Amount Of Peroxide Research Articles

Metallic Copper-Based Dual-Enzyme Biomimetic Nanoplatform for Mild Photothermal Enhancement of Anticancer Catalytic Activity.

Background: Chemodynamic therapy (CDT) is recognized as a promising cancer treatment. Recently, copper sulfide nanostructures have been extensively employed as Fenton-like reagents that catalyze the formation of acutely toxic hydroxyl radicals (·OH) from hydrogen peroxide (H2O2). However, CDT therapeutic potency is restricted by the tumor microenvironment (TME), such as insufficient amounts of hydrogen peroxide, excessive glutathione levels, etc. To address these disadvantages, glucose oxidase (GOx) or catalase (CAT) can be utilized to enhance CDT, while low therapeutic efficacy still inhibits their future applications. Our previous study revealed that mild photothermal effect could boost the CDT catalytic effectiveness as well as GOx enzyme activity over a range. Results: We engineered and constructed a hollow CuS nanoplatform loaded with GOx and CAT, coating with macrophage membranes (M@GOx-CAT@CuS NPs). The nanoplatforms allowed enhancement of the reactive oxygen species creation rate and GOx catalytic activeness of CDT through mild phototherapy directed by photoacoustic imaging. After actively targeting vascular cell adhesion molecule-1 (VCAM-1) in cancer cells mediated by macrophage membrane coating, M@GOx-CAT@CuS NPs released GOx and CAT under near-infrared irradiation. GOx catalyzed the formation of H2O2 and gluconic acid with glucose, creating a better catalytic environment for CDT. Meanwhile, CAT-catalyzed H2O2 decomposition to generate sufficient oxygen, appropriately alleviating the oxygen shortage in the TME. In addition, starvation effects decreased adenosine triphosphate levels and further underregulated heat shock protein expression to reduce the heat resistance of tumor cells, resulting in a better mild phototherapy outcome. Both invitro and invivo experiments demonstrated that the newly developed M@GOx-CAT@CuS nanoplatform has remarkable synergistic anticancer therapeutic effects. Conclusion: The cascade reaction-enhanced biomimetic nanoplatform opens up a new avenue for precision tumor diagnostic and therapeutic research.

H2O2/acid self-supplying double-layer electrospun nanofibers based on ZnO2 and Fe3O4 nanoparticles for efficient catalytic therapy of wound infection.

Catalytic therapy based on nanozymes is promising for the treatment of bacterial infections. However, its therapeutic efficacy is usually restricted by the limited amount of hydrogen peroxide and the weak acidic environment in infected tissues. To solve these issues, we prepared polyvinyl alcohol (PVA)-polyacrylic acid (PAA)-iron oxide (Fe3O4)/polyvinyl alcohol (PVA)-zinc peroxide (ZnO2) double-layer electrospun nanofibers (PPF/PZ NFs). In this design, PVA serves as the carrier for ZnO2 nanoparticles (NPs), Fe3O4 NPs, and PAA. The double-layer structure of nanofibers can spatially separate the PAA and ZnO2 to avoid their reaction with each other during preparation and storage, while in the wet wound bed, PVA can dissolve and PAA can provide H+ ions to promote the generation of hydrogen peroxide and subsequent conversion to hydroxyl radicals for bacteria killing. In vitro experimental results demonstrated that PPF/PZ NFs can reduce the methicillin-resistant Staphylococcus aureus by 3.1 log (99.92%). Moreover, PPF/PZ NFs can efficiently treat the bacterial infection in a mouse wound model and promote wound healing with negligible toxicity to animals, indicating their potential use as "plug-and-play" antibacterial wound dressings. This work provides a novel strategy for the construction of double-layer electrospun nanofibers as catalytic wound dressings with hydrogen peroxide/acid self-supplying properties for the efficient treatment of bacterial infections.

Significant effects of negligible amount of H2O2 on photocatalytic efficiency of MIL-125 and NH2-MIL-125 nanostructures in degradation of methylene blue.

