areas to track the impact of the industry factor. The main result is that the profitability of companies associated with the video game industry will have low correlation with the outcomes of matches of esports teams. The findings show that if a team has the least number of sponsors, there is a greater return on shares than for other teams with a greater number of sponsors.

Genetic and Evolutionary Analysis of Canine Coronavirus in Guangxi Province, China, for 2021-2024.

Canine coronavirus (CCoV) is an important gastrointestinal pathogen that causes serious harm to pet dogs worldwide. Here, 1791 clinical samples were collected from pet dogs in different pet hospitals in Guangxi Province, southern China, for the 2021-2024 period and detected for CCoV by a multiplex RT-qPCR. The results showed that 8.43% (151/1791) of samples were positive for CCoV. Sixty-five positive samples were selected to amplify, sequence, and analyze S, M, and N genes. A sequence comparison revealed that the nucleotide and amino acid similarities of the S, M, and N genes were 94.86% and 94.62%, 96.85% and 97.80%, and 96.85% and 97.80%, respectively. Phylogenetic analysis indicated that 65 CCoV strains obtained in this study belonged to the CCoV-II genotype, of which 56 CCoV strains belonged to the CCoV-IIa subtype and 9 CCoV strains belonged to the CCoV-IIb subtype. A potential recombination event analysis of S gene sequences indicated that two CCoV strains, i.e., GXBSHM0328-34 and GXYLAC0318-35, have recombination signals. A Bayesian analysis indicated that the evolutionary rates of the S, M, and N genes were 1.791 × 10-3, 6.529 × 10-4, and 4.775 × 10-4 substitutions/site/year, respectively. The population size grew slowly before 1980 and then began to shrink slowly; it then shrank rapidly in 2005 and expanded sharply in 2020, leveling off thereafter. These results indicated the CCoV strains prevalent in Guangxi Province, southern China, showed a high level of genetic diversity and maintained continuous variation among clinical epidemic strains.

Lenvatinib Plus Pembrolizumab versus Doxorubicin for Advanced or Recurrent Endometrial Cancer with Short Treatment-Free Intervals Following First-Line Carboplatin Plus Paclitaxel

Background: The treatment-free interval is a significant predictor of worse prognosis and poor response rates of the second-line treatment in patients with carboplatin and paclitaxel (PT)-pretreated, advanced, or recurrent endometrial cancer (EC). Whether lenvatinib plus pembrolizumab still confers a survival benefit compared with doxorubicin in patients with platinum-free intervals of &lt;6 months remains unclear. Methods: This multi-institutional retrospective analysis was performed using de-identified electronic health records from the TriNetX Research Network. Patients with advanced or recurrent ECs who received lenvatinib plus pembrolizumab or doxorubicin within six months of first-line PT were identified. A 1:1 propensity score matching (PSM) was conducted to control for potential confounding variables. Overall survival (OS) and adverse event profile were the primary and secondary outcomes. Results: Between January 2018 and February 2024, 130 patients with PT-treated, advanced, or recurrent ECs who received lenvatinib plus pembrolizumab and 122 patients who received doxorubicin at a platinum-free interval of &lt;6 months were identified across 31 healthcare organizations. In the balanced cohort following PSM with 117 patients in each group, treatment with lenvatinib plus pembrolizumab was associated with improved OS compared with treatment with doxorubicin (12.8 vs. 8.2 months, p = 0.012, hazard ratio: 0.65, 95% confidence interval: 0.46–0.91). Regarding adverse event analysis, a higher incidence of hypothyroidism and proteinuria was observed with lenvatinib plus pembrolizumab, and more hematological toxicities were observed with doxorubicin. Conclusions: in patients with treatment-free intervals of &lt;6 months, lenvatinib plus pembrolizumab still confers improved survival compared with doxorubicin in PT-treated, advanced, or recurrent ECs.

Adhesion Mechanics and Detachment Dynamics of Vanishing Surface Layers on Hydrogels.

