Background: In critically ill patients, correct placement of the tip of the enteral feeding tubes in the duodenum is usually controlled by means of X-ray. A direct bedside method without radiation exposure would preferable. Aim: To demonstrate the usefulness of bedside sonographic position control for enteral feeding tubes in critically ill patients. Methods: In 76 patients, position of the tip of the enteral feeding tube was determined by bedside transabdominal ultrasound. Native ultrasound was enhanced by using enteral injection of air bubbles. Correct position was defined as a visible tube within the second or third duodenal portion. Thereafter, plain abdominal radiographs with contrast served as gold standard. Results: To date, a total of 76 examinations were analyzed. In 12 cases, access to the upper abdominal wall was not possible due to open wounds. In another 13 cases, duodenum was not identified and no statement about tube position was made. In 51/76 patients (67%), ultrasound identified the correct position in 48 cases (46 true positive and 2 true negative). In 3 cases, the position was incorrectly diagnosed. The sensitivity and specificity was 96% (95% CI 87-98) and 33% (95% CI 20-48), respectively. Positive predictive value of ultrasound was 94%. Conclusions: If duodenum is accessible and visible by ultrasound, this simple and “new” method is very sensitive and may replace radiological control of the position of the tip of enteral feeding tubes. Background: In critically ill patients, correct placement of the tip of the enteral feeding tubes in the duodenum is usually controlled by means of X-ray. A direct bedside method without radiation exposure would preferable. Aim: To demonstrate the usefulness of bedside sonographic position control for enteral feeding tubes in critically ill patients. Methods: In 76 patients, position of the tip of the enteral feeding tube was determined by bedside transabdominal ultrasound. Native ultrasound was enhanced by using enteral injection of air bubbles. Correct position was defined as a visible tube within the second or third duodenal portion. Thereafter, plain abdominal radiographs with contrast served as gold standard. Results: To date, a total of 76 examinations were analyzed. In 12 cases, access to the upper abdominal wall was not possible due to open wounds. In another 13 cases, duodenum was not identified and no statement about tube position was made. In 51/76 patients (67%), ultrasound identified the correct position in 48 cases (46 true positive and 2 true negative). In 3 cases, the position was incorrectly diagnosed. The sensitivity and specificity was 96% (95% CI 87-98) and 33% (95% CI 20-48), respectively. Positive predictive value of ultrasound was 94%. Conclusions: If duodenum is accessible and visible by ultrasound, this simple and “new” method is very sensitive and may replace radiological control of the position of the tip of enteral feeding tubes.