Frequency Of Alcohol Drinking Research Articles

A longitudinal study of alcohol consumption among adults in Victoria, Australia during the COVID-19 pandemic.

Whilst public health measures were effective in reducing COVID-19 transmission, unintended negative consequences may have occurred. This study aims to assess changes alcohol consumption and the heavy episodic drinking (HED) during the pandemic. Data were from the Optimise Study, a longitudinal cohort of Australian adults September 2020-August 2022 that over-sampled priority populations at higher risk of contracting COVID-19, developing severe COVID-19 or experiencing adverse consequences of lockdowns. Frequency of alcohol consumption (mean number of days per week) and past-week HED were self-reported. Generalised linear models estimated the association between time and (1) the frequency of alcohol consumption and (2) heavy episodic drinking. Data from 688 participants (mean age: 44.7 years, SD:17.0; 72.7% female) and 10,957 surveys were included. Mean days of alcohol consumption per week decreased from 1.92 (SD: 1.92) in 2020 to 1.54 (SD:1.94) in 2022. The proportion of participants reporting HED decreased from 25.4% in 2020 to 13.1% in 2022. During two lockdown periods, known as "lockdown five", (OR:0.65, 95%CI [0.47,0.90]) and "lockdown six" (OR:0.76, 95%CI [0.67,0.87]), participants were less likely to report HED. Participants alcohol drinking frequency and HED decreased during the pandemic. This study provides a strong description of alcohol consumption during the pandemic and suggests that lockdowns did not have the unintended consequences of increased alcohol consumption.

Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study

BackgroundDepression is a major contributor to the global burden of diseases, and alcohol intake is often considered to be associated with depression. However, the relationship between alcohol drinking frequency and depression remains unclear. This study aims to explore the association between alcohol drinking frequency and depression.MethodsThis study collected NHANES data from 2009 to 2016, involving 17,466 participants. Depression was diagnosed based on the Patient Health Questionnaire-9 (PHQ-9), and alcohol drinking frequency was collected through questionnaire surveys. Multifactorial logistic regression models, subgroup analysis, smooth curve fitting, and threshold effect analysis were used to investigate the relationship between alcohol drinking frequency and depression.ResultsWe divided the alcohol drinking frequency into five groups on average. After adjusting for all covariates, the Q3 group had the lowest odds of depression (OR = 0.68; 95% CI: 0.56 ~ 0.82; p < 0.05). Through smooth curve fitting, we found an “M-shaped” relationship between alcohol drinking frequency and depression. Further threshold effect analysis revealed that the most significant inflection points were 80 and 150.ConclusionIn this cross-sectional study of American adults, we found an “M-shaped” relationship between alcohol drinking frequency and depression, which may partially explain the different effects of moderate alcohol consumption on depression.

Association between insulin resistance indices and kidney stones: results from the 2015-2018 National Health and Nutrition Examination Survey.

To explore the association between representative insulin resistance (IR) indices and the risk of kidney stone disease in an American adult population. The representative IR indices referred to metabolic score for IR (METS-IR), triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, triglyceride glucose-body mass index (TyG-BMI), visceral adiposity index (VAI), and homeostatic model assessment of IR (HOMA-IR). We investigated adult participants who joined the 2015-2018 National Health and Nutrition Examination Survey (NHANES) and reported kidney stone histories. Weighted proportions, multivariable regression analysis, and restricted cubic splines were used to evaluate the associations between IR indices and kidney stones after their adjustment for gender, age, race, education, smoking status, alcohol drinking frequency, hypertension and diabetes status, physical activity level, water intake, and levels of calcium, cholesterol, and uric acid. A total of 19,225 participants were included. The weighted prevalence of kidney stone was 11.1%. A multivariable logistic regression model showed a dose-response relationship between the METS-IR and kidney stone [odds ratio (OR) = 1.02, 95% confidence interval (CI) (1.01, 1.04), p < 0.01]. A similar relationship was observed between the TyG-BMI and kidney stone after full adjustment [OR = 1.0, 95% CI (1.0, 1.01), p < 0.001]. Sex-stratified analyses revealed that the association between METS-IR and nephrolithiasis [OR = 1.03, 95% CI (1.01, 1.05), p < 0.01], and the association between TyG-BMI and nephrolithiasis [OR = 1.01, 95% CI (1.0, 1.01), p <0.001] was significant among the male participants in the fully adjusted model. Moreover, a significant association was found between the METS-IR levels and nephrolithiasis [OR = 1.03, 95% CI (1.01, 1.06), p < 0.01], and between the TyG-BMI levels and nephrolithiasis [OR = 1.01, 95% CI (1.0, 1.01), p < 0.05] among the diabetic participants after full adjustment. Furthermore, a potential nonlinear association was found between other IR indices (i.e., TG/HDL-C, VAI, and HOMA-IR) and the risk of kidney stone disease. Higher METS-IR and TyG-BMI levels were associated with a higher risk of nephrolithiasis. Future investigations are required to identify the role of IR in the progress of kidney stone formation and to propose prevention measures and health guidelines.

