Age-related Differences In Performance Research Articles

Nonlinear age effects in tactile processing from early childhood to adulthood.

BackgroundTactile processing plays a pivotal role in the early stages of human development; however, little is known about tactile function in young children. An understanding of how tactile processing changes with age from early childhood to adulthood is fundamental in understanding altered tactile experiences in neurodevelopmental disorders, such as autism spectrum disorder.MethodsIn this cross‐sectional study, 142 children and adults aged 3–23 years completed a vibrotactile testing battery consisting of 5 tasks, which rely on different cortical and cognitive mechanisms. The battery was designed to be suitable for testing in young children to investigate how tactile processing changes from early childhood to adulthood.ResultsOur results suggest a pattern of rapid, age‐related changes in tactile processing toward lower discrimination thresholds (lower discrimination thresholds = greater sensitivity) across early childhood, though we acknowledge limitations with cross‐sectional data. Differences in the rate of change across tasks were observed, with tactile performance reaching adult‐like levels at a younger age on some tasks compared to others.ConclusionsWhile it is known that early childhood is a period of profound development including tactile processing, our data provides evidence for subtle differences in the developmental rate of the various underlying cortical, physical, and cognitive processes. Further, we are the first to show the feasibility of vibrotactile testing in early childhood (<6 years). The results of this work provide estimates of age‐related differences in performance, which could have important implications as a reference for investigating altered tactile processing in developmental disorders.

The Impact of Chronic Musculoskeletal Pain on Traditional and Modified Pain Stroop Task Performance in Older Adults

Aging studies that have employed the Stroop Color and Word Test have identified several factors that influence the effect of age on inhibitory control, cognitive facilitation, and selective attention. An understudied factor that may influence, and further qualify, this relationship is chronic musculoskeletal pain. Therefore, the purpose of this study was to determine how chronic musculoskeletal pain impacts traditional and modified pain Stroop performance in older adults with chronic pain. Participants completed a computerized traditional and modified pain Stroop task. A series of mixed ANOVAs were used to compare reaction times, accuracy rates, interference scores, and facilitation scores between ‘Younger Adults without Chronic Pain' (n = 19), ‘Older Adults without Chronic Pain (n = 23), and ‘Older Adults with Chronic Pain' (n = 36) for each Stroop condition. A mediation analysis using the product-of-the-coefficients method with bootstrapping (5,000 samples) was also run to assess the indirect effect of aging on Stroop performance through the mediator of pain severity. (Preacher & Hayes, 2004; Preacher et al., 2007). No differences were found between older adults with and without chronic pain for any Stroop performance measure. On average, the ‘Younger Adults without Chronic Pain' had significantly faster reaction times than both older adult groups for the traditional and modified pain Stroop tasks (p < 0.001). Pain severity partially mediated the relationship between aging and traditional Stroop congruent condition reaction time and fully mediated the relationship between aging and traditional Stroop interference and facilitation. Mild levels of chronic pain were not enough to elicit differences in inhibitory control, cognitive facilitation, or selective attention between older adults with and without chronic pain. Pain severity, however, mediates the relationship between age and traditional Stroop performance, which suggests cognitive declines associated with chronic pain may contribute to age-related differences in Stroop performance. Grant support from NIA grants K01AG048259, R01AG059809, R01AG067757 to YCA; University of Florida Claude D. Pepper Center (P30AG028740) to YCA.

Volume of the posterior hippocampus mediates age-related differences in spatial context memory and is correlated with increased activity in lateral frontal, parietal and occipital regions in healthy aging

Healthy aging is associated with episodic memory decline, particularly in the ability to encode and retrieve object-context associations (context memory). Neuropsychological and neuroimaging studies have highlighted the importance of the medial temporal lobes (MTL) in supporting episodic memory across the lifespan. However, given the functional heterogeneity of the MTL, volumetric declines in distinct regions may impact performance on specific episodic memory tasks, and affect the function of the large-scale neurocognitive networks supporting episodic memory encoding and retrieval. In the current study, we investigated how MTL structure may mediate age-related differences in performance on spatial and temporal context memory tasks, in a sample of 125 healthy adults aged 19–76 years old. Standard T1-weighted MRIs were segmented into the perirhinal, entorhinal and parahippocampal cortices, as well as the anterior and posterior hippocampal subregions. We observed negative linear and quadratic associations between age and volume of the parahippocampal cortex, and anterior and posterior hippocampal subregions. We also found that volume of the posterior hippocampus fully mediated the association between age and spatial, but not temporal context memory performance. Further, we employed a multivariate behavior partial-least-squares analysis to assess how age and regional MTL volumes correlated with brain activity during the encoding and retrieval of spatial context memories. We found that greater activity within lateral prefrontal, parietal, and occipital regions, as well as within the anterior MTL was related to older age and smaller volume of the posterior hippocampus. Our results highlight the heterogeneity of MTL contributions to episodic memory across the lifespan and provide support for the posterior-anterior shift in aging, and scaffolding theory of aging and cognition.