The notable impact of a trace amount of hydrogen peroxide (H2O2) on the photocatalytic performance of Ti-based metal-organic frameworks (MOFs), namely MIL-125 and NH2-MIL-125, in the purification of water polluted with chemical agents was studied experimentally. MIL-125 and NH2-MIL-125 were synthesized using the solvothermal method and were characterized by a variety of diagnostic methods. NH2-MIL-125 exhibited a bandgap of 2.8 eV compared to 3.65 eV for MIL-125 with optimal visible light capture capability, indicating the outstanding photodegradation activity of the synthesized MOFs. In addition, the photocatalytic performance of MIL-125 and NH2-MIL-125 was tested for the degradation of methylene blue (MB) as a chemical pollutant in water under both dark conditions and irradiation by visible light and a UVC lamp. NH2-MIL-125 exhibited a significantly higher photodegradation rate compared to MIL-125 due to the presence of the amino group, higher surface electronegativity and slightly lower bandgap. Furthermore, the effect of H2O2 as an electron acceptor on the efficiency of MB degradation was investigated, which markedly enhanced the photocatalytic MB degradation performance due to the ligand-to-metal charge transfer mechanism, particularly for NH2-MIL-125, under all tested conditions.

Impact of salicylic acid and sodium hydrosulfide applied singly or in combination on drought tolerance and grain yield in wheat plants

AbstractClimate change‐induced drought stress (DS) poses a significant threat to crop production, emphasizing the need for innovative strategies to mitigate its adverse effects. Prior studies have demonstrated the distinct capacities of salicylic acid (SA) and sodium hydrosulfide (NaHS) to augment plant resilience against drought‐related stressors. However, little is known about how they work together or the specific processes by which they increase DS tolerance. The purpose of this research was to determine how SA and NaHS affected the performance of wheat plants during the growing seasons of 2021–2022 and 2022–2023, when there was a drought. The research employed a block‐randomized experimental layout with split plots, where the primary factors included two irrigation levels: full irrigation (IW1, 100% of water requirement) and deficit irrigation (IW2, 50% of water requirement). Secondary factors included the application of mock control, 0.5 mM SA, and 0.3 mM NaHS, an H2S donor, either individually or in combination, administered before the onset of DS. The application of SA, NaHS, or their combination significantly enhanced wheat plant resistance to DS. Significant increases in a number of physiological markers, including proline content, relative water content (RWC), Fv/Fm, chlorophyll content, and antioxidant enzyme activity, demonstrated this improvement. Furthermore, in drought‐stressed wheat plants, SA and NaHS treatments decreased the amounts of hydrogen peroxide (H2O2), malondialdehyde (MDA) content, and electrolyte leakage (EL). In conclusion, our study highlights the possibility of SA and NaHS, whether applied individually or in combination, to improve drought resistance in wheat plants, presenting a viable approach to lessen the effects of climate change on agricultural yield.

The Systematic Assessment of the Membrane-Stabilizing and Antioxidant Activities of Several Kazakhstani Plants in the Asteraceae Family.

The objective of our research was to examine the antioxidant and membrane-protective characteristics of a few medicinal plant extracts belonging to the Asteracea family, along with their flavonoid and polyphenolic content, in order to identify strategies for enhancing beverage composition and boosting the antioxidant capacity of green and black tea. The activity of aqueous-ethanolic extracts from the dried parts of plants, such as Arictum tomentosum Mill., Ghnapilum kasachstanicum Kirp. & Kuprian. ex Kirp., Artemisia schrenkiana Ledeb., A. rutifolia Steph. ex Spreng., A. cina O.Berg, and A. vulgaris L., were examined using a model of Wistar rats. Thiobarbituric acid-reacting substances (TBARS), a marker of malondialdehyde concentration, were used to measure the amount of lipid peroxidation (LPO) in liver microsomes. Considering the outcomes, the extracts from A. tomentosum, G. kasachstanicum, and A. vulgaris exhibit the strongest membrane-stabilizing action among those examined. At a concentration of 5 g/mL, the extracts of these plants demonstrated a significant anti-hemolitic impact, whereas the remaining extracts displayed a similar effect at doses above 10 g/mL. Accordingly, among the extracts studied, the A. tomentosum, G. kasachstanicum, A. schrenkiana, A. rutifolia, A. cina, and A. vulgaris extracts have significant antioxidant properties. The integrated antioxidant and antihemolytic qualities of A. tomentosum and green tea extracts were comparable to those of the individual plant extracts. When the extracts of A. schrenkiana and green tea were combined, similar outcomes were seen, suggesting that there was no appreciable synergistic interaction.

