Background: In clinical practice, patients' sleep is disrupted by medical professionals' care or evaluations both at night and during the day. Multiple factors contribute to this sleep disruption resulting in poor clinical outcomes. Aims: This study aims to determine the quality of sleep perceived by patients admitted to various hospital settings, as well as the factors affecting sleep quality. Settings and Design: Descriptive explorative design involving purposive convenient sampling of 90 hospitalized admitted at King Khalid General Hospital, Al Majmaah, and General Hospital, Zulfi. Methodology: St. Mary's Hospital Sleep Questionnaire used to assess patients' sleep and sleep-disturbing scale. Statistical Analysis Used: The Chi-square test was used to compare the different parameters related to sleep. Results: Subjective conclusions suggested that 38 (26.4%) patients slept lightly, 67 (46.5%) were moderately satisfied with their last night's sleep, and only 9 (6.3%) were mildly dissatisfied. Continuous light, uncomfortable Pillow, strange fragrances (P = 0.004), hearing frequent sound (P = 0.018), telephone (P = 0.046), and machine alarms (P = 0.006) were the elements impacting sleep pattern connected to the patient themselves. Tubings, monitor leads, pain, and fear of death all significantly influenced sleep pattern. Many of the healthcare workers' behaviors such as awakening by doctors and nurses (χ 2 = 13.08, P = 0.02), making loud noise (χ 2 = 15.85, P = 0.007), assessing vitals (χ 2 = 12.90, P = 0.02), hygiene care (χ 2 = 5.24, P = 0.14), feeding (χ 2 = 9.82, P = 0.09), tubing and drain (χ 2 = 17.92, P < 0.002), and suctioning (χ 2 = 21.30, P = 0.0001) had significant influence on sleep pattern. Conclusion: Based on the results, nurses can minimize the factors that cause sleep interference in hospitalized patients and avoid the possible negative effects caused by sleep deprivation.
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