An adaptive anti-saturation robust finite-time control algorithm (AARFTC) is designed for flexible air-breathing hypersonic vehicle (FAHV) under actuator saturations. Firstly, an adaptive fixed-time anti-saturation compensator (AFAC) is presented to drive system to faster leave the saturated region Compared to traditional anti-saturation compensators, the auxiliary variable of AFAC is able to realize faster and more accurate convergence when saturation disappears, which avoids the influence on convergent characteristics of tracking error. In addition, the novel adaptive law in AFAC can further shorten the duration of saturation and improve the convergent speed of tracking error via adjusting gain in AFAC according to saturation of actuator. Then, dynamic inversion control is combined with AFAC to establish anti-saturation controller for velocity subsystem. Secondly, differentiator-based backstepping control is combined with AFAC for height subsystem. Two recursive fixed settling time differentiators are utilized to approximate derivatives of virtual control signals exactly in fixed time, which avoids the complex computational burden residing in traditional backstepping control and improves convergent accuracy compared to command filtered backstepping control. Meanwhile, AFAC is utilized to suppress the influence of elevator saturation. Ultimately, multiple sets of simulations on FAHV subject to external disturbances, parametric uncertainties and actuator saturations are carried out to show the superiorities of AFAC and AARFTC.