Modulation of growth and chemical element accumulation in <i>Fragaria × ananassa</i> plants <i>in vivo</i> under the effect of silicon chelates

Due to the protective role played by silicon in plants against unfavorable environmental conditions, siliconcontaining preparations are of considerable interest as biostimulants. In this work, a mechanical composite of rice husk and green tea containing soluble silica chelate complexes was used as the source of silicon. The study aims to examine the effect of silicon chelates on the growth and physiological parameters and the chemical composition of Fragaria × ananassa plants (Solnechnaya Polyanka variety) under greenhouse conditions. The plants were watered using water without a mechanical composite (control) or an aqueous solution containing 0.3 g/L of mechanical composite twice per period. Sampling was carried out one week after the last treatment. In order to determine the concentration of chemical elements (Si, P, S, Cl, K, Ca, Ti, Mn, Fe, Ni, Cu, Zn, Br, Rb, Sr, and Mo) in the roots and shoots of garden strawberry, it was proposed to use synchrotron X-ray fluorescence analysis. The use of the mechanical composite was shown to increase the amount of chlorophyll a, chlorophylls a and b, and carotenoids; decrease the amount of hydrogen peroxide; and increase the activity of the main antioxidant enzymes (superoxide dismutase, catalase, and peroxidase). It was determined that under the effect of the preparation, silicon accumulates primarily in shoots, affecting the accumulation of micro- and macroelements in the shoots and roots of plants. The obtained results substantiate the use of silicon-containing “green chemistry” as a means of controlling the growth and development of garden strawberry plants under in vivo conditions.

Cell structure damage contributes to antifungal activity of sodium propylparaben against Trichothecium roseum

Trichothecium roseum is a type of fungus that causes pink rot in muskmelon after the melons are harvested. Pink rot leads to severe decay during storage and causes the production of toxins that can be harmful to human health. Sodium propylparaben (SPP, IUPAC name: sodium; 4-propoxycarbonylphenolate) is an antimicrobial preservative that can be used to treat the inedible parts of fruits in addition to food, medications, and packaging. In this study, the effectiveness of SPP in inhibiting T. roseum was tested, and the inhibition mechanism was investigated. The results show that SPP inhibited the growth and spore germination of T. roseum. The malondialdehyde (MDA) content, propidium iodide staining, alkaline phosphatase (AKP) activity, and calcofluor white (CFW) staining results show that SPP produced a disruption of the cell membrane and cell wall integrity of T. roseum. Scanning and transmission electron microscopy (SEM and TEM, respectively) results also indicate that SPP disrupted the cellular structure of T. roseum. Meanwhile, the large amounts of superoxide anion and hydrogen peroxide in T. roseum accumulated due to the effects of SPP on the activities of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, superoxide dismutase, and decreased catalase. In addition, SPP caused a significant reduction in the incidence rate and disease degree of muskmelon pink rot in vivo. In conclusion, SPP appears to be effective against T. roseum via disruption of the cell membrane and wall. SPP could be used to manage melon pink rot after fruit harvesting because of its disease inhibition effect in vivo.

Effects of Peroxide and Sulfur Curing Systems on Physical and Mechanical Properties of Nitrile Rubber Composites: A Comparative Study.

