The paper presents the results of comparative analysis of the data regarding the multi-instrumental borehole monitoring data of changes in the geoenvironment stress-strain state and GPS data obtained in the time vicinity of the close strong Zhupanovsky earthquake. The purpose this study was to assess the feasibility of using GPS measurements on routine basis for effective monitoring of strong Kamchatka earthquakes in the area of Petropavlovsk-Kamchatsky. The Zhupanovsky earthquake active phase was chosen as a "test" time interval for comparing GPS and borehole monitoring data. This earthquake has been the strongest seismic event since 2000 in terms of the ratio of the earthquake focus length to the hypocentral distance. The time series borehole electromagnetic and geoacoustic data were compared with the dilatation series reflecting the relative changes in the area of a triangle composed of Kamchatka GPS observation network located in the Petropavlovsk geodynamic testing site. The analysis indicates a high degree of consistency in these time series. GPS data obtained during the active phase of the earthquake preparation is agree with the results of mathematical modeling expected values of volumetric strain on the daylight surface on the eve of the earthquake. A joint analysis of borehole and GPS data made it possible to specify the time limits for the stages of change in the stress-strain state of geoenvironment and to resolve ambiguity of interpretation of the electromagnetic and geoacoustic borehole measurement results at the final stage of preparing the Zhupanovsky earthquake.