Age-related effects of executive function on takeover performance in automated driving

The development of highly automated vehicles can meet elderly drivers’ mobility needs; however, worse driving performance after a takeover request (TOR) is frequently found, especially regarding non-driving related tasks (NDRTs). This study aims to detect the correlation between takeover performance and underlying cognitive factors comprising a set of higher order cognitive processes including executive functions. Thirty-five young and 35 elderly participants were tested by computerized cognitive tasks and simulated driving tasks to evaluate their executive functions and takeover performance. Performance of n-back tasks, Simon tasks, and task switching were used to evaluate updating, inhibition, and shifting components of executive functions by principal component analysis. The performance of lane changing after TOR was measured using the standard deviation of the steering wheel angle and minimum time-to-collision (TTC). Differences between age groups and NDRT engagement were assessed by two-way mixed analysis of variance. Older participants had significantly lower executive function ability and were less stable and more conservative when engaged in NDRT. Furthermore, a significant correlation between executive function and lateral driving stability was found. These findings highlight the interaction between age-related differences in executive functions and takeover performance; thus, provide implications for designing driver screening tests or human–machine interfaces.

Dissociable oscillatory theta signatures of memory formation in the developing brain

Understanding complex human brain functions is critically informed by studying such functions during development. Here, we addressed a major gap in models of human memory by leveraging rare direct electrophysiological recordings from children and adolescents. Specifically, memory relies on interactions between the medial temporal lobe (MTL) and prefrontal cortex (PFC), and the maturation of these interactions is posited to play a key role in supporting memory development. To understand the nature of MTL-PFC interactions, we examined subdural recordings from MTL and PFC in 21 neurosurgical patients aged 5.9-20.5 years as they performed an established scene memory task. We determined signatures of memory formation by comparing the study of subsequently recognized to forgotten scenes in single trials. Results establish that MTL and PFC interact via two distinct theta mechanisms, an ∼3-Hz oscillation that supports amplitude coupling and slows down with age and an ∼7-Hz oscillation that supports phase coupling and speeds up with age. Slow and fast theta interactions immediately preceding scene onset further explained age-related differences in recognition performance. Last, with additional diffusion imaging data, we linked both functional mechanisms to the structural maturation of the cingulum tract. Our findings establish system-level dynamics of memory formation and suggest that MTL and PFC interact via increasingly dissociable mechanisms as memory improves across development.

Transparency, replicability, and discovery in cognitive aging research: A computational modeling approach.

Healthy aging is associated with deficits in performance on episodic memory tasks. Popular verbal theories of the mechanisms underlying this decrement have primarily focused on inferred changes in associative memory. However, performance on any task is the result of interactions between different neurocognitive mechanisms, such as perceptuomotor, memory, and decision-making processes. As a result, age-related differences in performance could arise from multiple processes, which could lead to incomplete or incorrect conclusions about the sources of aging effects. In addition, standard statistical comparisons of group-level summary statistics, such as mean accuracy, may not provide sufficient information to allow detailed mechanistic explanations of age-related change. We argue that these and other drawbacks of relying exclusively on verbal theories can hamper replicability, transparency, and scientific progress in aging research and psychological science more generally, and that computational modeling is a tool that can address many of these limitations. Computational models make mathematically transparent claims about how latent processes give rise to observed behavior and decompose an individual's performance into model parameters governing hypothesized mechanisms. In this work, we present a short memory task designed for and analyzed with mechanistic model-based approaches. We provide an example of a computational model and fit the model to data from young and older adults with hierarchical Bayesian techniques in order to (a) detect differences in latent cognitive processes between young and older adults (as well as individual participants), (b) quantitatively compare models to assess different processes that could underlie performance, and (c) simulate data to make predictions for future experiments based on model mechanisms. We argue that computational modeling is a powerful tool to examine age differences in latent processes, make theories more transparent, and facilitate discovery in cognitive aging research. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Increase in Volitional Muscle Activation from Childhood to Adulthood: A Systematic Review and Meta-analysis.