This study compares the effect of sulfur and dicumyl peroxide (DCP) vulcanizing systems on the physical and mechanical properties of rubber compounds based on acrylonitrile butadiene rubber (NBR). NBR compounds cured by different amounts of DCP and NBR vulcanizates filled with various concentrations of carbon black (CB) and a constant amount of sulfur or DCP were prepared. The vulcanizates were characterized by tensile testing, dynamic mechanical thermal analysis (DMTA), and cross-link density determination. The tensile strength and Young's modulus were found to increase with the rising amount of DCP and CB, while elongation at break decreased. The samples vulcanized by the sulfur system and filled with CB show a substantial increase in tensile strength from 13.1 to 21.2 MPa. Higher storage modulus and glass transition temperature were observed with the increase in the amount of peroxide and filler, and consequently, the increase in cross-link density, indicating rigidity increase and lower molecular mobility. The changes in the physical and mechanical properties of the NBR vulcanizates were in correlation with the changes in solvent uptake and cross-link density.

Comparative Study of Organics Removal from Refinery Wastewater by Photocatalytic Fenton Reaction Coupled with Visible Light and Ultraviolet Irradiation

The study investigates photocatalytic advanced oxidation processes using iron-doped zeolite catalysts in heterogeneous Fenton reactions to degrade organic contents as chemical oxygen demand. The research revealed that the heterogenous photocatalytic Fenton process was the most successful treatment method under acidic circumstances and generated a greater rate of chemical oxygen demand degradation in a concise amount of radiation time. Compared to the heterogenous Fenton process with ultraviolet irradiation, it increased oxidation and was affected by catalyst load, power of hydrogen pH, hydrogen peroxide amounts, and temperature. The findings showed that the iron-doped zeolite catalyst, pH, and temperature significantly degraded the chemical oxygen demand. The experiment determined that the optimal conditions were obtained at a catalyst load of 0.07 g, pH of 3, with 20% excess of hydrogen peroxide, 40 °C in 2 hours for the ultraviolet/ iron-doped zeolite/hydrogen peroxide system that gave 99.84 % of the removal of the chemical oxygen demand. The heterogeneous photocatalytic Fenton method accompanied the reactions by hydroxyl radical production, which quickly reached its maximal reduction.

Response of the antioxidant system of wheat seedlings with different genotypes to exogenous prooxidants: the relationship with resistance to abiotic stressors

Oxidative stress is an important component of heat- and drought-induced damage in plants. However­, information on the relationship between the resistance of cultivated plants with different genotypes to environmental factors and their ability to maintain a pro-/antioxidant balance remains contradictory. This study aimed to compare the growth responses and adaptation ability of the antioxidant system in different wheat cultivars to oxidative stress agents hydrogen peroxide and iron(II) sulfate. Etiolated seedlings of common winter wheat (Triticum aestivum L.) Antonivka and Tobak (heat- and drought-tolerant), and Avgustina and Doskonala (not resistant to heat and drought) were used for the study. Three-day-old etiolated seedlings were exposed to 50 mM H2O2 or 5 mM FeSO4 for one day. It was found that seedlings of Antonivka and Tobak cultivars treated with H2O2 or FeSO4 were able to maintain relatively intensive growth, accumulated significantly lower amounts of endogenous hydrogen peroxide and lipid peroxidation products, significantly increased anthocyanin content and had a higher activity of SOD and catalase as compared with non-resistant cultivars. The non-tolerant cultivars’ response to stress agents was only to increase proline content with a simultaneous decrease in SOD activity and anthocyanins content. The identified varietal markers of the antioxidant system adaptive strategy can be used to develop new approaches for screening wheat cultivars with cross-resistance to major abiotic stressors. Keywords: antioxidant system, drought resistan­ce, ferrous sulphate, H2O2, heat tolerance, oxidative stress, Triticum aestivum seedlings

Photogenerated and cocatalytic system cooperate to accelerate Fe3+/Fe2+ cycle in CNFe/FeS2/MoS2 composite with Z-scheme heterojunction constructed by interfacial chemical bond for advanced oxidation processes

