Airborne Aerosol Research Articles

Long-lifespan, biodegradable, self-disinfecting, and gas-sensing electronic mask with a Janus-structured all-natural fiber network for personal healthcare

Conventional disposable surgical masks have become an integral part of our daily lives, however, present a limited filtration efficiency, brief operative lifespan, and inability to degrade naturally, bringing a heavy burden to the environment. Moreover, these masks cannot efficaciously eliminate bacteria, potentially causing secondary and cross infections among users, thereby failing to curb the spread of infectious diseases. Herein, a fire-new, long-lifespan, biodegradable, self-disinfecting, and gas-sensing electronic-mask is nano-engineered with a Janus-structured all-natural fiber network (SA-CPN) constructed from animal-collagen and plant-fibers. SA-CPN demonstrates exceptional filtration performance (99.9%) for PM2.5 and maintains outstanding filtration efficiency after 10 test-cycles or 32 h in high-humidity conditions. SA-CPN exhibits robust antibacterial origins for extended periods, with antibacterial rates of 98.30%, 99.36%, and 98.11% against P aeruginosa, S aureus, and E coli, respectively, and can effectively filter airborne bacterial aerosols. Moreover, SA-CPN achieves real-time detection of ammonia concentrations, effectively identifying ammonia levels in exhaled human breath and external environments, and monitoring the human respiratory rate, potentially identifying underlying health conditions. The directional water vapor transmission capability of SA-CPN improves comfort when wearing. Notably, SA-CPN can fully biodegrade within 5 h under enzyme action. The proposed multifunctional electronic mask, featuring biocompatibility, biodegradability, self-disinfection, and ammonia sensing capabilities, holds significant promise in personal medical protective equipment for health monitoring and disease prevention.

Influence of different cleaning methods on the concentration of airborne endotoxins and microbial aerosols in the oral clinical environment

AimThis study aims to evaluate the effectiveness of various cleaning methods in reducing airborne endotoxin and microbial aerosols during oral cleaning procedures.MethodForty patients undergoing oral cleaning procedures were randomly assigned to one of four groups (n = 10 per group). Group A received strong suction alone; Group B received strong suction combined with an air disinfection machine; Group C received strong suction combined with a dental electric suction machine; Group D received strong suction in conjunction with both an air disinfection machine and a dental electric suction machine. Airborne aerosol concentrations were assessed at four-time points: before treatment, 30 min into treatment, immediately after treatment, and 60 min after treatment ended. Samples were collected at distances of 20 cm, 60 cm, and 1 m from the patient’s oral cavity using the natural sedimentation method. T-test was used to evaluate the difference among tested groups.ResultsAirborne endotoxins and microbial aerosols levels increased significantly during treatment, with the highest levels observed at 20 cm from the patient’s mouth. During treatment, groups with additional cleaning methods (Groups B, C, and D) exhibited higher levels of airborne endotoxins and microbial aerosols compared to Group A (strong suction alone). However, post-treatment analysis revealed that Group D demonstrated the lowest level of airborne endotoxins and microbial aerosols, while Group A exhibited the highest.ConclusionsImplementing effective aerosol management strategies can significantly reduce aerosol dispersion in the oral clinical environment. Continuous monitoring aerosol concentrations and the application of appropriate control measures are essential for minimizing infection risks for both patients and healthcare providers during oral cleaning procedures.

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.

Aerosol transmission remains a major challenge for control of respiratory viruses, particularly those causing recurrent epidemics, like influenza A virus (IAV). These viruses are rarely expelled alone, but instead are embedded in a consortium of microorganisms that populate the respiratory tract. The impact of microbial communities and inter-pathogen interactions upon stability of transmitted viruses is well-characterized for enteric pathogens, but is under-studied in the respiratory niche. Here, we assessed whether the presence of five different species of commensal respiratory bacteria could influence the persistence of IAV within phosphate-buffered saline and artificial saliva droplets deposited on surfaces at typical indoor air humidity, and within airborne aerosol particles. In droplets, presence of individual species or a mixed bacterial community resulted in 10- to 100-fold more infectious IAV remaining after 1 h, due to bacterial-mediated flattening of drying droplets and early efflorescence. Even when no efflorescence occurred at high humidity or the bacteria-induced changes in droplet morphology were abolished by aerosolization instead of deposition on a well plate, the bacteria remained protective. Staphylococcus aureus and Streptococcus pneumoniae were the most stabilizing compared to other commensals at equivalent density, indicating the composition of an individual's respiratory microbiota is a previously unconsidered factor influencing expelled virus persistence.IMPORTANCEIt is known that respiratory infections such as coronavirus disease 2019 and influenza are transmitted by release of virus-containing aerosols and larger droplets by an infected host. The survival time of viruses expelled into the environment can vary depending on temperature, room air humidity, UV exposure, air composition, and suspending fluid. However, few studies consider the fact that respiratory viruses are not alone in the respiratory tract-we are constantly colonized by a plethora of bacteria in our noses, mouth, and lower respiratory system. In the gut, enteric viruses are known to be stabilized against inactivation and environmental decay by gut bacteria. Despite the presence of a similarly complex bacterial microbiota in the respiratory tract, few studies have investigated whether viral stabilization could occur in this niche. Here, we address this question by investigating influenza A virus stabilization by a range of commensal bacteria in systems representing respiratory aerosols and droplets.

