Amount Of Fibers Research Articles

Benefits of the Moringa oleifera seed husk as bran for human consumption

Bran is the husk of cereals, crushed by grinding. It is a food that helps improving different symptoms, mainly for the digestive system. Moringa oleifera Lam. It is a plant with a high nutritional value, so the use of Moringa seed husk was evaluated for human consumption and for strengthening foods by producing bran. To characterize the Moringa seed husk for human consumption as bran and emphasize its benefits to health. The bran was produced by grinding Moringa oleifera Lam. seed husks with a sieve of 2.0mm. The proximal composition was made by infrared near spectrocospy. The determination of minerals and metals was done by the method PT-AQ-23 and moisture by the gravimetric method. The bran from Moringa seed husks, allowed to have a product with soft powder characteristics and a slightly sandy feel, of beige color with brown tips, discreetly bitter and fresh wood odor. From the nutritional point of view, it contributed the following compounds: fiber protein, starch and fat; everything comparable or superior to the contents in other bran of wheat, rice, oat and barley, among others. The bran from Moringa seed husk is a highly beneficial product for digestive health due to the quantity of fiber it provides, the high nutritional value of its other properties.

Ultrasound and Steam Explosion Treatments on the Quantity and Molecular Size of Soluble Fibre Obtained from Un-purified and Purified Rice Bran

Rice bran (RB) is a major by-product of the rice industry, and the high proportion (~90%) of insoluble fibre (IF) is the main reason limiting its applications in foods. Thus, the objective of this research is to enhance the solubility of rice bran fibre and decrease the molecular weight (MW) of the soluble fibre (SF) fraction through ultrasound (US) and steam explosion (SE) treatments. The main sugars in the RB fibre were xylose and arabinose, with glucose, galactose, and mannose present in the side chains. The ratio of Ara/Xyl was 0.92 for the un-purified and 1.02 for the purified RB, reflecting the high degree of substitution of the xylan backbone. The highest amount of SF was obtained from RB treated at 60% US amplitude, 20 min treatment, where 7.8% (un-purified) and 35.2% (purified), respectively. For SE treatments, the amount of SF in un-purified RB increased as the pressure increased from 0.3 and 0.6 MPa, which were 6.10±0.34 and 8.83±0.56%, respectively. Meanwhile, the highest SF fraction (35.2%) of purified RB was obtained from the SE treatment at 0.6 MPa. The SF produced from both treatments mainly contained oligosaccharides with MW <1 kDa, with those produced by the SE treatment generally smaller than those by the US treatment. Purification of RB significantly enhanced the efficiency of the US and SE treatments in breaking down the IF into the SF.

Thermal Insulation Properties of Milkweed Floss Nonwovens: Influence of Temperature, Relative Humidity, and Fiber Content

This study investigated the influence of fiber content, temperature, and relative humidity on the thermal insulation properties of nonwoven mats made of seed fibers from Asclepias Syriaca, commonly known as milkweed floss. Nonwoven mats with a 1-inch thickness were produced by uniformly arranging milkweed fibers within a mold. Various quantities of fiber were employed to obtain nonwoven mats with a fiber content ranging from 5 to 35 kg/m3. Thermal conductivity and thermal diffusivity were measured across diverse relative humidity levels and temperatures. Simultaneously, milkweed floss samples were exposed to identical environmental conditions to assess the moisture regain and specific heat capacities of the fiber. The specific heat capacity of milkweed and thermal conductivity of the nonwovens exhibited a linear increase with temperature. The thermal diffusivity and thermal conductivity of the nonwovens decreased with rising fiber content. The thermal insulation properties of the nonwovens remained partially stable below 30% relative humidity but substantially deteriorated at higher levels. The nonwovens exhibited optimal thermal insulation properties at a fiber content between 20 and 25 kg/m3. The results of this study highlighted several technical advantages of employing milkweed floss as a sustainable and lightweight solution for thermal insulation.

