Amplitude Of Postural Tremor Research Articles

Treatment of essential tremor with arotinolol

We investigated the effect of arotinolol, a new peripherally acting beta-adrenergic blocker, in 15 patients with essential tremor. The patients received 30 mg per day of arotinolol for 8 weeks. Accelerometer readings showed a significant reduction in amplitude of postural tremor after treatment. Action tremor also improved to essentially the same degree as postural tremor. The present findings support the view that the therapeutic effect of beta-blockers in essential tremor is mediated by peripheral beta-adrenergic receptors.

Physiological characteristics of tremor after chronic lithium therapy.

Twenty-three patients taking lithium carbonate alone in therapeutic dosage for a mean period of 43 months (range 6--108 months) and 23 control subjects matched for age and sex had the frequency and amplitude of postural tremor measured and extrapyramidal symptoms assessed by standard techniques. Patients on lithium had a significantly lower peak frequency of tremor than control subjects (P less than 0.05) and significantly greater extrapyramidal symptoms (P less than 0.01), indicating that tremor appearing after chronic lithium therapy is likely to be an extrapyramidal symptom. Such symptoms are common long-term adverse effects of lithium carbonate.

Tremor and somatosensory studies during chamber He-O2 compressions to 13.1, 25.2, 37.3, and 49.4 ATA

Comparison was made between intentional and postural tremor amplitudes with a 2-to 50-Hz bandwidth in four men rapidly compressed from surface to 13.1, 25.2, and 37.3 ATA in 4 h while breathing helium-oxygen mixtures (Predictive Studies IV, University of Pennsylvania). Excursions with compression rates of 20 and 40 ft/min were then made to 49.4 ATA on exposure days 2 and 3, returning to saturation at 37.3 ATA for 6 additional days. During compression from 25.2 to 37.3 ATA, there were increases in tremor amplitudes for both intentional and postural tremor in the 3-to 7-Hz and 8- to 12-Hz ranges. Both types of tremor showed increases in amplitudes at 49.4 ATA on exposure days 2 and 3. Amplitude changes in postural tremor, which occurred only on the fastest compression to 49.4 ATA, were less evident than those in intentional tremor during the remaining dive profile, and adaptation to pressure exposure could be defined by day 8. Intentional tremors did not show adaptation at pressure.