Characterization of the airborne aerosol inlet and transport system used during the A-LIFE aircraft field experiment

Abstract. Atmospheric aerosol particles have a profound impact on Earth's climate by scattering and absorbing solar and terrestrial radiation and by impacting the properties of clouds. Research aircraft such as the Deutsches Zentrum für Luft- und Raumfahrt e.V. (DLR) Falcon are widely used to study aerosol particles in the troposphere and lower stratosphere. However, transporting a representative sample to the instrumentation inside the aircraft remains a challenge due to high airspeeds and changing ambient conditions. In particular, for high-quality coarse-mode aerosol measurements, knowledge about losses or enhancements in the aerosol sampling system is crucial. In this study, the sampling efficiency of the aerosol inlet aboard the Falcon research aircraft is characterized for the first time with state-of-the art in situ measurements including sizing instruments operated behind the Falcon aerosol inlet and mounted at the aircraft wing not affected by the aerosol inlet. Sampling efficiencies were derived for different true airspeed ranges by comparing the in-cabin and ”full”-size-range particle number size distributions during 174 flight sequences with a major contribution of mineral dust particles during the ”Absorbing aerosol layers in a changing climate: aging, lifetime and dynamics” project (A-LIFE). Additionally, experimentally derived Stokes numbers were used to calculate the cutoff diameter of the aerosol sampling system for different particle densities as a function of true airspeed. As expected, the results show that the velocity of the research aircraft has a major impact on the sampling of coarse-mode aerosol particles with in-cabin instruments. For true airspeeds up to about 190 m s−1, aerosol particles larger than about 1 µm are depleted in the sampling system of the Falcon during the A-LIFE project. In contrast, for true airspeeds higher than 190 m s−1, an enhancement of particles up to a diameter of 4 µm is observed. For even larger particles, the enhancement effect at the inlet is still present, but inertial and gravitational particle losses in the transport system get more and more pronounced, which leads to a decreasing overall sampling efficiency. In summary, aerosol particles are either depleted or enhanced in the Falcon aerosol inlet, whereas transport in sampling lines always leads to a loss of particles. Here, we have considered both effects and determined the cutoff diameter for the A-LIFE transport system (i.e., the sampling lines only), the cutoff diameter of the Falcon aerosol inlet (i.e., the effect of the inlet only), and the combined effect of the inlet and sampling lines.

Radioactivity of the atmospheric aerosols detected by CTBTO stations in Africa following the accident at the Fukushima Daiichi nuclear power plant

Radionuclides from the reactor accident Fukushima Daiichi nuclear power plant were observed in the airborne aerosols at CTBT International Monitoring System (IMS) stations (MRP43, CMP13) in Africa. The maximum activity concentrations in the air measured in Mauritania were 186.44 10−6 Bq.m−3, 264.16 10−6 Bq.m−3 and 1269.94 10−6 Bq.m−3 for 134Cs, 137Cs and 131I respectively, and in Cameroon 16.42 10−6 Bq.m−3, 25.53 10−6 and 37.58 10−6 Bq.m−3 respectively for 134Cs, 137Cs and 131I. The activity ratio of 134Cs/137Cs is almost constant throughout the period of time relevant to this study due to their long half-lives of 30.2 years for 137Cs and 2.06 years for 134Cs. Whereas the 131I/137Cs activity ratio varies in time according to the radioactive decay with a half-live of 8.06 days for 131I and different removal rates of both radionuclides from the atmosphere during transport. The EMAC atmospheric chemistry-general circulation was used to simulate the emission and transport of the isotope 137Cs and map the deposition of the 137Cs deposition over Africa.