Sarcopaenia

Sarcopaenia is a common condition characterized by loss of muscle mass presenting with muscle weakness and loss of strength. Progressive and widespread decline in both skeletal muscle mass and strength can result from natural aging process andor prolonged periods of immobility. Muscle mass loss encompasses a decline in both the quantity of muscle fibers and a reduction in their individual sizes. The rate at which muscle loss occurs is influenced by various factors including ones level of physical activity the loss or presence of concurrent medical conditions dietary habits and other relevant factors. Sarcopaenia influences the health of the individual through frailty and disability. Sarcopenia is frequently linked with reduced endurance lack of physical activity diminished walking speed impaired balance and decreased overall mobility. There is difficulty in climbing stairs and increased risk of falls in elderly. It affects their functional independence.

Use of plastic waste as recycled material in the concrete

In this study, we examined the effect of adding recycled plastics to concrete. The waste plastics were collected from a local market. The disposal of plastics is a major issue with many negative consequences. Plastic, being inorganic, does not change the chemical characteristics of concrete and has no effect on its quality or consistency, making it an ideal material for use in the construction industry, where it may help reduce plastic waste. Plastic has dual uses in concrete as a filler ingredient and as an additive to enhance the mechanical properties of the material. The concrete was prepared using five different amounts of aggregate substitution by volume: 10%, 20%, 30%, 40%, and 50%. Cubes and beams were cast, cured, and tested using a universal testing machine. A mixed proportion was made using the different ingredients used in the concrete. At 7, 21, and 28 d, the results showed that the compressive and flexural strengths increased as the percentage of plastic waste increased. Also, flexural strength improved with an increase in the proportion of plastic waste, reaching a maximum at 30%. These results highlight that, as plastic fiber decreases the quantity of industrial fibers needed in concrete, it is also proven to be more inexpensive.

Transforming Polycotton Textile Waste into New Bicomponent Fibers: An Investigative Study

This study aimed to develop an innovative recycling method for end‐of‐life polycotton textiles, eliminating the need for component separation. The use of 1‐ethyl‐3‐methylimidazolium acetate ([EMIM][Ac]) as an ionic liquid solvent facilitated the dissolution of cotton, enabling the creation of a spinning dope containing cellulose and polyester fibers. Successful spinning of bicomponent fibers ensued, followed by comprehensive fiber evaluation. The dissolution of cotton was achieved with [EMIM][Ac], and spinning trials were conducted to devise a suitable method for regenerated cellulose. Tensile tests on the produced cellulosic fibers clearly demonstrated an increase in tensile strength with higher cellulose concentration. The introduction of polyester fibers to the spinning dope, comprising [EMIM][Ac] and cotton, posed challenges to the entire spinning process. Tensile tests on the resulting bicomponent fibers revealed a decrease in tensile strength compared to pure regenerated cellulose fibers. This reduction was attributed to increased voids and irregular polyester fiber distribution, corroborated by microscopy images and a wicking test. It was concluded that the quantity and length of polyester fibers significantly influenced the tensile strength of the bicomponent fibers, with lower concentrations and shorter fibers resulting in higher strength.

Qualitative characteristics of cashmere fiber of Chyangra goat of Nepal

This study assesses the different physical characteristics of cashmere fiber quality in Chyangra goats as wax percentage, length of pashmina fiber, fineness (diameter) of fiber obtained from different body parts (neck, belly, and back) in different locations of Mustang district of Nepal. In mid-March to mid-April 2022, cashmere samples were collected from thirty-four unrelated animals. Twenty-two animals were sampled from Upper Mustang and twelve were sampled from Lower Mustang; of which, 22 were male and 12 were female of 1, 2, 3, 4, and greater than 4 years of age. Cashmere fiber length was measured using measuring pad and ruler and fiber diameter was analyzed using the optical projection microscope method. The fixed effect model was used to analyze the least square mean for fiber length, diameter and wax percentage of Chyangra cashmere fiber considering various factors such as location, sex and age. The overall least square mean and standard error for fiber quality parameters namely wax percentage, fiber length and fiber diameter were 9.49±2.2%, 45.97±0.14 mm and 15.36±0.19 µm respectively. Even though there is a significant difference in the considered parameters by location, the fineness and length of the fiber of both locations was within the finest fiber ranging from 13-16 µm diameter and more than 40 mm length. The present study has evidenced that Chyangra goat of Nepal can be characterized as one of the finest Cashmere goats however some management steps must be taken to improve the quality (cleanliness) of fiber and the volume of fiber production. Significant differences were found in location, sex, and trend of difference in age of the animals indicating the potential to improve cashmere quality by adopting proper management and selection methods through selection of goats with larger body size and confirmation to obtain more quantity of fiber per animal.

