The general chemical composition of the roots of Decalepis Hamiltonii has been studied. The petroleum ether extract of the Decalepis roots was found to contain (1) a ketonic substance melting at 83–84°, resinol fractions melting between 130 and 185°, a definite compound of the same group melting at 235–36°, sterols and para methoxysalicylicaldehyde. The subsequent alcohol extract contained besides saponins and tannins a crystalline resin acid melting at 245°, an amorphous resin acid melting at 180° and inactive inositol.