Inhalation exposure to nanosized aerosols of disinfectants for the application of continuous releasing sprayers and fogger

ABSTRACT This study aimed to investigate the airborne exposure to aerosols according to the particle size distribution of three different spray types (nano-nozzled spray gun, low-temperature steam spray, and fogger) and compare the concentrations of inhaled aerosols between children and adults. Airborne aerosols released from three products were observed using size-segregated particle measurements, and particle concentrations deposited in the respiratory tracts of adults and children were estimated using multi-path particle dosimetry lung deposition models. All types of sprayers generated the most nanoparticles (~100 nm). Due to their higher respiratory rate than adults, a larger number of particles <1.0 μm deposited in the children’s respiratory tracts was higher. The sequences of the total number of particles in the respiratory regions after spraying nano-nozzled spray gun and fogger were alveolar (AL)>tracheobronchial (TB)>head airway (HA) in adults and AL>HA>TB in children. Meanwhile, the trend of low-temperature steam spray was AL>TB>HA in adults and AL>TB>HA in children.

Sea salt reactivity over the northwest Atlantic: an in-depth look using the airborne ACTIVATE dataset

Abstract. Chloride (Cl−) displacement from sea salt particles is an extensively studied phenomenon with implications for human health, visibility, and the global radiation budget. Past works have investigated Cl− depletion over the northwest Atlantic (NWA); however, an updated, multi-seasonal, and geographically expanded account of sea salt reactivity over the region is needed. This study uses chemically resolved mass concentrations and meteorological data from the airborne Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment (ACTIVATE) to quantify seasonal, spatial, and meteorological trends in Cl− depletion and to explore the importance of quantifying (1) non-sea salt sources of Na+ and (2) mass concentrations of lost Cl− (instead of relative amounts displaced). Lost Cl− mass concentrations are lowest in December–February and March, moderate around Bermuda in June, and highest in May (median losses of 0.04, 0.04, 0.66, and 1.76 µg m−3, respectively), with losses in May that are high enough to potentially accelerate tropospheric oxidation rates. Inorganic acidic species can account for all Cl− depletion in December–February, March, and June near Bermuda but none of the lost Cl− in May, suggesting that organic acids may be of importance for Cl− displacement in certain months. Contributions of dust to Na+ are not important seasonally but may cause relevant overestimates of lost Cl− in smoke and dust plumes. Higher percentages of Cl− depletion often do not correspond to larger mass concentrations of lost Cl−, so it is highly recommended to quantify the latter to place depletion reactions in context with their role in atmospheric oxidation and radiative forcing.

Mitigation of Aerosol and Microbial Concentration in a Weaning Piggery by Spraying Nanobubble Ozone Water with an Ultrasonic Sprayer.

Enhancing biosecurity measures in livestock is an essential prerequisite for producing animal products with the highest levels of safety and quality. In Japan, 70% of the mortalities post-weaning are attributed to respiratory pathogens. The research has shown that microorganisms, including both viruses and bacteria, do not merely float in the air independently. Instead, they spread by adhering to aerosols. Therefore, improving the control of aerosol dissemination becomes a critical strategy for reducing pathogenic loads and boosting the overall efficiency of livestock production. This study focused on reducing concentrations of aerosol particles, airborne microbial concentrations, and airborne mass concentrations by spraying ozone solution with an ultrasonic sprayer. The experiments were conducted at a farm in Fukushima Prefecture, Japan, known for its integrated management system, overseeing a herd of 200 sows. Nanobubble ozone water particles were dispersed using an ultrasonic sprayer, which allowed the particles to remain airborne significantly longer than those dispersed using a standard nozzle, at a rate of 30 mL per weaning pig 49 days old, for a 10 min period. This procedure was followed by a 10 min pause, and the cycle was repeated for 17 days. Measurements included concentrations of airborne bacteria, aerosol mass, and aerosol particles. The findings demonstrated a substantial reduction in airborne microbial concentrations of Escherichia coli and Staphylococcus aureus in the treated area compared to the control, with reductions reaching a peak of 85.7% for E. coli and 69.5% for S. aureus. Aerosol particle sizes ranging from 0.3-0.5 µm, 0.5-1.0 µm, 1.0-2.0 µm, 2.0-5.0 µm, to 5.0-10.0 µm were monitored, with a notable decrease in concentrations among larger particles. The average aerosol mass concentration in the test area was over 50% lower than in the control area.