Eating habits and dietary supplement utilization according to food-related lifestyle among Korean adults: a cross-sectional study

Objectives: This study investigated the association between eating habits and the utilization of dietary supplements (DSs) according to food-related lifestyle (FRL) among Korean adults. Methods: This study included a total of 300 participants (150 men and 150 women) in their 20s to 60s living in Seoul and Gyeonggi Province. We identified two groups by factor and cluster analysis: an ‘active pursuit’ group and a ‘passive pursuit’ group. Differences in eating habits and DS utilization between the two groups were analyzed by chi-square test and t-test. Logistic regression analysis was used to analyze the effect of variables on DS consumption according to FRL. Results: There were significant differences between the two groups in terms of age, alcohol drinking frequency, total dietary score, change in DS consumption after coronavirus disease 2019, and current DS consumption (P &lt; 0.05). The proportion who perceived many health benefits of DSs was higher in the ‘active pursuit’ group than in the ‘passive pursuit’ group (P = 0.003). The most commonly consumed type of DSs was multivitamins &amp; minerals for the ‘active pursuit’ group, and omega-3 fatty acids for the ‘passive pursuit’ group. The ‘an active pursuit’ group consumed DSs 2.93 times more (95% confidence interval [CI]: 1.44–5.97) compared to the ‘passive pursuit’ group, after adjusting for confounders. In the ‘active pursuit’ group, the health pursuit (odds ratio [OR] = 6.54, 95% CI: 1.44– 29.61) and rational consumption pursuit factors (OR = 0.26, 95% CI: 0.08–0.83) were associated with DS consumption, whereas only the health pursuit factor had a significant association (OR = 5.37, 95% CI: 2.08–13.88) within the ‘passive pursuit’ group. However, total dietary score and DSs consumption did not show a relationship. Conclusions: By understanding the consumption characteristics of DSs according to FRL, this can serve as basic data necessary for promoting health through the utilization of DSs and healthy behaviors.

Alcohol and Binge Drinking Frequency and Hypertension: A National Cross-Sectional Study in the U.S.

The relationship between alcohol consumption and hypertension is multifaceted and a major public health concern. The association becomes even more complicated when hypertension is undiagnosed. This study investigates how alcohol consumption patterns are linked to measured, diagnosed, undiagnosed, and composite hypertension (any indications of hypertension from blood pressure readings, professional diagnosis, or reported medication use) in the United States. Data from the National Health and Nutrition Examination Survey 2015-2020, a nationally representative cross-sectional study, were analyzed in 2023-2024. The final analytic sample was 12,950 participants. Complex-survey weighted multivariable linear and logistic regression models estimated the effect of different alcohol consumption levels on hypertension. Descriptive findings show that those who consumed alcohol more than 3 times weekly exhibited the highest prevalence of measured (52.5%), undiagnosed (27.0%), and composite hypertension (69.4%) compared to other levels of alcohol drinking. Multivariable linear regression analysis indicated a notable elevation in systolic (4.8 unit) and diastolic (2.46 unit) blood pressure among individuals with frequent binge drinking episodes compared to individuals with infrequent drinking. Logistic regression models estimated that drinking over 3 times weekly increases the odds of measured, undiagnosed, and composite hypertension by 64%, 70%, and 54%, respectively, while frequent binge drinking episodes raise these odds by 82%, 65%, and 47%. Contrary to some studies suggesting moderate alcohol intake has protective cardiovascular effects, the findings did not corroborate a "J-shaped" curve. This underscores the importance of regular blood pressure monitoring among individuals with binge drinking episodes and emphasizes the need for public health interventions to mitigate alcohol consumption and its associated hypertension risks.

The Health4Life e-health intervention for modifying lifestyle risk behaviours of adolescents: secondary outcomes of a cluster randomised controlled trial.