Treatment Strategy for Currarino Syndrome Complicated With Anorectal Stenosis.

The present study aimed to review the treatment experience and outcomes of Currarino syndrome (CS) complicated with anorectal stenosis to evaluate the current treatment strategies. Seven cases of CS complicated with anorectal stenosis, treated at our hospital between 1998 and 2021, were retrospectively investigated. This is a case series article from a single institution. In six and three cases and one case, the presacral mass was a mature teratoma, meningocele, and lipoma, respectively. Resection of the lesion was performed in all six cases of mature teratoma, and duraplasty was performed before resection in all three cases of meningocele. Moreover, surgery for anorectal stenosis was performed simultaneously in four patients. Surgery was performed for six cases of anorectal stenosis, with the remaining case relieved by dilation using a metal bougie. The surgical methods used were a partial resection with end-to-end anastomosis, anorectal strictureplasty, pull-through, posterior sagittal anorectoplasty, and cutback after mass resection. Pathological analysis of the anorectal stenoses revealed disorganized and rough smooth muscle fibers and the replacement of the stroma by an increased quantity of collagen fibers. The clinical outcomes of CS can be improved by establishing a treatment flow chart and understanding the complicated pathophysiology of the disease.

Influence of Citrus sinensis seed powder on growth performance, morphological and histological development of the small intestine of broiler chickens

Citrus sinensis (sweet orange) seeds are sources of significant quantities of bioactive compounds and dietary fiber which have shown a range of biological activities in humans but are essentially discarded with abundant waste production. The aim of this study was to evaluate the impact of C. sinensis seed powder on the morphological and histological development of the small intestine of broiler chickens. Four hundred and eighty (480) day-old Cobb 500 broilers chicks were divided into four groups with six replicates and 20 chicks per pen, namely control (T): fed only standard diet; CSS-0.25: standard diet + 0.25% C. sinensis seed powder; CSS-0.50: standard diet + 0.5% C. sinensis seed powder; CSS-0.75: standard diet + 0.75% C. sinensis seed powder over 42 days in a completely randomized design. The results indicated that a diet containing 0.75% of C. sinensis seed powder significantly (p < 0.05) increased the weight and length of the small intestine and its three segments. Furthermore, villi height, villi/crypt ratio, and crypt depth in the jejunal and ileal sections of the intestine increased significantly (p < 0.05) with 0.5% and 0.75% C. sinensis seed powder supplementation. In addition, weight gain and feed conversion ratio were significantly affected in the 0.5 and 0.75% groups on days 21 and 42. In conclusion, supplementation with 0.5% and 0.75% C. sinensis seed powder improves intestinal development and intestinal health in chickens.

The Quantity and Quality of Flax and Hemp Fibers Obtained Using the Osmotic, Water-, and Dew-Retting Processes

This study presents the quantity and quality of flax (Linum usitatissimum L.) and hemp (Cannabis sativa L.) fibers obtained depending on the fiber extraction method. The extraction methods used in this study were osmotic degumming, dew retting, and water retting. The degummed straw was analyzed for fiber content, while the metrological, chemical, and physical properties were determined for the fibers obtained. It was shown that these properties change based on the method of fiber extraction used. The highest fiber content in the straw was obtained using the osmotic degumming method. These fibers are characterized by a light color, no unpleasant odor, low linear mass, good tenacity, lowest hygroscopicity, and reduced flammability compared to fibers obtained via the dew and water retting of straw.