Estimates of Inhaled and Deposited Doses following Exposure to Humidifier Disinfectant Containing Polyhexamethylene Guanidine (PHMG)

We estimated the inhaled and deposited dose in humans using the International Commission on Radiological Protection (ICRP) and multiple-path particle dosimetry (MPPD) models following exposure to humidifier disinfectant containing polyhexamethylene guanidine (PHMG). The disinfectant has caused at least 1,810 deaths, with an odds ratio of lung injury of 47.3 (95% confidence interval: 6.1–369.7), because of its application in Korea. In this study, the Oxy product, which is regarded as the causative agent of most lung diseases, was sprayed into a cleanroom at normal (6.5 ppm in solution) and worst case (65 ppm in solution) dilutions; the airborne aerosol was monitored with direct reading instruments. Areas of deposition were divided into the head airway, tracheobronchial, and alveolar regions. Four dose scenarios were considered in this study: adults and children in both daily average and sleep conditions. Most PHMG aerosols were smaller than PM1 (96%). Number-based concentration analysis showed that &lt;100 nm nanoparticles comprised 81% and 69% of the aerosol when the 6.5 and 65 ppm solutions were used, respectively. In all scenarios, the number-based deposited dose increased in the order of alveolar, tracheobronchial, and head airway regions; the mass-based deposited dose increased in the order of the head airway, alveolar, and tracheobronchial regions. The deposited dose per unit body weight was higher in children than in adults in terms of both number- and mass-based concentrations. When the humidifier was sprayed, the highest number-based concentration was found at a particle size of 15.4 nm; the highest deposition fraction or dose by PM1 was observed in the pulmonary and head airways in both models.

Mitigating Information Interruptions by COVID-19 Face Masks: A Three-Stage Speech Enhancement Scheme

The coronavirus disease 2019 (COVID-19) preventive measures have resulted in significant lifestyle changes. One of the COVID-19 new normal is the usage of face masks for protection against airborne aerosol which creates distractions and interruptions in voice communication. It has a different influence on speech than the standard concept of noise affecting speech communication. Furthermore, it has varied effects on speech in different frequency bands. To provide a solution to this problem, a three-stage adaptive speech enhancement (SE) scheme is developed in this article. In the first stage, the tunable <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$Q$</tex-math> </inline-formula> -factor wavelet transform (TQWT) features are extracted by properly setting the quality factor values and the number of levels from the input speech signal. In the second stage, the adjustable parameters of the preemphasis filter and modified multiband spectral subtraction (MBSS) are determined using bio-inspired techniques for different masking and signal-to-noise ratio (SNR) conditions. In the third stage, the weights, center values, standard deviation of the Gaussian radial basis functions, and input patterns of the radial basis function neural networks (RBFNNs) are updated to predict the optimized parameters from the input TQWT-based cepstral features (TQCFs). In the end, the performance of the proposed algorithm is compared with the standard SE algorithms using two speech datasets.

Size-classified aerosol-bound heavy metals and their effects on human health risks in industrial and remote areas in Japan

Airborne aerosols were collected in six size classes (PM<0.1, PM0.1–0.5, PM0.5–1, PM1–2.5, PM2.5–10 and PM>10) to investigate aerosol health risks in remote and industrial areas in Japan. We focused on heavy metals and their water-dispersed fractions. The average concentration of heavy metals was 18 ± 25–86 ± 48 ngm−3 for PM<0.1, 46 ± 19–154 ± 80 for PM0.5–1 ngm−3, 98 ± 49–422 ± 186 ngm−3 for PM1–2.5, 321 ± 305–1288 ± 727 ngm−3 for PM2.5–10 and 65 ± 52–914 ± 339 ngm−3 or PM>10, and these concentrations were higher in industrial areas. Heavy metals emitted from domestic anthropogenic sources were added to the long-range transport component of the aerosols. The water-dispersed fraction of heavy metals contained 3.3–40.1% of the total heavy metals in each size class. The relative contribution of Zn and other species (As, Cd, Cr, Ni, Pb, Mn, V and Cu) increased in the water-dispersed fraction. Smaller particles contained greater proportions of the water-dispersed heavy metal fraction. Carcinogenic risk (CR) and the hazard index (HI) were estimated for each size class. The CR of carcinogens was at acceptable levels (<1 ×10−6) for five particle size fractions. The HI values for carcinogens and noncarcinogens were also below acceptable levels (<1) for the same five size fractions. The estimated CR and HI values were dominated by contributions from the inhalation process.

