Objective To explore the nursing experience of inhalation of steroid for patients after endoscopy surgery. Methods From September to December 2016, we selected 200 patients with transnasal endoscopic frontal surgery of Allergy Department at Beijing Tongren Hospital, Capital Medical University as subjects. All of the patients were treated with the inhalation of glucocorticoid. Nurses provided the guidance of inhalation of steroid for patients and observed the effects. Results A total of 200 patients accepted inhalation. After inhalation, patients' subjective symptoms improved. A total of 182 patients were very satisfied with the nursing service and 18 patients were satisfied with the nursing service. Three months after surgery, there were 152 patients without edema, 24 with the mild edema and 24 with obvious edema in operation cavity of patients. Conclusions Reasonable guidance by nurses can optimize the effects of inhalation of steroid, promote the recovery of patients after surgery and improve patient satisfaction. Key words: Sinusitis; Nasal septum deviation; Endoscopy surgery; Inhalation