Cross-linked hydrogel surfaces exhibit reduced stiffness when polymerized against polymeric hydrophobic surfaces. As such, these layers play a critical role in contact mechanics, particularly exhibiting strong relative adhesion with colloidal probes when the contact area is small. This prevents the use of continuum models of adhesive soft contact. To connect mechanisms of stretch to the force response, depth-controlled nanoindentation experiments were conducted on polyacrylamide (pAAM) hydrogel samples using colloidal probe atomic force microscopy (AFM). The pAAM sample had a high water content of >90% and was molded against polyoxymethylene (POM) to create a more dilute surface layer with thickness ∼0.5 μm. Indentations to multiple depths between 50 nm and 1.25 μm were repeated 10 times each. First, the force drops during the unloading, and separation segments of each indentation were characterized. This described the detachment progression for increasing areas of contact, revealing that the pull-off force for a single chain was in the single-pN range. Second, the stretched polymer network was modeled as an array of parallel, linear springs. Assuming a constant areal chain density of α = 100 chains/μm2, the maximum force of adhesion was plotted versus the volume of chains stretched upward, and the average chain stiffness was calculated from a linear fit to be 22.8 × 10-6 N/m. A Weibull distribution analysis of detachment events revealed a dependence of chain stiffness on maximum indentation depth (dmax), with higher stiffness at shallower depths approaching kchain ≈ 20 × 10-6 N/m. These findings on adhesion mechanics between a vanishing hydrogel surface and probe can guide the development of multifunctional hydrogels for various biomedical applications.

Social Role of the Tradition of Protest Song Tradition of Popular Music mid-20th century in the United States

Introduction. The article considers the integrating social role of the tradition of protest songs in the period 1950–1970 on the example of the United States of America. This period was characterized by a series of military conflicts against the background of geopolitical confrontation between the USSR and the USA, which was reflected in creative and sociocultural movements for peace and contributed to social and political changes in the USA. Protest music not only contributed to a positive influence on political decision-making, but also became a powerful means of expressing public opinion and feelings.Methodology and sources. The methodology and theory is based on comparative historical analysis of socio-cultural, political and historical events and facts related to the period covered. The material for the study was also made up of biographies, descriptions of events by eyewitnesses and documents of secondary analysis, telling about the social and musical impact of the phenomenon of protest songs of folk music and rock'n'roll counterculture on American society, as a reaction to the political decisions of the U.S. government to create hotbeds of military conflicts in the world.Results and discussion. The period from the late 1940s to the 1950s in the United States was marked by an acute confrontation between communism and capitalism, which was reflected in the culture and music of the time. The emergence and proliferation of protest songs, as well as other forms in the arts, occurs because of important crisis events on a global scale, or when people begin to see these events as such. Because of the impact the conflict between the two superpowers and their allies had on the world, people began to react to it in their own way. Music reacted to the events instantly and vividly. Although most protest songs were not a national success and their message was mostly appreciated by radicals, the songs united people and helped them express their discontent with what was happening.Conclusion. Folk and rock music became an integral part of life during the Cold War within the United States. Musicians and poets protested against the administration's policies, against unnecessary military conflicts, and warned against the possible destruction of the world. As a result, these genres became a powerful means of expressing public feelings, opinions, and influenced the formation of public consciousness right up to our time.

Comparative safety analysis of lacosamide and perampanel in epilepsy management: insights from FAERS database.

Epilepsy is a chronic neurological condition requiring effective management with minimal adverse effects. Lacosamide (LCM) and Perampanel (PER), two promising treatments, have distinct profiles that merit comparative analysis to guide clinical decision-making. This study utilizes a pharmacovigilance analysis of adverse events reported in the FDA Adverse Event Reporting System database from Q1 2009 to Q3 2023. Employing disproportionality and Bayesian analyses, we assessed and compared the AE signals associated with LCM and PER to elucidate their safety profiles in epilepsy treatment. The analysis included 12,576 AE reports for LCM and 2,703 for PER, highlighting a higher incidence of psychiatric disorders, including aggression with LCM, and a notable association of PER with psychiatric disorders such as psychotic disorders and dizziness. LCM showed a relatively safe profile during pregnancy, whereas PER's data suggested caution due to reported cases of suicidal ideation and attempts. This comprehensive evaluation underscores the importance of understanding the distinct AE profiles of LCM and PER in clinical practice, providing valuable insights for personalized epilepsy management. Future research with rigorous prospective designs is recommended to validate these findings and explore the mechanisms underlying the reported adverse events.

Geotechnical analysis and stability assessment of a landslide event in Gera Woreda, Ethiopia

Geotechnical analysis and stability assessment of a landslide event in Gera Woreda, Ethiopia

Clozapine, relapse, and adverse events: a 10-year electronic cohort study in Canada.