A novel approach for automated rhinoceros beetle control in oil palm replanting: pineapple peel-derived pheromone trap

Oil palm (Elaeis guineensis Jacq) is a crucial plant for Indonesia's economy, serving as a major non-oil foreign exchange earner. A significant pest affecting oil palm cultivation, especially during replanting, is the rhinoceros beetle (Oryctes rhinoceros L.). Attractant pheromones, derived from pineapples, contain volatile compounds that attract insects. This research aims to develop an automated rhinoceros beetle trap equipped with an automatic pheromone spray system utilizing natural peel pineapple extract. The analysis includes tests for fluid density, spray distribution, and normality. The fluid density of the sample closely resembles that of water (1 g/cm³). Spray distribution results indicate particle sizes (60-112 μm) larger than airborne aerosols (0.001-50 μm). Kolmogorov-Smirnov normality tests reveal mostly normal data distribution, with minor deviations. Overall, this trap exhibits promise as an effective solution for rhinoceros beetle control in oil palm cultivation.

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission

SARS-CoV-2 is primarily transmitted through droplets and airborne aerosols, and in order to prevent infection and reduce viral spread vaccines should elicit protective immunity in the airways. The neonatal Fc receptor (FcRn) transfers IgG across epithelial barriers and can enhance mucosal delivery of antigens. Here we explore FcRn-mediated respiratory delivery of SARS-CoV-2 spike (S). A monomeric IgG Fc was fused to a stabilized spike; the resulting S-Fc bound to S-specific antibodies and FcRn. Intranasal immunization of mice with S-Fc and CpG significantly induced antibody responses compared to the vaccination with S alone or PBS. Furthermore, we intranasally immunized mice or hamsters with S-Fc. A significant reduction of virus replication in nasal turbinate, lung, and brain was observed following nasal challenges with SARS-CoV-2 and its variants. Intranasal immunization also significantly reduced viral airborne transmission in hamsters. Nasal IgA, neutralizing antibodies, lung-resident memory T cells, and bone-marrow S-specific plasma cells mediated protection. Hence, FcRn delivers an S-Fc antigen effectively into the airway and induces protection against SARS-CoV-2 infection and transmission.

Cytosponge procedures produce fewer respiratory aerosols and droplets than esophagogastroduodenoscopies.

Esophagogastroduodenoscopies (EGD) are aerosol-generating procedures that may spread respiratory pathogens. We aim to investigate the production of airborne aerosols and droplets during Cytosponge procedures, which are being evaluated in large-scale research studies and National Health Service (NHS)implementation pilots to reduce endoscopy backlogs. We measured 18 Cytosponge and 37 EGD procedures using a particle counter (diameters = 0.3-25μm), taking measurements 10cm from the mouth. Two particle count analyses were performed: whole procedure and event-based. Direct comparison with duration-standardized EGD procedures shows that Cytosponge procedures produce 2.16× reduction (P < 0.001) for aerosols and no significant change for droplets (P =0.332). Event-based analysis shows that particle production is driven by throat spray (aerosols: 138.1× reference, droplets: 16.2×), which is optional, and removal of Cytosponge (aerosols: 14.6×, droplets: 62.6×). Cytosponge burping produces less aerosols than EGD (2.82×, P < 0.05). Cytosponge procedures produce significantly less aerosols and droplets than EGD procedures and thus reduce two potential transmission routes for respiratory viruses.