Fibres in the nasal cavity: A pilot study of the recovery, background, and transfer in smothering scenarios

In cases where the suspected cause of death is smothering, fibre traces recovered from the nasal cavity are hypothesised to refute or support this proposition. In order to carry out such evaluations, an efficient recovery method must first be established. This pilot study tested five different recovery methods on 3D printed models of nasal cavities. Among which, the use of the transparent AccuTrans® polyvinyl Siloxane casts demonstrated the best recovery efficiency with a median of 90% of deposited fibres recovered. The efficacy of this method was then verified on cadavers. Apart from a reliable recovery method, an understanding of the background population of fibres in nasal cavities, as well as the mechanisms of the transfer from the purported smothering textile to the nasal cavity is essential to evaluate the findings in these cases of suspected smothering. Samplings of the nasal cavities of 20 cadavers were thus carried out to gather data on the background population of fibres. Results showed that nasal cavities are not void of fibres, but the quantities are expected to be low, with a mean of 3.8 fibres per cavity recovered. Information on generic fibre class, colour, and length of these background fibres were also obtained with the use of low and high-power microscopy. The frequencies found in this population of fibres closely align with data from other population studies where black cotton was the most common. Finally, transfer experiments using the 3D printed models fitted with a respiratory pump to simulate breathing were carried out, along with testing on live volunteers in-vivo. The results demonstrated a verifiable transfer of fibres into the nasal cavity in smothering scenarios. Textiles of various shedding capacities were used in these tests and the findings suggest an influence of this variable on the quantities of fibres transferred.

Effect of free and embedded polypropylene fibres recovered from concrete recycling on the properties of new concrete

This study aims at investigating the effect of incorporating different quantities of polypropylene fibres recovered during concrete recycling or embedded in recycled aggregates on the mechanical properties of new polypropylene fibre-reinforced concrete (PPFRC). Both recovered fibre (at replacement ratios of 0 %, 10 %, 30 % and 100 %) and recycled coarse aggregate (0 %, 100 %) were used in new concrete. Polypropylene fibre contents of 3 and 9 kg/m3 (0.33 % and 1.0 % by volume, respectively) were chosen for all concretes. The properties of recovered and virgin fibres were tested to determine the effect of recycling on fibre properties. The compressive strength, elastic modulus and stress–strain behaviour in compression were tested and a constitutive model was developed to fit the stress–strain behaviour of the PPFRC with mixed recovered and virgin fibres. The residual tensile strength was also tested for concretes with recovered fibres and fibres embedded in recycled aggregate. The results show that mixing of recovered and virgin fibres is feasible without significant effect on mechanical properties of concrete. At the same time, inclusion of recycled coarse aggregate from PPFRC recycling contributes to residual tensile strength through the presence of fibres embedded in the aggregate.

Effect of kapok/polypropylene needle punched nonwoven and chicken feather fiber wadding on thermal insulation applications

Thermal resistance of cold-weather clothing is achieved by layering and filling. In this study, kapok/polypropylene blended (70/30, 60/40, and 50/50) needle-punched nonwovens were manufactured with 100 and 200 g/m2 areal density. Chicken feather fibers were used as fillers for developing quilted composite structures (QCS). To produce a QCS, 100 and 200 g/m2 nonwovens were individually used as the top and bottom layers, and the middle layer was filled with chicken feather fibers in 100, 200, 350, 550, 600, and 850 g by weights. The structures were characterized for thermal properties, and it was noted that 70/30 kapok/polypropylene nonwovens in 100 g/m2 set had the highest thermal resistance between 0.5901–0.6461 °C m2/W. Thermal resistance is greatly influenced by kapok, chicken feather fiber quantity in the assembly along with the areal density (1000 g/m2) of the QCS. Results show that the developed QCS has higher thermal insulation and can be used for cold-weather apparel and sleeping bag.