To investigate the effectiveness of a school-based multiple health behaviour change e-health intervention for modifying risk factors for chronic disease (secondary outcomes). Cluster randomised controlled trial. Students (at baseline [2019]: year 7, 11-14 years old) at 71 Australian public, independent, and Catholic schools. Health4Life: an e-health school-based multiple health behaviour change intervention for reducing increases in the six major behavioural risk factors for chronic disease: physical inactivity, poor diet, excessive recreational screen time, poor sleep, and use of alcohol and tobacco. It comprises six online video modules during health education class and a smartphone app. Comparison of Health4Life and usual health education with respect to their impact on changes in twelve secondary outcomes related to the six behavioural risk factors, assessed in surveys at baseline, immediately after the intervention, and 12 and 24 months after the intervention: binge drinking, discretionary food consumption risk, inadequate fruit and vegetable intake, difficulty falling asleep, and light physical activity frequency (categorical); tobacco smoking frequency, alcohol drinking frequency, alcohol-related harm, daytime sleepiness, and time spent watching television and using electronic devices (continuous). A total of 6640 year 7 students completed the baseline survey (Health4Life: 3610; control: 3030); 6454 (97.2%) completed at least one follow-up survey, 5698 (85.8%) two or more follow-up surveys. Health4Life was not statistically more effective than usual school health education for influencing changes in any of the twelve outcomes over 24 months; for example: fruit intake inadequate: odds ratio [OR], 1.08 (95% confidence interval [CI], 0.57-2.05); vegetable intake inadequate: OR, 0.97 (95% CI, 0.64-1.47); increased light physical activity: OR, 1.00 (95% CI, 0.72-1.38); tobacco use frequency: relative difference, 0.03 (95% CI, -0.58 to 0.64) days per 30 days; alcohol use frequency: relative difference, -0.34 (95% CI, -1.16 to 0.49) days per 30 days; device use time: relative difference, -0.07 (95% CI, -0.29 to 0.16) hours per day. Health4Life was not more effective than usual school year 7 health education for modifying adolescent risk factors for chronic disease. Future e-health multiple health behaviour change intervention research should examine the timing and length of the intervention, as well as increasing the number of engagement strategies (eg, goal setting) during the intervention. Australian New Zealand Clinical Trials Registry: ACTRN12619000431123 (prospective).

Prevalence and correlates of psychoactive substance use in domestic and foreign university students

IntroductionUse of psychoactive substances is a risk factor for mental health. Studying the peculiarities of using psychoactive substances by university students is extremely important for organizing preventive health careObjectivesTo specify the frequency of smoking and alcohol drinking, as well as the peculiarities of the correlational interconnections, in domestic and foreign university studentsMethodsThe survey covered 546 undergraduate domestic and foreign university students of both genders and different religious backgrounds. As a tool, we used the Sociocultural Health Questionnaire (E. Nikolaev)ResultsIt has been revealed that domestic students smoke cigarettes and hookahs surely more often (p=.01) than foreign students (30.49% vs 19.08%). It is obvious that they also more often (p=.01) use electronic cigarettes or vaping drugs (25.24% vs 12.86%) and alcohol (54.42% vs 9.96%). Students in both groups denied using other psychoactive substances. Foreign students reveal positive correlational interconnections between smoking and alcohol drinking (r=.44), while there is no evidence of such interconnections in domestic students. Both groups show valid interconnections between the frequency of smoking and the level of stress (r=.15 и r=.17 correspondingly), the frequency of smoking and monthly financial expenses (r=.21 и r=.22 correspondingly). With domestic students, vaping negatively correlates with exercising in gyms (r=-.12), with foreign students it directly correlates with bodybuilding supplements consumption (r=.15). Those foreign students who drink alcohol more often point to the necessity of having a psychologist in the university (r=.13).ConclusionsThe revealed general and specific factors associated with domestic and foreign students’ use of psychoactive substances call for the necessity of developing culturally differentiated preventive programsDisclosure of InterestNone Declared

Estimating the prevalence and clinical significance of chronic obstructive pulmonary disease-obstructive sleep apnea overlap in South Korea