Generation of Aerosols by Noninvasive Respiratory Support Modalities

Infection control guidelines have historically classified high-flow nasal oxygen and noninvasive ventilation as aerosol-generating procedures that require specialized infection prevention and control measures. To evaluate the current evidence that high-flow nasal oxygen and noninvasive ventilation are associated with pathogen-laden aerosols and aerosol generation. A systematic search of EMBASE and PubMed/MEDLINE up to March 15, 2023, and CINAHL and ClinicalTrials.gov up to August 1, 2023, was performed. Observational and (quasi-)experimental studies of patients or healthy volunteers supported with high-flow nasal oxygen or noninvasive ventilation were selected. Three reviewers were involved in independent study screening, assessment of risk of bias, and data extraction. Data from observational studies were pooled using a random-effects model at both sample and patient levels. Sensitivity analyses were performed to assess the influence of model choice. The main outcomes were the detection of pathogens in air samples and the quantity of aerosol particles. Twenty-four studies were included, of which 12 involved measurements in patients and 15 in healthy volunteers. Five observational studies on SARS-CoV-2 detection in a total of 212 air samples during high-flow nasal oxygen in 152 patients with COVID-19 were pooled for meta-analysis. There was no association between high-flow nasal oxygen and pathogen-laden aerosols (odds ratios for positive samples, 0.73 [95% CI, 0.15-3.55] at the sample level and 0.80 [95% CI, 0.14-4.59] at the patient level). Two studies assessed SARS-CoV-2 detection during noninvasive ventilation (84 air samples from 72 patients). There was no association between noninvasive ventilation and pathogen-laden aerosols (odds ratios for positive samples, 0.38 [95% CI, 0.03-4.63] at the sample level and 0.43 [95% CI, 0.01-27.12] at the patient level). None of the studies in healthy volunteers reported clinically relevant increases in aerosol particle production by high-flow nasal oxygen or noninvasive ventilation. This systematic review and meta-analysis found no association between high-flow nasal oxygen or noninvasive ventilation and increased airborne pathogen detection or aerosol generation. These findings argue against classifying high-flow nasal oxygen or noninvasive ventilation as aerosol-generating procedures or differentiating infection prevention and control practices for patients receiving these modalities.

Mapping the performance of a versatile water-based condensation particle counter (vWCPC) with numerical simulation and experimental study

Abstract. Accurate airborne aerosol instrumentation is required to determine the spatial distribution of ambient aerosol particles, particularly when dealing with the complex vertical profiles and horizontal variations of atmospheric aerosols. A versatile water-based condensation particle counter (vWCPC) has been developed to provide aerosol concentration measurements under various environments with the advantage of reducing the health and safety concerns associated with using butanol or other chemicals as the working fluid. However, the airborne deployment of vWCPCs is relatively limited due to the lack of characterization of vWCPC performance at reduced pressures. Given the complex combinations of operating parameters in vWCPCs, modeling studies have advantages in mapping vWCPC performance. In this work, we thoroughly investigated the performance of a laminar-flow vWCPC using COMSOL Multiphysics® simulation coupled with MATLAB™. We compared it against a modified vWCPC (vWCPC model 3789, TSI, Shoreview, MN, USA). Our simulation determined the performance of particle activation and droplet growth in the vWCPC growth tube, including the supersaturation, Dp,kel,0 (smallest size of particle that can be activated), Dp,kel,50 (particle size activated with 50 % efficiency) profile, and final growth particle size Dd under wide operating temperatures, inlet pressures P (30–101 kPa), and growth tube geometry (diameter D and initiator length Lini). The effect of inlet pressure and conditioner temperature on vWCPC 3789 performance was also examined and compared with laboratory experiments. The COMSOL simulation result showed that increasing the temperature difference (ΔT) between conditioner temperature Tcon and initiator Tini will reduce Dp,kel,0 and the cut-off size Dp,kel,50 of the vWCPC. In addition, lowering the temperature midpoint (Tmid=Tcon+Tini2) increases the supersaturation and slightly decreases the Dp,kel. The droplet size at the end of the growth tube is not significantly dependent on raising or lowering the temperature midpoint but significantly decreases at reduced inlet pressure, which indirectly alters the vWCPC empirical cut-off size. Our study shows that the current simulated growth tube geometry (D=6.3 mm and Lini=30 mm) is an optimized choice for current vWCPC flow and temperature settings. The current simulation can more realistically represent the Dp,kel for 7 nm vWCPC and also achieved good agreement with the 2 nm setting. Using the new simulation approach, we provide an optimized operation setting for the 7 nm setting. This study will guide further vWCPC performance optimization for applications requiring precise particle detection and atmospheric aerosol monitoring.