Currently, the utilization of Fenton or Fenton-like reactions is prevalent in various domains such as environmental control, biology, and life science. In this study, we drew inspiration from the MoS2 cocatalytic heterogeneous Fenton system and devised CNFe/FeS2/MoS2 heterojunction. This heterojunction is connected through atomic-level Fe-S-Mo and Mo-N interfacial chemical bonds, serving as a catalyst for synergistic photocatalytic effects in conjunction with Fenton reactions. The suitable Mo/Fe molar ratio of 1.5 gives the CNFe/FeS2/MoS2 catalyst higher conductivity and higher carrier separation efficiency. The utilization of dual reduction approaches involving photo-generated electrons and Mo4+ effectively facilitates the stable circulation of Fe3+/Fe2+ with high efficiency in an acidic microenvironment, which is facilitated by the S-SO42- edge of MoS2. Moreover, the CNFe/FeS2/MoS2 heterojunction exhibits enhanced production of ∙O2 and H2O2. This effect not only reduces the quantity of hydrogen peroxide generated but also contributes to cost reduction. This work not only experimentally verifies the coupling effect of heterojunction and cocatalytic heterogeneous Fenton system but also provides a new idea for the design of efficient advanced oxidation processes (AOPs).

Lipid Peroxidation in Ferroptosis and Association with Nonalcoholic Fatty Liver Disease.

Nonalcoholic fatty liver disease (NAFLD) constitutes a commonly diagnosed liver pathology with perturbed lipid metabolism, which is mainly caused by excessive accumulation of fat in hepatocytes by various pathogenic factors. Currently, there are no effective drug treatments for NAFLD. Ferroptosis represents a novel form of programmed cell death depending on iron, which is driven by large cellular amounts of reactive oxygen species (ROS) and lipid peroxides. Ferroptosis plays critical regulatory roles in the pathogenesis of NAFLD, and overaccumulation of Fe2+ contributes to lipid peroxidation, which subsequently aggravates NAFLD. Therefore, ferroptosis suppression might constitute an important target for NAFLD treatment. This article reviews the discovery, production pathways, and defense mechanisms of ferroptosis, and explores its association with NAFLD. This may provide new reference targets and strategies for the development of NAFLD drugs from the perspective of ferroptosis.

Effects of Different Storage Temperatures and Methyl Jasmonate on Grape Quality and Antioxidant Activity

The aim of this study was to find out how different postharvest temperatures and MeJA treatments affected the quality of table grapes, their antioxidant properties, and the amount of hydrogen peroxide and malondialdehyde they contained. For the investigation, postharvest Shine Muscat table grapes were treated with low and high temperatures and MeJA at concentrations of 10 and 100 μmol/L. The results indicated that treating grape berries with MeJA at concentrations of 10 and 100 μmol/L effectively reduced weight loss and mitigated the increase in soluble solid content while also mitigating the decrease in berry firmness and titratable acidity. Consequently, this treatment preserved the sensory and nutritional qualities of the berries and extended their shelf life. Meanwhile, the application of MeJA at a concentration of 10 μmol/L demonstrated superior effectiveness compared to the 100 μmol/L concentration and resulted in a significant enhancement of antioxidant activities by increasing levels of superoxide dismutase, catalase, ascorbate peroxidase, and polyphenol oxidase. Furthermore, the levels of hydrogen peroxide and malondialdehyde in the samples increased for all treatments throughout the storage period. Nevertheless, the levels of hydrogen peroxide and malondialdehyde generation following MeJA treatment remained much lower compared to samples treated at room temperature and low temperature. Therefore, the postharvest application of MeJA at a concentration of 10 μmol/L could play a critical role as a stimulator of fruit quality as well as enhance physicochemical parameters and antioxidant activities for extending the shelf life of grapes during storage.