IntroductionConcurrent obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are referred to as COPD-OSA overlap. We investigated the prevalence and clinical significance of COPD-OSA overlap in the general population of South Korea. MethodsData were obtained from the 2019 Korea National Health and Nutrition Examination Survey. Participants ≥40 years of age with complete STOP-Bang questionnaire and spirometry data were included. OSA was presumed in individuals with a STOP-Bang score of ≥3. COPD was determined using forced expiratory volume at 1 s/forced vital capacity <0.7. Participants were classified on the basis of the STOP-Bang score and spirometry findings. Clinical characteristics, comorbidities, and quality of life (using the EuroQoL 5-dimension instrument) were compared between the overlap group and COPD-alone or OSA-alone groups. ResultsAmong the 3157 participants, 6.9 % demonstrated COPD-OSA overlap. Individuals with OSA alone and COPD alone were 31.8 % and 5.2 %, respectively. The overlap group included more males, ever smokers, and frequent alcohol drinkers than the COPD- or OSA-alone groups. The overlap group had more diagnoses of hypertension, diabetes, and stroke than the COPD-alone group. The risk of anxiety/depression was approximately 2.5 times higher in the overlap group than in the COPD-alone group. COPD-OSA overlap was a significant risk factor for anxiety/depression after adjusting for age, sex, household income, and education levels. ConclusionCOPD-OSA overlap is not rare within the general population of South Korea. Patients with overlap showed more comorbidities and higher levels of anxiety/depression than those in the COPD-alone group.

Air pollution, alcohol consumption, and the risk of elevated liver enzyme levels: a cross-sectional study in the UK Biobank.

Evidences on the association between exposure to air pollution and liver enzymes was scarce in low pollution area. We aimed to investigate the association between air pollution and liver enzyme levels and further explore whether alcohol intake influence this association. This cross-sectional study included 425,773 participants aged 37 to 73years from the UK Biobank. Land Use Regression was applied to assess levels of PM2.5, PM10, NO2, and NOx. Levels of liver enzymes including AST, ALT, GGT, and ALP were determined by enzymatic rate method. Long-term low-level exposure to PM2.5 (per 5-μg/m3 increase) was significantly associated with AST (0.596% increase, 95% CI, 0.414 to 0.778%), ALT (0.311% increase, 0.031 to 0.593%), and GGT (1.552% increase, 1.172 to 1.933%); The results were similar for PM10; NOX and NO2 were only significantly correlated with AST and GGT Significant modification effects by alcohol consumption were found (P-interaction < 0.05). The effects of pollutants on AST, ALT, and GGT levels gradually increased along with the weekly alcohol drinking frequency. In conclusion, long-term low-level air pollutants exposure was associated with elevated liver enzyme levels. And alcohol intake may exacerbate the effect of air pollution on liver enzymes.

Evaluating the interaction between 3'aQTL and alcohol consumption/smoking on anxiety and depression: 3'aQTL-by-environment interaction study in UK Biobank cohort

BackgroundSmoking and alcohol consumption were associated with the development of depression and anxiety. 3′UTR APA quantitative trait loci (3'aQTLs) have been associated with multiple health states and conditions. Our aim is to evaluate the interactive effects of 3'aQTLs-alcohol consumption/tobacco smoking on the risk of anxiety and depression. MethodsThe 3'aQTL data of 13 brain regions were extracted from the large-scale 3'aQTL atlas. The phenotype data (frequency of cigarette smoking and alcohol drinking, anxiety score, self-reported anxiety, depression score and self-reported depression) of 90,399–103,011 adults aged 40–69 years living in the UK and contributing to the UK Biobank during 2006–2010, were obtained from the UK Biobank cohort. The frequency of cigarette smoking and alcohol drinking of each subject were defined by the amount of smoking and alcohol drinking of self-reported, respectively. The continuous alcohol consumption/smoking terms were further categorized in tertiles. 3'aQTL-by-environmental interaction analysis was then performed to evaluate the associations of gene-smoking/alcohol consumption interactions with anxiety and depression using generalized linear model (GLM) of PLINK 2.0 with an additive mode of inheritance. Furthermore, GLM was also used to explore the relationship between alcohol consumption/smoking with hazard of anxiety/depression stratified by allele for the significant genotyped SNPs that modified the alcohol consumption/smoking-anxiety/depression association. ResultsThe interaction analysis identified several candidate 3'aQTLs-alcohol consumption interactions, such as rs7602638 located in PPP3R1 (β = 0.08, P = 6.50 × 10−6) for anxiety score; rs10925518 located in RYR2 (OR = 0.95, P = 3.06 × 10−5) for self-reported depression. Interestingly, we also observed that the interactions between TMOD1 (β = 0.18, P = 3.30 × 10−8 for anxiety score; β = 0.17, P = 1.42 × 10−6 for depression score), ZNF407 (β = 0.17, P = 2.11 × 10−6 for anxiety score; β = 0.15, P = 4.26 × 10−5 for depression score) and alcohol consumption was not only associated with anxiety, but related to depression. Besides, we found that relationship between alcohol consumption and hazard of anxiety/depression was significantly different for different SNPs genotypes, such as rs34505550 in TMOD1 (AA: OR = 1.03, P = 1.79 × 10−6; AG: OR = 1.00, P = 0.94; GG: OR = 1.00, P = 0.21) for self-reported anxiety. LimitationsThe identified 3'aQTLs-alcohol consumption/smoking interactions were associated with depression and anxiety, and its potential biological mechanisms need to be further revealed. ConclusionsOur study identified important interactions between candidate 3'aQTL and alcohol consumption/smoking on depression and anxiety, and found that the 3'aQTL may modify the associations between consumption/smoking with depression and anxiety. These findings may help to further explore the pathogenesis of depression and anxiety.