Development of an airfoil-based passive volumetric air sampling and flow control system for fixed-wing UAS

This study aims to develop a concept of a passive volumetric flow control system for gas sampling applications onboard fixed-wing UAS based on the pressure field around airfoils. The passive flow control system utilizes the aerodynamics of a UAS to create a vacuum pump effect that ensures constant gas sampling, which can be used to facilitate airborne aerosol and gas measurements. The pump effect is achieved by short-circuiting the pressure field’s minima and maxima points around an airfoil through pipes and 3D printed structures that could function both as a pump system and a gas measurement chamber. The design of this structurally integrated functionality brings many advantages for scientific applications, especially onboard small research UAS, which would dispense entirely with complex active pump systems, thus reducing weight and ensuring gas sampling at a constant volumetric flow rate independent of altitude and atmospheric variance. In favor of developing further applications, this paper outlines the development steps of the passive pump concept starting from the theory and numerical modeling of the effect to the implementation on board a fixed-wing UAS. Finally, possible improvements based on numerical models and flight measurements are discussed.

Self-sustaining levitation of droplets above a liquid pool

In this Letter, we report the phenomenon of self-sustaining and long-term (&amp;gt;103 s) levitation of millimeter-sized droplets of a variety of liquids without any external forces. The droplet levitation is enabled by solutocapillary convection in the liquid pool, which occurs due to the surface tension gradient originating from non-uniform distribution of vapor molecules from the droplet at the pool surface. The droplet lifetime can be adjusted by adding the droplet liquid into the pool. The maximum levitation duration is achieved at a concentration that reduces the evaporation rate of the droplets and increases the solutocapillary flow in the pool. Such self-sustaining droplet levitation occurs under ambient conditions and can be used as an effective tool for studying the activity of viruses and microorganisms as they are transferred in airborne aerosols.

Comparison of Aerosol Emissions during Specific Speech Tasks

Recent investigations into the behavior of aerosolized emissions from the oral cavity have shown that particulate emissions do indeed occur during speech. To date, there is little information about the relative contribution of different speech sounds in producing particle emissions in a free field. This study compares airborne aerosol generation in participants producing isolated speech sounds: fricative consonants, plosive consonants, and vowel sounds. Prospective, reversal experimental design, where each participant served as their own control and all participants were exposed to all stimuli. While participants produced isolated speech tasks, a planar beam of laser light, a high-speed camera, and image software calculated the number of particulates detected over time. This study compared airborne aerosols emitted by human participants at a distance of 2.54cm between the laser sheet and the mouth. Statistically significant increases in particulate count over ambient dust distribution for all speech sounds. When collapsed across loudness levels, emitted particles in vowel sounds were statistically greater than consonants, suggesting that mouth opening, as opposed to the place of vocal tract constriction or manner of sound production, might also be influential in the degree to which particulates become aerosolized during speech. The results of this research will inform boundary conditions for computational models of aerosolized particulates during speech.

Numerical Model and System for Prediction and Reduction of Indoor COVID-19 Infection Risk

Airborne aerosol transmission is a significant route of SARS-CoV-2 and other viruses in indoor environments. The developed numerical model assesses the risk of a COVID-19 infection in a room based on the measurements of temperature, relative humidity, CO2 and particle concentration, as well as the number of people and occurrences of speech, coughing, and sneezing obtained through a dedicated low-cost sensor system [1]. As the model operates faster than real-time, it can dynamically feed this information back to the measurement system or building management system, and it can activate an air purifier with filtration and UV-C disinfection when the predicted infection risk is high. This solution enhances energy efficiency as (1) lower ventilation intensity is necessary in the cold season to reach the same safety level and (2) the purifier is activated only if the predicted infection risk is above a certain threshold.The model is integral and takes into account the average values of simulated variables. However, it considers the inhomogeneous vertical distribution of concentration of droplets and aerosol particles. The droplets expelled by a potentially infectious person at a certain height through breathing, speaking, coughing, and sneezing are characterized by the total amount of expelled liquid, droplet size distribution and virus particle concentration. The rate of droplet evaporation depends on the temperature and relative humidity. Droplets are redistributed within the room vertically through turbulent diffusion and gravitational force. If the final droplet diameter is less than 5 mm, these particles are considered airborne and can leave the room only by ventilation, filtration, or by sedimentation on surfaces through Brownian diffusion. As a person in the room inhales these droplets and aerosols, the risk of infection increases as the number of absorbed virions grows, with the probability of infection being 50% when 300 virions have been inhaled.The parameter studies using the model indicate that the coughing and sneezing events greatly increase the probability of infection in the room, therefore the identification of these events is crucial for the applied measurement system. A method for determining the unknown ventilation intensity by measuring the number of people and the CO2 concentration is proposed and tested.