High entropy alloy coatings with a unique microstructure and excellent mechanical properties show significant potential for development in friction-related applications. In this study, the microstructure, phases, hardness and tribological behavior of FeCoNiCrMox (x = 0, 0.2, 0.5, 1.0) coatings fabricated by HVAF spraying were investigated. The coating changes from a single FCC structure (x=0, 0.2) to a dual phase structure of FCC and σ (x=0.5, 1), accompanied by an expansion in the segregation regions of Cr and Mo elements. The hardness of coatings increased with higher Mo content. Tribology tests were carried out at room temperature using Si3N4 ceramic and GCr15 steel as counterfaces. The results demonstrate that, when paired with GCr15, the wear resistance of the coatings scale proportional with hardness. However, when paired with Si3N4, the coating wear rate exhibits an initial increase followed by a decrease. Notably, the FeCoNiCr and FeCoNiCrMo0.2 coatings exhibited milder friction and wear behavior when in contact with Si3N4 compared to GCr15 steel, attributed to the dominant oxidative wear. This study provides new insights and directions for the design of customized high-entropy alloy coatings based on specific friction conditions.