ABSTRACTIntroductionChildren’s maximal muscle strength is consistently lower than adults’, even when normalized to body size. Lower volitional muscle activation (VA) in children is often considered one of the main reasons for age-related differences in muscular performance. However, some recent studies have reported similar VA in children and adults, bringing into question whether there is indeed an age-related increase in VA. The purpose of this review was to determine the effect of age on VA during maximal isometric contractions.MethodsLiterature examining VA differences, using twitch interpolation in children (7–14 yr) and adults (16–28 yr), was systematically reviewed. Of the 1915 studies initially identified, 19 data sets were eligible for inclusion in the qualitative analysis and 14 in the quantitative meta-analysis (comprising 207 children and 193 adults).ResultsSignificantly lower VA in children was reported in 9/19 (47%) studies. A random-effects meta-analysis found a strong effect of age on VA, supporting lower VA in children compared with adults (Hedges’ g = 1.55; confidence interval: 0.9–2.13). Moderator analysis included muscle group, sex, children’s age, stimulation number (singlet, multiple), type (electric, magnetic), and location (muscle, nerve), of which only muscle group was significant (P < 0.001). A significant Egger’s regression test and asymmetrical funnel plot suggest that publication bias may be present.ConclusionsOverall, these findings suggest that compared with adults, children activate their motor-unit pool less compared with adults. Moreover, that the degree of VA increase with age may be influenced by the muscle examined (upper vs lower extremity). However, more research is needed to elucidate the influence of this possible factor, as the current review contains limited data from upper body muscles. The developmental mechanism responsible for children’s lower VA requires further research.

Semantic knowledge attenuates age-related differences in event segmentation and episodic memory.

While semantic and episodic memory may be distinct memory systems, their interdependence is substantial. For instance, decades of work have shown that semantic knowledge facilitates episodic memory. Here, we aim to clarify this interactive relationship by determining whether semantic knowledge facilitates the acquisition of new episodic memories, in part, by influencing an encoding mechanism, event segmentation. In the current study, we evaluated the extent to which semantic knowledge shapes how people segment ongoing activity and how such knowledge-related benefits in segmentation affect episodic memory performance. To investigate these effects, we combined data across three studies that had young and older adults segment and remember videos of everyday activities that were either familiar or unfamiliar to their age group. We found age-related differences in event-segmentation ability and memory performance, but only when older adults lacked semantic knowledge. Most importantly, when they had access to relevant semantic knowledge, older adults segmented and remembered information similar to young adults. Our findings indicate that older adults can use semantic knowledge to effectively encode and retrieve everyday information. These effects suggest that future interventions can leverage older adults' intact semantic knowledge to attenuate age-related deficits in event segmentation and episodic long-term memory.

Age-related differences in linear sprint in adolescent female soccer players

BackgroundSeveral studies have observed the contribution of chronological age, biological maturation, and anthropometric characteristics to sprinting performance in young soccer players. Nevertheless, there are no studies that have analysed the contribution of these characteristics to running speed qualities in adolescent female soccer players.ObjectiveThis study investigated age-related differences in sprint performance in adolescent female soccer players. Also, it examined the possible influence of anthropometry [body mass and body mass index (BMI)] and biological maturation [age at peak height velocity (APHV)] in sprint performance.MethodsEighty adolescent female soccer players [under (U) 14, n = 20; U16, n = 37; U18, n = 23] participated in this study. Players were tested for 40 m sprint (each 10 m split times).ResultsPosthoc analysis revealed better performance in all split sprint times of older soccer players (U18 and U16) compared with younger category (F: 3.380 to 6.169; p < 0.05; ES: 0.64 to 1.33). On the contrary in all split sprint times, there were no significant changes between U16 and U18 (p < 0.05; ES: 0.03 to 0.17). ANCOVA revealed differences in all parameters between groups, controlled for APHV (p < 0.05). In contrast, all between-group differences disappeared after body mass and BMI adjustment (p > 0.05). Finally, the results indicate that BMI and body mass were significantly correlated with 40 m sprint (p < 0.05; r: -0.31) and 20 m flying (p < 0.01; r: 0.38), respectively.ConclusionIn the present players’ sample, body mass and BMI had a significant impact on running speed qualities.

Cerebellar Dentate Connectivity across Adulthood: A Large-Scale Resting State Functional Connectivity Investigation.