Effect of Block Size on Bearing Strength of Steel Fiber-Reinforced Recycled Aggregate Concrete

For the safe transmission of loads to concrete supports, such as column-foundations, corbels, bridge pedestals, post-tension members, support anchorages, and other forms of superstructure supports, the concrete bearing strength is considered an essential design parameter. The usage of recycled aggregate within concrete is considered environmentally friendly since it diverts rubbish from bulldozing and preserves natural resources. End-hooked steel fibre is an almost substantial enhancer for recycled aggregate concrete characteristics. Never before has the bearing behavior of recycled aggregate concrete been evaluated. Thus, this study provides an experimental evaluation of the bearing strength of steel fiber-reinforced recycled aggregate concrete at different replacement levels (0, 10, 20, 30, 50, and 100%) of recycled concrete aggregate (RCA). The used fraction quantities of steel fiber were 0.5%, 1.5%, and 2%. Three sizes of blocks were manufactured (100 × 100 × 100 mm, 150 × 150 × 150 mm, and 250 × 250 × 250 mm). The ratio of concrete block area to bearing area (A2/A1) was kept constant at 2.5 for all three block sizes. The primary purpose of this research was to examine the impact of block size on bearing stiffness, ultimate slip, and ultimate bearing strength. The findings demonstrated that the bearing stiffness and bearing strength reduced as the block size increased. To assess the ultimate bearing stiffness/strength and normalised ultimate bearing slip, analytical models were employed to develop new proposed equations that unaccounted for the impact of compressive strength, RCA, reinforcing index of steel fibre, and block size. In addition, this research led to the creation of a modified ACI 318 formula that accurately forecasts the bearing strength of concrete depending on block size.

Experiment on Concrete by Adding Steel Fibers and Plastic Waste to Reduce Environmental Issues and Adding Strength to Concrete

Abstract: Concrete is the most commonly used material for construction in civil engineering. The project involves the proposed concrete which is made up of adding plastic in concrete may help to reuse the plastic as one of the constituent material of concrete. Due to rapid industrialization the amount of use and decomposition of plastic has increased. If we are able to utilize this waste under proper conditions as addition to concrete it will reduce the plastic waste up to some extent. By adding the steel fibers to the above mix it will increase the compressive strength of the concrete. M40 grade concrete is used in the whole procedure. Here, we used 4 different percentages of plastic waste (i.e., 0.6%, 1.2%, 1.8%, and 2.4%) of weight of cement and by taking quantity of steel fiber as constant (i.e., 2%) of weight of cement, and the aspect ratio of steel fibers is 60. The concrete cube of size 150mm×150mm ×150mm are prepared and tested at 3days, 7days, 14days and 28 days. The resulting data has been analyzed and compared with controlled specimens.

Normalization of protein and carbohydrate nutrition for high productive cows during a dry period

The article provides the results of study of protein and carbohydrate nutrition for high productive cows with milk yield of 10 thousand kg during dry period. There has been carried out the research for determining the feed protein disintegration and effectiveness of its use in cow rations. The carbohydrate nutrition for Holstein-Kholmogory cows during dry period taking into account quantity and quality of neutral detergent fiber (NDF) and acid detergent fiber (ADF) was studied. The science-economic experiment was conducted in the “Polyarnaya Zvezda”, Murmansk region in 2015 and 2021. The disintegration of feed crude protein (DP) was determined by the in sacco method, by incubation of average samples of single feeds in nylon bags in the rumen during 12 hours. Content of crude protein in feed samples before and after incubation was determined by the content of total nitrogen by the Kjeldahl method. Digestibility in the intestine of feed protein not disintegrated in rumen was determined by the mobile synthetic bag method. NDF and ADF were determined by the method of Van Soest and Southgate modified by N. N. Semina. In the experiment of protein nutrition, the content of crude protein in the ration of control and experimental groups of cows was 16 %. The content of disintegrated protein in the control group was 59.0 %, in the experimental group – 67.0 %. In the experiment of carbohydrate nutrition, in the control group crude fiber was 19.4 %, neutral detergent fiber – 38.9 %, acid detergent fiber – 23.0 % of dry matter. In the ration of experimental group of cows, the content of crude fiber was 22.4 %, neutral detergent fiber – 47.2 %, acid detergent fiber – 27.6 %. Animals of the experimental group whose ration had a crude protein disintegration of 67.0% used nitrogen more efficiently, utilized a nutritious of ration better. During the research it has been established, that the content of neutral detergent fiber of up to 47.2 % and acid detergent fiber of up to 27.6 % results in increase in digestibility of ration nutritious, improves nitrogen metabolism, intensify microbiological activity in cow rumen.