Development and validation of a model for measuring alcohol consumption from transdermal alcohol content data among college students.

Transdermal alcohol content (TAC) data collected by wearable alcohol monitors could potentially contribute to alcohol research, but raw data from the devices are challenging to interpret. We aimed to develop and validate a model using TAC data to detect alcohol drinking. We used a model development and validation study design. Indiana, USA PARTICIPANTS: In March to April 2021, we enrolled 84 college students who reported drinking at least once a week (median age = 20 years, 73% white, 70% female). We observed participants' alcohol drinking behavior for 1week. Participants wore BACtrack Skyn monitors (TAC data), provided self-reported drinking start times in real time (smartphone app) and completed daily surveys about their prior day of drinking. We developed a model using signal filtering, peak detection algorithm, regression and hyperparameter optimization. The input was TAC and outputs were alcohol drinking frequency, start time and magnitude. We validated the model using daily surveys (internal validation) and data collected from college students in 2019 (external validation). Participants (N = 84) self-reported 213 drinking events. Monitors collected 10915 hours of TAC. In internal validation, the model had a sensitivity of 70.9% (95% CI = 64.1%-77.0%) and a specificity of 73.9% (68.9%-78.5%) in detecting drinking events. The median absolute time difference between self-reported and model-detected drinking start times was 59 min. Mean absolute error (MAE) for the reported and detected number of drinks was 2.8 drinks. In an exploratory external validation among five participants, number of drinking events, sensitivity, specificity, median time difference and MAE were 15%, 67%, 100%, 45 minutes and 0.9 drinks, respectively. Our model's output was correlated with breath alcohol concentration data (Spearman's correlation [95% CI] = 0.88 [0.77, 0.94]). This study, the largest of its kind to date, developed and validated a model for detecting alcohol drinking using transdermal alcohol content data collected with a new generation of alcohol monitors. The model and its source code are available as Supporting Information (https://osf.io/xngbk).

MAIN PSYCHOLOGICAL AND CHARACTEROLOGICAL FEATURES OF FORCED MIGRANTS: THE THEORETICAL AND PRACTICAL EXPERIENCE

The article examines the psychological characteristics of young people who drink alcohol, investigates the reasons for it and intensity of alcohol consumption. The propensity of young people to various addictions (addictive behaviour) and its connection with people's impulsivity are analysed. Ukrainian youth who have experience in alcohol drinking usually tried it firstly in adolescence. At the same time, the respondents most often did not mention problems with alcohol in their families, but a third of them recorded such problems, and almost half of the respondents noted that they had experienced physical or psychological violence from a drunken relative. Among the reasons for alcohol drinking, the following were predominant: as a way to distract from problems, improve mood, achieve courage or solve internal problems. Among young people, the strongest addictions were addictions to a healthy lifestyle, television, food or work. Alcohol, romantic relations, medicals, smoking, interpersonal relations and computer usage (internet, social networks) as types of addictions were at an average level. The least pronounced were religious, gambling and drug addictions. There were gender differences in susceptibility to addictions (addictive behaviour). Boys, compared to girls, had higher propensity to romantic relations, drugs and interpersonal relationships as addictions and lower propensity to addiction to medical substances. Peculiarities of personal impulsivity, its links with alcohol consumption were studied. Impulse control disorder influenced on youth's propensity to drinking, increasing alcohol drinking frequency. People with higher impulsivity, who were more prone to imbalance manifestations and more strongly influenced by external factors, were more vulnerable to the risk of developing alcohol and food addictions, addictions to a healthy lifestyle, smoking or interpersonal relationships.

Reported Cases of Alcohol Consumption and Poisoning for the Years 2015 to 2022 in Hail, Saudi Arabia.