Cerebellar contributions to behavior in advanced age are of interest and importance, given its role in motor and cognitive performance. There are differences and declines in cerebellar structure in advanced age and cerebellar resting state connectivity is lower. However, the work on this area to date has focused on the cerebellar cortex. The deep cerebellar nuclei provide the primary cerebellar inputs and outputs to the cortex, as well as the spinal and vestibular systems. Dentate networks can be dissociated such that the dorsal region is associated with the motor cortex, whereas the ventral aspect is associated with the prefrontal cortex. However, whether dentato-thalamo-cortical networks differ across adulthood remains unknown. Here, using a large adult sample (n = 590) from the Cambridge Center for Ageing and Neuroscience, we investigated dentate connectivity across adulthood. We replicated past work showing dissociable resting state networks in the dorsal and ventral aspects of the dentate. In both seeds, we demonstrated that connectivity is lower with advanced age, indicating that connectivity differences extend beyond the cerebellar cortex. Finally, we demonstrated sex differences in dentate connectivity. This expands our understanding of cerebellar circuitry in advanced age and underscores the potential importance of this structure in age-related performance differences.

Cognition and action: a latent variable approach to study contributions of executive functions to motor control in older adults.

Aging is associated with profound alterations in motor control that may be exacerbated by age-related executive functioning decline. Executive functions span multiple facets including inhibition (suppressing unwanted response tendencies), shifting (switching between cognitive operations), and updating (managing working memory content). However, comprehensive studies regarding the contributions of single facets of executive functioning to movement control in older adults are still lacking. A battery of nine neuropsychological tasks was administered to n = 92 older adults in order to derive latent factors for inhibition, shifting, and updating by structural equation modeling. A bimanual task was used to assess complex motor control. A sample of n = 26 young adults served as a control group to verify age-related performance differences. In older adults, structural equation models revealed that performance on the most challenging condition of the complex motor task was best predicted by the updating factor and by general executive functioning performance. These data suggest a central role for working memory updating in complex motor performance and contribute to our understanding of how individual differences in executive functioning relate to movement control in older adults.

Cortical thickness in the right inferior frontal gyrus mediates age-related performance differences on an item-method directed forgetting task

Evidence suggests that older adults have difficulty relative to younger adults in forgetting irrelevant information. Here we sought to understand the physical basis of this deficit by investigating the relationship between cortical thickness and intentional forgetting, using an item-method directed forgetting task. We tested younger (n=44) and older (n=54) adults' memories for words that they were instructed to either remember or to forget, and then extracted cortical thickness values from brain regions previously shown, using functional neuroimaging, to be associated with memory suppression, including the right inferior frontal gyrus, the right postcentral gyrus and the left superior/middle frontal gyrus. Results from a parallel mediation model indicated that variations in cortical thickness in the right inferior frontal gyrus, but not the right postcentral gyrus or left superior/middle frontal gyrus, partially explained age-related differences in directed forgetting: older adults with thinner cortices in this area showed worse forgetting ability. This is the first study to explore how neuromorphological differences affect the ability to intentionally suppress items in memory. The results suggest that age-related differences in directed forgetting may be partly driven by cortical thickness in a brain structure known to be functionally involved in directed forgetting, and inhibitory control more broadly, supporting a contribution of deficient inhibition to this phenomenon.

The effect of vascular health factors on white matter microstructure mediates age-related differences in executive function performance

Even within healthy aging, vascular risk factors can detrimentally influence cognition, with executive functions (EF) particularly vulnerable. Fronto-parietal white matter (WM) connectivity in part, supports EF and may be particularly sensitive to vascular risk. Here, we utilized structural equation modeling in 184 healthy adults (aged 20–94 years of age) to test the hypotheses that: 1) fronto-parietal WM microstructure mediates age effects on EF; 2) higher blood pressure (BP) and white matter hyperintensity (WMH) burden influences this association. All participants underwent comprehensive cognitive and neuropsychological testing including tests of processing speed, executive function (with a focus on tasks that require switching and inhibition) and completed an MRI scanning session that included FLAIR imaging for semi-automated quantification of white matter hyperintensity burden and diffusion-weighted imaging for tractography. Structural equation models were specified with age (as a continuous variable) and blood pressure predicting within-tract WMH burden and fractional anisotropy predicting executive function and processing speed. Results indicated that fronto-parietal white matter of the genu of the corpus collosum, superior longitudinal fasciculus, and the inferior frontal occipital fasciculus (but not cortico-spinal tract) mediated the association between age and EF. Additionally, increased systolic blood pressure and white matter hyperintensity burden within these white matter tracts contribute to worsening white matter health and are important factors underlying age-brain-behavior associations. These findings suggest that aging brings about increases in both BP and WMH burden, which may be involved in the degradation of white matter connectivity and in turn, negatively impact executive functions as we age.