Peeling Force Required for the Detachment of Non-Woven Plastic Tissue from the Surface of Mortar Prisms.

The purpose of this experimental paper is to examine the adhesion properties between non-woven plastic sheets and cement mortar. Specifically, the effect of w/c ratio and quantity of superplasticizer on the peeling force required for the detachment of tissue from the surface of prisms was studied in detail. Therefore, two types of mortar mixtures were prepared: (1) mixtures without superplasticizer with three different w/c ratios of 0.45, 0.50, and 0.55, and (2) mixtures with reduced amounts of water and three various percentages of superplasticizer of 0.0%, 1.11%, and 2.17% (by weight of cement). For this purpose, bond tests with a special setup, interferometry and microscopic analyses, and mechanical tests were performed. The results highlight that non-woven sheets had strong adhesion to cement mortar without using any adhesive materials. However, the peeling force improved by 15.78% as the w/c ratio increased from 0.50 to 0.55. Conversely, this force declined by 24.50% as the w/c ratio decreased from 0.50 to 0.45. In addition, the peeling force decreased by 20.62% as the w/c ratio decreased from 0.50 to 0.45 and 1.11% superplasticizer was added to the mixtures. This property decreased further by 38.29% as the w/c ratio lowered to 0.40, and the amount of superplasticizer increased to 2.17%. The interferometry and microscopic analyses clearly demonstrate that the adhesion between tissue and mortar is largely related to the surface texture, amount of cement paste, and quantity of residual fibers on the surfaces of samples. It indicates that mortar samples with higher w/c ratios had a smoother surface, and providing more contact area for microfilaments, which resulted in thicker layers of remaining fibers compared to the specimens with a lower w/c ratio. Even though there was not much difference in the surface texture of specimens with superplasticizer and lower w/c ratios, because of their similar workability. Still, thicker layers of microfilaments remained on the surface of specimens containing a lower amount of superplasticizer, which resulted in strong adhesion between sheet and cement mortar.

Comparative study of physicochemical and functional properties of different buckwheat varieties and their milling fractions

The present work evaluated the physicochemical and functional characteristics of different indigenous buckwheat varieties grown in Gilgit Baltistan, Pakistan, using grains and milled flour (fine flour, coarse flour, bran, and husk). Results showed that the thousand grain weight, length, width, thickness, arithmetic mean diameter, and geometric mean diameter were found to be highest in common buckwheat. In contrast, the highest mean values for sphericity were observed in Tartary buckwheat. The water absorption capacity, oil absorption capacity, swelling capacity, foaming, and foaming stability were high in common buckwheat as compared to Tartary buckwheat. Results regarding chemical properties revealed that common buckwheat contained higher quantity of protein (14.67%), fat (3.86%), fibre (1.38%), ash (2.24%), and total carbohydrate (65.8%); while Tartary buckwheat contained moisture (13.31%), protein (11.9%), fibre (1.38%), fat (3.57%), ash (2.69%), and total carbohydrate (68.8%). Furthermore, during the comparison of milling factions, it was found that buckwheat husk contained the highest quantity of copper (6.78 mg/100 g) and manganese (32.79 mg/100 g), while fine flour proved to be a rich source of magnesium. The present work identified variability among buckwheat varieties and milling fractions for physicochemical and nutritional traits that could be used to supplement various food products as functional ingredients.

Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease

BackgroundAlzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Impaired autophagy in plaque-associated microglia (PAM) has been reported to accelerate amyloid plaque deposition and cognitive impairment in AD pathogenesis. Recent evidence suggests that the transcription factor EB (TFEB)-mediated activation of the autophagy–lysosomal pathway is a promising treatment approach for AD. Moreover, the complementary therapy of intermittent hypoxia therapy (IHT) has been shown to upregulate autophagy and impart beneficial effects in patients with AD. However, the effect of IHT on PAM remains unknown.Methods8-Month-old APP/PS1 mice were treated with IHT for 28 days. Spatial learning memory capacity and anxiety in mice were investigated. AD pathology was determined by the quantity of nerve fibers and synapses density, numbers of microglia and neurons, Aβ plaque deposition, pro-inflammatory factors, and the content of Aβ in the brain. TFEB-mediated autophagy was determined by western blot and qRT-PCR. Primary microglia were treated with oligomeric Aβ 1–42 (oAβ) combined with IHT for mechanism exploration. Differential genes were screened by RNA-seq. Autophagic degradation process of intracellular oAβ was traced by immunofluorescence.ResultsIn this study, we found that IHT ameliorated cognitive function by attenuating neuronal loss and axonal injury in an AD animal model (APP/PS1 mice) with beta-amyloid (Aβ) pathology. In addition, IHT-mediated neuronal protection was associated with reduced Aβ accumulation and plaque formation. Using an in vitro PAM model, we further confirmed that IHT upregulated autophagy-related proteins, thereby promoting the Aβ autophagic degradation by PAM. Mechanistically, IHT facilitated the nuclear localization of TFEB in PAM, with TFEB activity showing a positive correlation with Aβ degradation by PAM in vivo and in vitro. In addition, IHT-induced TFEB activation was associated with the inhibition of the AKT–MAPK–mTOR pathway.ConclusionsThese results suggest that IHT alleviates neuronal damage and neuroinflammation via the upregulation of TFEB-dependent Aβ clearance by PAM, leading to improved learning and memory in AD mice. Therefore, IHT may be a promising non-pharmacologic therapy in complementary medicine against AD.Graphical

Development of Nutririch Brown Rice Kichidi Mix for Geriatric Subjects Residing in Oldage Institutions of Bangalore District, India

Nutrition awareness was carried on in the old age institutions, which was one of the study area of the research. Brown rice is not only better for us, but it's better for the environment than white rice too. brown rice production is relatively sustainable, there is no known significant damage to air, water, land, soil, forests, etc. The study aimed at development of nutri-rich brown rice kichidi mix for geriatric subjects living in old age institutions located in Bangalore. The mean sensory score of the brown rice kichadi mix where BKM 3 variation having 60g of brown rice and 20g of green gram dhal had the best overall acceptability (8.31) in all the parameters: appearance (8.28), colour (8.03), texture (8.12), aroma (8.12) and taste (8.18). Extremely significant difference was observed in taste and overall acceptability and significant distinction was observed in texture. Nutrients composition of the brown rice kichadi mix consisted of energy 293. kcal, carbohydrates 73.29 g, protein 12.31 g and fat of 4.07 g and met the ¼th of RDA requirement of the geriatric subjects followed by moisture 6.35 per cent, and negligible quantity of crude fibre 3.96 g and ash 1.17 g. The kichadi mix contained fair amount of minerals: calcium 7.94 mg, magnesium 5.93 mg, iron 0.87 mg and zinc of 0.65 mg. Nutritional education using charts prepared based on practice of fine daily activities and importance of nutrients and nutrition taught to the 91 geriatric subjects (31 males and 60 females respectively). The ready to cook brown rice kichadi mix contained most of the food groups and provided for taste by the subjects. Majority of the geriatric subjects participated in the intervention had extremely accepted the product based on taste and consistency.