This study aimed to determine the pattern of alcohol consumption and its poisoning among the Saudi population in the city of Hail, KSA. Data from a retrospective cohort were collected qualitatively at King Khalid Hospital (KKH) and Hail General Hospital (HGH), covering 550 participants from 2015 to 2022. Two groups were formed comprising patients admitted to the emergency room (ER) and community members; their ages ranged from 19 to 75 years. Group 1 contained 400 participants, of which 250 were patients (244 males, six females) who came to the (ER) with a suspected alcohol overdose or poisoning, and 150 were patients (128 males and 22 females) who were discharged from the (ER) with minimal complaints because of their drinking. Group 2 comprised 150 participants (128 males, 22 females) who were community members, who were surveyed using a questionnaire or interview. In Group 1, 30% of patients reported an altered state of consciousness as a major complaint, 28.8% of patients exhibited abnormal liver function tests (LFTs), 27% had abnormal renal function tests (RFT) with decreased glomerular filtration rates (GFR) and elevated levels of urea and creatinine or low levels of electrolytes or calcium, and 35.6% patients showed elevated levels of pancreatic enzymes. One death was reported due to high alcohol consumption. In Group 2, the community participants reported that they started drinking alcohol due to the influence of other people (29%), stress (11%), depression (10.8%), curiosity (4.4%), and boredom (4%). In addition, 77% of participants were frequent alcohol drinkers and 20% consumed it daily. Further, 68.7% claimed to drink alcohol for more than one hour at a time, while 83.3% experienced blackouts and 70% had problems related to their liver. Moreover, 72.7% of the participants ended up in the hospital and 34.6% suffered from multiple chronic diseases. It is concluded that social influences and stress contributed to the initiation of alcohol use. Despite data gaps, the findings of this study provide a practical understanding of alcohol consumption among the Saudi population and guidance for policymakers.

Risk factors for natural menopause before the age of 45: evidence from two British population-based birth cohort studies

BackgroundMenopause that occurs before the age of 45 and is not medically induced (referred to here as ‘early natural menopause’) affects around one in 10 women and has serious health consequences. These consequences include increased risk of all-cause mortality, cardiovascular disease, osteoporosis, and type 2 diabetes.MethodsWe investigate risk factors for the onset of natural menopause before the age of 45 in two population-based prospective cohort studies in Britain: the 1958 cohort following 8959 women and the 1970 cohort following 8655 women. These studies follow women from birth to adulthood, and we use harmonized data on birth and early life characteristics, reproductive health, health behaviour, and socioeconomic characteristics for 6805 women who were pre-menopausal, peri-menopausal or had undergone natural menopause. Of these 6805 women, 3614 participated in the 1958 cohort (of which 368 had early menopause) and 3191 participated in the 1970 cohort (of which 206 had early menopause). Taking a life course approach, we focus on three distinct life stages - birth/early life, childhood, and early adulthood - to understand when risk factors are most harmful. Respecting the temporal sequence of exposures, we use a series of multivariable logistic regression models to estimate associations between early menopause and each potential risk factor adjusted for confounders.ResultsWe find that early menopause is influenced by circumstances at birth. Women born in lower social class families, whose mother smoked during the pregnancy or who were breastfed 1 month or less were more likely to undergo early menopause. Early menopause is also associated with poorer cognitive ability and smoking in childhood. Adult health behaviour also matters. Smoking is positively correlated with early menopause, while regular exercise and moderate frequency of alcohol drinking in women’s early thirties are associated with reduced risk of early menopause. The occurrence of gynaecological problems by women’s early thirties is also linked to early menopause.ConclusionsWe demonstrate that characteristics at different periods of life are associated with early menopause. Some of these associations relate to modifiable behaviours and thus the risks of early menopause and the adverse health outcomes associated with it may be preventable.

Complications and risk factors after digital subtraction angiography: 1-year single-center study.