CATALASE AND PEROXIDASE BIOMIMETIC SENSOR BASED ON Ag-ELECTRODE

Research has been carried out on the development of a biomimetic sensor of the catalase and peroxidase type to determine trace amounts of peroxide hydrogen and low concentrations of ethyl alcohol in an aqueous solution. By potentiometric research, the physicochemical feature of the catalase and peroxidase biomimetic sensor was studied, the transducer of which was Ag. Rapid and accurate determination of hydrogen peroxide is very important, but no less important side of this issue is associated with the determination of trace amounts of C2H5OH in aqueous media of various origins. The need to develop express methods for determining the concentration of C2H5OH in aqueous solutions follows from the requirements for the quality of wine and alcohol products. As you know, the taste and drinking qualities of the product depend on the ratio of methyl and ethyl alcohols. In this work, biomimetic sensors of the catalase and peroxidase types based on an Ag electrode were developed for determining trace amounts of hydrogen peroxide and ethanol. Biomimetic sensors of the catalase and peroxidase types based on an Ag electrode have been developed for the determination of microquantities of hydrogen peroxide and ethyl alcohol. The applicability of a biomimetic sensor for determining trace concentrations of hydrogen peroxide, as well as for determining microquantities of ethyl alcohol in an aqueous solution with a low detection limit, high sensitivity, wide recognition range, high stability, and repeated use, is shown. The developed and synthesized biomimetic sensor of the catalase and peroxidase types based on TPhPFe3+/Al2O3/Ag have high sensitivity, stability, and do not lose their activity for a long time

Influence of Cotton Bleaching Methods on the Parameters of Generated Textile Industrial Wastewater

The environmental impact of industrial wastewater after bleaching requires special attention to prevent the pollution of aquatic ecosystems. The aim of this study was to compare the effluent parameters obtained after using a traditional bleaching method and an alternative enzymatic bleaching method in order to assess their possible environmental impacts. In the classical bleaching method, NaOH and H2O2 were used, and in the alternative method, pectinase enzyme, H2O2, and sodium carbonate were used as the bleaching agents. The bleaching process was designed by determining the optimum amount of pectinase enzyme, the optimum temperature, and the optimum amount of peroxide. The whiteness of the treated cotton yarns was also evaluated. The different bleaching processes were analyzed and evaluated in terms of the wastewater discharged, the pH, chemical oxygen demand (COD), total dissolved solids (TDS), total suspended solids (TSS), and conductivity. These data show that the use of the pectinase enzyme allows us to obtain much lower COD and TSS values compared to those obtained using traditional bleaching. At the same time, the use of the proposed enzymatic bleaching method reduces the environmental impact since lower concentrations of pollutants are obtained in the effluent. Therefore, the pretreatment of wastewater may require the selection of a simpler and more environmentally friendly technology, such as enzymatic bleaching.

Nitrogen-doped reduced graphene oxide/black phosphorus quantum dot composites for electrocatalytic treatment of choroidal melanoma

Choroidal melanoma (CM) is a melanocyte-derived intraocular malignancy that poses a great threat to patients’ vision and life. Electrochemical therapy, which relies on the generation of reactive oxygen species via an oxygen reduction reaction (ORR) to kill target cells, has emerged as a promising approach for the local treatment of malignant tumors. In this study, nitrogen-doped reduced graphene oxide (N-rGO) was electrostatically bound with black phosphorus (BP) quantum dots to form a composite system (N-rGO-BP) for tumor therapy. Owing to the synergistic effect of the two components, the optimal catalyst (N-rGO-BP-12) exhibits improved electrochemical properties and stability, achieving a more positive half-wave potential of 0.66 V and a larger steady-state current density of 2.76 mA cm−2 compared with the N-rGO precursor. In electrochemical therapy, N-rGO-BP-12 undergoes ORR via a two-electron pathway in the acidic microenvironment of the tumor, producing large amounts of hydrogen peroxide and hydroxyl radical to kill tumor cells; only 25 % of the human CM cells survive after 3 h of the treatment. This study provides a new approach for the synthesis and application of electrochemical catalysts for clinical tumor therapy.

NIR-switchable local hydrogen generation by tandem bimetallic MOFs nanocomposites for enhanced chemodynamic therapy.