Clozapine is the most effective medication for treatment-resistant psychoses, but the balance of benefits and risks is understudied in real-world settings. To examine the relative re-hospitalisation rates for mental health relapse and adverse events associated with clozapine and other antipsychotics in adult and child/youth cohorts. Data were obtained from the Canadian Institute of Health Information for adults (n = 45 616) and children/youth (n = 1476) initially hospitalised for mental health conditions in British Columbia, Manitoba and Saskatchewan from 2008 to 2018. Patient demographics and hospitalisations were linked with antipsychotic prescriptions dispensed following the initial visit. Recurrent events survival analysis for relapse and adverse events were created and compared between clozapine and other antipsychotics. In adults, clozapine was associated with a 14% lower relapse rate versus other drugs (adjusted hazard ratio: 0.86, 95% CI: 0.83-0.90) over the 10-year follow-up. In the first 21 months, the relapse rate was higher for clozapine but then reversed. Over 1000 person-months, clozapine-treated adults could be expected to have 38 relapse hospitalisations compared with 45 for other drugs. In children/youth, clozapine had a 38% lower relapse rate compared with other antipsychotic medications (adjusted hazard ratio: 0.62, 95% CI: 0.49-0.78) over the follow-up period. This equates to 29 hospitalisations for clozapine and 48 for other drugs over 1000 person-months. In adults, clozapine had a higher risk for adverse events (hazard ratio: 1.34, 95% CI: 1.18-1.54) over the entire follow-up compared with other antipsychotics. This equates to 1.77 and 1.30 hospitalisations over 1000 person-months for clozapine and other drugs, respectively. Clozapine was associated with lower relapse overall, but this was accompanied by higher adverse events for adults. For children/youth, clozapine was associated with lower relapse all throughout and had no difference in adverse events compared with other antipsychotics.

Annealing Temporal–Spatial Contrastive Learning for multi-view Online Action Detection

In open-world scenarios, the analysis of action events from multiple viewpoints is crucial for achieving a holistic understanding, a concept that resonates with human perception. However, achieving a synthesis of information from multiple viewpoints presents a challenge, as the data can induce inter-view regularization, complicating the learning process. This paper is the first to delve into Online Action Detection (OAD) through a multi-view lens, underscoring the value of cross-observation in enriching view-level information. By harnessing the spatiotemporal dynamics inherent in multi-view video sequences, an Annealing Temporal–Spatial Contrastive Learning (ATSCL) consisting of Annealing Temporal Contrastive Learning (ATCL) and Spatial Contrastive Learning (SCL) is proposed, optimized for compatibility with RNN-based models. ATCL employs an annealing temporal loss to uncover the intrinsic video structures via a temporal annealing sampling mechanism. Concurrently, SCL utilizes a spatial loss to draw representations from various viewpoints closer together, mitigating the regularization effects. The ATSCL liberates training multi-view OAD from the stringent requirements of synchronized training videos, enabling the execution of OAD tasks asynchronously. Experiments demonstrate that the RNN-based models realize an average improvement of 5.92% on the DAHLIA dataset, 3.36% on the IKEA ASM dataset, 2.92% on the BREAKFAST dataset and 0.6% (mAP) on the THUMOS’14 dataset following the integration of the ATSCL framework, underscoring the ATSCL’s efficacy across different RNN structures.

РАГУИЛ ДОБРЫНИЧ КАК ИСТОРИЧЕСКАЯ ЛИЧНОСТЬ

The article presents a historical reconstruction of the biography of one of the most prominent historical figures of Ancient Rus’ of the 12th century. – Novgorod boyar Raguil Dobrynich. During the research process, special methods of cognition were used (historical-analytical and problem-chronological). The materials that form the basis of the study were studied and analyzed taking into account the chronology of events and the need to obtain historical information from the scientific sources being studied. When comparing different theoretical views on the analyzed problems, the method of comparative and retrospective analysis was used.The authors conducted a historiographic analysis of the problem posed in the study and identified the main sources used in writing the article. Based on the texts of ancient Russian chronicles, as well as the contents of birch bark letter No. 831, the authors reconstructed the Novgorod period of the biography of Raguil Dobrynich, and also outlined his role in the historical events associated with the expulsion and murder of Prince Igor Olegovich.Particular attention in the article is paid to the analysis of the historical events of 1170 related to the revolt of the Novgorod squad against their prince Vladimir Mstislavich, in which Raguil Dobrynich played a key role.