With the sudden outbreak and rapid spread of COVID-19, global economic development and social stability have been seriously affected. The virus mainly spreads infection among people on a large scale through the air. People are gradually focusing on how to use HVAC system, so that it can play a more efficient and positive role in epidemic prevention and control. Consequently, we designed an intelligent purification and disinfection apparatus for air-conditioning units. The apparatus integrates rapid virus detection and high-efficiency disinfection functions. It uses a modular design and different operating modes for different levels of epidemic periods. This apparatus is not only suitable for daily life, but also can meet the prevention and control requirements during the epidemic period, which takes the economy, energy saving, and environmental protection into account.