Air cargo significantly contributes to trade, bridging the gap between production and consumption in a timely and reliable manner. The specific industry is a complex system, participating many players and requiring many documents and actions. Greece’s economic growth is highly dependent on the exportation and import of goods. The current study intends to analyse the Greek air cargo industry, implementing a more holistic approach, identifying the main problems and challenges, and making useful recommendations. In-depth focus group discussion with the participation of twelve (12) experts (n=12) and observation applied to collect the required information. The main findings present the high level of bureaucracy, the lack of cooperation between the partners and the use of technology that caused significant problems in the industry’s performance, while some effective interventions were proposed. The study provides useful insights to the related practitioners, policy-makers and academicians.