Emissions of air pollutants from livestock houses may raise environmental problems and pose hazards to public health. They can be reduced by scrubbers installed at the air outlets of livestock houses. In this study, three multi-stage scrubbers were evaluated in terms of their effectiveness in reducing emissions of airborne dust, total bacteria, ammonia, and CO2 from pig houses in winter. The three multi-stage scrubbers were one double-stage scrubber (acid stage+ bio-filter), one double-stage scrubber (acid stage + bio-scrubber), and one triple-stage scrubber (water stage + acid stage + bio-filter). Results showed that these scrubbers reduced concentrations of PM10 by 61% to 93%, concentrations of PM2.5 by 47% to 90%, concentrations of airborne total bacteria by 46% to 85%, and concentrations of ammonia by 70% to 100%. Concentrations of CO2 were not affected. Most of the airborne bacteria emitted from the pig houses were larger than 3.3 m (73% to 95%). The multi-stage scrubbers removed 53% to 92% of them, compared with -42% to 20% removal effectiveness of the bacteria in the size range of 0.65 to 3.3 m. The triple-stage scrubber was the most efficient in removing dust and ammonia. Compared to single-stage scrubbers, all three multi-stage scrubbers performed more consistently in reduction of PM10, PM2.5, total bacteria, and ammonia emissions from livestock houses and removed these pollutants more efficiently. It should be noted that all measurements were performed in winter at low ventilation rates, thus at low loadings of the multi-stage scrubbers.