Muscle Performance Changes with Age in Active Women.

The purpose of this study was to examine age-related differences in muscle performance in women divided into young (YW, 20–39 years, n = 29) middle-aged (MAW, 40–59 years, n = 33), and older (OW, ≥60 years, n = 40) age groups. Methods: Hand grip strength, vertical jump performance, and knee extensor (KE) strength (0 deg/s, 60 deg/s, and 240 deg/s), speed of movement (SoM; at 1 Nm, 20%, 40%, and 60% isometric strength), and endurance (30-repetition test at 60 degs/s and 240 deg/s) were assessed. Computed tomography-acquired muscle cross-sectional area (mCSA) was measured and included to determine specific strength (KE strength/mCSA). Results: Hand grip strength was similar across groups, while jump performance declined with age (YW and MAW > OW, p < 0.001). KE strength declined significantly with age (all conditions p < 0.01), while specific strength was similar across groups. SoM was significantly higher for YW and MAW compared to OW (both p < 0.01). An age × velocity interaction revealed YW KE endurance was similar between conditions, whereas MAW and OW displayed significantly better endurance during the 60 deg/s condition. OW displayed impaired KE endurance at 240 deg/s (vs. YW and MAW, p < 0.01) but improved at 60 deg/s (vs. YW, p < 0.01). Dynamic torque decline increased with age (YW < OW, p = 0.03) and was associated with intramuscular adipose tissue (r = 0.21, p = 0.04). Conclusions: Performance declines were most evident among OW, but few performance deficits had emerged in MAW. Interestingly, strength declines disappeared after normalizing to mCSA and endurance appears to be velocity-dependent.

Age-related differences in memory for “who,” “when,” and “where” are detectable in middle-aged adults

ABSTRACT Our study examined age-related differences across the adult lifespan using a recently developed test assessing memory for “who, when, and where” in addition to associations among these elements. Young (ages 18–25), middle-aged (ages 40–55), and older adults (ages 60+) were asked to remember a sequence of pictures of different faces paired with different places and place the pairs in the correct sequence. Young adults remembered significantly mores face-place pairs in the correct sequence than middle-aged (p < .05) and older adults (p < .05), but there were no significant differences between middle-aged and older adults. Furthermore, young adults remembered significantly more face-place pairs irrespective of sequence than older adults (p < .05). However, there were no other significant differences among the groups.Using a rapidly administered test that integrates aspects of everyday episodic memory, we found evidence for age-related differences in test performance beginning in middle age.

Fitness and Performance Testing of Male and Female Beach Soccer Players-A Preliminary Investigation.

Purpose: This study aimed to compare performance on sand and a firm surface and to describe the physical capacity of male and female beach soccer players.Methods: Sixty-six male and 29 female competitive beach soccer players voluntarily participated in this study. Firstly, within-subjects test scores were compared to scores on a firm surface (criterion validity; n = 15 men) and reconducted on a second occasion (reliability; n = 51 men). Secondly, the best score on sand was retained to compare test performance between ages (classified as below 20, 20–30, and above 30 years) and sexes. Performance assessments included sprint time over 5 and 15 m (once on a firm surface and twice on sand), standing long jump (SLJ, once on a firm surface and twice on sand) and Yo-Yo intermittent recovery level 1 (Yo-Yo IR1, once on a firm surface and once on sand; only data for men were available).Results: Five-m sprint and Yo-Yo IR1 performance on sand were not correlated to performance on a firm surface (P > 0.05). Test-retest reliability was acceptable for the 15-m sprint and SLJ tests (ICC > 0.90; CV < 5%). Performance in 15-m sprint and maximal sprinting speed were moderately lower in male players aged above 30 years. compared to players aged below 30 years (d = 0.35–0.42; P < 0.05). Irrespective of the age group, weight-bearing power-based performance mass was moderately to very largely higher in male players than in female players (d = 0.42–0.88; P < 0.05).Conclusions: The lack of a consistent relationship between performance on sand and on a firm surface might indicate the need to develop specific test batteries for sand-based athletes. Age-related differences in physical performance were evident only in sprint capacity. Further studies are warranted to elucidate our preliminary findings and to develop the sand specific tests.