Digital subtraction angiography (DSA) is an imaging technique used to diagnose and confirm abnormal lesions of cerebral blood vessels in various situations. Several complications such as cerebral infarction, contrast-induced allergy, and angio-site hematoma or infection can occur after DSA. We investigated complication rates and risk factors related to DSA. All patients who underwent DSA at Incheon St. Mary's Hospital from January to December 2021 were included. Those who underwent emergency DSA due to stroke or who underwent endovascular surgery within 1 week after DSA were excluded. Complications that occurred within 1 week after DSA were included in the study and was classified into three categories (neurologic complications, contrast-induced allergy, and wound complications). The mean age was 57.7±13.2 years old and the female was dominant at 63.9%. The overall complication rate was 5% (n=20/407). Regarding neurologic complications, the presence of malignancy (p<0.01), and a longer procedure time (>15 minutes, p=0.04) were statistically significant factors. Contrast-induced allergy did not show any statistically significant difference in any parameter. The wound complication rate was higher in men (p=0.02), trans-femoral approach (p=0.02), frequent alcohol drinkers (p=0.04), those taking anticoagulants (p=0.03), and longer procedure time (>15 minutes, p<0.01). DSA is an invasive diagnostic modality and can cause several complications. Patients with cancer should be more careful about the occurrence of cerebral infarction, and men taking anticoagulants or drinking frequently should be more careful about the occurrence of angio-site hematomas.

The impact of prolonged exposure to air pollution on the incidence of chronic non-communicable disease based on a cohort in Tianjin

Evidence on the associations of prolonged ambient pollutants exposure with chronic non-communicable diseases among middle-aged and elderly residents is still limited. This prospective cohort study intends to investigate the long-term effects of ambient pollution on hypertension and diabetes incidence among relatively older residents in China. Individual particulate matter exposure levels were estimated by satellite-based model. Individual gaseous pollutants exposure levels were estimated by Inverse Distance Weighted model. A Cox regression model was employed to assess the risks of hypertension and diabetes morbidity linked to air pollutants exposures. The cross-product term of ambient pollutants exposure and covariates was further added into the regression model to test whether covariates would modify these air pollution-morbidity associations. During the period from 2014 to 2018, a total of 97,982 subjects completed follow-up. 12,371 incidents of hypertension and 2034 of diabetes occurred. In the multi-covariates model, the hazard ratios (HR) and 95% confidence interval (CI) were 1.49 (1.45–1.52), 1.28 (1.26–1.30), 1.17 (1.15–1.18), 1.21 (1.17–1.25) and 1.33 (1.31–1.35) for hypertension morbidity per 10 μg/m3 increment in PM1, PM2.5, PM10, NO2 and SO2, respectively. For diabetes onsets, the HR (95% CI) were 1.17 (1.11–1.23), 1.09 (1.04–1.13), 1.06 (1.02–1.09), 1.02 (0.95–1.10), and 1.24 (1.19–1.29), respectively. In addition, for hypertension analyses, the effect estimates were more pronounced in the participants with age <60 years old, BMI ≥24 kg/m2, and frequent alcohol drinking. These findings provided the evidence on elevated risks of morbidity of hypertension and diabetes associated with prolonged ambient pollutants exposure at relatively high levels.

개인별 목표 설정과 스마트폰 기반 영양상담이 과체중 및 비만 시내버스 운전자의 식습관 개선과 체중감소에 미치는 효과

Background/Objectives: This study investigates the impact of personalized goal setting and smartphone-based nutrition counseling on dietary habit improvement and weight loss among city bus drivers with overweight and obesity. Methods: The intervention program was conducted for 52 city bus drivers with overweight and obesity who agreed to participate in the program. Before the program, three specific action goals for behavior modification, including two dietary goals and one activity goal, were individually established, and a goal checklist and a smartwatch were provided to monitor goal attainment. Smartphone-based nutrition counseling using Kakao Talk messenger by a dietitian was conducted for six weeks. Each participant sent the checklist and the smartwatch record to the dietitian once a week, and the dietitian provided feedback through messages. Health habits, dietary habits, food consumption, and anthropometry were measured before and after the intervention. Results: After the intervention, the frequency of alcohol drinking significantly decreased, physical activity increased, and perceived health status improved; the consumption frequencies of multi-grain rice and milk/dairy products significantly increased; and the consumption frequencies of instant noodles, snacks, late-night meals, sweet- and salty-foods decreased significantly compared to those before the program. In addition, after six weeks, the average weight, body mass index, body fat mass, percent body fat, and waist circumference significantly decreased. Most participants (94.2%) were satisfied with nutrition counseling, and 88.5% and 75.0% of participants answered that the intervention program was helpful in improving their dietary habits and in managing their body weight, respectively. Conclusion/Implications: Despite the short intervention period of six weeks, positive changes in health habits, dietary habits, and weight loss were observed. Personalized goal setting and smartphone-based nutrition counseling is considered a good model for dietary habit improvement and weight loss for time-limited workers, such as bus drivers, who have difficulty in making time for nutrition intervention.

Skipping Breakfast and Incidence of Frequent Alcohol Drinking in University Students in Japan: A Retrospective Cohort Study.