The inadequate quantity of hydrogen peroxide (H2O2) in cancer cells promptly results in the constrained success of chemodynamic therapy (CDT). Significant efforts made throughout the years; nevertheless, researchers are still facing the great challenge of designing a CDT agent and securing H2O2 supply within the tumor cell. In this study, taking advantage of H2O2 level maintenance mechanism in cancer cells, a nanozyme-based bimetallic metal-organic frameworks (MOFs) tandem reactor is fabricated to elevate intracellular H2O2 levels, thereby enhancing CDT. In addition, under near-infrared excitation, the upconversion nanoparticles (UCNPs) loaded into the MOFs can perform photocatalysis and generate hydrogen, which increases cellular susceptibility to radicals induced from H2O2, inhibits cancer cell energy, causes DNA damages and induces tumor cell apoptosis, thus improving CDT therapeutic efficacy synergistically. The proposed nanozyme-based bimetallic MOFs-mediated CDT and UCNPs-mediated hydrogen therapy act as combined therapy with high efficacy and low toxicity.

Novel valence regulation-vacuum gasification method for separation of selenium and tellurium

It is a general challenge to separate similar elements in material and non-ferrous metallurgical industries. Due to their unique semiconductor properties, selenium and tellurium as well as their separation have been increasingly drawing the attention of worldwide research. Currently, they are mainly extracted and recycled from copper anode slime. The conventional methods used for separating selenium and tellurium have several drawbacks, including low separation efficiency, lengthy processes, and significant environmental pollution. To address these issues, in this paper, the gas-liquid equilibrium (VLE) phase diagram of selenium-base binary alloy at full concentration was drawn according to the theory of gas-liquid equilibrium, the limitation of single vacuum distillation separation technique is theoretically interpreted, and a novel valence regulation-vacuum gasification method is proposed, which shows a superior selenium/tellurium separation rate of 99.98 % and a high material volatilization rate around 90 % achieved with hydrogen peroxide addition. The optimal amount of hydrogen peroxide for the separation process is determined as 1.1 L/kg. The promising results suggest potential of the new method for effectively separating other similar elements.

Photo Degradation of Solochrom Violet Dye by ZnO: Experimental and Theoretical Study

The present project involves photodegrading the dye solochrom violet under advanced oxidation techniques at (25 oC) temperature and UV light. Zinc Oxide (ZnO) and UV radiation at a wavelength of 580 nm were used to conduct the photocatalytic reaction of the solochrom violet dye. One of the factors looked into was the impact of the starting conditions. pH, the amount of original hydrogen peroxide, and the dye concentration time radiation were used. For hours, the kinetics and percentages of degradation were examined at various intervals. In general, it has been discovered that the photodegradation rates of the dye were greater when H2O2 and ZnO were combined with UV light. The best wavelength to use was determined. Modern oxidation techniques were proven to be very effective at degrading the majority of contaminants in wastewater. Using a spectrophotometer, the dye's photocatalytic browning was investigated. The theoretical calculation concentrated on the active site using the density functional theory technique and the Gaussian 09 program.

A double-gain theranostic nanoplatform based on self-supplying H2O2 nanocomposites for synergistic chemodynamic/gas therapy

Chemodynamic therapy (CDT) based on hydroxyl radicals (•OH) to suppress tumor cells is a promising strategy due to its efficacy and safety. Nevertheless, in tumor cells, CDT still faces challenges such as insufficient •OH and weak killing effect of tumor cells under physiological conditions due to inadequate amounts of endogenous hydrogen peroxide (H2O2) and heightened glutathione expression. These challenges limit the therapeutic potential of CDT. To improve the effects of CDT, combination treatment strategies have been developed. Here, we report a rationally designed nanocomposite (CaO2@Cu-LA) with self-supplying H2O2 ability from calcium peroxide, and nitric oxide (NO) generation ability from l-arginine. NO molecules not only exhibit a strong killing effect, but also have the potential to transfer into the more cytotoxic substance peroxynitrite anion by reacting with reactive oxygen species. The results showed that CaO2@Cu-LA could significantly suppress tumor growth by increasing •OH radicals and NO molecules. Taken together, the strategy developed here provides a good application foreground to yield a remarkable synergistic antitumor effect of CDT and NO gas therapy.