Alpha modulation in younger and older adults during distracted encoding.

To successfully encode information into long-term memory, we need top-down control to focus our attention on target stimuli. This attentional focus is achieved by the modulation of sensory neuronal excitability through alpha power. Failure to modulate alpha power and to inhibit distracting information has been reported in older adults during attention and working memory tasks. Given that alpha power during encoding can predict subsequent memory performance, aberrant oscillatory modulations might play a role in age-related memory deficits. However, it is unknown whether there are age-related differences in memory performance or alpha modulation when encoding targets with distraction. Here we show that both older and younger adults are able to encode targets paired with distractors and that the level of alpha power modulation during encoding predicted recognition success. Even though older adults showed signs of higher distractibility, this did not harm their episodic memory for target information. Also, we demonstrate that older adults only modulated alpha power during high distraction, both by enhancing target processing and inhibiting distractor processing. These results indicate that both younger and older adults are able to employ the same inhibitory control mechanisms successfully, but that older adults fail to call upon these when distraction is minimal. The findings of this study give us more insight into the mechanisms involved in memory encoding across the lifespan.

Idea selection for propositional language production

ABSTRACT The ability to select an idea from an array of competing options is critical for successful propositional language production, and deficient idea selection contributes to propositional language impairments in clinical populations. We investigate whether three clinical idea selection tasks are sensitive to selection demands in neurologically unimpaired adults, and whether performance relates to age. 154 neurologically normal adults aged 18–89 years completed a neuropsychological baseline and three idea selection tasks. Stimuli either activated a dominant response or multiple competing response options. All three idea selection tasks were sensitive to selection demands in terms of reaction times but not errors. Older age was associated with greater effects of selection demands on Sentence Completion task performance only. Exploratory analyses revealed a potential role of executive functioning. Overall, we demonstrate that clinical idea selection tasks are sensitive to idea selection demands in a non-clinical sample, and show some age-related differences in performance.

Age-dependent statistical learning trajectories reveal differences in information weighting.

Statistical learning (SL) is the ability to generate predictions based on probabilistic dependencies in the environment, an ability that is present throughout life. The effect of aging on SL is still unclear. Here, we explore statistical learning in healthy adults (40 younger and 40 older). The novel paradigm tracks learning trajectories and shows age-related differences in overall performance, yet similarities in learning rates. Bayesian models reveal further differences between younger and older adults in dealing with uncertainty in this probabilistic SL task. We test computational models of 3 different learning strategies: (a) Win-Stay, Lose-Shift, (b) Delta Rule Learning, (c) Information Weights to explore whether they capture age-related differences in performance and learning in the present task. A likely candidate mechanism emerges in the form of age-dependent differences in information weights, in which young adults more readily change their behavior, but also show disproportionally strong reactions toward erroneous predictions. With lower but more balanced information weights, older adults show slower behavioral adaptation but eventually arrive at more stable and accurate representations of the underlying transitional probability matrix. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

An investigation of the influence of age on eye fatigue and hand operation performance in a virtual environment

Only a few studies in the literature have focused on the effects of age on fatigue susceptibility and hand operation performance in virtual environments, and even less research has been carried out focusing on older adults. This study aimed to assess the hand movement performance in a virtual environment with two group measures, including visual fatigue and depth perception. A total of 10 adults (5 young adults and 5 older adults) participated in this study. This study was conducted in the following order: pre-CFF measurement, performance of a Fitts’ Law task with stereoscopic viewing, post-CFF measurement every 10 min (during task), and recording of task movement time and error rate after each condition of the task. This study found significant effects of age and task index of difficulty on hand movement. Compared to the older adults, the young adults appeared to have better hand movement performance. Regarding eye fatigue, eye fatigue was significantly higher at binocular parallax of 9 cm than at 6 cm and 3 cm. Surprisingly, age had a significant effect on hand movement performance but not on visual fatigue. This study suggests that the operation time should be less than 20 min and that parallax should be 6 cm (visual angle = 1.38 degrees) to prevent visual fatigue when movement tasks are performed in a virtual environment. These data highlight the potential for age-related differences in hand movement performance during the performance of tasks in which fast and accurate selection are required in combination with the manipulation of 3D objects in a virtual environment, and the study provides directions for further exploration.