Frequency of alcohol drinking is a potential predictor of binge drinking of alcohol, a serious social problem for university students. Although previous studies have identified skipping breakfast as a predictor of various health-compromising behaviors and cardiometabolic diseases, few studies have assessed the association between skipping breakfast and the incidence of frequent alcohol drinking. This retrospective cohort study included 17,380 male and 8799 female university students aged 18–22 years admitted to Osaka universities between 2004 and 2015. The association between breakfast frequency (eating every day, skipping occasionally, and skipping often/usually) and the incidence of frequent alcohol drinking, defined as drinking ≥4 days/week, was assessed using multivariable-adjusted Cox proportional hazards models. During the median observational period of 3.0 years, 878 (5.1%) men and 190 (2.2%) women engaged in frequent alcohol drinking. Skipping breakfast was significantly associated with the incidence of frequent alcohol drinking (adjusted hazard ratios [95% confidence interval] of eating every day, skipping occasionally, and skipping often/usually: 1.00 [reference], 1.02 [0.84–1.25], and 1.48 [1.17–1.88] in men; 1.00 [reference], 1.60 [1.03–2.49], and 3.14 [1.88–5.24] in women, respectively). University students who skipped breakfast were at a higher risk of frequent alcohol drinking than those who ate breakfast every day.

Parenting styles in relation to childhood obesity, smoking and drinking: A gene-environment interaction study.

The present study assessed gene-environment interactions linking maternal parenting styles to childhood obesity and alcohol and tobacco use. Data were retrieved from the first wave of the German Twin Family Panel. Participants comprised three birth cohorts, aged 5, 11 and 17 years, with approximately 500 pairs of same-sex monozygotic twins and 500 pairs of same-sex dizygotic twins per cohort. Self-reported parenting styles were measured in five dimensions: emotional warmth, psychological control, negative communication, monitoring and inconsistent parenting. Outcome variables included children's body mass index z-score (BMIz) and smoking and alcohol drinking frequency. Gene-environment interaction models were used to assess how parenting styles might moderate genetic and environmental influences on BMIz and smoking and drinking behaviours. A positive interaction of genetic effects with psychological control was found for BMIz at age 5 years, indicating that genetic influences on BMIz increased with psychological control. No interaction effect was found for BMIz at ages 11 and 17 years. Regarding adolescent smoking, positive interaction between genetic effects and negative communication was found, indicating that genetic influences on smoking increased with negative communication. There was no significant moderating effect of parenting styles on adolescent drinking. The present study found preliminary evidence indicating that parenting styles moderated genetic and environmental impacts on body weight status and smoking. Moderation effects of parenting on BMIz were observed only at a very young age. The moderating effects of parenting influenced adolescent smoking but not drinking.

Parental Effects on Obesity, Smoking, and Drinking in Children and Adolescents: A Twin Study

PurposeParenting style has been associated with children’s weight-related outcomes and health behaviors, but this relationship may be confounded by genetic influences. Using a twin design to better control for genetics and shared home environments, this study aimed to estimate the longitudinal parental effects on obesity, smoking, and drinking in children and adolescents. MethodsData were retrieved from the first two waves of the German Twin Family Panel. A total of 631 pairs of same-sex monozygotic twins were analyzed, including three birth cohorts aged 5, 11, and 17 years. Self-reported parenting styles were measured in five dimensions: emotional warmth, psychological control, negative communication, monitoring, and inconsistent parenting. Outcome variables included children’s body mass index z-score (BMIz) and smoking and alcohol drinking frequency. The differencing method was used to examine the relationship between within-monozygotic pair differences in parenting styles and health outcomes, controlling for differences at baseline, genetic influences, and other shared characteristics between twins. ResultsControlling for genetics, shared environmental effects, and body weight status at baseline, the twin who received harsher parenting in communication had lower BMI than their cotwin. Subgroup analyses found that negative communication had a stronger impact on the youngest cohort and female twins. Paternal parenting differentially relates to child weight compared to maternal parenting. No concurrent and long-lasting effects of paternal parenting on smoking and drinking were found. DiscussionThe twin study design is a unique epidemiological tool to measure the contribution of genetics as opposed to the environment, to a given health trait. This study found that negative communication was associated with lower BMI in German twin families. However, it failed to identify strong evidence for the causal link between other parenting dimensions and child’s weight status and alcohol and tobacco use. More twin studies with objective measurements are warranted to understand the critical role of parenting, especially family communication, in predicting children’s BMIs and their health behaviors across cultures.